Angiotensin receptor-neprilysin inhibitors and cardiac remodeling
Braz J Med Biol Res. 2023 Apr 7;56:e12616. doi: 10.1590/1414-431X2023e12616. eCollection 2023.ABSTRACTThe aim of this study was to determine how sacubitril/valsartan compared with valsartan in an outpatient setting affects left ventricular remodeling in heart failure with reduced ejection fraction and functional (or secondary) mitral regurgitation (SMR) due to the effect of dual inhibition of the renin-angiotensin system and neprilysin. The outpatient study included 90 patients with chronic SMR who were followed up for 12 months. They received sacubitril/valsartan or valsartan instead of the more commonly used angiotensin-...
Source: Braz J Med Biol Res - April 12, 2023 Category: Research Authors: A S Ryazanov E V Shikh M V Makarovskaya A A Kudryavtsev Source Type: research

Angiotensin receptor-neprilysin inhibitors and cardiac remodeling
Braz J Med Biol Res. 2023 Apr 7;56:e12616. doi: 10.1590/1414-431X2023e12616. eCollection 2023.ABSTRACTThe aim of this study was to determine how sacubitril/valsartan compared with valsartan in an outpatient setting affects left ventricular remodeling in heart failure with reduced ejection fraction and functional (or secondary) mitral regurgitation (SMR) due to the effect of dual inhibition of the renin-angiotensin system and neprilysin. The outpatient study included 90 patients with chronic SMR who were followed up for 12 months. They received sacubitril/valsartan or valsartan instead of the more commonly used angiotensin-...
Source: Brazilian Journal of Medical and Biological Research - April 12, 2023 Category: Research Authors: A S Ryazanov E V Shikh M V Makarovskaya A A Kudryavtsev Source Type: research

Angiotensin receptor-neprilysin inhibitors and cardiac remodeling
Braz J Med Biol Res. 2023 Apr 7;56:e12616. doi: 10.1590/1414-431X2023e12616. eCollection 2023.ABSTRACTThe aim of this study was to determine how sacubitril/valsartan compared with valsartan in an outpatient setting affects left ventricular remodeling in heart failure with reduced ejection fraction and functional (or secondary) mitral regurgitation (SMR) due to the effect of dual inhibition of the renin-angiotensin system and neprilysin. The outpatient study included 90 patients with chronic SMR who were followed up for 12 months. They received sacubitril/valsartan or valsartan instead of the more commonly used angiotensin-...
Source: Braz J Med Biol Res - April 12, 2023 Category: Research Authors: A S Ryazanov E V Shikh M V Makarovskaya A A Kudryavtsev Source Type: research

Angiotensin receptor-neprilysin inhibitors and cardiac remodeling
Braz J Med Biol Res. 2023 Apr 7;56:e12616. doi: 10.1590/1414-431X2023e12616. eCollection 2023.ABSTRACTThe aim of this study was to determine how sacubitril/valsartan compared with valsartan in an outpatient setting affects left ventricular remodeling in heart failure with reduced ejection fraction and functional (or secondary) mitral regurgitation (SMR) due to the effect of dual inhibition of the renin-angiotensin system and neprilysin. The outpatient study included 90 patients with chronic SMR who were followed up for 12 months. They received sacubitril/valsartan or valsartan instead of the more commonly used angiotensin-...
Source: Brazilian Journal of Medical and Biological Research - April 12, 2023 Category: Research Authors: A S Ryazanov E V Shikh M V Makarovskaya A A Kudryavtsev Source Type: research

Angiotensin receptor-neprilysin inhibitors and cardiac remodeling
Braz J Med Biol Res. 2023 Apr 7;56:e12616. doi: 10.1590/1414-431X2023e12616. eCollection 2023.ABSTRACTThe aim of this study was to determine how sacubitril/valsartan compared with valsartan in an outpatient setting affects left ventricular remodeling in heart failure with reduced ejection fraction and functional (or secondary) mitral regurgitation (SMR) due to the effect of dual inhibition of the renin-angiotensin system and neprilysin. The outpatient study included 90 patients with chronic SMR who were followed up for 12 months. They received sacubitril/valsartan or valsartan instead of the more commonly used angiotensin-...
Source: Braz J Med Biol Res - April 12, 2023 Category: Research Authors: A S Ryazanov E V Shikh M V Makarovskaya A A Kudryavtsev Source Type: research

Angiotensin receptor-neprilysin inhibitors and cardiac remodeling
Braz J Med Biol Res. 2023 Apr 7;56:e12616. doi: 10.1590/1414-431X2023e12616. eCollection 2023.ABSTRACTThe aim of this study was to determine how sacubitril/valsartan compared with valsartan in an outpatient setting affects left ventricular remodeling in heart failure with reduced ejection fraction and functional (or secondary) mitral regurgitation (SMR) due to the effect of dual inhibition of the renin-angiotensin system and neprilysin. The outpatient study included 90 patients with chronic SMR who were followed up for 12 months. They received sacubitril/valsartan or valsartan instead of the more commonly used angiotensin-...
Source: Brazilian Journal of Medical and Biological Research - April 12, 2023 Category: Research Authors: A S Ryazanov E V Shikh M V Makarovskaya A A Kudryavtsev Source Type: research

Angiotensin receptor-neprilysin inhibitors and cardiac remodeling
Braz J Med Biol Res. 2023 Apr 7;56:e12616. doi: 10.1590/1414-431X2023e12616. eCollection 2023.ABSTRACTThe aim of this study was to determine how sacubitril/valsartan compared with valsartan in an outpatient setting affects left ventricular remodeling in heart failure with reduced ejection fraction and functional (or secondary) mitral regurgitation (SMR) due to the effect of dual inhibition of the renin-angiotensin system and neprilysin. The outpatient study included 90 patients with chronic SMR who were followed up for 12 months. They received sacubitril/valsartan or valsartan instead of the more commonly used angiotensin-...
Source: Braz J Med Biol Res - April 12, 2023 Category: Research Authors: A S Ryazanov E V Shikh M V Makarovskaya A A Kudryavtsev Source Type: research

Angiotensin receptor-neprilysin inhibitors and cardiac remodeling
Braz J Med Biol Res. 2023 Apr 7;56:e12616. doi: 10.1590/1414-431X2023e12616. eCollection 2023.ABSTRACTThe aim of this study was to determine how sacubitril/valsartan compared with valsartan in an outpatient setting affects left ventricular remodeling in heart failure with reduced ejection fraction and functional (or secondary) mitral regurgitation (SMR) due to the effect of dual inhibition of the renin-angiotensin system and neprilysin. The outpatient study included 90 patients with chronic SMR who were followed up for 12 months. They received sacubitril/valsartan or valsartan instead of the more commonly used angiotensin-...
Source: Brazilian Journal of Medical and Biological Research - April 12, 2023 Category: Research Authors: A S Ryazanov E V Shikh M V Makarovskaya A A Kudryavtsev Source Type: research

Angiotensin receptor-neprilysin inhibitors and cardiac remodeling
Braz J Med Biol Res. 2023 Apr 7;56:e12616. doi: 10.1590/1414-431X2023e12616. eCollection 2023.ABSTRACTThe aim of this study was to determine how sacubitril/valsartan compared with valsartan in an outpatient setting affects left ventricular remodeling in heart failure with reduced ejection fraction and functional (or secondary) mitral regurgitation (SMR) due to the effect of dual inhibition of the renin-angiotensin system and neprilysin. The outpatient study included 90 patients with chronic SMR who were followed up for 12 months. They received sacubitril/valsartan or valsartan instead of the more commonly used angiotensin-...
Source: Braz J Med Biol Res - April 12, 2023 Category: Research Authors: A S Ryazanov E V Shikh M V Makarovskaya A A Kudryavtsev Source Type: research

Angiotensin receptor-neprilysin inhibitors and cardiac remodeling
Braz J Med Biol Res. 2023 Apr 7;56:e12616. doi: 10.1590/1414-431X2023e12616. eCollection 2023.ABSTRACTThe aim of this study was to determine how sacubitril/valsartan compared with valsartan in an outpatient setting affects left ventricular remodeling in heart failure with reduced ejection fraction and functional (or secondary) mitral regurgitation (SMR) due to the effect of dual inhibition of the renin-angiotensin system and neprilysin. The outpatient study included 90 patients with chronic SMR who were followed up for 12 months. They received sacubitril/valsartan or valsartan instead of the more commonly used angiotensin-...
Source: Brazilian Journal of Medical and Biological Research - April 12, 2023 Category: Research Authors: A S Ryazanov E V Shikh M V Makarovskaya A A Kudryavtsev Source Type: research

Angiotensin receptor-neprilysin inhibitors and cardiac remodeling
Braz J Med Biol Res. 2023 Apr 7;56:e12616. doi: 10.1590/1414-431X2023e12616. eCollection 2023.ABSTRACTThe aim of this study was to determine how sacubitril/valsartan compared with valsartan in an outpatient setting affects left ventricular remodeling in heart failure with reduced ejection fraction and functional (or secondary) mitral regurgitation (SMR) due to the effect of dual inhibition of the renin-angiotensin system and neprilysin. The outpatient study included 90 patients with chronic SMR who were followed up for 12 months. They received sacubitril/valsartan or valsartan instead of the more commonly used angiotensin-...
Source: Braz J Med Biol Res - April 12, 2023 Category: Research Authors: A S Ryazanov E V Shikh M V Makarovskaya A A Kudryavtsev Source Type: research

Hospitalization Provides An Opportunity For Sacubitril/valsartan Initiation
Sacubitril/valsartan reduces the risk of cardiovascular death and hospitalization when compared to enalapril, while providing a greater reduction in NT-proBNP and improved cardiac volume and function Additionally, it has shown to be safe to initiate in hospitalized patients Despite HFSA guideline recommendations to utilize sacubitril/valsartan as first line HF therapy, national utilization rates of 14% have been described Purpose: The purpose of this study is to identify barriers to initiation and continuation of sacubitril/valsartan in hospitalized HFrEF patients (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - April 1, 2023 Category: Cardiology Authors: Adam Smith, Annette Augustine, Katherine Crawford, Tara Schreck, Anupam Basuray Tags: 302 Source Type: research

Risk factors of dementia in patients with cerebral vascular diseases based on Taiwan National Health Insurance data
CONCLUSION: Depression, osteoporosis and the use of enalapril were associated with a higher risk of dementia, while nitroglycerin might be a protecting factor for dementia, in subjects with cerebrovascular diseases without mention of cerebral infarction. (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - March 22, 2023 Category: Geriatrics Source Type: research

Risk factors of dementia in patients with cerebral vascular diseases based on Taiwan National Health Insurance data
CONCLUSION: Depression, osteoporosis and the use of enalapril were associated with a higher risk of dementia, while nitroglycerin might be a protecting factor for dementia, in subjects with cerebrovascular diseases without mention of cerebral infarction.PMID:36948166 | DOI:10.1159/000530102 (Source: Atherosclerosis)
Source: Atherosclerosis - March 22, 2023 Category: Cardiology Authors: Bin Zhou Cheng-Li Lin Shinsuke Kojima Masanori Fukushima Chung Y Hsu Source Type: research

Risk factors of dementia in patients with cerebral vascular diseases based on Taiwan National Health Insurance data
CONCLUSION: Depression, osteoporosis and the use of enalapril were associated with a higher risk of dementia, while nitroglycerin might be a protecting factor for dementia, in subjects with cerebrovascular diseases without mention of cerebral infarction.PMID:36948166 | DOI:10.1159/000530102 (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - March 22, 2023 Category: Psychiatry Authors: Bin Zhou Cheng-Li Lin Shinsuke Kojima Masanori Fukushima Chung Y Hsu Source Type: research