Reply to letter to the editor: Kawasaki disease and COVID-19: A pretext for a hot topic.
PMID: 33431260 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 8, 2021 Category: General Medicine Authors: Chen YC, Cao Q, Chen CL, Chiu CH Tags: J Formos Med Assoc Source Type: research

Charlson comorbidity index predicts outcomes of elderly after allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia and myelodysplastic syndrome.
CONCLUSION: This cohort study suggests that CCI ≥3 predicts poor outcomes, primarily due to a higher NRM risk. Careful management of GVHD after transplantation could improve outcomes in elderly patients with AML or MDS after allo-HSCT. PMID: 33423899 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 8, 2021 Category: General Medicine Authors: Chien SH, Yao M, Li CC, Chang PY, Yu MS, Huang CE, Tan TD, Lin CH, Yeh SP, Li SS, Wang PN, Liu YC, Gau JP Tags: J Formos Med Assoc Source Type: research

Flat foot and spinal degeneration: Evidence from nationwide population-based cohort study.
CONCLUSION: Flat foot was found to be an independent risk factor for subsequent spinal DJD. PMID: 33423898 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 7, 2021 Category: General Medicine Authors: Chou MC, Huang JY, Hung YM, Perng WT, Chang R, Wei JC Tags: J Formos Med Assoc Source Type: research

Sex, racial differences and healthy aging in normative reference ranges on diastolic function in Ethnic Asians: 2016 ASE guideline revisited.
Abstract BACKGROUND: Diastolic dysfunction (DD) has shown to be a hallmark pathological intermediate in the development of heart failure with preserved ejection fraction (HFpEF). We aim to establish age- and sex-stratified normal reference values of diastolic indices and to explore racial-differences. METHODS: We explored age- and sex-related structural/functional alterations from 6023 healthy ethnic Asians (47.1 ± 10.9 years, 61.3% men) according to 2016 American Society of Echocardiography (ASE) diastolic dysfunction (DD) criteria. Racial comparisons were made using data from London Life Sc...
Source: J Formos Med Assoc - January 7, 2021 Category: General Medicine Authors: Chang SN, Sung KT, Huang WH, Lin JW, Chien SC, Hung TC, Su CH, Hung CL, Tsai CT, Wu YW, Chiang FT, Yeh HI, Hwang JJ Tags: J Formos Med Assoc Source Type: research

Real-world evidence of the safety and effectiveness of regorafenib in Taiwanese patients with metastatic colorectal cancer: CORRELATE Taiwan.
CONCLUSIONS: The safety and effectiveness of regorafenib in this real-world study was generally consistent with the known efficacy and safety profile in Asian patients in clinical trials. TRIAL REGISTRATION: NCT02042144. PMID: 33422398 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 6, 2021 Category: General Medicine Authors: Yeh KH, Yang TS, Hsu TC, Tzu-Liang Chen W, Chen HH, Teng HW, Lin BW, Kuan FC, Chiang FF, Duann CW, Li YS, Lin MT, Fiala-Buskies S, Ducreux M, Wang JY Tags: J Formos Med Assoc Source Type: research

Alkaline substances gastroesophageal injury in young children: emphasis on Asian food preparation habits.
CONCLUSION: Alkaline ingestion usually results in esophageal injury that is difficult to cure. Corrosive esophageal strictures cause swallowing difficulties and growth stunting in children. Young children who ingested alkaline oil have more complications. Given that alkaline corrosive injuries are often accidental, prevention of corrosive agent ingestion is crucial. PMID: 33422399 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 6, 2021 Category: General Medicine Authors: Chen CC, Chen AC, Wu SF Tags: J Formos Med Assoc Source Type: research

The severity of visual field defect and the defective angles of localized retinal nerve fiber layer using a novel approach.
CONCLUSION: Our novel method was more convenient in a clinical setting and noninferior to the original method. PMID: 33422400 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 6, 2021 Category: General Medicine Authors: Chen A, Cheng YC, Lai HY, Lin PW, Wu PC, Kuo MT, Lai IC Tags: J Formos Med Assoc Source Type: research

Reply to "Tacrolimus concentrations were not affected by glecaprevir/pibrentasvir treatment for hepatitis C virus infection in an adult living donor liver transplant recipient with uremia".
Reply to "Tacrolimus concentrations were not affected by glecaprevir/pibrentasvir treatment for hepatitis C virus infection in an adult living donor liver transplant recipient with uremia". J Formos Med Assoc. 2021 Jan 06;: Authors: Yu ML, Kao JH PMID: 33422401 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 6, 2021 Category: General Medicine Authors: Yu ML, Kao JH Tags: J Formos Med Assoc Source Type: research

Successful treatment of 28 patients with coronavirus disease 2019 at a medical center in Taiwan.
We present the clinical characteristics and outcomes of 28 COVID-19 patients treated in our hospital in Taiwan. METHODS: Patients with COVID-19, confirmed by positive real-time reverse-transcriptase polymerase chain reaction results for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral nucleic acids from oropharyngeal swab specimens between February 4, 2020 and July 6, 2020, were enrolled. Their clinical characteristics and outcomes were reviewed. RESULTS: Seventeen of the 28 patients (60.7%) had pneumonia. The most frequent symptoms were cough (n = 23, 82.1%) and fever (n = 1...
Source: J Formos Med Assoc - December 30, 2020 Category: General Medicine Authors: Tsai CC, Wang YC, Chiang TT, Chen IA, Chiu CH, Yang YS, Yeh KM, Chang FY Tags: J Formos Med Assoc Source Type: research

Trends in adaptation of fifteen European countries population to SARS-CoV-2 in March-May 2020: Can Taiwanese experience be adopted?
CONCLUSION: In case of a second wave of COVID-19 disease in Europe, it will coincide with seasonal common cold surge, spanning from mid-September 2020 to mid-February 2021, with a median in November-December 2020. Strict epidemiological surveillance must be observed in Europe at that time. PMID: 32798031 [PubMed - in process] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 30, 2020 Category: General Medicine Authors: Sharov KS Tags: J Formos Med Assoc Source Type: research

Dysosmia and dysgeusia in patients with COVID-19 in northern Taiwan.
Abstract BACKGROUND/PURPOSE: To investigate the characteristics of dysosmia and dysgeusia among patients diagnosed with coronavirus disease 2019 (COVID-19) in Taiwan. METHODS: Prospective data collection between January 22, 2020 to May 7, 2020 of nucleic acid confirmed COVID-19 hospitalized patients in northern Taiwan by the Taiwan Centers for Disease Control were analyzed. RESULTS: Of 217 patients enrolled, 78 (35.9%) reported dysosmia (n = 73, 33.6%) and/or dysgeusia (n = 62, 28.6%). The median duration of COVID-19 associated symptom-onset to development of dysosmia and/or dysgeusia was
Source: J Formos Med Assoc - December 30, 2020 Category: General Medicine Authors: Sheng WH, Liu WD, Wang JT, Chang SY, Chang SC Tags: J Formos Med Assoc Source Type: research

Rehabilitation programs for patients with COronaVIrus Disease 2019: consensus statements of Taiwan Academy of Cardiovascular and Pulmonary Rehabilitation.
Abstract The COronaVIrus Disease 2019 (COVID-19), which developed into a pandemic in 2020, has become a major healthcare challenge for governments and healthcare workers worldwide. Despite several medical treatment protocols having been established, a comprehensive rehabilitation program that can promote functional recovery is still frequently ignored. An online consensus meeting of an expert panel comprising members of the Taiwan Academy of Cardiovascular and Pulmonary Rehabilitation was held to provide recommendations for rehabilitation protocols in each of the five COVID-19 stages, namely (1) outpatients with m...
Source: J Formos Med Assoc - December 16, 2020 Category: General Medicine Authors: Cheng YY, Chen CM, Huang WC, Chiang SL, Hsieh PC, Lin KL, Chen YJ, Fu TC, Huang SC, Chen SY, Chen CH, Chen SM, Chen HS, Chou LW, Chou CL, Li MH, Tsai SW, Wang LY, Wang YL, Chou W Tags: J Formos Med Assoc Source Type: research

Comparison of clinicopathological features and treatment outcomes in aggressive primary intestinal B- and T/NK-cell lymphomas.
Abstract BACKGROUND: Primary intestinal lymphomas (PILs) are rare, and this study compared the clinical outcomes of aggressive primary intestinal B-cell lymphomas (aB-PILs) and T/natural killer-cell lymphomas (T/NK-PILs). METHODS: The clinical information of patients diagnosed with aggressive PILs at our institution between 1995 and 2015 were retrospectively investigated. Pathological subtypes were confirmed according to the 2016 revision of the World Health Organization classification. The correlation between clinicopathological features and overall survival (OS) was determined using univariate and multivari...
Source: J Formos Med Assoc - December 10, 2020 Category: General Medicine Authors: Ma WL, Yeh KH, Yao M, Tang JL, Lin CW, Wang YT, Yeh YC, Wang HP, Cheng AL, Kuo SH Tags: J Formos Med Assoc Source Type: research

Corrigendum to "Biomechanical effect of implant design on four implants supporting mandibular full-arch fixed dentures: in  vitro test and finite element analysis" [Journal of the Formosan Medical Association 119 (2020) 1514-1523].
Corrigendum to "Biomechanical effect of implant design on four implants supporting mandibular full-arch fixed dentures: in vitro test and finite element analysis" [Journal of the Formosan Medical Association 119 (2020) 1514-1523]. J Formos Med Assoc. 2021 Jan;120(1 Pt 2):567 Authors: Yu-Jen Wu A, Hsu JT, Fuh LJ, Huang HL PMID: 33276908 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 7, 2020 Category: General Medicine Authors: Yu-Jen Wu A, Hsu JT, Fuh LJ, Huang HL Tags: J Formos Med Assoc Source Type: research

Factors related to preventive COVID-19 infection behaviors among people with mental illness.
CONCLUSION: Based on the results, healthcare providers should help individuals with mental illness reduce self-stigma and fear of COVID-19 which would consequently improve their preventive COVID-19 infection behaviors. Moreover, improving trust in COVID-19 information sources for individuals with mental illness may be another method to improve their preventive behaviors. PMID: 32773260 [PubMed - indexed for MEDLINE] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 1, 2020 Category: General Medicine Authors: Chang KC, Strong C, Pakpour AH, Griffiths MD, Lin CY Tags: J Formos Med Assoc Source Type: research

High rates of misidentification of uncommon Candida species causing bloodstream infections using conventional phenotypic methods.
CONCLUSION: Misidentification of uncommon Candida species was common using the conventional methods, especially for C. sake and C. famata. MALDI-TOF MS assisted by DNA-sequencing methods should be considered. PMID: 33250336 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 27, 2020 Category: General Medicine Authors: Huang YS, Wang FD, Chen YC, Huang YT, Hsieh MH, Hii IM, Lee YL, Ho MW, Liu CE, Chen YH, Liu WL Tags: J Formos Med Assoc Source Type: research

The role of ventilation in tuberculosis control.
PMID: 33246741 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 24, 2020 Category: General Medicine Authors: Chan PC, Fang CT Tags: J Formos Med Assoc Source Type: research

The clinical features of endoscopic treated isolated sphenoid sinus diseases.
CONCLUSION: ISSD represents a variety of etiologies, mostly comprising fungal ball in our area, while there is still a considerable proportion of ISSDs attributed to neoplasm and CSF leak. Untreated ISSD can result in serious complications. We recommend early surgical intervention for all patients with ISSD. PMID: 33246742 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 24, 2020 Category: General Medicine Authors: Chao CC, Lin YT, Lin CF, Chiang CW, Lin HC, Yeh TH Tags: J Formos Med Assoc Source Type: research

LncRNA NRON promotes M2 macrophage polarization and alleviates atrial fibrosis through suppressing exosomal miR-23a derived from atrial myocytes.
CONCLUSION: NRON promotes M2 macrophage polarization and alleviates atrial fibrosis through suppressing exosomal miR-23a derived from atrial myocytes. PMID: 33246743 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 24, 2020 Category: General Medicine Authors: Li J, Zhang Q, Jiao H Tags: J Formos Med Assoc Source Type: research

Characteristics of tear film lipid layer in young dry eye patients.
Abstract BACKGROUND/PURPOSE: To investigate the characteristics of subjective symptoms and objective parameters among young patients with dry eye disease (DED) and compare them with those of older patients. METHODS: We retrospectively enrolled 675 patients with DED who were divided into three age groups (20-41 years [younger], 41-60 years [middle], and>60 years [older]) (n = 143, 304, and 228, respectively). Subjective symptoms were evaluated using Standardized Patient Evaluation of Eye Dryness (SPEED) and Ocular Surface Disease Index (OSDI) questionnaires. Aqueous tear secretion was evaluated wi...
Source: J Formos Med Assoc - November 23, 2020 Category: General Medicine Authors: Weng HY, Ho WT, Chiu CY, Tsai TY, Chang SW Tags: J Formos Med Assoc Source Type: research

Barriers to bystanders defibrillation: A national survey on public awareness and willingness of bystanders defibrillation ☆.
CONCLUSION: The importance of active awareness and the barriers to the use of AEDs among bystanders seemed to have been underestimated in the past years. The relatively low willingness to use AEDs among bystander healthcare providers and women needs further investigation. PMID: 33218851 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 17, 2020 Category: General Medicine Authors: Pei-Chuan Huang E, Chiang WC, Lu TC, Wang CH, Sun JT, Hsieh MJ, Wang HC, Yang CW, Lin CH, Lin JJ, Yang MC, Huei-Ming Ma M Tags: J Formos Med Assoc Source Type: research

Outcomes and prognostic factors associated with 180-day mortality in Taiwanese pediatric patients with Hemophagocytic Lymphohistiocytosis.
CONCLUSION: The overall outcome in our cohort was similar to that reported in some of the largest international cohorts. Hypertriglyceridemia and anemia may be indicative of poor prognoses in pediatric HLH patients independently and may be used to guide treatment strategy formulations for better outcomes. PMID: 33218852 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 17, 2020 Category: General Medicine Authors: Yu TY, Lu MY, Lin KH, Chang HH, Chou SW, Lin DT, Jou ST, Yang YL Tags: J Formos Med Assoc Source Type: research

Quantitative analysis of intraoperative electrocorticography mirrors histopathology and seizure outcome after epileptic surgery in children.
CONCLUSION: Our results suggested that quantification of intraoperative ECoG predicted seizure outcomes and reflected different ED pattern and frequencies between MCD and non-dysplastic histopathology among children who underwent resective epileptic surgery. The results of our study were encouraging and indicated that intraoperative ECoG improved the outcomes of surgery in children with epilepsy. PMID: 33214033 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 17, 2020 Category: General Medicine Authors: Peng SJ, Wong TT, Huang CC, Chang H, Hsieh KL, Tsai ML, Yang YS, Chen CL Tags: J Formos Med Assoc Source Type: research

Management consensus guideline for hepatocellular carcinoma: 2020 update on surveillance, diagnosis, and systemic treatment by the Taiwan Liver Cancer Association and the Gastroenterological Society of Taiwan.
Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality in Taiwan. The Taiwan Liver Cancer Association and the Gastroenterological Society of Taiwan had established a management consensus guideline in 2016. The current recommendations focus on updating critical issues regarding the management of HCC, including surveillance, diagnosis, and systemic treatment. For surveillance, the updated guideline suggests the role of dynamic computed tomography or magnetic resonance imaging and contrast-enhanced ultrasound (CEUS) in selected patients. For diagnosis, this update incorporates CEUS and...
Source: J Formos Med Assoc - November 13, 2020 Category: General Medicine Authors: Shao YY, Wang SY, Lin SM, Diagnosis Group,, Systemic Therapy Group Tags: J Formos Med Assoc Source Type: research

Changes of serum pepsinogen level and ABC classification after bariatric surgery.
Abstract BACKGROUND: Very few studies have explored the changes of serum pepsinogen after bariatric surgery and no research has evaluated the feasibility of ABC classification to predict gastric cancer risk after bariatric surgery. METHODS: We enrolled 94 obese subjects that received bariatric surgery, including 41 sleeve gastrectomy (SG) and 53 Roux-en-Y gastric bypass (RYGB). The serum pepsinogen I (PGI), pepsinogen II (PGII), PGI/II ratio and seropositivity of Helicobacter pylori ( H. pylori ) were measured before and one year after surgery. Patients were classified according to ABC classification and post...
Source: J Formos Med Assoc - November 13, 2020 Category: General Medicine Authors: Han ML, Liou JM, Ser KH, Chen JC, Chen SC, Lee WJ Tags: J Formos Med Assoc Source Type: research

Poor mental health among Taiwanese people experiencing the public debates on and referendums for same-sex marriage: A Facebook online survey.
CONCLUSION: The rates of poor mental health status increased in both heterosexual and nonheterosexual people during the period of public debates on and the referendums for same-sex marriage. Heterosexual people who were female, were young, and supported same-sex marriage had also increased rates of poor mental health state during the same period. PMID: 33189505 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 12, 2020 Category: General Medicine Authors: Chen MH, Ko NY, Huang YT, Hu HF, Lu WH, Yen CF Tags: J Formos Med Assoc Source Type: research

Chikungunya infection: First autochthonous cases in Taiwan.
Abstract The first autochthonous case and the first outbreak of chikungunya in Taiwan occurred during July-October 2019, with a total of 21 cases confirmed. Genetic analysis revealed the strains belonged to East/Central/South African genotype and had 99.95%-100% identity with the strains from the imported cases from Myanmar in 2019. This event confirmed that the imported chikungunya cases has the potential to cause autochthonous transmission in Taiwan; intensified surveillance and vector control measures are essential to contain the outbreak. PMID: 33191091 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 12, 2020 Category: General Medicine Authors: Chen MY, Huang AS, Yang CF, Hsu TC, Wang TC, Su CL, Chang MC, Peng SH, Shu PY Tags: J Formos Med Assoc Source Type: research

Orbital exenteration: A 20-year experience from a tertiary center in Taiwan.
CONCLUSION: We found worse prognosis with positive lymphovascular invasion. Although not significant, malignant melanoma showed poorer survival times compared to sebaceous gland carcinoma. Close follow-up, especially in the first 2 years after orbital exenteration, is crucial to identify disease recurrence. PMID: 33191092 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 12, 2020 Category: General Medicine Authors: Wang WY, Liao SL, Wei YH Tags: J Formos Med Assoc Source Type: research

Preclinical evaluation of a 3D-printed hydroxyapatite/poly(lactic-co-glycolic acid) scaffold for ridge augmentation.
CONCLUSION: The 3DP HA/PLGA scaffold maintains supracrestal space and demonstrates osteoconductivity to facilitate SRA. PMID: 33191094 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 12, 2020 Category: General Medicine Authors: Chang PC, Luo HT, Lin ZJ, Tai WC, Chang CH, Chang YC, Cochran DL, Chen MH Tags: J Formos Med Assoc Source Type: research

Arecoline enhances miR-21 to promote buccal mucosal fibroblasts activation.
CONCLUSION: MiR-21 overexpression in OSF may be due to the stimulation of areca nut, which was mediated by the TGF-β pathway. Our data suggested that the repression of miR-21 was a promising direction to palliate the development and progression of OSF. PMID: 33191095 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 12, 2020 Category: General Medicine Authors: Yang HW, Yu CC, Hsieh PL, Liao YW, Chu PM, Yu CH, Fang CY Tags: J Formos Med Assoc Source Type: research

Endovascular management of aorto-iliac occlusive disease (Leriche syndrome).
CONCLUSION: Endovascular therapy for chronic aorto-iliac occlusion has a high technical success rate, with good short- and mid-term primary and secondary patency rates and may provide a valid alternative to surgery for high-risk patients. PMID: 33189506 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 11, 2020 Category: General Medicine Authors: Liang HL, Li MF, Hsiao CC, Wu CJ, Wu TH Tags: J Formos Med Assoc Source Type: research

Efficacy of gabexate mesilate in preventing post endoscopic retrograde cholangiopancreatography pancreatitis: A meta-analysis of randomized clinical trials.
CONCLUSION: The present synthesis found that gabexate mesilate could be an option of prophylactic treatment of pancreatitis for patients undergoing ERCP, and reveals that it is favorable to administer it starting 30 min before the ERCP. This evidence may improve the clinical prevention of PEP. PMID: 33183879 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 9, 2020 Category: General Medicine Authors: Chiu YJ, Chen SC, Kang YN, Hou SK, Chao CC, Chang CC Tags: J Formos Med Assoc Source Type: research

Comparison of regular- and slope-configured dental implants placed in the edentulous ridge with height discrepancy: A pilot randomized controlled trial.
CONCLUSION: Slope-configured implants maintained the implant-supporting structures and minimally altered periodontal status of the adjacent teeth in RHDs. PMID: 33162294 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 5, 2020 Category: General Medicine Authors: Tu CC, Wang SH, Hu CY, Chen MH, Hsieh O, Chang PC Tags: J Formos Med Assoc Source Type: research

Montelukast does not increase the risk of attention-deficit/hyperactivity disorder in pediatric asthma patients: A nationwide population-based matched cohort study.
CONCLUSION: This nationwide population-based cohort study reveals that asthma children treated with montelukast were not at an increased risk of developing ADHD. Nevertheless, validation of our retrospective survey requires further prospective study. PMID: 33158697 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 3, 2020 Category: General Medicine Authors: Huang PY, Yang YH, Huang YH, Kuo HC, Wang LJ, Chien SJ, Chang LS Tags: J Formos Med Assoc Source Type: research

Prognostic markers in patients undergoing transcatheter implantation of Venus P-valve: Experience in Taiwan.
Abstract BACKGROUND/PURPOSE: Prognostic factors remain unclear in patients undergoing transcatheter implantation of Venus P-valve for their severe pulmonary regurgitation associated with native right ventricular (RV) outflow tract. METHOD: Between January 2017 and October 2018, we prospectively collected data of patient characteristics, cardiac magnetic resonance imaging, cardiopulmonary exercise testing, and levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP) before and 6-12 months after valve graft implantation. RESULTS: Fifteen patients (male: 8, median age: 24.8 years) were enrolled. The ...
Source: J Formos Med Assoc - November 3, 2020 Category: General Medicine Authors: Lin MT, Chen CA, Chen SJ, Chiu SN, Lu CW, Wu MH, Wang JK Tags: J Formos Med Assoc Source Type: research

A 45-year experience of uveal melanoma in Taiwan: Verification of American Joint Committee on Cancer staging system and prognostic factors.
CONCLUSION: The AJCC 8th edition prognostic staging groups for outcome prediction was validated. Periodic screening for metastases should be more frequent in the first five-year follow-up. The tumors with epithelioid cell pattern and ciliary body involvements were at risk of higher tumor-related mortality in Taiwanese patients. PMID: 33127270 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - October 27, 2020 Category: General Medicine Authors: Ma ST, Hsieh YT, Wei YH, Liao SL Tags: J Formos Med Assoc Source Type: research

Cytomegalovirus colitis with presentation of hemorrhagic colitis in chronic myeloid leukemia during dasatinib therapy.
PMID: 33127271 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - October 27, 2020 Category: General Medicine Authors: Chuang TM, Hsu CM, Liang PI, Hsiao HH Tags: J Formos Med Assoc Source Type: research

First case report of persistent Streptococcus mitis bacteremia caused by prosthesis-induced esophageal rupture.
PMID: 33127272 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - October 27, 2020 Category: General Medicine Authors: Huang RC, Chiang TT, Chiang MH, Yang YS Tags: J Formos Med Assoc Source Type: research

Serial cardiopulmonary exercise testing in an asymptomatic young female receiving percutaneous balloon dilatation for cor triatriatum sinistrum at an early age.
Abstract A young female was diagnosed as classic cor triatriatum sinistrum (CTS) at 38 months old incidentally and she received percutaneous catheter-based balloon dilatation twice at 41 and 48 months old. She took regular follow-up by echocardiography biannually with no re-stenosis of the orifice in the membrane between two chambers in the left atrium and she denied any cardiac-related symptoms. Serial cardiopulmonary exercise testing (CPET) by treadmill under Ramped-Bruce protocol was done at her 13, 19, and 23-year old. She could reach maximal effort and complete the three CPETs. No significant change of metabo...
Source: J Formos Med Assoc - October 27, 2020 Category: General Medicine Authors: Tuan SH, Chen GB, Chen CH, Liou I, Sun SF, Wu SY, Lin KL Tags: J Formos Med Assoc Source Type: research

Aspergillus terreus septic arthritis and pyomyositis of shoulder.
PMID: 33115625 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - October 25, 2020 Category: General Medicine Authors: Liu JW, Liu PY, Lai KL Tags: J Formos Med Assoc Source Type: research

Role of hepatitis D virus in persistent alanine aminotransferase abnormality among chronic hepatitis B patients treated with nucleotide/nucleoside analogues.
Abstract BACKGROUND: The biochemical response is a crucial indicator of prognosis in chronic hepatitis B (CHB) patients treated with nucleotide/nucleoside analogues (NAs). The impact of hepatitis D virus (HDV) infection on alanine aminotransferase normalization is elusive. METHODS: The longitudinal study recruited 1185 CHB patients who received NAs. These patients were tested for anti-HDV antibody and HDV RNA at the initiation of anti-hepatitis B virus (HBV) therapy and annually for patients who were HDV-seropositive. ALT levels were examined at the first and second year of anti-HBV therapy. ALT abnormality w...
Source: J Formos Med Assoc - October 24, 2020 Category: General Medicine Authors: Jang TY, Wei YJ, Yeh ML, Liu SF, Hsu CT, Hsu PY, Liu TW, Lin YH, Liang PC, Hsieh MH, Ko YM, Tsai YS, Chen KY, Lin CC, Tsai PC, Wang SC, Huang CI, Lin ZY, Chen SC, Chuang WL, Huang JF, Dai CY, Huang CF, Yu ML Tags: J Formos Med Assoc Source Type: research

Ropeginterferon Alfa-2b administered every two weeks for patients with genotype 2 chronic hepatitis C.
CONCLUSION: Ropeginterferon alfa-2b, although at only half the number of injections, is as safe and effective as Peg-IFN-α2a for genotype 2 CHC. A phase 3 study to confirm safety and efficacy of Ropeginterferon alfa-2b in genotype 2 CHC is ongoing. PMID: 33077341 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - October 16, 2020 Category: General Medicine Authors: Hsu SJ, Yu ML, Su CW, Peng CY, Chien RN, Lin HH, Lo GH, Su WW, Kuo HT, Hsu CW, Yang SS, Yang SS, Tseng KC, Qin A, Huang YW, Chuang WL Tags: J Formos Med Assoc Source Type: research

A prediction model for patients with emergency medical service witnessed out-of-hospital cardiac arrest.
Abstract BACKGROUND/PURPOSE: The study aim was to develop a model for predicting patients with emergency medical service (EMS) witnessed out-of-hospital cardiac arrest (OHCA). METHODS: We used fire-based EMS data from Taipei city to develop the prediction model. Patients included in this study were those who were initially alive, non-traumatic, and age ≧20 years. Data were extracted from electronic records of ambulance run sheets and an Utstein-style OHCA registry. The primary outcome (EMS-witnessed OHCA) was defined as cardiac arrest occurring during the service of emergency medical technicians before arri...
Source: J Formos Med Assoc - October 13, 2020 Category: General Medicine Authors: Hsieh MJ, Chiang WC, Sun JT, Chang WT, Chien YC, Wang YC, Huei-Ming Ma M Tags: J Formos Med Assoc Source Type: research

Quality of life with pregnancy outcomes: Further evaluating item properties for refined Taiwan's FertiQoL.
CONCLUSIONS: The study results demonstrate that the refined Taiwan's FertiQoL is valid and reliable, suggesting that this FertiQoL should refined to be culturally and language appropriate for Taiwanese population. PMID: 33060008 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - October 12, 2020 Category: General Medicine Authors: Wu MH, Chong KS, Huey NG, Ou HT, Lin CY Tags: J Formos Med Assoc Source Type: research

Retrospective evaluation of gingival thickness and tissue stability after connective tissue grafting in Asian populations: 1 month to 3.5 years.
The objectives of this retrospective study are to analyze post-surgical gingival thickness after connective tissue grafting in the Asian population and to assess its tissue stability for up to approximately 3.5 years. METHODS: A total of 111 grafted teeth and 57 nearby nongrafted teeth in 28 Asian patients who had undergone connective tissue grafting surgery were selected. Gingival thickness was measured by transgingival probing. The mean gingival thickness of the grafted teeth was compared with adjacent nongrafted teeth in the same individuals. The mean gingival thickness of the grafted teeth in different tooth types...
Source: J Formos Med Assoc - October 12, 2020 Category: General Medicine Authors: Lin IP, Lai EH, Lai CL, Su FY Tags: J Formos Med Assoc Source Type: research

An introduction to gender issue discussion platform in medical hygiene policies.
PMID: 33036829 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - October 6, 2020 Category: General Medicine Authors: Wang LJ, Wang LH, Sung TH, Wei SL Tags: J Formos Med Assoc Source Type: research

Efficacy and safety of balloon pulmonary angioplasty in patients with inoperable chronic thromboembolic pulmonary hypertension.
In this study, we evaluated the effects of BPA on clinical parameters including hemodynamics, echocardiography and functional status in patients with inoperable CTEPH in Taiwan. METHODS: We retrospectively collected the clinical data of inoperable CTEPH patients who underwent ≥3 BPA sessions. Pulmonary hemodynamic parameters of right heart catheterization, echocardiography, 6-min walk distance and World Health Organization (WHO) functional class were collected and analyzed before and after BPA treatment. RESULTS: A total of 59 BPA sessions were performed in 13 inoperable CTEPH patients. No periprocedural death...
Source: J Formos Med Assoc - October 5, 2020 Category: General Medicine Authors: Chen ZW, Wu CK, Kuo PH, Hsu HH, Tsai CH, Pan CT, Hwang JJ, Ko CL, Huang YS, Ogo T, Lin YH Tags: J Formos Med Assoc Source Type: research

Metronomic chemotherapy with tegafur-uracil following radical resection in stage II colorectal cancer.
Abstract BACKGROUND: Stage II colorectal cancer has a relatively good prognosis. Adjuvant chemotherapy following surgery is the standard treatment for stage III colorectal cancer but is not routinely recommended for all stage II colorectal cancer patients. We aimed to evaluate the clinical outcomes, treatment results, and prognostic factors in stage II colorectal cancer patients who underwent curative surgery with/without oral tegafur-uracil (UFT). METHODS: We included stage II colorectal cancer patients who underwent curative surgery and were followed up for at least 5 years after surgery at the National Tai...
Source: J Formos Med Assoc - October 2, 2020 Category: General Medicine Authors: Chen TC, Jeng YM, Liang JT Tags: J Formos Med Assoc Source Type: research

Depression and recovery of IL-17A secretion in mitogen responses in patients with active tuberculosis-a prospective observational study.
CONCLUSIONS: The non-TB-specific IL-17A secretions were lower in active TB patients upon TB diagnosis and associated with higher disease severity and worse treatment outcomes. Trend of recovery of the depressed Th17-related cytokines was noted after effective anti-TB treatment. PMID: 33020006 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - October 1, 2020 Category: General Medicine Authors: Feng JY, Ho LI, Chuang FY, Pan SW, Chen YY, Tung CL, Li CP, Su WJ Tags: J Formos Med Assoc Source Type: research

LncRNA MEG3 inhibits self-renewal and invasion abilities of oral cancer stem cells by sponging miR-421.
CONCLUSION: Our findings suggest that MEG3 can serve as a tumor suppressor in oral CSCs by impeding the action of miR-421. Moreover, targeting MEG3-miR-421 axis has the potential to mitigate the tumor recurrence and metastasis. PMID: 33012637 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - October 1, 2020 Category: General Medicine Authors: Chen PY, Hsieh PL, Peng CY, Liao YW, Yu CH, Yu CC Tags: J Formos Med Assoc Source Type: research