SARS-CoV-2 seroprevalence among blood donors, Chongqing, China, January 1 to May 31, 2020
J Formos Med Assoc. 2022 Jan 10:S0929-6646(22)00004-3. doi: 10.1016/j.jfma.2022.01.004. Online ahead of print.NO ABSTRACTPMID:35042626 | PMC:PMC8743574 | DOI:10.1016/j.jfma.2022.01.004 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 19, 2022 Category: General Medicine Authors: Shichun Wang Min Song Qi Liu Chunyan Yao Source Type: research

SARS-CoV-2 seroprevalence among blood donors, Chongqing, China, January 1 to May 31, 2020
J Formos Med Assoc. 2022 Jan 10:S0929-6646(22)00004-3. doi: 10.1016/j.jfma.2022.01.004. Online ahead of print.NO ABSTRACTPMID:35042626 | PMC:PMC8743574 | DOI:10.1016/j.jfma.2022.01.004 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 19, 2022 Category: General Medicine Authors: Shichun Wang Min Song Qi Liu Chunyan Yao Source Type: research

SARS-CoV-2 seroprevalence among blood donors, Chongqing, China, January 1 to May 31, 2020
J Formos Med Assoc. 2022 Jan 10:S0929-6646(22)00004-3. doi: 10.1016/j.jfma.2022.01.004. Online ahead of print.NO ABSTRACTPMID:35042626 | DOI:10.1016/j.jfma.2022.01.004 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 19, 2022 Category: General Medicine Authors: Shichun Wang Min Song Qi Liu Chunyan Yao Source Type: research

Healthy Taiwan-- an illusion of progress or an achievable vision?
J Formos Med Assoc. 2022 Jan 15:S0929-6646(21)00598-2. doi: 10.1016/j.jfma.2021.12.031. Online ahead of print.NO ABSTRACTPMID:35039201 | DOI:10.1016/j.jfma.2021.12.031 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 18, 2022 Category: General Medicine Authors: Chia-Hsiu Liu Shu-Ying Luo Hsien-Wen Kuo Source Type: research

Predictors of changes in preoperative tumor stage between dynamic computed tomography and gadoxetate disodium-enhanced magnetic resonance imaging for hepatocellular carcinoma
J Formos Med Assoc. 2022 Jan 12:S0929-6646(21)00593-3. doi: 10.1016/j.jfma.2021.12.026. Online ahead of print.ABSTRACTBACKGROUND/PURPOSE: Gadoxetate disodium-enhanced magnetic resonance imaging (EOB-MRI) has a higher diagnostic accuracy for hepatocellular carcinoma (HCC) than computed tomography (CT). However, indications for performing EOB-MRI after dynamic CT are not well defined. Therefore, we investigated the clinical factors associated with changes in the preoperative tumor stage between dynamic CT and EOB-MRI.METHODS: A prospective cohort was conducted from January 2014 to December 2017. 156 adult patients with clini...
Source: J Formos Med Assoc - January 16, 2022 Category: General Medicine Authors: Chih-Horng Wu Yu-Hsin Lee Po-Chin Liang Rey-Heng Hu Tiffany Ting-Fang Shih Ming-Chih Ho Source Type: research

Deep vein thrombosis after major orthopedic surgery in Taiwan: A prospective cross-sectional study and literature review
CONCLUSION: Nine out of 120 (7.5%) orthopedic patients without pharmacologic thromboprophylaxis developed postoperative sonographic DVT in our study. The DVT rate is consistent with other reports from various Asian countries and evidence from meta-analyses.PMID:35033412 | DOI:10.1016/j.jfma.2021.12.027 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 16, 2022 Category: General Medicine Authors: Hsuan-Yu Lin Ching-Yeh Lin Ying-Chih Huang Han-Ni Hsieh Ya-Wun Yang Ing-Lin Chang Ming-Ching Shen Source Type: research

Predictors of changes in preoperative tumor stage between dynamic computed tomography and gadoxetate disodium-enhanced magnetic resonance imaging for hepatocellular carcinoma
J Formos Med Assoc. 2022 Jan 12:S0929-6646(21)00593-3. doi: 10.1016/j.jfma.2021.12.026. Online ahead of print.ABSTRACTBACKGROUND/PURPOSE: Gadoxetate disodium-enhanced magnetic resonance imaging (EOB-MRI) has a higher diagnostic accuracy for hepatocellular carcinoma (HCC) than computed tomography (CT). However, indications for performing EOB-MRI after dynamic CT are not well defined. Therefore, we investigated the clinical factors associated with changes in the preoperative tumor stage between dynamic CT and EOB-MRI.METHODS: A prospective cohort was conducted from January 2014 to December 2017. 156 adult patients with clini...
Source: J Formos Med Assoc - January 16, 2022 Category: General Medicine Authors: Chih-Horng Wu Yu-Hsin Lee Po-Chin Liang Rey-Heng Hu Tiffany Ting-Fang Shih Ming-Chih Ho Source Type: research

Deep vein thrombosis after major orthopedic surgery in Taiwan: A prospective cross-sectional study and literature review
CONCLUSION: Nine out of 120 (7.5%) orthopedic patients without pharmacologic thromboprophylaxis developed postoperative sonographic DVT in our study. The DVT rate is consistent with other reports from various Asian countries and evidence from meta-analyses.PMID:35033412 | DOI:10.1016/j.jfma.2021.12.027 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 16, 2022 Category: General Medicine Authors: Hsuan-Yu Lin Ching-Yeh Lin Ying-Chih Huang Han-Ni Hsieh Ya-Wun Yang Ing-Lin Chang Ming-Ching Shen Source Type: research

Hotel-based quarantine center as a rapid response to COVID-19 outbreak, New Taipei, Taiwan, May to July 2021
J Formos Med Assoc. 2022 Jan 10:S0929-6646(22)00001-8. doi: 10.1016/j.jfma.2022.01.001. Online ahead of print.NO ABSTRACTPMID:35031199 | PMC:PMC8743618 | DOI:10.1016/j.jfma.2022.01.001 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 15, 2022 Category: General Medicine Authors: Huang-Wen Tsai Fang-Ming Hung Chun-Hsain Liao Heng-Fu Lin Source Type: research

Immunotherapy in anaplastic thyroid cancer: Case series
In conclusion, the treatment responses of immunotherapy, either alone or in combination with other therapies, were highly variable in patients with ATC and should be carefully monitored along with the side effects.PMID:35031200 | DOI:10.1016/j.jfma.2022.01.003 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 15, 2022 Category: General Medicine Authors: Shyang-Rong Shih Kuan-Hua Chen Kuan-Yu Lin Pan-Chyr Yang Kuen-Yuan Chen Chun-Wei Wang Chun-Nan Chen Chih-Feng Lin Chia-Chi Lin Source Type: research

Morbilliform rashes as an unusual manifestation of vaccine-induced immune thrombotic thrombocytopenia
J Formos Med Assoc. 2022 Jan 11:S0929-6646(21)00596-9. doi: 10.1016/j.jfma.2021.12.029. Online ahead of print.NO ABSTRACTPMID:35031201 | DOI:10.1016/j.jfma.2021.12.029 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 15, 2022 Category: General Medicine Authors: Wan-Ting Yang Po-Yu Liu Kuo-Lung Lai Source Type: research

Hotel-based quarantine center as a rapid response to COVID-19 outbreak, New Taipei, Taiwan, May to July 2021
J Formos Med Assoc. 2022 Jan 10:S0929-6646(22)00001-8. doi: 10.1016/j.jfma.2022.01.001. Online ahead of print.NO ABSTRACTPMID:35031199 | PMC:PMC8743618 | DOI:10.1016/j.jfma.2022.01.001 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 15, 2022 Category: General Medicine Authors: Huang-Wen Tsai Fang-Ming Hung Chun-Hsain Liao Heng-Fu Lin Source Type: research

Immunotherapy in anaplastic thyroid cancer: Case series
In conclusion, the treatment responses of immunotherapy, either alone or in combination with other therapies, were highly variable in patients with ATC and should be carefully monitored along with the side effects.PMID:35031200 | DOI:10.1016/j.jfma.2022.01.003 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 15, 2022 Category: General Medicine Authors: Shyang-Rong Shih Kuan-Hua Chen Kuan-Yu Lin Pan-Chyr Yang Kuen-Yuan Chen Chun-Wei Wang Chun-Nan Chen Chih-Feng Lin Chia-Chi Lin Source Type: research

Morbilliform rashes as an unusual manifestation of vaccine-induced immune thrombotic thrombocytopenia
J Formos Med Assoc. 2022 Jan 11:S0929-6646(21)00596-9. doi: 10.1016/j.jfma.2021.12.029. Online ahead of print.NO ABSTRACTPMID:35031201 | DOI:10.1016/j.jfma.2021.12.029 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 15, 2022 Category: General Medicine Authors: Wan-Ting Yang Po-Yu Liu Kuo-Lung Lai Source Type: research

Clinical manifestations and risk factors for poor visual outcomes of ocular sarcoidosis in Taiwan
J Formos Med Assoc. 2022 Jan 11:S0929-6646(21)00599-4. doi: 10.1016/j.jfma.2021.12.032. Online ahead of print.ABSTRACTPURPOSE: To assess ocular involvement in sarcoidosis and to analyze the manifestations of ocular sarcoidosis (OS) in Taiwan.METHODS: A retrospective review was performed in 364 patients diagnosed as sarcoidosis at National Taiwan University Hospital from 2015 to 2019. The OS diagnosis was based on the revised criteria of International Workshop on Ocular Sarcoidosis. Demographics, clinical manifestations, treatment and effects, complications, visual outcomes and risk factors of poor vision (
Source: J Formos Med Assoc - January 14, 2022 Category: General Medicine Authors: I-Wen Lai Chang-Ping Lin Yi-Ting Hsieh Po-Ting Yeh Source Type: research

Clinical manifestations and risk factors for poor visual outcomes of ocular sarcoidosis in Taiwan
J Formos Med Assoc. 2022 Jan 11:S0929-6646(21)00599-4. doi: 10.1016/j.jfma.2021.12.032. Online ahead of print.ABSTRACTPURPOSE: To assess ocular involvement in sarcoidosis and to analyze the manifestations of ocular sarcoidosis (OS) in Taiwan.METHODS: A retrospective review was performed in 364 patients diagnosed as sarcoidosis at National Taiwan University Hospital from 2015 to 2019. The OS diagnosis was based on the revised criteria of International Workshop on Ocular Sarcoidosis. Demographics, clinical manifestations, treatment and effects, complications, visual outcomes and risk factors of poor vision (
Source: J Formos Med Assoc - January 14, 2022 Category: General Medicine Authors: I-Wen Lai Chang-Ping Lin Yi-Ting Hsieh Po-Ting Yeh Source Type: research

Investigating early progression of Hodgkin lymphoma in a two-center analysis
J Formos Med Assoc. 2022 Jan 9:S0929-6646(21)00592-1. doi: 10.1016/j.jfma.2021.12.025. Online ahead of print.ABSTRACTBACKGROUND/PURPOSE: The early progression of disease (POD) of Hodgkin lymphoma (HL) leads to a poor prognosis. To identify risk factors for early POD, this retrospective two-center cohort analysis was conducted.METHODS: Medical records of HL patients between 1998 and 2020 from two referral centers were reviewed.RESULTS: Two-hundred and sixty-nine patients were analyzed. The distribution of early vs. advanced stages was 51.1 vs. 48.9%, respectively. The 5-year progression free survival (PFS) was 63%, and the ...
Source: J Formos Med Assoc - January 13, 2022 Category: General Medicine Authors: Ta-Chuan Yu Shan-Chi Yu Ren-Ching Wang Shih-Fan Lai Chieh-Lin Jerry Teng Jing-Wei Lin Wan-Ling Lin Tai-Chung Huang Source Type: research

Investigating early progression of Hodgkin lymphoma in a two-center analysis
J Formos Med Assoc. 2022 Jan 9:S0929-6646(21)00592-1. doi: 10.1016/j.jfma.2021.12.025. Online ahead of print.ABSTRACTBACKGROUND/PURPOSE: The early progression of disease (POD) of Hodgkin lymphoma (HL) leads to a poor prognosis. To identify risk factors for early POD, this retrospective two-center cohort analysis was conducted.METHODS: Medical records of HL patients between 1998 and 2020 from two referral centers were reviewed.RESULTS: Two-hundred and sixty-nine patients were analyzed. The distribution of early vs. advanced stages was 51.1 vs. 48.9%, respectively. The 5-year progression free survival (PFS) was 63%, and the ...
Source: J Formos Med Assoc - January 13, 2022 Category: General Medicine Authors: Ta-Chuan Yu Shan-Chi Yu Ren-Ching Wang Shih-Fan Lai Chieh-Lin Jerry Teng Jing-Wei Lin Wan-Ling Lin Tai-Chung Huang Source Type: research

Achievements and challenges in chronic kidney disease care in Taiwan
J Formos Med Assoc. 2022 Jan 8:S0929-6646(21)00581-7. doi: 10.1016/j.jfma.2021.12.016. Online ahead of print.NO ABSTRACTPMID:35016834 | DOI:10.1016/j.jfma.2021.12.016 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 12, 2022 Category: General Medicine Authors: Chih-Cheng Hsu Yung-Ho Hsu Mai-Szu Wu Shang-Jyh Hwang Source Type: research

Short stature leads to a diagnosis of Jansen-de Vries syndrome in two unrelated Taiwanese girls: A case report and literature review
J Formos Med Assoc. 2022 Jan 8:S0929-6646(21)00587-8. doi: 10.1016/j.jfma.2021.12.022. Online ahead of print.ABSTRACTShort stature and intellectual disability are two of the major components of many dysmorphic syndromes. Jansen-de Vries syndrome (JDVS) is a rare syndromic disorder that was discovered recently using next-generation sequencing. It is characterized by hypotonia, developmental delay, a dysmorphic face, short stature, and high pain threshold and is caused by the variants of the protein phosphatase magnesium-dependent 1D (PPM1D) gene. Here, we report the first two cases of PPM1D mutations in Taiwan; both had de ...
Source: J Formos Med Assoc - January 12, 2022 Category: General Medicine Authors: Meng-Ju Melody Tsai Ni-Chung Lee Yin-Hsiu Chien Wuh-Liang Hwu Yi-Ching Tung Source Type: research

Achievements and challenges in chronic kidney disease care in Taiwan
J Formos Med Assoc. 2022 Jan 8:S0929-6646(21)00581-7. doi: 10.1016/j.jfma.2021.12.016. Online ahead of print.NO ABSTRACTPMID:35016834 | DOI:10.1016/j.jfma.2021.12.016 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 12, 2022 Category: General Medicine Authors: Chih-Cheng Hsu Yung-Ho Hsu Mai-Szu Wu Shang-Jyh Hwang Source Type: research

Short stature leads to a diagnosis of Jansen-de Vries syndrome in two unrelated Taiwanese girls: A case report and literature review
J Formos Med Assoc. 2022 Jan 8:S0929-6646(21)00587-8. doi: 10.1016/j.jfma.2021.12.022. Online ahead of print.ABSTRACTShort stature and intellectual disability are two of the major components of many dysmorphic syndromes. Jansen-de Vries syndrome (JDVS) is a rare syndromic disorder that was discovered recently using next-generation sequencing. It is characterized by hypotonia, developmental delay, a dysmorphic face, short stature, and high pain threshold and is caused by the variants of the protein phosphatase magnesium-dependent 1D (PPM1D) gene. Here, we report the first two cases of PPM1D mutations in Taiwan; both had de ...
Source: J Formos Med Assoc - January 12, 2022 Category: General Medicine Authors: Meng-Ju Melody Tsai Ni-Chung Lee Yin-Hsiu Chien Wuh-Liang Hwu Yi-Ching Tung Source Type: research

Pityriasis Rosea-like eruptions following COVID-19 mRNA-1273 vaccination: A case report and literature review
J Formos Med Assoc. 2022 Jan 5:S0929-6646(21)00595-7. doi: 10.1016/j.jfma.2021.12.028. Online ahead of print.ABSTRACTPityriasis rosea (PR) is a self-limited disease with exanthematous papulosquamous rashes mostly associated with reactivation of human herpesvirus (HHV)-6 or HHV-7. PR-like eruptions, which occur along with peripheral eosinophilia, interface dermatitis, and eosinophils on histopathology, may result from medications or vaccinations. Previously, PR-like eruptions had been noted following vaccination for influenza or other vaccines. During this pandemic, acute COVID-19 infection has been related to PR or PR-like...
Source: J Formos Med Assoc - January 11, 2022 Category: General Medicine Authors: Chii-Shyan Wang Hsuan-Hsiang Chen Shih-Hao Liu Source Type: research

Influence of hemoglobin on blood pressure among people with GP.Mur blood type < sup > ☆ < /sup >
CONCLUSION: GP.Mur contributed to BP in both Hb-dependent and Hb-independent fashion. A pronounced impact of hemoglobin on BP likely requires sufficient Hb, as GP.Mur increased the sensitivity of SBP to Hb only in non-anemic Taiwanese men, and not in Taiwanese women or anemic men. The mechanism through which GP.Mur affected BP independent of Hb is unknown.PMID:35000824 | DOI:10.1016/j.jfma.2021.12.014 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 10, 2022 Category: General Medicine Authors: Yung-Chih Chen Kuang-Nan Hsu Jerry Cheng-Yen Lai Li-Yang Chen Mei-Shin Kuo Chiu-Chu Liao Kate Hsu Source Type: research

Influence of hemoglobin on blood pressure among people with GP.Mur blood type < sup > ☆ < /sup >
CONCLUSION: GP.Mur contributed to BP in both Hb-dependent and Hb-independent fashion. A pronounced impact of hemoglobin on BP likely requires sufficient Hb, as GP.Mur increased the sensitivity of SBP to Hb only in non-anemic Taiwanese men, and not in Taiwanese women or anemic men. The mechanism through which GP.Mur affected BP independent of Hb is unknown.PMID:35000824 | DOI:10.1016/j.jfma.2021.12.014 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 10, 2022 Category: General Medicine Authors: Yung-Chih Chen Kuang-Nan Hsu Jerry Cheng-Yen Lai Li-Yang Chen Mei-Shin Kuo Chiu-Chu Liao Kate Hsu Source Type: research

Nephrotoxins and acute kidney injury - The consensus of the Taiwan acute kidney injury Task Force
J Formos Med Assoc. 2022 Jan 5:S0929-6646(21)00572-6. doi: 10.1016/j.jfma.2021.12.007. Online ahead of print.ABSTRACTThe Taiwan Acute Kidney Injury (AKI) Task Force conducted a review of data and developed a consensus regarding nephrotoxins and AKI. This consensus covers: (1) contrast-associated AKI; (2) drug-induced nephrotoxicity; (3) prevention of drug-associated AKI; (4) follow up after AKI; (5) re-initiation of medication after AKI. Strategies for the avoidance of contrast media related AKI, including peri-procedural hydration, sodium bicarbonate solutions, oral N-acetylcysteine, and iso-osmolar/low-osmolar non-ionic ...
Source: J Formos Med Assoc - January 9, 2022 Category: General Medicine Authors: Wei-Chun Huang Mei-Tzu Wang Tai-Shuan Lai Kuo-Hua Lee Shih-Chieh Shao Chien-Hao Chen Chien-Hao Su Yih-Ting Chen Junne-Ming Sung Yung-Chang Chen Source Type: research

Hospitalization in patients with dialysis in Taiwan: A nationwide population-based observational study
CONCLUSION: Hospitalization rates continued to increase from 2010 to 2018. The high hospitalization rates for infection-related diseases and hemodialysis patients call for further strategies to be developed that reduce the hospitalization burden.PMID:34998659 | DOI:10.1016/j.jfma.2021.12.020 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 9, 2022 Category: General Medicine Authors: Chin-Chan Lee Chih-Cheng Hsu Ming-Huang Lin Kuan-Hsing Chen I-Wen Wu Source Type: research

Response to a Letter to Editor for article "Impacts of nocturia on quality of life, mental health, work limitation, and health care seeking in China, Taiwan and South Korea (LUTS Asia): Results from a cross-sectional, population-based study"
J Formos Med Assoc. 2022 Jan 5:S0929-6646(21)00583-0. doi: 10.1016/j.jfma.2021.12.018. Online ahead of print.NO ABSTRACTPMID:34998660 | DOI:10.1016/j.jfma.2021.12.018 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 9, 2022 Category: General Medicine Authors: Po-Ming Chow Yao-Chi Chuang Karina Chin Po Hsu Yuan-Chi Shen Ann Wei-Ju Hsieh Shih-Ping Liu Source Type: research

The management of postoperative upper alimentary tract fistulas: A single-center experience of endoscopic tissue glue repair and recommendations of a systematic review
CONCLUSIONS: The results suggest that no single approach toward UATF is superior in terms of success rate and healing time. The potential advantages of EGD tissue glue repair after drainage were more suitable for patients with postoperative UATF and multiple comorbidities.PMID:34998661 | DOI:10.1016/j.jfma.2021.12.021 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 9, 2022 Category: General Medicine Authors: Peng-Sheng Lai Chien-Te Pan Po-Chu Lee I-Rue Lai Chiung-Nien Chen Pei-Ming Huang Ming-Tsan Lin Source Type: research

Trends of treated hepatitis B, hepatitis C, and tuberculosis infection in long-term hemodialysis patients in Taiwan: A nationwide survey in 2010-2018
This study used reimbursement data from the Taiwan National Health Insurance Research Database. Long-term hemodialysis (HD) patients were defined as those receiving regular HD for more than 3 months. Treated HBV, HCV, and TB cases were defined according to the diagnosis codes, together with specified prescriptions. Liver malignancy and liver-related mortality were determined by the disease diagnosis.RESULTS: The long-term HD population in Taiwan grew from 57,539 in 2010 to 74,203 in 2018. The mean number of treated HBV, HCV, and TB cases in the HD population was 254 (3.9 per thousand HD patients), 136 (2.0 per thousand), a...
Source: J Formos Med Assoc - January 8, 2022 Category: General Medicine Authors: Jia-Jung Lee Jer-Ming Chang Lii-Jia Yang Chih-Cheng Hsu Ming-Huang Lin Ming-Yen Lin Source Type: research

Trends of treated hepatitis B, hepatitis C, and tuberculosis infection in long-term hemodialysis patients in Taiwan: A nationwide survey in 2010-2018
This study used reimbursement data from the Taiwan National Health Insurance Research Database. Long-term hemodialysis (HD) patients were defined as those receiving regular HD for more than 3 months. Treated HBV, HCV, and TB cases were defined according to the diagnosis codes, together with specified prescriptions. Liver malignancy and liver-related mortality were determined by the disease diagnosis.RESULTS: The long-term HD population in Taiwan grew from 57,539 in 2010 to 74,203 in 2018. The mean number of treated HBV, HCV, and TB cases in the HD population was 254 (3.9 per thousand HD patients), 136 (2.0 per thousand), a...
Source: J Formos Med Assoc - January 8, 2022 Category: General Medicine Authors: Jia-Jung Lee Jer-Ming Chang Lii-Jia Yang Chih-Cheng Hsu Ming-Huang Lin Ming-Yen Lin Source Type: research

Multidisciplinary care program in pre-end-stage kidney disease from 2010 to 2018 in Taiwan
CONCLUSION: The patients in the joining P4P program group were delivered more appropriate CKD care and were associated with better survival outcomes. Polices and action plans are needed to extend the coverage of and enrollment in the P4P program.PMID:34980548 | DOI:10.1016/j.jfma.2021.12.008 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 4, 2022 Category: General Medicine Authors: Ming-Yen Lin Min-Yu Chang Pei-Yu Wu Ping-Hsun Wu Ming-Huang Lin Chih-Cheng Hsu Jer-Ming Chang Shang-Jyh Hwang Yi-Wen Chiu Source Type: research

Healthcare utilization and expenditure among individuals with end-stage kidney disease in Taiwan
CONCLUSIONS: Medical expenditure, including both inpatient and outpatient costs, of the ESKD population continued to grow from 2010 to 2018. The non-dialysis cost in the ESKD population was mainly for cardiovascular disease management and vascular access care, for which prevention will always be challenging.PMID:34980549 | DOI:10.1016/j.jfma.2021.12.010 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 4, 2022 Category: General Medicine Authors: Chia-Chun Lee Chih-Cheng Hsu Ming-Huang Lin Junne-Ming Sung Te-Hui Kuo Source Type: research

Trends of medication used in patients with pre-ESKD from 2010 to 2018 in Taiwan
CONCLUSION: An overview of the trends of major medication usage and blood transfusion represented the continuously improving care quality in pre-ESKD patients in Taiwan. These trends were especially evident in patients enrolled in the pre-ESKD prevention program. This report also indirectly indicated the potential and long-term benefits of implementing CKD and pre-ESKD prevention programs.PMID:34980550 | DOI:10.1016/j.jfma.2021.12.012 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 4, 2022 Category: General Medicine Authors: Cheng-Jui Lin Ming-Hung Chien Meng-Ju Yang Ming-Huang Lin Chih-Cheng Hsu Pei-Lun Chu Source Type: research

Mortality rate of end-stage kidney disease patients in Taiwan
CONCLUSIONS: From 2010 to 2018, the reduced mortality in young patients and aging of the ESKD population might indicate that the quality of care in Taiwan for ESKD has improved. Furthermore, a better survival rate after dialysis initiation was observed in the pre-ESRD care program participants.PMID:34972608 | DOI:10.1016/j.jfma.2021.12.015 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 1, 2022 Category: General Medicine Authors: Bo-Sheng Wu Chia-Ling Helen Wei Chih-Yu Yang Ming-Huang Lin Chih-Cheng Hsu Yu-Juei Hsu Shih-Hua Lin Der-Cherng Tarng Source Type: research

Mortality rate of end-stage kidney disease patients in Taiwan
CONCLUSIONS: From 2010 to 2018, the reduced mortality in young patients and aging of the ESKD population might indicate that the quality of care in Taiwan for ESKD has improved. Furthermore, a better survival rate after dialysis initiation was observed in the pre-ESRD care program participants.PMID:34972608 | DOI:10.1016/j.jfma.2021.12.015 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 1, 2022 Category: General Medicine Authors: Bo-Sheng Wu Chia-Ling Helen Wei Chih-Yu Yang Ming-Huang Lin Chih-Cheng Hsu Yu-Juei Hsu Shih-Hua Lin Der-Cherng Tarng Source Type: research

Mortality rate of end-stage kidney disease patients in Taiwan
CONCLUSIONS: From 2010 to 2018, the reduced mortality in young patients and aging of the ESKD population might indicate that the quality of care in Taiwan for ESKD has improved. Furthermore, a better survival rate after dialysis initiation was observed in the pre-ESRD care program participants.PMID:34972608 | DOI:10.1016/j.jfma.2021.12.015 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 1, 2022 Category: General Medicine Authors: Bo-Sheng Wu Chia-Ling Helen Wei Chih-Yu Yang Ming-Huang Lin Chih-Cheng Hsu Yu-Juei Hsu Shih-Hua Lin Der-Cherng Tarng Source Type: research

Potential or contraindicated drug-drug interactions with antiretroviral therapy in real-world settings in Taiwan
CONCLUSION: Our study showed a low prevalence of contraindicated DDIs in the HIV population; however, more attention should be paid to a high proportion of potential DDIs. Strategies to avoid these DDIs should be implemented if possible. Further research that focuses on the long-term clinical impact of potential DDIs is warranted.PMID:34961668 | DOI:10.1016/j.jfma.2021.12.005 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 28, 2021 Category: General Medicine Authors: Chi-Chuan Wang Hsing-Jung Li Chi-Hao Shao Wang-Huei Sheng Source Type: research

Clinicopathological characteristics and prognosis in significantly thick acral lentiginous melanoma in Taiwan
J Formos Med Assoc. 2021 Dec 24:S0929-6646(21)00534-9. doi: 10.1016/j.jfma.2021.12.001. Online ahead of print.ABSTRACTThis retrospective cohort study enrolled 385 patients diagnosed with cutaneous melanoma from 1980 to 2021 in National Taiwan University Hospital (NTUH). The aim of this study was to investigate the relationship between thickness of primary melanoma lesions and disease outcome of melanoma patients, in particular, those diagnosed with acral lentiginous melanoma (ALM). The association between important clinicopathological characteristics other than tumor thickness and disease outcome was also analyzed. Surviva...
Source: J Formos Med Assoc - December 28, 2021 Category: General Medicine Authors: Tung-Lin Lee Ming-Hsien Lin Yi-Hua Liao Jau-Yu Liau Yi-Shuan Sheen Source Type: research

Potential or contraindicated drug-drug interactions with antiretroviral therapy in real-world settings in Taiwan
CONCLUSION: Our study showed a low prevalence of contraindicated DDIs in the HIV population; however, more attention should be paid to a high proportion of potential DDIs. Strategies to avoid these DDIs should be implemented if possible. Further research that focuses on the long-term clinical impact of potential DDIs is warranted.PMID:34961668 | DOI:10.1016/j.jfma.2021.12.005 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 28, 2021 Category: General Medicine Authors: Chi-Chuan Wang Hsing-Jung Li Chi-Hao Shao Wang-Huei Sheng Source Type: research

Clinicopathological characteristics and prognosis in significantly thick acral lentiginous melanoma in Taiwan
J Formos Med Assoc. 2021 Dec 24:S0929-6646(21)00534-9. doi: 10.1016/j.jfma.2021.12.001. Online ahead of print.ABSTRACTThis retrospective cohort study enrolled 385 patients diagnosed with cutaneous melanoma from 1980 to 2021 in National Taiwan University Hospital (NTUH). The aim of this study was to investigate the relationship between thickness of primary melanoma lesions and disease outcome of melanoma patients, in particular, those diagnosed with acral lentiginous melanoma (ALM). The association between important clinicopathological characteristics other than tumor thickness and disease outcome was also analyzed. Surviva...
Source: J Formos Med Assoc - December 28, 2021 Category: General Medicine Authors: Tung-Lin Lee Ming-Hsien Lin Yi-Hua Liao Jau-Yu Liau Yi-Shuan Sheen Source Type: research

Potential or contraindicated drug-drug interactions with antiretroviral therapy in real-world settings in Taiwan
CONCLUSION: Our study showed a low prevalence of contraindicated DDIs in the HIV population; however, more attention should be paid to a high proportion of potential DDIs. Strategies to avoid these DDIs should be implemented if possible. Further research that focuses on the long-term clinical impact of potential DDIs is warranted.PMID:34961668 | DOI:10.1016/j.jfma.2021.12.005 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 28, 2021 Category: General Medicine Authors: Chi-Chuan Wang Hsing-Jung Li Chi-Hao Shao Wang-Huei Sheng Source Type: research

Clinicopathological characteristics and prognosis in significantly thick acral lentiginous melanoma in Taiwan
J Formos Med Assoc. 2021 Dec 24:S0929-6646(21)00534-9. doi: 10.1016/j.jfma.2021.12.001. Online ahead of print.ABSTRACTThis retrospective cohort study enrolled 385 patients diagnosed with cutaneous melanoma from 1980 to 2021 in National Taiwan University Hospital (NTUH). The aim of this study was to investigate the relationship between thickness of primary melanoma lesions and disease outcome of melanoma patients, in particular, those diagnosed with acral lentiginous melanoma (ALM). The association between important clinicopathological characteristics other than tumor thickness and disease outcome was also analyzed. Surviva...
Source: J Formos Med Assoc - December 28, 2021 Category: General Medicine Authors: Tung-Lin Lee Ming-Hsien Lin Yi-Hua Liao Jau-Yu Liau Yi-Shuan Sheen Source Type: research

The application of ultrasound shear wave elastography in the prediction of paradoxical upgrading reaction in tuberculous lymphadenitis. a pilot study
J Formos Med Assoc. 2021 Dec 22:S0929-6646(21)00535-0. doi: 10.1016/j.jfma.2021.12.002. Online ahead of print.ABSTRACTBACKGROUND: Paradoxical upgrading reaction (PUR) indicates the unanticipated deterioration during therapy in patients with tuberculous lymphadenitis. We investigated the diagnostic performance of the ultrasonography and shear wave elastography (SWE) in predicting the therapeutic response of peripheral tuberculous lymphadenitis.METHODS: A prospective observational study was conducted from December 2017 to August 2020. Participants diagnosed with peripheral tuberculous lymphadenitis were included for a longit...
Source: J Formos Med Assoc - December 26, 2021 Category: General Medicine Authors: Yen-Lin Chen Yao-Wen Kuo Huey-Dong Wu Jann-Yuan Wang Hao-Chien Wang Source Type: research

Episodic weakness and axonal sensorimotor neuropathy caused by a mitochondrial MT-ATP6 mutation
We report a 20-year-old man with episodic weakness and axonal sensorimotor neuropathy since the age of 10 years. Analysis of the next generation sequencing data of the entire mitochondrial genome extracted from the blood revealed a homoplasmic m.9185T> C variant in MT-ATP6. Acetazolamide may be responsive for episodic weakness, and supplements with l-carnitine with coenzyme-Q10 seem to be beneficial as well. To the best of our knowledge, this is the first report in Taiwan which reveals episodic weakness and sensorimotor polyneuropathy as a unique phenotype of MT-ATP6 mutations.PMID:34953645 | DOI:10.1016/j.jfma.2021.12....
Source: J Formos Med Assoc - December 26, 2021 Category: General Medicine Authors: Tzu-Hsuan Su Ni-Chung Lee Chao-Szu Wu Steven Shinn-Forng Peng Pi-Chuan Fan Source Type: research

The application of ultrasound shear wave elastography in the prediction of paradoxical upgrading reaction in tuberculous lymphadenitis. a pilot study
J Formos Med Assoc. 2021 Dec 22:S0929-6646(21)00535-0. doi: 10.1016/j.jfma.2021.12.002. Online ahead of print.ABSTRACTBACKGROUND: Paradoxical upgrading reaction (PUR) indicates the unanticipated deterioration during therapy in patients with tuberculous lymphadenitis. We investigated the diagnostic performance of the ultrasonography and shear wave elastography (SWE) in predicting the therapeutic response of peripheral tuberculous lymphadenitis.METHODS: A prospective observational study was conducted from December 2017 to August 2020. Participants diagnosed with peripheral tuberculous lymphadenitis were included for a longit...
Source: J Formos Med Assoc - December 26, 2021 Category: General Medicine Authors: Yen-Lin Chen Yao-Wen Kuo Huey-Dong Wu Jann-Yuan Wang Hao-Chien Wang Source Type: research

Episodic weakness and axonal sensorimotor neuropathy caused by a mitochondrial MT-ATP6 mutation
We report a 20-year-old man with episodic weakness and axonal sensorimotor neuropathy since the age of 10 years. Analysis of the next generation sequencing data of the entire mitochondrial genome extracted from the blood revealed a homoplasmic m.9185T> C variant in MT-ATP6. Acetazolamide may be responsive for episodic weakness, and supplements with l-carnitine with coenzyme-Q10 seem to be beneficial as well. To the best of our knowledge, this is the first report in Taiwan which reveals episodic weakness and sensorimotor polyneuropathy as a unique phenotype of MT-ATP6 mutations.PMID:34953645 | DOI:10.1016/j.jfma.2021.12....
Source: J Formos Med Assoc - December 26, 2021 Category: General Medicine Authors: Tzu-Hsuan Su Ni-Chung Lee Chao-Szu Wu Steven Shinn-Forng Peng Pi-Chuan Fan Source Type: research

Neuropsychiatric symptoms and mortality among patients with mild cognitive impairment and dementia due to Alzheimer's disease
CONCLUSION: Mortality risk is high for patients with AD. Not only for AD, patients with MCI presenting with NPS, particularly mood symptoms, have high death risk.PMID:34933801 | DOI:10.1016/j.jfma.2021.12.004 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 22, 2021 Category: General Medicine Authors: Mei-Feng Huang Wei-Ju Lee Yi-Chun Yeh Yung-Shuan Lin Hsiu-Fen Lin Shuu-Jiun Wang Yi-Hsin Yang Cheng-Sheng Chen Jong-Ling Fuh Source Type: research

Neuropsychiatric symptoms and mortality among patients with mild cognitive impairment and dementia due to Alzheimer's disease
CONCLUSION: Mortality risk is high for patients with AD. Not only for AD, patients with MCI presenting with NPS, particularly mood symptoms, have high death risk.PMID:34933801 | DOI:10.1016/j.jfma.2021.12.004 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 22, 2021 Category: General Medicine Authors: Mei-Feng Huang Wei-Ju Lee Yi-Chun Yeh Yung-Shuan Lin Hsiu-Fen Lin Shuu-Jiun Wang Yi-Hsin Yang Cheng-Sheng Chen Jong-Ling Fuh Source Type: research

Neuropsychiatric symptoms and mortality among patients with mild cognitive impairment and dementia due to Alzheimer's disease
CONCLUSION: Mortality risk is high for patients with AD. Not only for AD, patients with MCI presenting with NPS, particularly mood symptoms, have high death risk.PMID:34933801 | DOI:10.1016/j.jfma.2021.12.004 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 22, 2021 Category: General Medicine Authors: Mei-Feng Huang Wei-Ju Lee Yi-Chun Yeh Yung-Shuan Lin Hsiu-Fen Lin Shuu-Jiun Wang Yi-Hsin Yang Cheng-Sheng Chen Jong-Ling Fuh Source Type: research