Mesenchymal stem cell-based adjunctive therapy for Pseudomonas aeruginosa-induced keratitis: A proof-of-concept in-vitro
CONCLUSION: MSC-CM holds promise as an adjunctive therapeutic approach for P. aeruginosa-induced corneal epithelial damage.PMID:38494102 | DOI:10.1016/j.exer.2024.109863 (Source: Experimental Eye Research)
Source: Experimental Eye Research - March 17, 2024 Category: Opthalmology Authors: Sreya Mitra Vasudeva Tati Prabhudatta Das Joveeta Joseph Bhupesh Bagga Sachin Shukla Source Type: research
Effect of ciprofloxacin on the one-stage partial nitrification and anammox biofilm system: A multivariate analysis focusing on size-fractionated organic components
Chemosphere. 2024 Mar 15:141731. doi: 10.1016/j.chemosphere.2024.141731. Online ahead of print.ABSTRACTThe impact of ciprofloxacin (CIP) in the partial nitrification and anammox biofilm system was investigated by multivariate analysis, focusing on size-fractionated organic components. The CIP dose of 10 μg/L did not inhibit the total nitrogen (TN) removal efficiency, even though the abundance of antibiotic resistant genes (ARGs) (i.e., qnrD, qnrB, qnrA, qnrS, and arcA) was elevated. However, a gradual higher CIP dosing up to 100 μg/L inhibited the TN removal efficiency, while the abundance of ARGs was still increased. Mo...
Source: Chemosphere - March 17, 2024 Category: Chemistry Authors: Keke Xiao Gudrun Abbt-Braun Robert Pleitner Harald Horn Source Type: research
Effect of ciprofloxacin on the one-stage partial nitrification and anammox biofilm system: A multivariate analysis focusing on size-fractionated organic components
Chemosphere. 2024 Mar 15:141731. doi: 10.1016/j.chemosphere.2024.141731. Online ahead of print.ABSTRACTThe impact of ciprofloxacin (CIP) in the partial nitrification and anammox biofilm system was investigated by multivariate analysis, focusing on size-fractionated organic components. The CIP dose of 10 μg/L did not inhibit the total nitrogen (TN) removal efficiency, even though the abundance of antibiotic resistant genes (ARGs) (i.e., qnrD, qnrB, qnrA, qnrS, and arcA) was elevated. However, a gradual higher CIP dosing up to 100 μg/L inhibited the TN removal efficiency, while the abundance of ARGs was still increased. Mo...
Source: Chemosphere - March 17, 2024 Category: Chemistry Authors: Keke Xiao Gudrun Abbt-Braun Robert Pleitner Harald Horn Source Type: research
Mesenchymal stem cell-based adjunctive therapy for Pseudomonas aeruginosa-induced keratitis: A proof-of-concept in-vitro
CONCLUSION: MSC-CM holds promise as an adjunctive therapeutic approach for P. aeruginosa-induced corneal epithelial damage.PMID:38494102 | DOI:10.1016/j.exer.2024.109863 (Source: Experimental Eye Research)
Source: Experimental Eye Research - March 17, 2024 Category: Opthalmology Authors: Sreya Mitra Vasudeva Tati Prabhudatta Das Joveeta Joseph Bhupesh Bagga Sachin Shukla Source Type: research
Mesenchymal stem cell-based adjunctive therapy for Pseudomonas aeruginosa-induced keratitis: A proof-of-concept in-vitro
CONCLUSION: MSC-CM holds promise as an adjunctive therapeutic approach for P. aeruginosa-induced corneal epithelial damage.PMID:38494102 | DOI:10.1016/j.exer.2024.109863 (Source: Experimental Eye Research)
Source: Experimental Eye Research - March 17, 2024 Category: Opthalmology Authors: Sreya Mitra Vasudeva Tati Prabhudatta Das Joveeta Joseph Bhupesh Bagga Sachin Shukla Source Type: research
Efficient removal of ciprofloxacin and ofloxacin from aqueous solutions using a novel nano-scale adsorbent: Modeling, optimization, and characterization
Chemosphere. 2024 Mar 14:141640. doi: 10.1016/j.chemosphere.2024.141640. Online ahead of print.ABSTRACTIn the fascinating realm of water purification, our study unveils the remarkable potential of a cutting-edge nano-scale adsorbent-combining graphene oxide (GO), chitosan (CS), and polydopamine (PDA)-in efficiently remove ciprofloxacin (CPF) and ofloxacin (OFL) from aqueous solutions. Our exploration delves deep into the adsorbent's character, utilizing a range of analytical techniques including SEM, RAMAN, FTIR, TGA, BET, XRD, and Zeta potential analyses provided insights into the adsorbent's properties. Modeling the adso...
Source: Chemosphere - March 16, 2024 Category: Chemistry Authors: Omid Farzinmanesh Mina Hosseini Sabzevari Mohammad Reza Asghari Source Type: research
Efficient removal of ciprofloxacin and ofloxacin from aqueous solutions using a novel nano-scale adsorbent: Modeling, optimization, and characterization
Chemosphere. 2024 Mar 14:141640. doi: 10.1016/j.chemosphere.2024.141640. Online ahead of print.ABSTRACTIn the fascinating realm of water purification, our study unveils the remarkable potential of a cutting-edge nano-scale adsorbent-combining graphene oxide (GO), chitosan (CS), and polydopamine (PDA)-in efficiently remove ciprofloxacin (CPF) and ofloxacin (OFL) from aqueous solutions. Our exploration delves deep into the adsorbent's character, utilizing a range of analytical techniques including SEM, RAMAN, FTIR, TGA, BET, XRD, and Zeta potential analyses provided insights into the adsorbent's properties. Modeling the adso...
Source: Chemosphere - March 16, 2024 Category: Chemistry Authors: Omid Farzinmanesh Mina Hosseini Sabzevari Mohammad Reza Asghari Source Type: research
Efficient removal of ciprofloxacin and ofloxacin from aqueous solutions using a novel nano-scale adsorbent: Modeling, optimization, and characterization
Chemosphere. 2024 Mar 14:141640. doi: 10.1016/j.chemosphere.2024.141640. Online ahead of print.ABSTRACTIn the fascinating realm of water purification, our study unveils the remarkable potential of a cutting-edge nano-scale adsorbent-combining graphene oxide (GO), chitosan (CS), and polydopamine (PDA)-in efficiently remove ciprofloxacin (CPF) and ofloxacin (OFL) from aqueous solutions. Our exploration delves deep into the adsorbent's character, utilizing a range of analytical techniques including SEM, RAMAN, FTIR, TGA, BET, XRD, and Zeta potential analyses provided insights into the adsorbent's properties. Modeling the adso...
Source: Chemosphere - March 16, 2024 Category: Chemistry Authors: Omid Farzinmanesh Mina Hosseini Sabzevari Mohammad Reza Asghari Source Type: research
Efficient removal of ciprofloxacin and ofloxacin from aqueous solutions using a novel nano-scale adsorbent: Modeling, optimization, and characterization
Chemosphere. 2024 Mar 14:141640. doi: 10.1016/j.chemosphere.2024.141640. Online ahead of print.ABSTRACTIn the fascinating realm of water purification, our study unveils the remarkable potential of a cutting-edge nano-scale adsorbent-combining graphene oxide (GO), chitosan (CS), and polydopamine (PDA)-in efficiently remove ciprofloxacin (CPF) and ofloxacin (OFL) from aqueous solutions. Our exploration delves deep into the adsorbent's character, utilizing a range of analytical techniques including SEM, RAMAN, FTIR, TGA, BET, XRD, and Zeta potential analyses provided insights into the adsorbent's properties. Modeling the adso...
Source: Chemosphere - March 16, 2024 Category: Chemistry Authors: Omid Farzinmanesh Mina Hosseini Sabzevari Mohammad Reza Asghari Source Type: research
Integrating target-responsive microfluidic-based biosensing chip with smartphone for simultaneous quantification of multiple fluoroquinolones
In this study, the background-free properties of upconversion nanoparticles (UCNPs), the high specificity of the target aptamer (Apt), and the high quenching properties of graphene oxide (GO) were integrated into a microfluidic-based fluorescence biosensing chip (MFBC). Interestingly, the microfluidic channels of the MFBC were prepared by laser-printing technology without the need for complex preparation processes and additional specialized equipment. The target-responsive fluorescence biosensing probes loaded on the MFBC were prepared by self-assembly of the UCNPs-Apt complex with GO based on π-π stacking interactions, ...
Source: Biosensors and Bioelectronics - March 15, 2024 Category: Biotechnology Authors: Mingming Zhang Xue Wang Shuangshuang Liu Tahreem Riaz Quansheng Chen Qin Ouyang Source Type: research
Exploring variations in recommended first ‐choice therapy for complicated urinary tract infections in males: Insights from outpatient settings across age, race, and ethnicity
ConclusionsNearly half of the patients included in this study did not receive recommended first-choice therapies; however, racial and ethnic disparities were not identified. Underutilization of recommended first-choice antibiotic therapy in complicated UTIs continues to be an area of focus for antimicrobial stewardship programs. (Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - March 14, 2024 Category: Drugs & Pharmacology Authors: Kathryn Sine,
Thomas Lavoie,
Aisling R. Caffrey,
Vrishali V. Lopes,
David Dosa,
Kerry L. LaPlante,
Haley J. Appaneal Tags: RESEARCH ARTICLE Source Type: research
Antibacterial and Antioxidant Efficacies of Secondary Metabolites from the Roots of < em > Cyphostemma adenocaule < /em > : A Combined < em > In Vitro < /em > and < em > In Silico < /em > Study
J Trop Med. 2024 Mar 6;2024:1679695. doi: 10.1155/2024/1679695. eCollection 2024.ABSTRACTCyphostemma adenocaule is a therapeutic plant traditionally used to treat rabies, snake bite, diarrhea, and wound healing. To address the bioactive compounds exhibiting these activities, we performed a comprehensive study on the roots of the plant. Thus, the present study aims to inspect the in vitro antioxidant and antibacterial efficacies of compounds isolated from the combined dichloromethane : methanol (1 : 1) and methanol extracts of C. adenocaule along with the in silico study of their interaction with selected protein targets. T...
Source: Molecular Medicine - March 14, 2024 Category: Molecular Biology Authors: Hadush Gebrehiwot Yadessa Melaku Muhdin Aliye Urgessa Ensermu Aman Dekebo Milkyas Endale Daniel Rentsch Mo Hunsen Source Type: research
Antibacterial and Antioxidant Efficacies of Secondary Metabolites from the Roots of < em > Cyphostemma adenocaule < /em > : A Combined < em > In Vitro < /em > and < em > In Silico < /em > Study
J Trop Med. 2024 Mar 6;2024:1679695. doi: 10.1155/2024/1679695. eCollection 2024.ABSTRACTCyphostemma adenocaule is a therapeutic plant traditionally used to treat rabies, snake bite, diarrhea, and wound healing. To address the bioactive compounds exhibiting these activities, we performed a comprehensive study on the roots of the plant. Thus, the present study aims to inspect the in vitro antioxidant and antibacterial efficacies of compounds isolated from the combined dichloromethane : methanol (1 : 1) and methanol extracts of C. adenocaule along with the in silico study of their interaction with selected protein targets. T...
Source: Journal of Tropical Medicine - March 14, 2024 Category: Tropical Medicine Authors: Hadush Gebrehiwot Yadessa Melaku Muhdin Aliye Urgessa Ensermu Aman Dekebo Milkyas Endale Daniel Rentsch Mo Hunsen Source Type: research
On-site extraction using a 3D printed device coated with Zn/Co-ZIF-derived carbon followed by an on-line SIA-HPLC-FL system for fluoroquinolones determination in wastewater
Talanta. 2024 Mar 11;273:125897. doi: 10.1016/j.talanta.2024.125897. Online ahead of print.ABSTRACTA 3D printed device covered with Zn/Co-ZIF-derived carbon allows the on-site extraction of fluoroquinolones (FQs) from wastewater, avoiding the sample transportation to the laboratory, and the subsequent elution, separation and determination using an on-line flow system based on sequential injection analysis (SIA) coupled to HPLC-FL. Several parameters that affect the extraction efficiency and desorption were optimized including the sorption phase immobilization technique on the 3D device, extraction time, pH effect, sample v...
Source: Talanta - March 14, 2024 Category: Chemistry Authors: D Barzallo A Est án N Cresp í C Palomino G Turnes E Palacio L Ferrer Source Type: research
