The association between ACE inhibitors and psoriasis based on the drug-targeted Mendelian randomization and real-world pharmacovigilance analyses
CONCLUSIONS: Our integrative study verified that ACEIs, especially ramipril, trandolapril, perindopril, lisinopril, and enalapril, tended to increase the risk of psoriasis statistically.PMID:38078460 | DOI:10.1080/17512433.2023.2292605 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - December 11, 2023 Category: Drugs & Pharmacology Authors: Qiubai Jin Feihong Ren Ping Song Source Type: research
The association between ACE inhibitors and psoriasis based on the drug-targeted Mendelian randomization and real-world pharmacovigilance analyses
CONCLUSIONS: Our integrative study verified that ACEIs, especially ramipril, trandolapril, perindopril, lisinopril, and enalapril, tended to increase the risk of psoriasis statistically.PMID:38078460 | DOI:10.1080/17512433.2023.2292605 (Source: Expert Review of Clinical Pharmacology)
Source: Expert Review of Clinical Pharmacology - December 11, 2023 Category: Drugs & Pharmacology Authors: Qiubai Jin Feihong Ren Ping Song Source Type: research
The association between ACE inhibitors and psoriasis based on the drug-targeted Mendelian randomization and real-world pharmacovigilance analyses
CONCLUSIONS: Our integrative study verified that ACEIs, especially ramipril, trandolapril, perindopril, lisinopril, and enalapril, tended to increase the risk of psoriasis statistically.PMID:38078460 | DOI:10.1080/17512433.2023.2292605 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - December 11, 2023 Category: Drugs & Pharmacology Authors: Qiubai Jin Feihong Ren Ping Song Source Type: research
The association between ACE inhibitors and psoriasis based on the drug-targeted Mendelian randomization and real-world pharmacovigilance analyses
CONCLUSIONS: Our integrative study verified that ACEIs, especially ramipril, trandolapril, perindopril, lisinopril, and enalapril, tended to increase the risk of psoriasis statistically.PMID:38078460 | DOI:10.1080/17512433.2023.2292605 (Source: Expert Review of Clinical Pharmacology)
Source: Expert Review of Clinical Pharmacology - December 11, 2023 Category: Drugs & Pharmacology Authors: Qiubai Jin Feihong Ren Ping Song Source Type: research
EE618 Sacubitril/Valsartan Vs Enalapril Use in Hospitalized Patients with Heart Failure in Spain
Heart failure is the most common reason for admission in almost all hospitals in Spain. Heart failure admissions are related to poor outcomes. The use of sacubitril/valsartan (sac/val) in hospitalized patients showed a greater benefit in the PIONEER-HF trial. Even though sac/val has demonstrated its effectiveness among patients hospitalized for HFrEF, its prescription remains restricted during hospital admissions. The aim of this study is to evaluate the cost-effectiveness in the inpatient settings of Sac/val in patients with HFrEF from the perspective of the Spanish Health System. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: F.J. Parrondo Garc ía, A. García-Quintana Source Type: research
EE465 Sacubitril/Valsartan Vs Enalapril Use in the Outpatient Facilities Setting in Spain
Heart failure is a highly prevalent pathology that greatly affects the survival and quality of life of patients. Despite sacubitril/valsartan (sac/val) has demonstrated its effectiveness versus enalapril among patients with heart failure with reduced ejection fraction (HFrEF) in the clinical trials, its prescription remains restricted due to being more expensive than other treatment alternatives like the ACE inhibitors. The aim of this study is to evaluate the cost-effectiveness in outpatient settings of sac/val in patients with HFrEF from the perspective of the Spanish Health System. (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: F.J. Parrondo Garc ía, A. García-Quintana Source Type: research
Efficacy and Safety of Sacubitril/Valsartan in Japanese Patients With Heart Failure According to Baseline Systolic Blood Pressure - Results From a Subgroup Analysis of the PARALLEL-HF Study
CONCLUSIONS: The efficacy of sacubitril/valsartan compared with enalapril was consistent across baseline SBP tertiles in Japanese patients from the PARALLEL-HF study. Hypotension-related events were more common in patients treated with sacubitril/valsartan with lower SBP.PMID:37989299 | DOI:10.1253/circj.CJ-23-0349 (Source: Circulation Journal)
Source: Circulation Journal - November 21, 2023 Category: Cardiology Authors: Hiroyuki Tsutsui Shin-Ichi Momomura Yoshihiko Saito Hiroshi Ito Kazuhiro Yamamoto Yasushi Sakata Tomomi Ohishi Takayuki Iimori Toshihito Kitamura PARALLEL-HF Investigators Source Type: research
Efficacy and Safety of Sacubitril/Valsartan in Japanese Patients With Heart Failure According to Baseline Systolic Blood Pressure - Results From a Subgroup Analysis of the PARALLEL-HF Study
CONCLUSIONS: The efficacy of sacubitril/valsartan compared with enalapril was consistent across baseline SBP tertiles in Japanese patients from the PARALLEL-HF study. Hypotension-related events were more common in patients treated with sacubitril/valsartan with lower SBP.PMID:37989299 | DOI:10.1253/circj.CJ-23-0349 (Source: Circulation Journal)
Source: Circulation Journal - November 21, 2023 Category: Cardiology Authors: Hiroyuki Tsutsui Shin-Ichi Momomura Yoshihiko Saito Hiroshi Ito Kazuhiro Yamamoto Yasushi Sakata Tomomi Ohishi Takayuki Iimori Toshihito Kitamura PARALLEL-HF Investigators Source Type: research
Efficacy and Safety of Sacubitril/Valsartan in Japanese Patients With Heart Failure According to Baseline Systolic Blood Pressure - Results From a Subgroup Analysis of the PARALLEL-HF Study
CONCLUSIONS: The efficacy of sacubitril/valsartan compared with enalapril was consistent across baseline SBP tertiles in Japanese patients from the PARALLEL-HF study. Hypotension-related events were more common in patients treated with sacubitril/valsartan with lower SBP.PMID:37989299 | DOI:10.1253/circj.CJ-23-0349 (Source: Circulation Journal)
Source: Circulation Journal - November 21, 2023 Category: Cardiology Authors: Hiroyuki Tsutsui Shin-Ichi Momomura Yoshihiko Saito Hiroshi Ito Kazuhiro Yamamoto Yasushi Sakata Tomomi Ohishi Takayuki Iimori Toshihito Kitamura PARALLEL-HF Investigators Source Type: research
Efficacy and Safety of Sacubitril/Valsartan in Japanese Patients With Heart Failure According to Baseline Systolic Blood Pressure - Results From a Subgroup Analysis of the PARALLEL-HF Study
CONCLUSIONS: The efficacy of sacubitril/valsartan compared with enalapril was consistent across baseline SBP tertiles in Japanese patients from the PARALLEL-HF study. Hypotension-related events were more common in patients treated with sacubitril/valsartan with lower SBP.PMID:37989299 | DOI:10.1253/circj.CJ-23-0349 (Source: Circulation Journal)
Source: Circulation Journal - November 21, 2023 Category: Cardiology Authors: Hiroyuki Tsutsui Shin-Ichi Momomura Yoshihiko Saito Hiroshi Ito Kazuhiro Yamamoto Yasushi Sakata Tomomi Ohishi Takayuki Iimori Toshihito Kitamura PARALLEL-HF Investigators Source Type: research
Associations of Biomarkers of Tubular Injury and Inflammation with Biopsy Features in Type 1 Diabetes
CONCLUSIONS: Biomarkers of tubular injury and inflammation were associated with kidney structural parameters early type 1 diabetes and may be indicators of kidney disease risk.PMID:37871959 | DOI:10.2215/CJN.0000000000000333 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - October 23, 2023 Category: Urology & Nephrology Authors: Christine P Limonte David K Prince Andrew N Hoofnagle Andrzej Galecki Irl B Hirsch Frances Tian Sushrut S Waikar Helen C Looker Robert G Nelson Alessandro Doria Michael Mauer Bryan R Kestenbaum Ian H de Boer Source Type: research
Impact of a combination of pimobendan, furosemide, and enalapril on heart rate variability in naturally occurring, symptomatic, myxomatous mitral valve degeneration dogs
Pimobendan, diuretics, and an angiotensin-converting enzyme inhibitor (ACEi) are widely used for the management of chronic valvular heart disease in dogs; however, the effects of that combination on heart rate... (Source: BMC Veterinary Research)
Source: BMC Veterinary Research - October 12, 2023 Category: Veterinary Research Authors: Prapawadee Pirintr, Nakkawee Saengklub, Pakit Boonpala, Robert L. Hamlin and Anusak Kijtawornrat Tags: Research Source Type: research
Safety and efficacy of intralesional injection of enalapril versus triamcinolone acetonide in the treatment of keloids
CONCLUSIONS: Both enalapril and TAA had the same clinical effect. Enalapril could be a safe alternative to steroids in the treatment of keloid and hypertrophic scars. Further studies on enalapril are needed on a large sample of patients with further focus on the mechanism of this innovative drug.PMID:37749966 (Source: Acta Dermatovenerologica Alpina, Panonica, et Adriatica)
Source: Acta Dermatovenerologica Alpina, Panonica, et Adriatica - September 26, 2023 Category: Dermatology Authors: Basma Hamada Mohamed Samar Eltahlawy Walaa Ahmed Marzouk Noha E Mohamad Source Type: research
