Comprehensive Profile of Pathogens and Antimicrobial Resistance in Conjunctivitis Cases from Niger
This study focuses on the pathogen and antimicrobial resistance (AMR) profiles identified in Niger. Sixty-two patients with acute infectious conjunctivitis who presented to health posts were enrolled from December 2021 to May 2022. Nasal and conjunctival swabs were obtained from each patient. Unbiased RNA deep sequencing (RNA-seq) was used to identify associated pathogens. A pathogen was identified in 39 patients (63%; 95% CI, 50-74). Of those, an RNA virus was detected in 23 patients (59%; 95% CI, 43-73). RNA viruses were diverse and included human coronaviruses (HCoVs): SARS-CoV-2, HCoV-229E, HCoV-HKU1, and HCoV-OC43. A ...
Source: The American Journal of Tropical Medicine and Hygiene - November 6, 2023 Category: Tropical Medicine Authors: Abdou Amza Beido Nassirou Boubacar Kadri Saley Ali Boubacar Mariama Ciss é Mamadou Ibrahim Lamine Aboubacar Roufaye Elodie Lebas Emily Colby Lina Zhong Cindi Chen Kevin Ruder Danny Yu YuHeng Liu Thomas Abraham Aaron Chang Lina Mai Armin Hinterwirth Geram Source Type: research
Comprehensive Profile of Pathogens and Antimicrobial Resistance in Conjunctivitis Cases from Niger
This study focuses on the pathogen and antimicrobial resistance (AMR) profiles identified in Niger. Sixty-two patients with acute infectious conjunctivitis who presented to health posts were enrolled from December 2021 to May 2022. Nasal and conjunctival swabs were obtained from each patient. Unbiased RNA deep sequencing (RNA-seq) was used to identify associated pathogens. A pathogen was identified in 39 patients (63%; 95% CI, 50-74). Of those, an RNA virus was detected in 23 patients (59%; 95% CI, 43-73). RNA viruses were diverse and included human coronaviruses (HCoVs): SARS-CoV-2, HCoV-229E, HCoV-HKU1, and HCoV-OC43. A ...
Source: Am J Trop Med Hyg - November 6, 2023 Category: Infectious Diseases Authors: Abdou Amza Beido Nassirou Boubacar Kadri Saley Ali Boubacar Mariama Ciss é Mamadou Ibrahim Lamine Aboubacar Roufaye Elodie Lebas Emily Colby Lina Zhong Cindi Chen Kevin Ruder Danny Yu YuHeng Liu Thomas Abraham Aaron Chang Lina Mai Armin Hinterwirth Geram Source Type: research
Comprehensive Profile of Pathogens and Antimicrobial Resistance in Conjunctivitis Cases from Niger
This study focuses on the pathogen and antimicrobial resistance (AMR) profiles identified in Niger. Sixty-two patients with acute infectious conjunctivitis who presented to health posts were enrolled from December 2021 to May 2022. Nasal and conjunctival swabs were obtained from each patient. Unbiased RNA deep sequencing (RNA-seq) was used to identify associated pathogens. A pathogen was identified in 39 patients (63%; 95% CI, 50-74). Of those, an RNA virus was detected in 23 patients (59%; 95% CI, 43-73). RNA viruses were diverse and included human coronaviruses (HCoVs): SARS-CoV-2, HCoV-229E, HCoV-HKU1, and HCoV-OC43. A ...
Source: The American Journal of Tropical Medicine and Hygiene - November 6, 2023 Category: Tropical Medicine Authors: Abdou Amza Beido Nassirou Boubacar Kadri Saley Ali Boubacar Mariama Ciss é Mamadou Ibrahim Lamine Aboubacar Roufaye Elodie Lebas Emily Colby Lina Zhong Cindi Chen Kevin Ruder Danny Yu YuHeng Liu Thomas Abraham Aaron Chang Lina Mai Armin Hinterwirth Geram Source Type: research
Comprehensive Profile of Pathogens and Antimicrobial Resistance in Conjunctivitis Cases from Niger
This study focuses on the pathogen and antimicrobial resistance (AMR) profiles identified in Niger. Sixty-two patients with acute infectious conjunctivitis who presented to health posts were enrolled from December 2021 to May 2022. Nasal and conjunctival swabs were obtained from each patient. Unbiased RNA deep sequencing (RNA-seq) was used to identify associated pathogens. A pathogen was identified in 39 patients (63%; 95% CI, 50-74). Of those, an RNA virus was detected in 23 patients (59%; 95% CI, 43-73). RNA viruses were diverse and included human coronaviruses (HCoVs): SARS-CoV-2, HCoV-229E, HCoV-HKU1, and HCoV-OC43. A ...
Source: Am J Trop Med Hyg - November 6, 2023 Category: Infectious Diseases Authors: Abdou Amza Beido Nassirou Boubacar Kadri Saley Ali Boubacar Mariama Ciss é Mamadou Ibrahim Lamine Aboubacar Roufaye Elodie Lebas Emily Colby Lina Zhong Cindi Chen Kevin Ruder Danny Yu YuHeng Liu Thomas Abraham Aaron Chang Lina Mai Armin Hinterwirth Geram Source Type: research
Comprehensive Profile of Pathogens and Antimicrobial Resistance in Conjunctivitis Cases from Niger
This study focuses on the pathogen and antimicrobial resistance (AMR) profiles identified in Niger. Sixty-two patients with acute infectious conjunctivitis who presented to health posts were enrolled from December 2021 to May 2022. Nasal and conjunctival swabs were obtained from each patient. Unbiased RNA deep sequencing (RNA-seq) was used to identify associated pathogens. A pathogen was identified in 39 patients (63%; 95% CI, 50-74). Of those, an RNA virus was detected in 23 patients (59%; 95% CI, 43-73). RNA viruses were diverse and included human coronaviruses (HCoVs): SARS-CoV-2, HCoV-229E, HCoV-HKU1, and HCoV-OC43. A ...
Source: The American Journal of Tropical Medicine and Hygiene - November 6, 2023 Category: Tropical Medicine Authors: Abdou Amza Beido Nassirou Boubacar Kadri Saley Ali Boubacar Mariama Ciss é Mamadou Ibrahim Lamine Aboubacar Roufaye Elodie Lebas Emily Colby Lina Zhong Cindi Chen Kevin Ruder Danny Yu YuHeng Liu Thomas Abraham Aaron Chang Lina Mai Armin Hinterwirth Geram Source Type: research
Comprehensive Profile of Pathogens and Antimicrobial Resistance in Conjunctivitis Cases from Niger
This study focuses on the pathogen and antimicrobial resistance (AMR) profiles identified in Niger. Sixty-two patients with acute infectious conjunctivitis who presented to health posts were enrolled from December 2021 to May 2022. Nasal and conjunctival swabs were obtained from each patient. Unbiased RNA deep sequencing (RNA-seq) was used to identify associated pathogens. A pathogen was identified in 39 patients (63%; 95% CI, 50-74). Of those, an RNA virus was detected in 23 patients (59%; 95% CI, 43-73). RNA viruses were diverse and included human coronaviruses (HCoVs): SARS-CoV-2, HCoV-229E, HCoV-HKU1, and HCoV-OC43. A ...
Source: Am J Trop Med Hyg - November 6, 2023 Category: Infectious Diseases Authors: Abdou Amza Beido Nassirou Boubacar Kadri Saley Ali Boubacar Mariama Ciss é Mamadou Ibrahim Lamine Aboubacar Roufaye Elodie Lebas Emily Colby Lina Zhong Cindi Chen Kevin Ruder Danny Yu YuHeng Liu Thomas Abraham Aaron Chang Lina Mai Armin Hinterwirth Geram Source Type: research
Ocular manifestations in COVID-19 infections: a case series
CONCLUSION: Ocular features are not infrequent in COVID-19 patients.PMID:37915673 | PMC:PMC10617833 | DOI:10.1097/MS9.0000000000001305 (Source: Annals of Medicine)
Source: Annals of Medicine - November 2, 2023 Category: Internal Medicine Authors: Naram Khalayli Ghina Haider Yara Hodifa Maysoun Kudsi Nada Naman Source Type: research
Dilemma in diagnosing incomplete Kawasaki disease in a resource limited setting
CONCLUSION: Diagnosis of KD in difficult in resource limited setting.PMID:37915681 | PMC:PMC10617906 | DOI:10.1097/MS9.0000000000001380 (Source: Annals of Medicine)
Source: Annals of Medicine - November 2, 2023 Category: Internal Medicine Authors: Mukesh Bhatta Aashish Baniya Diwakar Koirala Karun Bhattarai Abhishek Shah Source Type: research
Pathogen Surveillance for Acute Infectious Conjunctivitis
CONCLUSION AND RELEVANCE: In this cross-sectional study, pathogens associated with acute infectious conjunctivitis varied between all 5 sites in the US and Israel. Purulent discharge was a common presenting sign in this study, with a low specificity for bacteria-associated conjunctivitis, suggesting that further diagnostic workup may be necessary to inform antibiotic stewardship. Additional research on cost-effectiveness of using RNA deep sequencing is needed to ascertain whether it is better to monitor patients clinically until resolution of disease.PMID:37917077 | DOI:10.1001/jamaophthalmol.2023.4785 (Source: Herpes)
Source: Herpes - November 2, 2023 Category: Infectious Diseases Authors: Edmund Tsui Ruti Sella Vivien Tham Alan W Kong Esmeralda McClean Lee Goren Irit Bahar Nina Cherian Joana Ramirez Reginald E Hughes Joseph K Privratsky Tania Onclinx Rachel Feit-Leichman Angel Cheng Iliana Molina Phillip Kim Carol Yu Kevin Ruder Alexander Source Type: research
226 Dupilumab-associated head and neck dermatitis shows a pronounced type 22 immune signature mediated by oligoclonally expanded T cells
Dupilumab, a therapeutic antibody blocking the eczematous type 2 immune response in atopic dermatitis (AD), has shown efficacy in many clinical trials and real-world observational studies. In addition to blepharitis and conjunctivitis, the de novo appearance of head/neck dermatitis is now recognized as a distinct side effect, occurring in up to 10% of patients at any time after dupilumab initiation. Histopathological features distinct from conventional AD suggest a drug effect, but the exact underlying mechanisms remain unknown. (Source: Journal of Investigative Dermatology)
Source: Journal of Investigative Dermatology - November 1, 2023 Category: Dermatology Authors: C. Bangert, N. Alkon, S. Chennareddy, M. Pilz, J. Ruggiero, E. Cohenour, C. Jonak, J. Griss, P. Brunner Source Type: research
Clinical manifestations and risk factors of shock in children with multisystem inflammatory syndrome
CONCLUSIONS: MIS-C patients with high initial procalcitonin levels have higher risks of experiencing shock and may need ICU admission.PMID:37903693 | DOI:10.1016/j.jfma.2023.10.002 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - October 30, 2023 Category: General Medicine Authors: Chi-Hsien Wu Tu-Hsuan Chang Boon-Fatt Tan Jong-Lin Wu Song-Ming Huang Ting-Yu Yen En-Ting Wu Ching-Chia Wang Min-Tai Lin Chun-Yi Lu Luan-Yin Chang Li-Min Huang Source Type: research
Clinical manifestations and risk factors of shock in children with multisystem inflammatory syndrome
CONCLUSIONS: MIS-C patients with high initial procalcitonin levels have higher risks of experiencing shock and may need ICU admission.PMID:37903693 | DOI:10.1016/j.jfma.2023.10.002 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - October 30, 2023 Category: General Medicine Authors: Chi-Hsien Wu Tu-Hsuan Chang Boon-Fatt Tan Jong-Lin Wu Song-Ming Huang Ting-Yu Yen En-Ting Wu Ching-Chia Wang Min-Tai Lin Chun-Yi Lu Luan-Yin Chang Li-Min Huang Source Type: research
Exploration of efficacy and mechanism of 0.05% cyclosporine eye drops (II) monotherapy in allergic conjunctivitis-associated dry eye
Eye, Published online: 30 October 2023; doi:10.1038/s41433-023-02807-2Exploration of efficacy and mechanism of 0.05% cyclosporine eye drops (II) monotherapy in allergic conjunctivitis-associated dry eye (Source: Eye)
Source: Eye - October 30, 2023 Category: Opthalmology Authors: Xiting Jiao Yuanyuan Qi Ning Gao Chen Zhang Shaozhen Zhao Ruibo Yang Source Type: research
Allergic and immunopathological diseases of the ocular surface
Orv Hetil. 2023 Oct 29;164(43):1686-1692. doi: 10.1556/650.2023.32910. Print 2023 Oct 29.ABSTRACTAllergic and immunopathological diseases of the ocular surface are inflammations that can occur with mild to severe symptoms that cause visual impairment. Allergic inflammations mainly affect the conjunctiva, causing acute and/or chronic conjunctivitis. Several forms are distinguished: seasonal allergic conjunctivitis, vernal conjunctivitis, atopic keratoconjunctivitis, contact allergy, giant papillary conjunctivitis. The most common is the seasonal form, which is linked to seasons. Allergic ocular surface processes require loc...
Source: Orvosi Hetilap - October 29, 2023 Category: General Medicine Authors: L ászló Módis Ildik ó Süveges Source Type: research
Allergic and immunopathological diseases of the ocular surface
Orv Hetil. 2023 Oct 29;164(43):1686-1692. doi: 10.1556/650.2023.32910. Print 2023 Oct 29.ABSTRACTAllergic and immunopathological diseases of the ocular surface are inflammations that can occur with mild to severe symptoms that cause visual impairment. Allergic inflammations mainly affect the conjunctiva, causing acute and/or chronic conjunctivitis. Several forms are distinguished: seasonal allergic conjunctivitis, vernal conjunctivitis, atopic keratoconjunctivitis, contact allergy, giant papillary conjunctivitis. The most common is the seasonal form, which is linked to seasons. Allergic ocular surface processes require loc...
Source: Orvosi Hetilap - October 29, 2023 Category: General Medicine Authors: L ászló Módis Ildik ó Süveges Source Type: research
