Explore the Role of the rs1801133-PPARG Pathway in the H-type Hypertension
In this study, we first tested the association between rs1801133 genotypes and Hcy level in H-type hypertension using clinical profiles collected from 203 patients before and after the treatment using enalapril maleate and folic acid tablets (EMFAT). Then, we constructed a literature-based pathway analysis to explore the role of the rs1801133-PPARG signaling pathway in H-type hypertension and its treatment. Although presented similar blood pressure, the patients with TT genotype of rs1801133 were much younger (p value <0.05) and significantly higher in Hcy levels (x 2 = 6.11 and p < 0.005) than that in the CC and CT ...
Source: PPAR Research - March 31, 2022 Category: Genetics & Stem Cells Authors: Xiuwen Liang Tingting He Lihong Gao Libo Wei Di Rong Yu Zhang Yu Liu Source Type: research
