Beyond Emergence: Understanding postoperative Cognitive Dysfunction (POCD).
PMID: 30028379 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 23, 2018 Category: Anesthesiology Authors: Nathan N Tags: Anesth Analg Source Type: research

Bubble Trouble: Venous Air Embolism in Endoscopic Retrograde Cholangiopancreatography.
PMID: 30028380 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 23, 2018 Category: Anesthesiology Authors: Wanderer JP, Nathan N Tags: Anesth Analg Source Type: research

Rashomon Effect and the Contradiction of Data, Practice, and Regulations.
PMID: 30028381 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 23, 2018 Category: Anesthesiology Authors: Shander A, Gross I Tags: Anesth Analg Source Type: research

Agreement Between Transesophageal Echocardiography and Thermodilution-Based Cardiac Output.
PMID: 30028382 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 23, 2018 Category: Anesthesiology Authors: Millan PD, Thiele RH Tags: Anesth Analg Source Type: research

The Costs and Costing of Regulatory Compliance.
PMID: 30028383 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 23, 2018 Category: Anesthesiology Authors: Glick DB Tags: Anesth Analg Source Type: research

Vascular Air Embolism and Endoscopy: Every Bubble Matters.
PMID: 30028384 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 23, 2018 Category: Anesthesiology Authors: Prielipp RC, Brull SJ Tags: Anesth Analg Source Type: research

Treating Chronic Pain: Is Buprenorphine the (or Even an) Answer?
PMID: 30028385 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 23, 2018 Category: Anesthesiology Authors: Sun EC, Mao J, Anderson TA Tags: Anesth Analg Source Type: research

The Mythology of Plasma Transfusion.
PMID: 30028386 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 23, 2018 Category: Anesthesiology Authors: Waters JH, Yazer MH Tags: Anesth Analg Source Type: research

Troubleshooting Technical Difficulties With Videolaryngoscope Use in Children: Initial Steps Toward Improving Tracheal Tube Passage.
PMID: 30028387 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 23, 2018 Category: Anesthesiology Authors: Jagannathan N, Sohn L, Hajduk J Tags: Anesth Analg Source Type: research

Surveying the Literature: Synopsis of Recent Key Publications.
PMID: 30028388 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 23, 2018 Category: Anesthesiology Authors: Hessel EA Tags: Anesth Analg Source Type: research

The Stress Hormone Cortisol Enhances Interferon- υ-Mediated Proinflammatory Responses of Human Immune Cells.
CONCLUSIONS: These results reveal a surprisingly robust proinflammatory interaction between the human stress response hormone cortisol and the immune activating cytokine IFN-υ. The results support an emerging physiological model with an adaptive role for cortisol, wherein acute release of cortisol suppresses early proinflammatory responses but also primes immune cells for an augmented response to a subsequent immune challenge. These findings have broad clinical implications and provide an experimental framework to examine individual differences, mechanisms, and translational implications of cortisol-enhanced immune...
Source: Anesthesia and Analgesia - July 23, 2018 Category: Anesthesiology Authors: Yeager MP, Guyre CA, Sites BD, Collins JE, Pioli PA, Guyre PM Tags: Anesth Analg Source Type: research

Do Epidural Catheter Size and Flow Rate Affect Bolus Injection Pressure in Different Programmed Intermittent Epidural Bolus Regimens? An In Vitro Study.
Abstract BACKGROUND: The optimal programmed intermittent epidural bolus regimen for labor analgesia remains unknown. Some studies indicate that better drug spread in the epidural space results from greater injection pressure; however, there is a lack of data regarding the maximum pressure generated by epidural bolus injection using different catheters and flow rates. METHODS: We evaluated the flow and pressure characteristics of 11 commonly used epidural catheters combined with 3 different infusion pumps that deliver epidural infusions according to the programmed intermittent epidural bolus regimen. Pressure ...
Source: Anesthesia and Analgesia - July 17, 2018 Category: Anesthesiology Authors: Krawczyk P, Piwowar P, Sałapa K, Lonc T, Andres J Tags: Anesth Analg Source Type: research

In Response.
PMID: 30028348 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 17, 2018 Category: Anesthesiology Authors: Nanji KC, Fain B, Morley MG, Bayes J Tags: Anesth Analg Source Type: research

Preventing Adverse Events in Cataract Surgery: Sub-Tenon's Block.
PMID: 30028349 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 17, 2018 Category: Anesthesiology Authors: Eke T, Kumar CM Tags: Anesth Analg Source Type: research

Survival Analysis and Interpretation of Time-to-Event Data: The Tortoise and the Hare.
Abstract Survival analysis, or more generally, time-to-event analysis, refers to a set of methods for analyzing the length of time until the occurrence of a well-defined end point of interest. A unique feature of survival data is that typically not all patients experience the event (eg, death) by the end of the observation period, so the actual survival times for some patients are unknown. This phenomenon, referred to as censoring, must be accounted for in the analysis to allow for valid inferences. Moreover, survival times are usually skewed, limiting the usefulness of analysis methods that assume a normal data d...
Source: Anesthesia and Analgesia - July 13, 2018 Category: Anesthesiology Authors: Schober P, Vetter TR Tags: Anesth Analg Source Type: research

In Response.
PMID: 30015654 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 13, 2018 Category: Anesthesiology Authors: McEvoy MD, Thies KC, Einav S, Ruetzler K, Moitra VK, Nunnally ME, Banerjee A, Weinberg G, Gabrielli A, Maccioli GA, Dobson G, O'Connor MF Tags: Anesth Analg Source Type: research

Special Cardiac Arrest Situations in the Perioperative Period.
PMID: 30015655 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 13, 2018 Category: Anesthesiology Authors: Veyckemans F Tags: Anesth Analg Source Type: research

Experience of Airway Management Training Program for Low- and Middle-Income Countries.
PMID: 30004930 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 11, 2018 Category: Anesthesiology Authors: Shih CY, Chang CM Tags: Anesth Analg Source Type: research

Virtual Reality Analgesia in Labor: The VRAIL Pilot Study-A Preliminary Randomized Controlled Trial Suggesting Benefit of Immersive Virtual Reality Analgesia in Unmedicated Laboring Women.
Abstract This pilot study investigated the use of virtual reality (VR) in laboring women. Twenty-seven women were observed for equivalent time during unmedicated contractions in the first stage of labor both with and without VR (order balanced and randomized). Numeric rating scale scores were collected after both study conditions. Significant decreases in sensory pain -1.5 (95% CI, -0.8 to -2.2), affective pain -2.5 (95% CI, -1.6 to -3.3), cognitive pain -3.1 (95% CI, -2.4 to -3.8), and anxiety -1.5 (95% CI, -0.8 to -2.3) were observed during VR. Results suggest that VR is a potentially effective technique for imp...
Source: Anesthesia and Analgesia - July 11, 2018 Category: Anesthesiology Authors: Frey DP, Bauer ME, Bell CL, Low LK, Hassett AL, Cassidy RB, Boyer KD, Sharar SR Tags: Anesth Analg Source Type: research

In Response.
PMID: 30004932 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 11, 2018 Category: Anesthesiology Authors: Pescod DC Tags: Anesth Analg Source Type: research

Frequency of Operative Anesthesia Care After Traumatic Injury.
Abstract BACKGROUND: Virtually all anesthesiologists care for patients who sustain traumatic injuries; however, the frequency with which operative anesthesia care is provided to this specific patient population is unclear. We sought to better understand the degree to which anesthesia providers participate in operative trauma care and how this differs by trauma center designation (levels I-V), using data from a comprehensive, regional database-the Washington State Trauma Registry (WSTR). We also sought to specifically assess operative anesthesia care frequency vis a vis the American College of Surgeons guidelines f...
Source: Anesthesia and Analgesia - July 11, 2018 Category: Anesthesiology Authors: Sunshine JE, Humbert AT, Booth B, Bowman SM, Bulger EM, Sharar SR Tags: Anesth Analg Source Type: research

A Systematic Review Evaluating Neuraxial Morphine and Diamorphine-Associated Respiratory Depression After Cesarean Delivery.
Abstract The prevalence of neuraxial opioid-induced clinically significant respiratory depression (CSRD) after cesarean delivery is unknown. We sought to review reported cases of author-reported respiratory depression (ARD) to calculate CSRD prevalence. A 6-database literature search was performed to identify ARD secondary to neuraxial morphine or diamorphine, in parturients undergoing cesarean delivery. "Highest" (definite and probable/possible) and "lowest" (definite) prevalences of CSRD were calculated. Secondary outcomes included: (1) prevalence of CSRD associated with contemporary doses of...
Source: Anesthesia and Analgesia - July 11, 2018 Category: Anesthesiology Authors: Sharawi N, Carvalho B, Habib AS, Blake L, Mhyre JM, Sultan P Tags: Anesth Analg Source Type: research

Ability of a New Smartphone Pulse Pressure Variation and Cardiac Output Application to Predict Fluid Responsiveness in Patients Undergoing Cardiac Surgery.
CONCLUSIONS: In patients undergoing cardiac surgery, PPVCAP and PPVPC both weakly predict fluid responsiveness. However, COCAP is not a good substitute for COTD and cannot be used to assess fluid responsiveness. PMID: 29985810 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 6, 2018 Category: Anesthesiology Authors: Joosten A, Boudart C, Vincent JL, Vanden Eynden F, Barvais L, Van Obbergh L, Rinehart J, Desebbe O Tags: Anesth Analg Source Type: research

Comparison of GlideScope Video Laryngoscopy and Direct Laryngoscopy for Tracheal Intubation in Neonates.
CONCLUSIONS: GS use did not decrease the TTI of all neonates and neonates with C&L grades I and II as compared to DL use; however, GS significantly decreased the TTI of neonates with C&L grades III and IV. Additionally, GS use provided improved glottic views. PMID: 29985811 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 6, 2018 Category: Anesthesiology Authors: Tao B, Liu K, Wang D, Liu Y, Yin H Tags: Anesth Analg Source Type: research

Making the Case for Case Reports.
PMID: 29979197 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 2, 2018 Category: Anesthesiology Authors: Vu MH, Weinberg G Tags: Anesth Analg Source Type: research

Informed Consent for Sugammadex and Oral Contraceptives: Through the Looking Glass.
PMID: 29979198 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - July 2, 2018 Category: Anesthesiology Authors: Webber AM, Kreso M Tags: Anesth Analg Source Type: research

Use of Hydroxocobalamin (Vitamin B12a) in Patients With Vasopressor Refractory Hypotension After Cardiopulmonary Bypass: A Case Series.
Abstract Hydroxocobalamin (vitamin B12a) is an emerging treatment for vasoplegic syndrome (VS) associated with cardiopulmonary bypass (CPB). Given its cost and scarcity, an institutional guideline for its use as a rescue treatment in cases of suspected VS was developed. Hemodynamic variables and vasopressor requirements were reviewed for a series of 24 post-CPB patients who received B12a. Favorable changes in hemodynamic parameters and vasopressor requirements were seen after B12a administration although guideline criteria for VS were inconsistently met. These findings support the continued study of B12a in patien...
Source: Anesthesia and Analgesia - July 2, 2018 Category: Anesthesiology Authors: Armour S, Armour TK, Joppa WR, Maltais S, Nelson JA, Wittwer E Tags: Anesth Analg Source Type: research

Now Serving a Trauma Victim Near You: Whole Blood for Civilian Trauma Resuscitation.
PMID: 29912048 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 20, 2018 Category: Anesthesiology Authors: Nathan N Tags: Anesth Analg Source Type: research

Factor XI Deficiency and Pregnancy: Abnormal Lab Values or Significant Risk?
PMID: 29912049 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 20, 2018 Category: Anesthesiology Authors: Wanderer JP, Nathan N Tags: Anesth Analg Source Type: research

Diversity Versus Efficiency in Surgical Practice: Making Practical Sense of Complicated Science.
PMID: 29912050 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 20, 2018 Category: Anesthesiology Authors: Dutton RP Tags: Anesth Analg Source Type: research

Transfusion of Aged Red Blood Cells in Liver Transplantation: Et tu, Brute?
PMID: 29912051 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 20, 2018 Category: Anesthesiology Authors: Tanaka KA, Mazzeffi MA, Chow JH Tags: Anesth Analg Source Type: research

New Technology, New Thinking.
PMID: 29912052 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 20, 2018 Category: Anesthesiology Authors: Dutton RP Tags: Anesth Analg Source Type: research

If Only the Practice of Evidence-Based Medicine Was as Simple as Creating Guidelines ….
If Only the Practice of Evidence-Based Medicine Was as Simple as Creating Guidelines…. Anesth Analg. 2018 Jul;127(1):9-11 Authors: Lien CA PMID: 29912053 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 20, 2018 Category: Anesthesiology Authors: Lien CA Tags: Anesth Analg Source Type: research

Anesthesiology and Palliative Care: Past, Present, and Future.
PMID: 29912054 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 20, 2018 Category: Anesthesiology Authors: Fine PG, Davis MS, Muir JC, Byas-Smith M Tags: Anesth Analg Source Type: research

National Surgical Quality Improvement Program: What Can Anesthesiologists Learn From Surgical Outcomes?
PMID: 29912055 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 20, 2018 Category: Anesthesiology Authors: Moller DH, Gan TJ Tags: Anesth Analg Source Type: research

Anesthesia Informatics Grows Up.
PMID: 29912056 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 20, 2018 Category: Anesthesiology Authors: Hofer IS, Levin MA, Simpao AF, McCormick PJ, Rothman BS Tags: Anesth Analg Source Type: research

STAT Calls: Real Data Could Improve Anesthesia Staffing Models.
PMID: 29912057 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 20, 2018 Category: Anesthesiology Authors: Adler AC, Chandrakantan A Tags: Anesth Analg Source Type: research

Adductor Canal Versus Femoral Triangle: Let Us All Get on the Same Page.
PMID: 29905612 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 12, 2018 Category: Anesthesiology Authors: Panchamia JK, Niesen AD, Amundson AW Tags: Anesth Analg Source Type: research

In Response.
PMID: 29905613 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 12, 2018 Category: Anesthesiology Authors: Glance LG, Dutton RP, Feng C, Li Y, Lustik SJ, Dick AW Tags: Anesth Analg Source Type: research

Comparing Anesthesia Durations Among Hospitals Based on Statistical Methods Described in Previous Publications in Anesthesia & Analgesia.
Comparing Anesthesia Durations Among Hospitals Based on Statistical Methods Described in Previous Publications in Anesthesia & Analgesia. Anesth Analg. 2018 Jun 12;: Authors: Dexter F, Epstein RH PMID: 29905614 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 12, 2018 Category: Anesthesiology Authors: Dexter F, Epstein RH Tags: Anesth Analg Source Type: research

In Response.
PMID: 29905615 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 12, 2018 Category: Anesthesiology Authors: Williams SR Tags: Anesth Analg Source Type: research

Implementation of Perioperative Music Using the Consolidated Framework for Implementation Research.
CONCLUSIONS: CFIR-guided implementation of perioperative music was feasible at a tertiary VA hospital, with moderate penetration in a high-risk subset of patients. Use of digital music players with preferred playlists was supported by strong evidence, tension for change, modest readiness among providers, good acceptability among patients (especially those at risk for opioid overuse), and a protocolized approach. Further study is needed to identify similar frameworks for effective knowledge-translation activities. PMID: 29905616 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 12, 2018 Category: Anesthesiology Authors: Carter JE, Pyati S, Kanach FA, Maxwell AMW, Belden CM, Shea CM, Van de Ven T, Thompson J, Hoenig H, Raghunathan K Tags: Anesth Analg Source Type: research

Impact of Clinical Guidelines on Revisits After Ambulatory Pediatric Adenotonsillectomy.
This study employs an interrupted time series design to evaluate the longitudinal effects of clinical guidelines on revisits. The outcome was defined as revisits after ambulatory tonsillectomy for privately insured patients. Data were sourced from the Truven Health Analytics MarketScan database, 2008-2015. Revisits were defined by the most prevalent complication types: hemorrhage, dehydration, pain, nausea, respiratory problem, infection, and fever. Time periods were defined by surgeries before, between, and after guidelines publication. Unadjusted odds ratios estimated associations between revisits and clinical covariates...
Source: Anesthesia and Analgesia - June 12, 2018 Category: Anesthesiology Authors: Lee HH, Dalesio NM, Lo Sasso AT, Van Cleve WC Tags: Anesth Analg Source Type: research

Repeated Measures Designs and Analysis of Longitudinal Data: If at First You Do Not Succeed-Try, Try Again.
Abstract Anesthesia, critical care, perioperative, and pain research often involves study designs in which the same outcome variable is repeatedly measured or observed over time on the same patients. Such repeatedly measured data are referred to as longitudinal data, and longitudinal study designs are commonly used to investigate changes in an outcome over time and to compare these changes among treatment groups. From a statistical perspective, longitudinal studies usually increase the precision of estimated treatment effects, thus increasing the power to detect such effects. Commonly used statistical techniques m...
Source: Anesthesia and Analgesia - June 12, 2018 Category: Anesthesiology Authors: Schober P, Vetter TR Tags: Anesth Analg Source Type: research

The Future of Activated Clotting Time?
PMID: 29889706 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 8, 2018 Category: Anesthesiology Authors: Carroll R, Mansell J, Platton S, Green L, MacCallum PK Tags: Anesth Analg Source Type: research

Postoperative Cognitive Dysfunction and Noncardiac Surgery.
Abstract Postoperative cognitive dysfunction (POCD) is an objectively measured decline in cognition postoperatively compared with preoperative function. POCD has been considered in the anesthetic and surgical literature in isolation of cognitive decline which is common in the elderly within the community and where it is labeled as mild cognitive impairment, neurocognitive disorder, or dementia. This narrative review seeks to place POCD in the broad context of cognitive decline in the general population. Cognitive change after anesthesia and surgery was described over 100 years ago, initially as delirium and dement...
Source: Anesthesia and Analgesia - June 8, 2018 Category: Anesthesiology Authors: Evered LA, Silbert BS Tags: Anesth Analg Source Type: research

A Prospective Observational Study of Anesthesia-Related Adverse Events and Postoperative Complications Occurring During a Surgical Mission in Madagascar.
CONCLUSIONS: This study adds to the scarce literature on anesthesia outcomes after mission surgery in low- and middle-income countries. We join others in calling for an international NGO anesthesia and surgical outcome registry and for all surgical NGOs to adopt international standards for the safe practice of anesthesia. PMID: 29889708 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 8, 2018 Category: Anesthesiology Authors: White MC, Barki BJ, Lerma SA, Couch SK, Alcorn D, Gillerman RG Tags: Anesth Analg Source Type: research

Adjusting the Ventilator? Not Only Size Matters!
PMID: 29889709 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 8, 2018 Category: Anesthesiology Authors: Weil G, Motamed C Tags: Anesth Analg Source Type: research

Evidence Review Conducted for the Agency for Healthcare Research and Quality Safety Program for Improving Surgical Care and Recovery: Focus on Anesthesiology for Total Knee Arthroplasty.
Abstract Enhanced recovery after surgery (ERAS) has rapidly gained popularity in a variety of surgical subspecialities. A large body of literature suggests that ERAS leads to superior outcomes, improved patient satisfaction, reduced length of hospital stay, and cost benefits, without affecting rates of readmission after surgery. These patterns have been described for patients undergoing elective total knee arthroplasty (TKA); however, adoption of ERAS to orthopedic surgery has lagged behind other surgical disciplines. The Agency for Healthcare Research and Quality, in partnership with the American College of Surge...
Source: Anesthesia and Analgesia - June 8, 2018 Category: Anesthesiology Authors: Soffin EM, Gibbons MM, Ko CY, Kates SL, Wick E, Cannesson M, Scott MJ, Wu CL Tags: Anesth Analg Source Type: research

In Response.
PMID: 29889711 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - June 8, 2018 Category: Anesthesiology Authors: Shore-Lesserson L, Ferraris V, Fitzgerald D, Baker RA Tags: Anesth Analg Source Type: research