Suicide and associated psychosocial correlates among university students in Taiwan: A mixed-methods study.
CONCLUSION: While identifying several risk factors that cumulatively conduced to higher suicide risks, neuroticism served as a key element in the increased suicide risk among the university students. Suicide prevention strategies for university students should highlight stress management for those with neurotic trait and early suicide risk identification. Youth suicide prevention, Psychosocial correlates, Risk factors, Mixed-methods, Taiwan. PMID: 32046924 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - February 8, 2020 Category: General Medicine Authors: Anny Chen LY, Wu CY, Lee MB, Yang LT Tags: J Formos Med Assoc Source Type: research

Quality of life assessment during in  vitro fertilization treatment to improve pregnancy outcomes.
Quality of life assessment during in vitro fertilization treatment to improve pregnancy outcomes. J Formos Med Assoc. 2020 Feb 06;: Authors: Zhu P, Fung A, Woo BKP PMID: 32037262 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - February 6, 2020 Category: General Medicine Authors: Zhu P, Fung A, Woo BKP Tags: J Formos Med Assoc Source Type: research

Effects of a comprehensive physical therapy on moderate and severe obstructive sleep apnea- a preliminary randomized controlled trial.
CONCLUSION: This comprehensive physical therapy can be prescribed for the significant clinical improvement on sleep apnea for the patients with moderate and severe OSA. PMID: 32037263 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - February 6, 2020 Category: General Medicine Authors: Lin HY, Chang CJ, Chiang CC, Su PL, Lin CY, Hung CH Tags: J Formos Med Assoc Source Type: research

Characteristics of analytically confirmed illicit substance-using patients in the Emergency Department.
This study aimed to describe clinical presentations of patients who visited the ED because of acute illicit substance-related complications. METHODS: We performed a retrospective study between May 2017 and August 2018 on patients presenting to the ED with positive urine illicit substance analysis by LC-MS/MS. RESULTS: Of 203 patients with at least one illicit substance detected in their urine, 162 (79.8%) showed traditional illicit substances, and 56 (32.0%) showed new psychoactive substances (NPS). Methamphetamine was the most common illicit substance (67.9%). The most common NPS was ketamine (21.7%), followed b...
Source: J Formos Med Assoc - February 6, 2020 Category: General Medicine Authors: Weng TI, Chen LY, Chen JY, Chen PS, Hwa HL, Fang CC Tags: J Formos Med Assoc Source Type: research

Smart link of chronic atrophic gastritis with atrophic glossitis, gastric parietal cell antibody positivity, vitamin B12 deficiency, and hyperhomocysteinemia.
PMID: 32024596 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - February 3, 2020 Category: General Medicine Authors: Sun A, Yu-Fong Chang J, Chiang CP Tags: J Formos Med Assoc Source Type: research

Is chronic atrophic gastritis the missing link between atrophic glossitis, gastric parietal cell antibody positivity and hematological deficiencies?
PMID: 31992475 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 25, 2020 Category: General Medicine Authors: Pellicano R Tags: J Formos Med Assoc Source Type: research

Impact of periodontal disease and chewing ability on the quality of life of the elderly in an affluent community.
CONCLUSION: Among older adults in an affluent community, periodontal disease is an independent risk factor directly related to oral health-related QoL, whereas chewing ability is a mediator between QoL and removable denture-wearing. PMID: 31982268 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 23, 2020 Category: General Medicine Authors: Liang YH, Chou C, Chen YJ, Chou YF, Lin CY, Chou C, Wang TF Tags: J Formos Med Assoc Source Type: research

A case with cytomegalovirus colitis and toxic megacolon initially diagnosed as Crohn's disease.
PMID: 31973935 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 20, 2020 Category: General Medicine Authors: Chang SH, Sun HY, Shun CT, Wei SC Tags: J Formos Med Assoc Source Type: research

A novel GnRH-antagonist protocol by switching to medroxyprogesterone when patients being at risk of ovarian hyperstimulation syndrome during ovarian stimulation.
CONCLUSION: This study showed that MPA could sequentially replace GnRHant and effectively prevent premature LH surge after several days of GnRHant administration in patients being at high risk of OHSS during controlled ovarian stimulation. Switch protocol could individualize freeze-all policy and reduce the injection burden of GnRHant. PMID: 31969249 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 19, 2020 Category: General Medicine Authors: Huang TC, Lin YH, Pan SP, Tu YA, Huang CC, Chen MJ, Hwang JL, Chen SU Tags: J Formos Med Assoc Source Type: research

Rapid on-site cytologic evaluation by pulmonologist improved diagnostic accuracy of endobronchial ultrasound-guided transbronchial biopsy.
Abstract BACKGROUND/PURPOSE: Rapid on-site cytologic evaluation (ROSE) has been shown to improve the diagnostic accuracy of endobronchial ultrasound-guided transbronchial biopsy (EBUS-TBB). However, ROSE by a cytopathologist or cytotechnologist is not always available during the procedure. The purposes of this study were to verify that a pulmonologist, after receiving training in cytology, could accurately assess an EBUS-TBB specimen on-site, and to evaluate the contribution of ROSE to EBUS-TBB. METHODS: A retrospective chart review of patients who underwent EBUS-TBB for diagnosis of peripheral pulmonary lesi...
Source: J Formos Med Assoc - January 18, 2020 Category: General Medicine Authors: Lin CK, Jan IS, Yu KL, Chang LY, Fan HJ, Wen YF, Ho CC Tags: J Formos Med Assoc Source Type: research

Inhibition of HIF1A-AS1 impedes the arecoline-induced migration activity of human oral mucosal fibroblasts.
Abstract Long non-coding RNA hypoxia-inducible factor 1α-antisense RNA 1 (HIF1A-AS1) has been known to participate in various types of malignancies, but its role in the development of precancerous oral submucous fibrosis (OSF) has not been investigated. In the current study, we first observed the aberrant upregulation of HIF1A-AS1 in OSF tissues and fibrotic buccal mucosal fibroblasts (fBMFs) isolated from OSF specimens. Next, we demonstrated that administration of arecoline, a natural alkaloid that is found in areca nut, induced the elevation of HIF1A-AS1 in BMFs. This finding showed that the habit of areca...
Source: J Formos Med Assoc - January 17, 2020 Category: General Medicine Authors: Wang YK, Liu CM, Lin T, Fang CY, Yu CC, Yu CH Tags: J Formos Med Assoc Source Type: research

The presence and impact of herpes virus DNA in recipient cornea and aqueous humor on graft survival following penetrating keratoplasty.
CONCLUSION: There were high positive rates of HSV-1, HSV-2, and CMV DNA in recipient corneas and aqueous humor at the time of PKP, even among patients not suspected of latent viral infection. The presence of aqueous HSV-1 DNA was associated with higher risk of graft failure. PMID: 31948731 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 13, 2020 Category: General Medicine Authors: Jeng YT, Tsai CY, Kuo LL, Woung LC, Lin SY, Tsai IL Tags: J Formos Med Assoc Source Type: research

Improved appropriateness of anti-tuberculosis prescription by the expert prescription review program in Taiwan.
Abstract BACKGROUND: A nationwide program initiated by Taiwan CDC was conducted by the Taiwan Society of Tuberculosis and Lung Disease to improve the appropriateness of anti-TB prescriptions in Taiwan. METHODS: All anti-TB prescriptions from 12 hospitals across Taiwan were reviewed by experienced pulmonologists, according to the 2011 Taiwan TB treatment guidelines, between May and October 2013. The investigation period was divided into three stages: May to June, July to August, and September to October. The concordance rates between anti-TB prescriptions and the guidelines were compared among the three stages...
Source: J Formos Med Assoc - January 10, 2020 Category: General Medicine Authors: Hsieh MJ, Huang YW, Tsai YH, Feng JY, Su WJ, Taiwan Society of Tuberculosis and Lung Disease Tags: J Formos Med Assoc Source Type: research

The association of vitamin D with hepatitis B virus replication: Bystander rather than offender.
Abstract BACKGROUND/PURPOSE: Low vitamin D is frequent in hepatitis B virus (HBV)-infected patients and several studies show an inverse association of serum vitamin D level with HBV viral load. However, the causal relationship remains unclear. METHODS: HBV carriers receiving regular 6-month surveillance without current antiviral treatment or cirrhosis were invited to participate into this trial. The markers of HBV replication included serum HBV DNA and quantitative HBsAg (qHBsAg) levels. Those with undetectable HBV DNA or sufficient vitamin D levels, cancer or electrolyte imbalance were excluded. The eligible...
Source: J Formos Med Assoc - January 10, 2020 Category: General Medicine Authors: Wang CC, Tzeng IS, Su WC, Li CH, Lin HH, Yang CC, Kao JH Tags: J Formos Med Assoc Source Type: research

Effect of bFGF on the growth and matrix turnover of stem cells from human apical papilla: Role of MEK/ERK signaling.
CONCLUSION: SCAP cells express FGFRs. bFGF may stimulate proliferation and affect the matrix turnover of SCAP cells, possibly via stimulation of FGFRs and MEK/ERK signaling pathway. These results are useful for clinical therapies for apexogenesis and regeneration of pulpo-dentin complex. PMID: 31932202 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 10, 2020 Category: General Medicine Authors: Chang MC, Chen CY, Chang YC, Zhong BH, Wang YL, Yeung SY, Chang HH, Jeng JH Tags: J Formos Med Assoc Source Type: research

Accuracy of rapid Helicobacter pylori antigen tests for the surveillance of the updated prevalence of H. pylori in Taiwan.
CONCLUSION: The age-standardized prevalence of H. pylori infection in Taiwan was 21.8% in asymptomatic adults in 2018. The Vstrip® HpSA had equivalent performance as the ImmunoCard STAT!® HpSA, and can be used in future mass screening of H. pylori infection for gastric cancer prevention. PMID: 31926791 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 8, 2020 Category: General Medicine Authors: Fang YJ, Chen MJ, Chen CC, Lee JY, Yang TH, Yu CC, Chiu MC, Kuo CC, Weng YJ, Bair MJ, Wu MS, Luo JC, Liou JM Tags: J Formos Med Assoc Source Type: research

Multiple-locus variable-number tandem-repeat analysis (MLVA) of macrolide-susceptible and -resistant Mycoplasma pneumoniae in children in Taiwan.
Abstract BACKGROUND/PURPOSE: To date, molecular typing studies on Mycoplasma pneumoniae are limited. We evaluated the molecular types of Mycoplasma pneumoniae in pediatric patients in Taiwan in 2016. METHODS: We used real-time quantitative PCR on respiratory specimens to identify M. pneumoniae in children with community-acquired pneumonia. The domain V of their 23S rRNA were sequenced for detection of macrolide-resistant point mutations. Molecular typing with multiple locus variable-number tandem repeat analysis (MLVA) was done for both macrolide-susceptible and -resistance M. pneumoniae samples. RESULTS...
Source: J Formos Med Assoc - January 7, 2020 Category: General Medicine Authors: Lu CY, Yen TY, Chang LY, Liau YJ, Liu HH, Huang LM Tags: J Formos Med Assoc Source Type: research

Author reply to Letter to Editor "mental health and support of LGBTQ community in Asian culture".
Author reply to Letter to Editor "mental health and support of LGBTQ community in Asian culture". J Formos Med Assoc. 2020 Jan 07;: Authors: Yen CF PMID: 31924378 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 7, 2020 Category: General Medicine Authors: Yen CF Tags: J Formos Med Assoc Source Type: research

Clinical factors associated with treatment toxicity of pemetrexed plus platinum in elderly patients with non-small cell lung cancer.
CONCLUSION: High SCS and carboplatin use were associated with hematological toxicities with pemetrexed plus platinum use in elderly patients with NSCLC. PMID: 31917064 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 6, 2020 Category: General Medicine Authors: Chen CY, Chen KY, Shih JY, Yu CJ Tags: J Formos Med Assoc Source Type: research

Endoscopic management of strictures in patients with Crohn's disease - A multi-center experience in Taiwan.
CONCLUSION: EBD is a safe and effective procedure for CD-related stricture, with a 83.3% success rate in Taiwan. PMID: 31917065 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 6, 2020 Category: General Medicine Authors: Chang CW, Tu CH, Chou JW, Huang TY, Hsu WH, Wang YP, Chen CC, Chung CS, Lin CP, Lin WC, Tai CM, Wang HY, Chen MJ Tags: J Formos Med Assoc Source Type: research

The impacts of intra-arterial chemotherapy on head and neck microvascular reconstruction.
CONCLUSION: Despite treating local advanced head and neck cancers with good results, IA chemotherapy may cause subsequent deleterious effects on local tissue due to the high concentration of cytotoxic chemotherapeutic agents. Surgeons should be cautious in selection of recipient vessels when performing microvascular reconstruction. PMID: 31902466 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - January 2, 2020 Category: General Medicine Authors: Kuan CH, Chung MJ, Hong RL, Tseng TY, Tai HC, Cheng NC, Hsieh JH, Horng SY, Lai HS Tags: J Formos Med Assoc Source Type: research

Biomechanical effect of implant design on four implants supporting mandibular full-arch fixed dentures: In  vitro test and finite element analysis.
This study evaluated the all-on-four treatment with four osseointegrated implants in terms of the biomechanical effects of implant design and loading position on the implant and surrounding bone by using both in vitro strain gauge tests and three-dimensional (3D) finite element (FE) analyses. METHODS: Both in vitro and 3D FE models were constructed with placing NobelSpeedy and NobelActive implants as well as a titanium framework in an edentulous jawbone based on the concept of all-on-four treatment. Three types of loads were applied: at the central incisor area (loading position 1) and at the molar regions w...
Source: J Formos Med Assoc - December 26, 2019 Category: General Medicine Authors: Wu AY, Hsu JT, Fuh LJ, Huang HL Tags: J Formos Med Assoc Source Type: research

Functions and therapeutic targets of Siglec-mediated infections, inflammations and cancers.
Abstract Siglecs, sialic acid (SA)-binding immunoglobulin (Ig)-like lectins, belong to a family of Ig-like lectins. All Siglecs have at least two domains including an extracellular domain with variable (V) and constant (C)-set immunoglobulin (Ig) regions, and a transmembrane domain. Some of the Siglecs (Siglec-2-12, -17, -E, -F and -G) with three domains including immunoreceptor tyrosine-based inhibitory motif associated with Src homology 2 (SH2) tyrosine phosphatases (SHP1/2) usually deliver an inhibitory signal. Certain Siglecs (Siglec-14, -15, -16 and -H) containing no intracellular domain carry certain basic a...
Source: J Formos Med Assoc - December 24, 2019 Category: General Medicine Authors: Lin CH, Yeh YC, Yang KD Tags: J Formos Med Assoc Source Type: research

Clinical consideration in evaluating soreness symptoms of fibromyalgia.
PMID: 31862232 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 17, 2019 Category: General Medicine Authors: Kawashita T, Dunnsiri T, Shu S, Woo BKP Tags: J Formos Med Assoc Source Type: research

Taiwan nutritional consensus on the nutrition management for gastric cancer patients receiving gastrectomy.
Abstract Currently, consensus reports on the nutritional management for gastric cancer patients receiving gastric resection are lacking. The Gastroenterological Society of Taiwan therefore organized the Taiwan Gastric Cancer Nutritional Consensus Team to provide an overview of evidence and recommendations on nutritional support for gastric cancer patients undergoing gastrectomy. This consensus statement on the nutritional support for gastric cancer patients has two major sections:(1)perioperative nutritional support; and (2)long-term postoperative nutritional care. Thirty Taiwan medical experts conducted a consens...
Source: J Formos Med Assoc - December 16, 2019 Category: General Medicine Authors: Hsu PI, Chuah SK, Lin JT, Huang SW, Lo JC, Rau KM, Chen IS, Hsu HY, Sheu BS, Chang WK, Wu DC Tags: J Formos Med Assoc Source Type: research

A neonate with imperforate anus and accessory scrotum with scrotal bifida.
PMID: 31843291 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 13, 2019 Category: General Medicine Authors: Wang YF, Chou HC, Chen CY, Tsao PN Tags: J Formos Med Assoc Source Type: research

Authors' response to the Letter to the Editor on "Clinical consideration in evaluating soreness symptoms of fibromyalgia".
Authors' response to the Letter to the Editor on "Clinical consideration in evaluating soreness symptoms of fibromyalgia". J Formos Med Assoc. 2019 Dec 13;: Authors: Chang KV, Hung CH, Sun WZ, Wu WT, Lai CL, Han DS, Chen CC PMID: 31843292 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 13, 2019 Category: General Medicine Authors: Authors' response to the Letter to the Editor on "Clinical consideration in evaluating soreness symptoms of fibromyalgia". Tags: J Formos Med Assoc Source Type: research

Risks of post-traumatic stress disorder among emergency medical technicians who responded to the 2016 Taiwan earthquake.
Abstract BACKGROUND: Few studies have explored the field experiences and risk factors related to post-traumatic stress disorder (PTSD) among disaster rescue workers. METHODS: A 6.4-magnitude earthquake struck southern Taiwan on February 6, 2016. A standardized, paper-based, self-administered survey questionnaire including demographic information, field experiences and the Post-Traumatic Stress Disorder Checklist (PCL) was conducted among emergency medical technicians (EMTs) one month after the earthquake. A multivariate regression model was used to analyze the associations between risk factors and the PCL. A ...
Source: J Formos Med Assoc - December 12, 2019 Category: General Medicine Authors: Ma IC, Chang WH, Wu CL, Lin CH Tags: J Formos Med Assoc Source Type: research

Coffee consumption and hepatocellular carcinoma in patients with HBeAg negative chronic hepatitis B.
PMID: 31839524 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 12, 2019 Category: General Medicine Authors: Chen CL, Chang WC, Hsu CS Tags: J Formos Med Assoc Source Type: research

Sulforaphane improves voiding function via the preserving mitochondrial function in diabetic rats.
CONCLUSION: We suggest that sulforaphanevia activating Nrf-2/HO-1 signaling preserved mitochondrial function and suppressed DM-induced ROS, endoplasmic reticulum stress, apoptosis and voiding dysfunction. PMID: 31837923 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 11, 2019 Category: General Medicine Authors: Lin CF, Chueh TH, Chung CH, Chung SD, Chang TC, Chien CT Tags: J Formos Med Assoc Source Type: research

Detection of Ehrlichia chaffeensis in a febrile patient in Kinmen, an offshore island of Taiwan.
PMID: 31831322 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 9, 2019 Category: General Medicine Authors: Yen TY, Tung YJ, Wang HC, Tsai KH Tags: J Formos Med Assoc Source Type: research

Association of Ang-2, vWF, and EVLWI with risk of mortality in sepsis patients with concomitant ARDS: A retrospective study.
CONCLUSION: The study findings indicate that Ang-2 levels and EVLWI at 24 h and 48 h after admission are significantly associated with the risk of mortality. PMID: 31822372 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 7, 2019 Category: General Medicine Authors: Ma S, Zhao ML, Wang K, Yue YF, Sun RQ, Zhang RM, Wang SF, Sun G, Xie HQ, Yu Y, Wang L, Zhang WP, Wang SJ, Zhu HC, Wang L Tags: J Formos Med Assoc Source Type: research

Management and clinical outcomes of patients with recurrent/progressive ovarian clear cell carcinoma.
Abstract BACKGROUND/PURPOSE: Ovarian clear cell carcinoma (OCCC) with recurrence/progression after treatment has dismal prognosis. We aimed to investigate the management and outcomes of such patients. METHODS: OCCC patients who were treated between 2000 and 2013 with cancer recurrence or progression after primary treatment were analyzed. Univariate and multivariate analyses were used to identify the independent predictors of survival after recurrence (SAR) and cancer-specific survival (CSS). RESULTS: A total of 64 patients experienced treatment failure (49 recurred after remission and 15 progressed witho...
Source: J Formos Med Assoc - December 6, 2019 Category: General Medicine Authors: Huang HJ, Yang LY, Tung HJ, Ku FC, Wu RC, Tang YH, Chang WY, Jung SM, Wang CC, Lin CT, Liu FY, Lin G, Chen MY, Chou HH, Chang TC, Chao A, Lai CH Tags: J Formos Med Assoc Source Type: research

Prognostic factors for renal transplant graft survival in a retrospective cohort of 1000 cases: The role of desensitization therapy.
CONCLUSION: HLA mismatches, delayed graft function with or without recovery, and AMR were significant factors for poor graft survival. Detection and desensitization of DSA currently might be inadequate to improve the long-term outcome of renal transplantation. PMID: 31818714 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 6, 2019 Category: General Medicine Authors: Lee CY, Yang CY, Lin WC, Chen CC, Tsai MK Tags: J Formos Med Assoc Source Type: research

l-Theanine improves functional recovery after traumatic spinal cord injury in rats.
CONCLUSION: Our findings revealed that LT can enhance the recovery of behavioral motor functions after SCI in rats, which related to the suppression of post-traumatic oxidative response, neural inflammation, and apoptosis. This evidence indicates that LT holds considerable potential for use in the clinical treatment/prevention of SCI-induced motor dysfunction. PMID: 31812333 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 5, 2019 Category: General Medicine Authors: Yang CC, Chang KC, Wang MH, Tseng HC, Soung HS, Fang CH, Lin YW, Li KY, Tsai CC Tags: J Formos Med Assoc Source Type: research

Comparison of the vault prolapse rate after vaginal hysterectomy with or without residual uterine ligament ligations: A retrospective cohort study.
Abstract PURPOSE: To evaluate the post-hysterectomy vault prolapse (PHVP) rates performed using different methods of vaginal total hysterectomy (VTH). METHODS: A total of 251 women who underwent VTH with/without concomitant surgeries between January 1986 and December 2001 in a tertiary center. Thirty-eight women were excluded due to not only a vaginal approach. Of the remaining 213 women, 129 and 84 underwent VTH via the Tsuzi method with residual uterine ligament ligations (ligations group) and traditional VTH (without ligations group), respectively. The χ2 and Mann-Whitney U tests were applied appropria...
Source: J Formos Med Assoc - December 5, 2019 Category: General Medicine Authors: Wu PC, Hsiao SM, Chen CH, Lin HH Tags: J Formos Med Assoc Source Type: research

An atypical hyperosmolar hyperglycemic state and diabetic ketoacidosis induced by sodium-glucose cotransporter-2 inhibitors: A case report.
Abstract Sodium-glucose cotransporter-2 (SGLT-2) inhibitors have become the best choice of second-line oral antidiabetic drugs for patients with heart or chronic kidney disease. However, it is not clear how safe this treatment is for elderly patients, especially Asians, who are known to be more insulin deficient than Caucasian individuals with a similar insulin resistance. Here, we report a case concerning an elderly patient with type 2 diabetes mellitus without insulin dependence, whose antidiabetic medication had recently been changed to include an SGLT-2 inhibitor. The patient presented with an atypical hyperos...
Source: J Formos Med Assoc - December 5, 2019 Category: General Medicine Authors: Wang CT, Chang CW, Lu YC, Lam HC, Ku SJ, Tseng KB, Kao YH Tags: J Formos Med Assoc Source Type: research

Nasogastric tube decompression is unnecessary in patients undergoing laparoscopic nephroureterectomy for localized upper tract urothelial carcinoma.
CONCLUSIONS: Surgery-naïve patients with localized UTUC received LNU without peri-operative NGT is safe and feasible. PMID: 31813657 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 5, 2019 Category: General Medicine Authors: Hsu FS, Huang WY, Chen YF, Wu LY, Wang SM, Huang KH Tags: J Formos Med Assoc Source Type: research

The efficacy of pentosan polysulfate monotherapy for preventing recurrent urinary tract infections in women: A multicenter open-label randomized controlled trial.
CONCLUSION: Among women with recurrent UTI, 16-week PPS monotherapy significantly reduced UTI recurrence when compared with the control group. PMID: 31813658 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 5, 2019 Category: General Medicine Authors: Tseng CS, Chang SJ, Meng E, Chang HC, Lee YJ Tags: J Formos Med Assoc Source Type: research

Bilevel Positive Airway Pressure ventilation efficiently improves respiratory distress in initial hours treating children with severe asthma exacerbation.
Abstract OBJECTIVE: Treatment of severe asthma exacerbation could be challenging, especially in the initial hours of acute attack when systemic corticosteroid is yet to take effect. In spite of using inhaled agents, the role of non-invasive ventilation (NIV), including Bilevel Positive Airway Pressure (BiPAP), had been addressed recently. METHODS: We reviewed 5-year experience in our hospital for records of patients who were admitted to pediatric intensive care unit because of severe asthma attack. The included admission records from 2012 to 2017 were grouped according to BiPAP use (Yes/No). Clinical paramete...
Source: J Formos Med Assoc - December 2, 2019 Category: General Medicine Authors: Kang CM, Wu ET, Wang CC, Lu F, Chiang BL, Yen TA Tags: J Formos Med Assoc Source Type: research

Overview of the important policies for children and youth welfare in Taiwan.
PMID: 31806385 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 2, 2019 Category: General Medicine Authors: Chien HJ, Chang WC Tags: J Formos Med Assoc Source Type: research

Evaluation of the efficacy and safety of TWHF in diabetic nephropathy patients with overt proteinuria and normal eGFR.
CONCLUSION: TWHF is more effective than valsartan monotherapy in reduction of proteinuria in DN patients with overt proteinuria and normal eGFR, but with more adverse effects. PMID: 31801679 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 1, 2019 Category: General Medicine Authors: Xiong C, Li L, Bo W, Chen H, XiaoWei L, Hongbao L, Peng Z Tags: J Formos Med Assoc Source Type: research

Coffee consumption and cirrhosis-related complications with special reference to hepatocellular carcinoma.
PMID: 31801680 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - December 1, 2019 Category: General Medicine Authors: Kawada T Tags: J Formos Med Assoc Source Type: research

Common mental disorders in Taiwanese consumers of commercial low-dose computed tomography lung cancer screening: Comparison with a nationally representative sample.
CONCLUSION: Commercial LDCT lung cancer screening users may have a positive association with probable CMDs compared to the general population. Screening programs should consider including criteria and providing psychoeducation to improve the physical and mental outcomes of participants. CLINICAL TRIAL REGISTRATION: Purely observational studies (those in which the assignment of the medical intervention is not at the discretion of the investigator) do not require registration. PMID: 31787488 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 28, 2019 Category: General Medicine Authors: Chen CC, Wu WC, Chang SS, Chang CB, Yang CJ, Su HK, Chan DD Tags: J Formos Med Assoc Source Type: research

The gestational effect of antenatal corticosteroids on respiratory distress syndrome in very low birth weight infants: A  population-based study.
The gestational effect of antenatal corticosteroids on respiratory distress syndrome in very low birth weight infants: A population-based study. J Formos Med Assoc. 2019 Nov 21;: Authors: Liu SY, Yang HI, Chen CY, Chou HC, Hsieh WS, Tsou KI, Tsao PN, Taiwan Premature Infant Follow-up Network Abstract BACKGROUND/PURPOSE: The aim of this study was to evaluate the efficacy of antenatal corticosteroids for preventing very low birth weight (VLBW) infants with respiratory distress syndrome (RDS) from surfactant use at different gestational ages (GA). METHODS: We retrospectively analyzed the VLBW p...
Source: J Formos Med Assoc - November 21, 2019 Category: General Medicine Authors: Liu SY, Yang HI, Chen CY, Chou HC, Hsieh WS, Tsou KI, Tsao PN, Taiwan Premature Infant Follow-up Network Tags: J Formos Med Assoc Source Type: research

Fluoroscopic-guided nasogastric tube placement in patients with advanced head and neck cancers.
CONCLUSION: Our results show that fluoroscopic-guided NGT placement is a highly safe and effective procedure for patients with advanced HNC requiring enteral feeding. PMID: 31759750 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 21, 2019 Category: General Medicine Authors: Chen PT, Lee BC, Huang YC, Chang YC, Tzeng HL, Liu KL Tags: J Formos Med Assoc Source Type: research

Impact of sarcopenia and its diagnostic criteria on hospitalization and mortality in chronic hemodialysis patients: A 3-year longitudinal study.
CONCLUSION: Muscle functionality and quality can predict hospitalization and overall survival in chronic hemodialysis patients, better than muscle mass. PMID: 31744647 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 16, 2019 Category: General Medicine Authors: Lin YL, Liou HH, Wang CH, Lai YH, Kuo CH, Chen SY, Hsu BG Tags: J Formos Med Assoc Source Type: research

Association between interleukin-8 rs4073 polymorphism and prostate cancer: A meta-analysis.
CONCLUSION: The major findings of this meta-analysis suggested that IL-8 rs4073 polymorphism is significantly associated with risk of prostate cancer. PMID: 31718853 [PubMed - as supplied by publisher] (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - November 9, 2019 Category: General Medicine Authors: Chen CH, Ho CH, Hu SW, Tzou KY, Wang YH, Wu CC Tags: J Formos Med Assoc Source Type: research

Evaluating soreness symptoms of fibromyalgia: Establishment and validation of the Revised Fibromyalgia Impact Questionnaire with Integration of Soreness Assessment.
Abstract BACKGROUND: Fibromyalgia is a chronic disorder characterized by widespread musculoskeletal pain. A common complaint is soreness. However, until now, no assessment tool is available to address soreness and evaluate its impact on disease severity. We aimed to establish a questionnaire for soreness assessment and to evaluate its validity in fibromyalgia patients. METHODS: Patients diagnosed with fibromyalgia per the American College of Rheumatology criteria (2011) were recruited. The Revised Fibromyalgia Impact Questionnaire with an integration of Soreness Assessment (FIQRS) was established by adding fi...
Source: J Formos Med Assoc - November 9, 2019 Category: General Medicine Authors: Chang KV, Hung CH, Sun WZ, Wu WT, Lai CL, Han DS, Chen CC Tags: J Formos Med Assoc Source Type: research

Antiplatelet agents and anticoagulants increased the bleeding risk of bedside percutaneous dilational tracheostomy in critically ill patients.
Abstract BACKGROUND: The main objective of this study was to investigate the safety of bedside percutaneous dilational tracheostomy (PDT) by pulmonologists in critically ill patients, and the factors associated with complications resulting from PDT. METHODS: We retrospectively enrolled critically ill patients who had undergone bedside PDT in the intensive care units (ICUs) and respiratory care center from February 2016 to December 2018. RESULTS: A total of 312 patients were included for analysis, with a mean age of 69.6 ± 17.7 years. Two hundred and eight of the patients were male (66.7%...
Source: J Formos Med Assoc - November 2, 2019 Category: General Medicine Authors: Huang YH, Tseng CH, Chan MC, Lee BJ, Lin CH, Chang GC Tags: J Formos Med Assoc Source Type: research