Fundamental Aspects and Relevance of Components in Antihistamine Eye Drops
J Investig Allergol Clin Immunol. 2023 Dec;33(6):431-438. doi: 10.18176/jiaci.0963.ABSTRACTOcular allergy covers a series of immune-allergic inflammatory diseases of the ocular surface, with different degrees of involvement and severity. These pathologies are caused by a variety of IgE- and non-IgE-mediated immune mechanisms and may involve all parts of the external eye, including the conjunctiva, cornea, eyelids, tear film, and commensal flora. The most frequent is allergic conjunctivitis, a condition with different clinical forms that are classified according to the degree of involvement and the presence or absence of pr...
Source: Journal of Investigational Allergology and Clinical Immunology - December 14, 2023 Category: Allergy & Immunology Authors: R Herrero-Vanrell I J áuregui Presa A Leceta Bilbao J Montero-Iruzubieta Source Type: research

Fundamental Aspects and Relevance of Components in Antihistamine Eye Drops
J Investig Allergol Clin Immunol. 2023 Dec;33(6):431-438. doi: 10.18176/jiaci.0963.ABSTRACTOcular allergy covers a series of immune-allergic inflammatory diseases of the ocular surface, with different degrees of involvement and severity. These pathologies are caused by a variety of IgE- and non-IgE-mediated immune mechanisms and may involve all parts of the external eye, including the conjunctiva, cornea, eyelids, tear film, and commensal flora. The most frequent is allergic conjunctivitis, a condition with different clinical forms that are classified according to the degree of involvement and the presence or absence of pr...
Source: Journal of Investigational Allergology and Clinical Immunology - December 14, 2023 Category: Allergy & Immunology Authors: R Herrero-Vanrell I J áuregui Presa A Leceta Bilbao J Montero-Iruzubieta Source Type: research

The Importance of Preventing and Managing Tear Dysfunction Syndrome in Allergic Conjunctivitis and How to Tackle This Problem
J Investig Allergol Clin Immunol. 2023 Dec;33(6):439-445. doi: 10.18176/jiaci.0960.ABSTRACTTear dysfunction syndrome, also known as dry eye disease (DED), is a multifactorial disease of the ocular surface characterized by the loss of tear film homeostasis. DED shows a significant clinical overlap with ocular allergy (OA), which alters tear film homeostasis, thus predisposing the patient to DED. Both conditions constitute the most common ocular surface disorders and have a potentially severe impact on patients' quality of life. Clinical practice guidelines recommend topical therapies as first-line treatment for OA. However,...
Source: Journal of Investigational Allergology and Clinical Immunology - December 14, 2023 Category: Allergy & Immunology Authors: J Montero-Iruzubieta M C Sanchez Hernandez I D ávila A Leceta Source Type: research

The Importance of Preventing and Managing Tear Dysfunction Syndrome in Allergic Conjunctivitis and How to Tackle This Problem
J Investig Allergol Clin Immunol. 2023 Dec;33(6):439-445. doi: 10.18176/jiaci.0960.ABSTRACTTear dysfunction syndrome, also known as dry eye disease (DED), is a multifactorial disease of the ocular surface characterized by the loss of tear film homeostasis. DED shows a significant clinical overlap with ocular allergy (OA), which alters tear film homeostasis, thus predisposing the patient to DED. Both conditions constitute the most common ocular surface disorders and have a potentially severe impact on patients' quality of life. Clinical practice guidelines recommend topical therapies as first-line treatment for OA. However,...
Source: Journal of Investigational Allergology and Clinical Immunology - December 14, 2023 Category: Allergy & Immunology Authors: J Montero-Iruzubieta M C Sanchez Hernandez I D ávila A Leceta Source Type: research

Fundamental Aspects and Relevance of Components in Antihistamine Eye Drops
J Investig Allergol Clin Immunol. 2023 Dec;33(6):431-438. doi: 10.18176/jiaci.0963.ABSTRACTOcular allergy covers a series of immune-allergic inflammatory diseases of the ocular surface, with different degrees of involvement and severity. These pathologies are caused by a variety of IgE- and non-IgE-mediated immune mechanisms and may involve all parts of the external eye, including the conjunctiva, cornea, eyelids, tear film, and commensal flora. The most frequent is allergic conjunctivitis, a condition with different clinical forms that are classified according to the degree of involvement and the presence or absence of pr...
Source: Journal of Investigational Allergology and Clinical Immunology - December 14, 2023 Category: Allergy & Immunology Authors: R Herrero-Vanrell I J áuregui Presa A Leceta Bilbao J Montero-Iruzubieta Source Type: research

Fundamental Aspects and Relevance of Components in Antihistamine Eye Drops
J Investig Allergol Clin Immunol. 2023 Dec;33(6):431-438. doi: 10.18176/jiaci.0963.ABSTRACTOcular allergy covers a series of immune-allergic inflammatory diseases of the ocular surface, with different degrees of involvement and severity. These pathologies are caused by a variety of IgE- and non-IgE-mediated immune mechanisms and may involve all parts of the external eye, including the conjunctiva, cornea, eyelids, tear film, and commensal flora. The most frequent is allergic conjunctivitis, a condition with different clinical forms that are classified according to the degree of involvement and the presence or absence of pr...
Source: Journal of Investigational Allergology and Clinical Immunology - December 14, 2023 Category: Allergy & Immunology Authors: R Herrero-Vanrell I J áuregui Presa A Leceta Bilbao J Montero-Iruzubieta Source Type: research

The Importance of Preventing and Managing Tear Dysfunction Syndrome in Allergic Conjunctivitis and How to Tackle This Problem
J Investig Allergol Clin Immunol. 2023 Dec;33(6):439-445. doi: 10.18176/jiaci.0960.ABSTRACTTear dysfunction syndrome, also known as dry eye disease (DED), is a multifactorial disease of the ocular surface characterized by the loss of tear film homeostasis. DED shows a significant clinical overlap with ocular allergy (OA), which alters tear film homeostasis, thus predisposing the patient to DED. Both conditions constitute the most common ocular surface disorders and have a potentially severe impact on patients' quality of life. Clinical practice guidelines recommend topical therapies as first-line treatment for OA. However,...
Source: Journal of Investigational Allergology and Clinical Immunology - December 14, 2023 Category: Allergy & Immunology Authors: J Montero-Iruzubieta M C Sanchez Hernandez I D ávila A Leceta Source Type: research

The Importance of Preventing and Managing Tear Dysfunction Syndrome in Allergic Conjunctivitis and How to Tackle This Problem
J Investig Allergol Clin Immunol. 2023 Dec;33(6):439-445. doi: 10.18176/jiaci.0960.ABSTRACTTear dysfunction syndrome, also known as dry eye disease (DED), is a multifactorial disease of the ocular surface characterized by the loss of tear film homeostasis. DED shows a significant clinical overlap with ocular allergy (OA), which alters tear film homeostasis, thus predisposing the patient to DED. Both conditions constitute the most common ocular surface disorders and have a potentially severe impact on patients' quality of life. Clinical practice guidelines recommend topical therapies as first-line treatment for OA. However,...
Source: Journal of Investigational Allergology and Clinical Immunology - December 14, 2023 Category: Allergy & Immunology Authors: J Montero-Iruzubieta M C Sanchez Hernandez I D ávila A Leceta Source Type: research

Fundamental Aspects and Relevance of Components in Antihistamine Eye Drops
J Investig Allergol Clin Immunol. 2023 Dec;33(6):431-438. doi: 10.18176/jiaci.0963.ABSTRACTOcular allergy covers a series of immune-allergic inflammatory diseases of the ocular surface, with different degrees of involvement and severity. These pathologies are caused by a variety of IgE- and non-IgE-mediated immune mechanisms and may involve all parts of the external eye, including the conjunctiva, cornea, eyelids, tear film, and commensal flora. The most frequent is allergic conjunctivitis, a condition with different clinical forms that are classified according to the degree of involvement and the presence or absence of pr...
Source: Journal of Investigational Allergology and Clinical Immunology - December 14, 2023 Category: Allergy & Immunology Authors: R Herrero-Vanrell I J áuregui Presa A Leceta Bilbao J Montero-Iruzubieta Source Type: research

Allergic Rhinitis in Children: An Underestimated Disease
This study aimed at determining the prevalence, sociodemographic features, comorbid illnesses, complications and quality of life in children referred to the outpatient clinic of “Allergic Rhinitis” in Penteli Children Hospital, Athens, Greece. We analyzed 590 pediatric patients referred to the outpatient clinic of “Allergic Rhinitis” in Penteli Children Hospital, Athens, Greece from 26/01/2012 to 20/11/2022. Allergic rhinitis was recorded as the one and only allergi c disease in 59% of the children diagnosed with allergic rhinitis, concomitant asthma in 16% of them, atopic dermatitis in 8% and allergic conjunctivit...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - December 13, 2023 Category: ENT & OMF Source Type: research

Persistent Hydrocephalus, Shunt, and Subglottic Stenosis in a Newborn with Plasminogen Deficiency due to Delayed Treatment with Plasminogen Concentrates: A Case Report
CONCLUSION: Plasminogen concentrates are critically needed in Europe and other parts of the world to improve the care of and prevent complications among patients with plasminogen deficiency.PMID:38043518 | DOI:10.1159/000534868 (Source: Neonatology)
Source: Neonatology - December 3, 2023 Category: Perinatology & Neonatology Authors: Benedikt Stephan Biesinger Christoph Male Veronika Kranebitter Julia Binder Martin B Niederle Andrea Reinprecht Christoph Binder Source Type: research

Congenital herpes simplex with ophthalmic and multisystem features: a case report
CONCLUSIONS: In the management of neonatal HSV, early diagnosis is essential for the timely initiation of antiviral therapy. Our report highlights that ocular assessment can be crucial in the correct diagnostic investigation of this condition.PMID:38044450 | DOI:10.1186/s12887-023-04423-1 (Source: Herpes)
Source: Herpes - December 3, 2023 Category: Infectious Diseases Authors: Samuel Montenegro Pereira Rian Vilar Lima Maria Carolina Rocha Muniz Marcus Breno Farias Ara újo Luiz de Moraes Ferreira J únior Juliana Tiburtino de Queiroz Sales Martins Cl áudia Faustino Coelho Luz David Ant ônio Camelo Cid Daniel da Rocha Lucena Source Type: research

Persistent Hydrocephalus, Shunt, and Subglottic Stenosis in a Newborn with Plasminogen Deficiency due to Delayed Treatment with Plasminogen Concentrates: A Case Report
CONCLUSION: Plasminogen concentrates are critically needed in Europe and other parts of the world to improve the care of and prevent complications among patients with plasminogen deficiency.PMID:38043518 | DOI:10.1159/000534868 (Source: Neonatology)
Source: Neonatology - December 3, 2023 Category: Perinatology & Neonatology Authors: Benedikt Stephan Biesinger Christoph Male Veronika Kranebitter Julia Binder Martin B Niederle Andrea Reinprecht Christoph Binder Source Type: research

Pathogen Surveillance for Acute Infectious Conjunctivitis
This cross-sectional study examines the microbial etiologies of acute infectious conjunctivitis at 4 sites in the US and 1 site in Israel. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research

Kawasaki Disease: Recent Diagnostics, Treatment, and Predictors for Treatment Failure and Coronary Artery Involvement
AbstractPurpose of ReviewKawasaki disease (KD) is a medium vessel vasculitis in pediatric patients with a predilection for coronary artery involvement. The disease can be complete or incomplete but generally consists of a fever longer than 5  days, bilateral conjunctivitis, rash, edema, cervical adenopathy, and mucosal involvement. Mainstay of therapy includes IV immunoglobulin and aspirin. The goal of this article is to identify recent research that focuses on the newest diagnostic tools, predictive factors for coronary involvement, a nd treatment failure, as well as the most recent literature on treatment.Recent Finding...
Source: Current Emergency and Hospital Medicine Reports - December 1, 2023 Category: Emergency Medicine Source Type: research