Incidence and Mitigation of Corneal Pseudomicrocysts Induced by Antibody –Drug Conjugates (ADCs)
This study is to highlight the incidence of corneal pseudomicrocysts in FDA-approved antibody –drug conjugates (ADCs), and success of preventive therapies for pseudomicrocysts and related ocular surface adverse events (AEs).Recent FindingsADCs are an emerging class of selective cancer therapies that consist of a potent cytotoxin connected to a monoclonal antibody (mAb) that targets antigens expressed on malignant cells. Currently, there are 11 FDA-approved ADCs with over 164 in clinical trials. Various AEs have been attributed to ADCs, including ocular surface AEs (keratitis/keratopathy, dry eye, conjunctivitis, blurred ...
Source: Current Ophthalmology Reports - March 25, 2024 Category: Opthalmology Source Type: research
Comparison Between Moxifloxacin and Chloramphenicol for the Treatment of Bacterial Eye Infections
CONCLUSIONS: The lower corneal cell toxicity and the broader spectrum of antibacterial activity observed with moxifloxacin suggests its use in ophthalmic solution for the treatment of bacterial eye infections.PMID:38511104 | PMC:PMC10950741 | DOI:10.1016/j.curtheres.2024.100740 (Source: Cell Research)
Source: Cell Research - March 21, 2024 Category: Cytology Authors: Valentina Gentili Giovanni Strazzabosco Rossella Spena Sabrina Rizzo Silvia Beltrami Giovanna Schiuma Andrea Alogna Roberta Rizzo Source Type: research
Association between alopecia areata and allergic diseases: An All of Us database study
Several epidemiological studies have reported associations between alopecia areata (AA) and allergic diseases. This association may be linked to Type 2 inflammation contributing to AA pathophysiology, as suggested by a higher prevalence of atopic dermatitis, allergic rhinitis, allergic conjunctivitis, and asthma among AA individuals.1-5 Furthermore, epidemiologic evidence of AA patients experiencing seasonal relapses, comorbid atopic conditions, and elevated IgE levels may also indicate a shared immunological pathway with allergic diseases. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - March 19, 2024 Category: Allergy & Immunology Authors: Erika Tsutsui, Austin J. Piontkowski, Divija Sharma, Nicole Ramsey, Benjamin Ungar Tags: Letters Source Type: research
Association between alopecia areata and allergic diseases
Several epidemiologic studies have reported associations between alopecia areata (AA) and allergic diseases. This association may be linked to type 2 inflammation contributing to AA pathophysiology, as suggested by a higher prevalence of atopic dermatitis (AD), allergic rhinitis, allergic conjunctivitis, and asthma among individuals with AA.1 –5 Furthermore, epidemiologic evidence of patients with AA experiencing seasonal relapses, comorbid atopic conditions, and elevated IgE levels may also indicate a shared immunologic pathway with allergic diseases. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - March 19, 2024 Category: Allergy & Immunology Authors: Erika Tsutsui, Austin J. Piontkowski, Divija Sharma, Nicole Ramsey, Benjamin Ungar Tags: Letters Source Type: research
IgE to cyclophilins in pollen allergic children: epidemiological, clinical and diagnostic relevance of a neglected panallergen.
Capsule summary: Plant cyclophilins, panallergens known since decades, are still neglected. However, among Italian children with seasonal allergic rhino-conjunctivitis, cyclophilin-sIgE antibodies cause false positive reactions to pollen extracts of many clinically relevant species, mainly trees and weeds. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - March 18, 2024 Category: Allergy & Immunology Authors: Paolo Maria Matricardi, Ekaterina Potapova, Valentina Panetta, Jonas Lidholm, Lars Mattsson, Enrico Scala, Roberto Bernardini, Carlo Caffarelli, Antonella Casani, Rosa Cervone, Loredana Chini, Pasquale Comberiati, Giovanna De Castro, Michele Miraglia Del Source Type: research
Characteristics of atopic dermatitis patients using complementary and alternative medicine: A literature review
DISCUSSION: To our knowledge, this is the first literature review focusing on socio-demographic and disease determinants related to CAM use among AD patients. The lack of homogeneity in measuring tools makes it difficult to compare and synthesize the studies.PMID:38489869 | DOI:10.1016/j.annder.2024.103257 (Source: Annales de Dermatologie et de Cenereologie)
Source: Annales de Dermatologie et de Cenereologie - March 15, 2024 Category: Dermatology Authors: C Delhomme T Adam H Seiller A-C Bursztejn Source Type: research
Characteristics of atopic dermatitis patients using complementary and alternative medicine: A literature review
DISCUSSION: To our knowledge, this is the first literature review focusing on socio-demographic and disease determinants related to CAM use among AD patients. The lack of homogeneity in measuring tools makes it difficult to compare and synthesize the studies.PMID:38489869 | DOI:10.1016/j.annder.2024.103257 (Source: Annales de Dermatologie et de Venereologie)
Source: Annales de Dermatologie et de Venereologie - March 15, 2024 Category: Dermatology Authors: C Delhomme T Adam H Seiller A-C Bursztejn Source Type: research
Characteristics of atopic dermatitis patients using complementary and alternative medicine: A literature review
DISCUSSION: To our knowledge, this is the first literature review focusing on socio-demographic and disease determinants related to CAM use among AD patients. The lack of homogeneity in measuring tools makes it difficult to compare and synthesize the studies.PMID:38489869 | DOI:10.1016/j.annder.2024.103257 (Source: Annales de Dermatologie et de Cenereologie)
Source: Annales de Dermatologie et de Cenereologie - March 15, 2024 Category: Dermatology Authors: C Delhomme T Adam H Seiller A-C Bursztejn Source Type: research
Characteristics of atopic dermatitis patients using complementary and alternative medicine: A literature review
DISCUSSION: To our knowledge, this is the first literature review focusing on socio-demographic and disease determinants related to CAM use among AD patients. The lack of homogeneity in measuring tools makes it difficult to compare and synthesize the studies.PMID:38489869 | DOI:10.1016/j.annder.2024.103257 (Source: Annales de Dermatologie et de Venereologie)
Source: Annales de Dermatologie et de Venereologie - March 15, 2024 Category: Dermatology Authors: C Delhomme T Adam H Seiller A-C Bursztejn Source Type: research
Characteristics of atopic dermatitis patients using complementary and alternative medicine: A literature review
DISCUSSION: To our knowledge, this is the first literature review focusing on socio-demographic and disease determinants related to CAM use among AD patients. The lack of homogeneity in measuring tools makes it difficult to compare and synthesize the studies.PMID:38489869 | DOI:10.1016/j.annder.2024.103257 (Source: Annales de Dermatologie et de Cenereologie)
Source: Annales de Dermatologie et de Cenereologie - March 15, 2024 Category: Dermatology Authors: C Delhomme T Adam H Seiller A-C Bursztejn Source Type: research
Characteristics of atopic dermatitis patients using complementary and alternative medicine: A literature review
DISCUSSION: To our knowledge, this is the first literature review focusing on socio-demographic and disease determinants related to CAM use among AD patients. The lack of homogeneity in measuring tools makes it difficult to compare and synthesize the studies.PMID:38489869 | DOI:10.1016/j.annder.2024.103257 (Source: Annales de Dermatologie et de Venereologie)
Source: Annales de Dermatologie et de Venereologie - March 15, 2024 Category: Dermatology Authors: C Delhomme T Adam H Seiller A-C Bursztejn Source Type: research
Characteristics of atopic dermatitis patients using complementary and alternative medicine: A literature review
DISCUSSION: To our knowledge, this is the first literature review focusing on socio-demographic and disease determinants related to CAM use among AD patients. The lack of homogeneity in measuring tools makes it difficult to compare and synthesize the studies.PMID:38489869 | DOI:10.1016/j.annder.2024.103257 (Source: Annales de Dermatologie et de Cenereologie)
Source: Annales de Dermatologie et de Cenereologie - March 15, 2024 Category: Dermatology Authors: C Delhomme T Adam H Seiller A-C Bursztejn Source Type: research
Characteristics of atopic dermatitis patients using complementary and alternative medicine: A literature review
DISCUSSION: To our knowledge, this is the first literature review focusing on socio-demographic and disease determinants related to CAM use among AD patients. The lack of homogeneity in measuring tools makes it difficult to compare and synthesize the studies.PMID:38489869 | DOI:10.1016/j.annder.2024.103257 (Source: Annales de Dermatologie et de Venereologie)
Source: Annales de Dermatologie et de Venereologie - March 15, 2024 Category: Dermatology Authors: C Delhomme T Adam H Seiller A-C Bursztejn Source Type: research
Characteristics of atopic dermatitis patients using complementary and alternative medicine: A literature review
DISCUSSION: To our knowledge, this is the first literature review focusing on socio-demographic and disease determinants related to CAM use among AD patients. The lack of homogeneity in measuring tools makes it difficult to compare and synthesize the studies.PMID:38489869 | DOI:10.1016/j.annder.2024.103257 (Source: Annales de Dermatologie et de Cenereologie)
Source: Annales de Dermatologie et de Cenereologie - March 15, 2024 Category: Dermatology Authors: C Delhomme T Adam H Seiller A-C Bursztejn Source Type: research
A Comprehensive Analysis of Immunoglobulin E Levels, Allergen-Specific Sensitivities, and Clinical Manifestations in Allergic Dermatological Conditions: A Multicenter Retrospective Study in China
CONCLUSION: Relationships among age, severity of skin pruritus and lesions, and allergen-specific IgE response are complex and subtle, displaying dynamic patterns.PMID:38444403 | PMC:PMC10913895 | DOI:10.2147/CCID.S451117 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - March 6, 2024 Category: Dermatology Authors: Jian Zhao Surong Liang Boyang Zhou Min Li Linfeng Li Source Type: research
