Thoracic manifestations of tularaemia: a case series
ConclusionsPulmonary tularaemia may occur after tick bites and without extrathoracic manifestations. In patients who present with thoracic lymphadenopathy and pulmonary consolidations and who are exposed to increased outdoor activities, tularaemia should be included in the diagnostic pathway. Histologically, the presence of neutrophil –granulocyte infiltrations might help to distinguish tularaemia from other granulomatous infections, e.g. tuberculosis. The combination of quinolone–rifampicin rather than i.v. gentamicin reduced length of hospital stay in two patients. (Source: Infection)
Source: Infection - March 8, 2024 Category: Infectious Diseases Source Type: research

Copper affects virulence and diverse phenotypes of uropathogenic Proteus mirabilis
CONCLUSION: The finding of copper-mediated virulence and fitness reinforced the importance of copper for prevention and therapeutic interventions against P. mirabilis infections. As such, this study could facilitate the copper-based strategies against UTI by P. mirabilis.PMID:38453541 | DOI:10.1016/j.jmii.2024.02.007 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - March 7, 2024 Category: Microbiology Authors: Wei-Syuan Huang Yuan-Ju Lee Lu Wang Hsuan-Hsuan Chen Yueh-Jung Chao Vivien Cheng Shwu-Jen Liaw Source Type: research

Copper affects virulence and diverse phenotypes of uropathogenic Proteus mirabilis
CONCLUSION: The finding of copper-mediated virulence and fitness reinforced the importance of copper for prevention and therapeutic interventions against P. mirabilis infections. As such, this study could facilitate the copper-based strategies against UTI by P. mirabilis.PMID:38453541 | DOI:10.1016/j.jmii.2024.02.007 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - March 7, 2024 Category: Microbiology Authors: Wei-Syuan Huang Yuan-Ju Lee Lu Wang Hsuan-Hsuan Chen Yueh-Jung Chao Vivien Cheng Shwu-Jen Liaw Source Type: research

Antimicrobial prophylaxis protocol based on rectal swab culture before prostate biopsy to prevent infectious complications: a prospective randomized comparative study
ConclusionsIncidence of FQ resistance in the intestinal flora of our local population was prevalent. Risk factor for resistance was the use of FQ within the last 6  months. TAP adapted to rectal swab, mainly with third-generation cephalosporins, significantly reduced the rate of infectious complications after (TRUS-BP). (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - March 7, 2024 Category: Urology & Nephrology Source Type: research

Antibiotic resistance of ESKAPE group-microorganisms in health institutions from Hermosillo and Ciudad Obreg ón, Sonora, México
IntroductionEnterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. are microorganisms referred as the ESKAPE group pathogens. These microorganisms have generated great concern in health institutions around the world since most of them have resistance to multiple antibiotics and cause most infections associated with healthcare, as well as community infections. The aim of this study was the analysis of antibiotic resistance in microorganisms of the ESKAPE group, recovered from clinical samples in 11 health institutions from Hermosillo and Ciu...
Source: Frontiers in cellular and infection microbiology - March 7, 2024 Category: Microbiology Source Type: research

Antimicrobial resistance and public and animal health risks associated with pathogenic Escherichia coli isolated from calves
Comp Immunol Microbiol Infect Dis. 2024 Feb 19;107:102149. doi: 10.1016/j.cimid.2024.102149. Online ahead of print.ABSTRACTWe aimed to determine the antimicrobial susceptibility profile of pathogenic Escherichia coli strains isolated from fecal samples of calves and buffalo calves (2008-2013), in Minas Gerais, Brazil, as well as the frequency of O157 gene and strains carrying extended-spectrum beta-lactamases (ESBL) and mobile colistin resistance (mcr) genes. E. coli strains (n=518) were tested for susceptibility against ten antimicrobials. Tetracycline was the antimicrobial with the highest resistance rate (382/518), foll...
Source: Comparative immunology, microbiology and infectious diseases. - March 5, 2024 Category: Allergy & Immunology Authors: Dirc éia Aparecida da Costa Custódio Carine Rodrigues Pereira Maysa Serpa Gon çalves Anna Cec ília Trolesi Reis Borges Costa Pedro Felipe Rodrigues de Oliveira Bruna Henrique Pinto da Silva Giovanna Botelho Carneiro Fernanda Morcatti Coura Andrey Pere Source Type: research

Ecological and human health risk assessment of Pharmaceutical compounds in the Sirsa River of Indian Himalayas
This study investigated the distribution, and ecological and human health risks of four most frequently used pharmaceuticals [ciprofloxacin (CIP), norfloxacin (NOR), cetirizine (CTZ) and citalopram oxalate (ECP)] when co-occurring with metal ions in the Sirsa river water of the BBN region. The concentration range of the selected pharmaceuticals was between 'not detected' to 50 μgL-1 with some exception for CIP (50-100 μg L-1) and CTZ (100-150 μg L-1) in locations directly receiving wastewater discharges. A significant correlation was found between the occurrences of NOR and Al (r2 = 0.65; p = 0.01), and CTZ and K (r2 = ...
Source: Environmental Pollution - March 5, 2024 Category: Environmental Health Authors: Arohi Dixit Himanshu Pandey Rajiv Rana Anil Kumar Rajkumar Herojeet Renu Lata Raj Mukhopadhyay Santanu Mukherjee Binoy Sarkar Source Type: research

Antimicrobial resistance and public and animal health risks associated with pathogenic Escherichia coli isolated from calves
Comp Immunol Microbiol Infect Dis. 2024 Feb 19;107:102149. doi: 10.1016/j.cimid.2024.102149. Online ahead of print.ABSTRACTWe aimed to determine the antimicrobial susceptibility profile of pathogenic Escherichia coli strains isolated from fecal samples of calves and buffalo calves (2008-2013), in Minas Gerais, Brazil, as well as the frequency of O157 gene and strains carrying extended-spectrum beta-lactamases (ESBL) and mobile colistin resistance (mcr) genes. E. coli strains (n=518) were tested for susceptibility against ten antimicrobials. Tetracycline was the antimicrobial with the highest resistance rate (382/518), foll...
Source: Comparative immunology, microbiology and infectious diseases. - March 5, 2024 Category: Allergy & Immunology Authors: Dirc éia Aparecida da Costa Custódio Carine Rodrigues Pereira Maysa Serpa Gon çalves Anna Cec ília Trolesi Reis Borges Costa Pedro Felipe Rodrigues de Oliveira Bruna Henrique Pinto da Silva Giovanna Botelho Carneiro Fernanda Morcatti Coura Andrey Pere Source Type: research

Pancytopenia following adjuvant therapy with interferon gamma (IFN- γ) in a patient with disseminated nocardiosis
We report a case of pancytopenia following treatment with recombinant interferon gamma (IFN- γ) in a patient with disseminated nocardiosis. A 78-year-old woman presented with non-specific symptoms of general weakness, cough, fever, right-hand paresis, unsteady gait, and vision deterioration. Her medical record revealed multiple allergic reactions, notably to salicylates (including aspirin) , histamines, penicillin, ciprofloxacin, erythromycin, bisoprolol, and iodide. She reported having Henoch–Schönlein purpura, asthma, and arterial hypertension. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - March 5, 2024 Category: Infectious Diseases Authors: Thomas Derungs, Denis Poddubnyy, Thomas Schneider Tags: Case Report Source Type: research

Pancytopenia following adjuvant therapy with interferon-gamma in a patient with disseminated nocardiosis
We report a case of pancytopenia following treatment with recombinant interferon-gamma (IFN- γ) in a patient with disseminated nocardiosis. A 78-year-old woman presented with non-specific symptoms of general weakness, cough, fever, right-hand paresis, unsteady gait, and vision deterioration. Her medical record revealed multiple allergic reactions, notably to salicylates (including aspirin) , histamines, penicillin, ciprofloxacin, erythromycin, bisoprolol, and iodide. She reported having Henoch–Schönlein purpura, asthma, and arterial hypertension. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - March 5, 2024 Category: Infectious Diseases Authors: Thomas Derungs, Denis Poddubnyy, Thomas Schneider Tags: Case Report Source Type: research

Adsorption characteristics of ciprofloxacin hydrochloride on polystyrene microplastics in freshwater
Environ Sci Pollut Res Int. 2024 Mar 4. doi: 10.1007/s11356-024-32750-y. Online ahead of print.ABSTRACTIn order to reveal the adsorption mechanism of microplastics (MPs) on antibiotics, polystyrene (PS) was chosen as a typical microplastic, Fenton and high-temperature aging methods were used to obtain aged MPs particles. The adsorption behavior and mechanism of ciprofloxacin hydrochloride (CIP) on PS before and after aging were studied by batch adsorption experiments, and other influencing environmental conditions were evaluated concurrently. The results showed that the adsorption of CIP on PS was an exothermic reaction, t...
Source: Environmental Science and Pollution Research International - March 4, 2024 Category: Environmental Health Authors: Xi Gao Silu Chang Fengxu Liu Jiayu Wei Bo Yan Source Type: research

Isolation, Identification, Antimicrobial Resistance, Genotyping, and Whole-Genome Sequencing Analysis of < em > Salmonella < /em > Enteritidis Isolated from a Food-Poisoning Incident
Pol J Microbiol. 2024 Mar 4;73(1):69-89. doi: 10.33073/pjm-2024-008. eCollection 2024 Mar 1.ABSTRACTSalmonella enterica is a common pathogen in humans and animals that causes food poisoning and infection, threatening public health safety. We aimed to investigate the genome structure, drug resistance, virulence characteristics, and genetic relationship of a Salmonella strain isolated from patients with food poisoning. The pathogen strain 21A was collected from the feces of patients with food poisoning, and its minimum inhibitory concentration against commonly used antibiotics was determined using the strip test and Kirby-Ba...
Source: Polish Journal of Microbiology - March 4, 2024 Category: Microbiology Authors: Zhuru Hou Benjin Xu Ling Liu Rongrong Yan Jinjing Zhang Source Type: research

Isolation, Identification, Antimicrobial Resistance, Genotyping, and Whole-Genome Sequencing Analysis of < em > Salmonella < /em > Enteritidis Isolated from a Food-Poisoning Incident
Pol J Microbiol. 2024 Mar 4;73(1):69-89. doi: 10.33073/pjm-2024-008. eCollection 2024 Mar 1.ABSTRACTSalmonella enterica is a common pathogen in humans and animals that causes food poisoning and infection, threatening public health safety. We aimed to investigate the genome structure, drug resistance, virulence characteristics, and genetic relationship of a Salmonella strain isolated from patients with food poisoning. The pathogen strain 21A was collected from the feces of patients with food poisoning, and its minimum inhibitory concentration against commonly used antibiotics was determined using the strip test and Kirby-Ba...
Source: Polish Journal of Microbiology - March 4, 2024 Category: Microbiology Authors: Zhuru Hou Benjin Xu Ling Liu Rongrong Yan Jinjing Zhang Source Type: research