The Potential Role of < em > Gymnema inodorum < /em > Leaf Extract Treatment in Hematological Parameters in Mice Infected with < em > Plasmodium berghei < /em >
J Trop Med. 2021 Jun 28;2021:9989862. doi: 10.1155/2021/9989862. eCollection 2021.ABSTRACTMalaria remains a significant cause of death in tropical and subtropical regions by serious complications with hematological abnormalities consistent with high parasitemia. Hence, this study aimed to determine the efficacy of the Gymnema inodorum leaf extract (GIE) on hematological alteration in Plasmodium berghei infection in mice. Groups of ICR mice were infected intraperitoneally with parasitized red blood cells of P. berghei ANKA (PbANKA). They were administered orally by gavage of 100, 250, and 500 mg/kg of GIE for 4 consecutive ...
Source: Journal of Tropical Medicine - July 14, 2021 Category: Tropical Medicine Authors: Sakaewan Ounjaijean Suriyan Sukati Voravuth Somsak Orawan Sarakul Source Type: research

< em > In Vivo < /em > Antimalarial Activity of Leaf Latex of < em > Aloe melanacantha < /em > against < em > Plasmodium berghei < /em > Infected Mice
J Trop Med. 2021 Jun 21;2021:6690725. doi: 10.1155/2021/6690725. eCollection 2021.ABSTRACTBACKGROUND: Malaria is a major health concern in the world in general and developing countries in particular. Nowadays, the control of malaria has ended up steadily more complex due to the spread of drug-resistant parasites. Medicinal plants are the verifiable source of compelling antimalarial drugs. The present study was aimed to assess the in vivo antimalarial activity of leaf latex of A. melanacantha against Plasmodium berghei in mice.METHODS: Acute oral toxicity study of the leaf latex was assessed in mice up to a dose of 2,000 mg...
Source: Journal of Tropical Medicine - July 12, 2021 Category: Tropical Medicine Authors: Gebrehiwot Kiros Gebremariam Haile Kassahun Desta Tekleab Teka Teklehaimanot Tsgab Gebrecherkos Girmay Source Type: research

Cytokine Response Profiles of School-Aged Children Infected with Schistosomiasis before and after Praziquantel Treatment
The objective of this study was to evaluate the cytokine profiles of IL-4, IL-2, IL-10, IL-5, IFN-γ, and TNF in serum samples of infected school-aged children by using flow cytometry before and after treatment. The analysis indicated a shift in the expression of the cytokines after treatment with all the cytokines being downregulated, except TNF. There was a general trend of decrease in the expression of the cytokines at six and twelve weeks after treatment as compared to the pretreatment levels. There were statistically significant differences in the expression in IL-2 (P=0.001 ∗∗ ), IL-4 (P=0.033 &low...
Source: Journal of Tropical Medicine - July 9, 2021 Category: Tropical Medicine Authors: Edward Okonjo Dorcas Yole Dorington Ogoyi Source Type: research

Human Intestinal Parasites: Prevalence and Associated Risk Factors among Grade School Children in Maksegnit, Northwest Ethiopia
This study was aimed to assess the prevalence and associated risk factors of intestinal parasitic infections in grade school children in Maksegnit, Northwest Ethiopia. Five species of intestinal parasites were identified with an overall prevalence of 155 (40.4%). Among these, Ascaris lumbricoides 122 (31.8%) and Entamoeba histolytica 18 (4.7%) were predominant. Of the total 155 (40.4%) positive individuals, 149 (39%) had a single infection and the rest 6 (1.6%) had double parasitic infections. Of the different variables assessed, age, gender, shoe wearing, and eating raw or undercooked vegetables were not significantly ass...
Source: Journal of Tropical Medicine - July 5, 2021 Category: Tropical Medicine Authors: Kefale Shiferaw Teklemichael Tesfay Girmay Kalayu Gebrehiwot Kiros Source Type: research

Knowledge, Attitude, and Practices (KAP) of Human Populations towards Malaria Control in Four Ecoepidemiological Settings in Cameroon
J Trop Med. 2021 Jun 11;2021:9925135. doi: 10.1155/2021/9925135. eCollection 2021.ABSTRACTMalaria remains a major public health problem in Cameroon. Critical steps to improve disease control include assessing human population adherence to vector control interventions, especially in areas with different cultural backgrounds. The present study seeks to assess the knowledge, attitude, and practices (KAP) of populations towards malaria prevention in four ecoepidemiological settings in Cameroon. A cross-sectional malaria KAP survey was conducted from August to September 2019 in households of the localities of Kaélé...
Source: Journal of Tropical Medicine - July 5, 2021 Category: Tropical Medicine Authors: Nelly Armanda Kala Chouakeu Laura Gilberine Ngingahi Roland Bamou Abdou Talipouo Carmen Sandra Ngadjeu Marie Paul Audrey Mayi Edmond Kopya Parfait Awono-Ambene Timol éon Tchuinkam Christophe Antonio Nkondjio Source Type: research

Human Intestinal Parasites: Prevalence and Associated Risk Factors among Grade School Children in Maksegnit, Northwest Ethiopia
This study was aimed to assess the prevalence and associated risk factors of intestinal parasitic infections in grade school children in Maksegnit, Northwest Ethiopia. Five species of intestinal parasites were identified with an overall prevalence of 155 (40.4%). Among these, Ascaris lumbricoides 122 (31.8%) and Entamoeba histolytica 18 (4.7%) were predominant. Of the total 155 (40.4%) positive individuals, 149 (39%) had a single infection and the rest 6 (1.6%) had double parasitic infections. Of the different variables assessed, age, gender, shoe wearing, and eating raw or undercooked vegetables were not significantly ass...
Source: Journal of Tropical Medicine - July 5, 2021 Category: Tropical Medicine Authors: Kefale Shiferaw Teklemichael Tesfay Girmay Kalayu Gebrehiwot Kiros Source Type: research

Knowledge, Attitude, and Practices (KAP) of Human Populations towards Malaria Control in Four Ecoepidemiological Settings in Cameroon
J Trop Med. 2021 Jun 11;2021:9925135. doi: 10.1155/2021/9925135. eCollection 2021.ABSTRACTMalaria remains a major public health problem in Cameroon. Critical steps to improve disease control include assessing human population adherence to vector control interventions, especially in areas with different cultural backgrounds. The present study seeks to assess the knowledge, attitude, and practices (KAP) of populations towards malaria prevention in four ecoepidemiological settings in Cameroon. A cross-sectional malaria KAP survey was conducted from August to September 2019 in households of the localities of Kaélé...
Source: Journal of Tropical Medicine - July 5, 2021 Category: Tropical Medicine Authors: Nelly Armanda Kala Chouakeu Laura Gilberine Ngingahi Roland Bamou Abdou Talipouo Carmen Sandra Ngadjeu Marie Paul Audrey Mayi Edmond Kopya Parfait Awono-Ambene Timol éon Tchuinkam Christophe Antonio Nkondjio Source Type: research

Human Intestinal Parasites: Prevalence and Associated Risk Factors among Grade School Children in Maksegnit, Northwest Ethiopia
This study was aimed to assess the prevalence and associated risk factors of intestinal parasitic infections in grade school children in Maksegnit, Northwest Ethiopia. Five species of intestinal parasites were identified with an overall prevalence of 155 (40.4%). Among these, Ascaris lumbricoides 122 (31.8%) and Entamoeba histolytica 18 (4.7%) were predominant. Of the total 155 (40.4%) positive individuals, 149 (39%) had a single infection and the rest 6 (1.6%) had double parasitic infections. Of the different variables assessed, age, gender, shoe wearing, and eating raw or undercooked vegetables were not significantly ass...
Source: Journal of Tropical Medicine - July 5, 2021 Category: Tropical Medicine Authors: Kefale Shiferaw Teklemichael Tesfay Girmay Kalayu Gebrehiwot Kiros Source Type: research

Knowledge, Attitude, and Practices (KAP) of Human Populations towards Malaria Control in Four Ecoepidemiological Settings in Cameroon
J Trop Med. 2021 Jun 11;2021:9925135. doi: 10.1155/2021/9925135. eCollection 2021.ABSTRACTMalaria remains a major public health problem in Cameroon. Critical steps to improve disease control include assessing human population adherence to vector control interventions, especially in areas with different cultural backgrounds. The present study seeks to assess the knowledge, attitude, and practices (KAP) of populations towards malaria prevention in four ecoepidemiological settings in Cameroon. A cross-sectional malaria KAP survey was conducted from August to September 2019 in households of the localities of Kaélé...
Source: Journal of Tropical Medicine - July 5, 2021 Category: Tropical Medicine Authors: Nelly Armanda Kala Chouakeu Laura Gilberine Ngingahi Roland Bamou Abdou Talipouo Carmen Sandra Ngadjeu Marie Paul Audrey Mayi Edmond Kopya Parfait Awono-Ambene Timol éon Tchuinkam Christophe Antonio Nkondjio Source Type: research

Human Intestinal Parasites: Prevalence and Associated Risk Factors among Grade School Children in Maksegnit, Northwest Ethiopia
This study was aimed to assess the prevalence and associated risk factors of intestinal parasitic infections in grade school children in Maksegnit, Northwest Ethiopia. Five species of intestinal parasites were identified with an overall prevalence of 155 (40.4%). Among these, Ascaris lumbricoides 122 (31.8%) and Entamoeba histolytica 18 (4.7%) were predominant. Of the total 155 (40.4%) positive individuals, 149 (39%) had a single infection and the rest 6 (1.6%) had double parasitic infections. Of the different variables assessed, age, gender, shoe wearing, and eating raw or undercooked vegetables were not significantly ass...
Source: Journal of Tropical Medicine - July 5, 2021 Category: Tropical Medicine Authors: Kefale Shiferaw Teklemichael Tesfay Girmay Kalayu Gebrehiwot Kiros Source Type: research

Knowledge, Attitude, and Practices (KAP) of Human Populations towards Malaria Control in Four Ecoepidemiological Settings in Cameroon
J Trop Med. 2021 Jun 11;2021:9925135. doi: 10.1155/2021/9925135. eCollection 2021.ABSTRACTMalaria remains a major public health problem in Cameroon. Critical steps to improve disease control include assessing human population adherence to vector control interventions, especially in areas with different cultural backgrounds. The present study seeks to assess the knowledge, attitude, and practices (KAP) of populations towards malaria prevention in four ecoepidemiological settings in Cameroon. A cross-sectional malaria KAP survey was conducted from August to September 2019 in households of the localities of Kaélé...
Source: Journal of Tropical Medicine - July 5, 2021 Category: Tropical Medicine Authors: Nelly Armanda Kala Chouakeu Laura Gilberine Ngingahi Roland Bamou Abdou Talipouo Carmen Sandra Ngadjeu Marie Paul Audrey Mayi Edmond Kopya Parfait Awono-Ambene Timol éon Tchuinkam Christophe Antonio Nkondjio Source Type: research

Chemical Composition and In Vitro Evaluation of the Mosquito (Anopheles) Repellent Property of Neem ( < em > Azadirachta indica < /em > ) Seed Oil
J Trop Med. 2021 Jun 4;2021:5567063. doi: 10.1155/2021/5567063. eCollection 2021.ABSTRACTAs one of the killer diseases in the world, malaria contributes to child mortality and global death annually. As a result, many reactive mechanisms have evolved to control and repel mosquitoes. The use of synthetic mosquito repellents with N,N-Diethyl-meta-toluamide (DEET) is one of the popular interventions despite its dermatological limitations such as skin irritations. Ethnobotanical reviews have identified that the adoption of natural repellents promises high repellence on mosquitoes with minimal side effects compared with syntheti...
Source: Journal of Tropical Medicine - July 1, 2021 Category: Tropical Medicine Authors: Olive Aidoo Noble Kuntworbe Fredrick William Akuffo Owusu Deryl Nii Okantey Kuevi Source Type: research

Tuberculosis Treatment Outcome in Patients with TB-HIV Coinfection in Kuala Lumpur, Malaysia
This study aimed to identify the characteristics, unsuccessful TB treatment rate, and determinants of unsuccessful TB treatment outcome among patients with TB-HIV coinfection in Kuala Lumpur.METHODS: This was a cross-sectional study. The data of all patients with TB-HIV in the federal territory of Kuala Lumpur from 2013 to 2017 were collected and reviewed. The data were retrieved from the national database (TB Information System) at the Kuala Lumpur Health Department from 1 March 2018 to 31 May 2018.RESULTS: Out of 235 randomly selected patients with TB-HIV, TB treatment outcome was successful in 57.9% (cured and completed...
Source: Journal of Tropical Medicine - July 1, 2021 Category: Tropical Medicine Authors: Diana Safraa Selimin Aniza Ismail Norfazilah Ahmad Rohani Ismail Nurul Farhana Mohd Azman Amaleena Azman Source Type: research

Chemical Composition and In Vitro Evaluation of the Mosquito (Anopheles) Repellent Property of Neem ( < em > Azadirachta indica < /em > ) Seed Oil
J Trop Med. 2021 Jun 4;2021:5567063. doi: 10.1155/2021/5567063. eCollection 2021.ABSTRACTAs one of the killer diseases in the world, malaria contributes to child mortality and global death annually. As a result, many reactive mechanisms have evolved to control and repel mosquitoes. The use of synthetic mosquito repellents with N,N-Diethyl-meta-toluamide (DEET) is one of the popular interventions despite its dermatological limitations such as skin irritations. Ethnobotanical reviews have identified that the adoption of natural repellents promises high repellence on mosquitoes with minimal side effects compared with syntheti...
Source: Journal of Tropical Medicine - July 1, 2021 Category: Tropical Medicine Authors: Olive Aidoo Noble Kuntworbe Fredrick William Akuffo Owusu Deryl Nii Okantey Kuevi Source Type: research

Tuberculosis Treatment Outcome in Patients with TB-HIV Coinfection in Kuala Lumpur, Malaysia
This study aimed to identify the characteristics, unsuccessful TB treatment rate, and determinants of unsuccessful TB treatment outcome among patients with TB-HIV coinfection in Kuala Lumpur.METHODS: This was a cross-sectional study. The data of all patients with TB-HIV in the federal territory of Kuala Lumpur from 2013 to 2017 were collected and reviewed. The data were retrieved from the national database (TB Information System) at the Kuala Lumpur Health Department from 1 March 2018 to 31 May 2018.RESULTS: Out of 235 randomly selected patients with TB-HIV, TB treatment outcome was successful in 57.9% (cured and completed...
Source: Journal of Tropical Medicine - July 1, 2021 Category: Tropical Medicine Authors: Diana Safraa Selimin Aniza Ismail Norfazilah Ahmad Rohani Ismail Nurul Farhana Mohd Azman Amaleena Azman Source Type: research

Chemical Composition and In Vitro Evaluation of the Mosquito (Anopheles) Repellent Property of Neem ( < em > Azadirachta indica < /em > ) Seed Oil
J Trop Med. 2021 Jun 4;2021:5567063. doi: 10.1155/2021/5567063. eCollection 2021.ABSTRACTAs one of the killer diseases in the world, malaria contributes to child mortality and global death annually. As a result, many reactive mechanisms have evolved to control and repel mosquitoes. The use of synthetic mosquito repellents with N,N-Diethyl-meta-toluamide (DEET) is one of the popular interventions despite its dermatological limitations such as skin irritations. Ethnobotanical reviews have identified that the adoption of natural repellents promises high repellence on mosquitoes with minimal side effects compared with syntheti...
Source: Journal of Tropical Medicine - July 1, 2021 Category: Tropical Medicine Authors: Olive Aidoo Noble Kuntworbe Fredrick William Akuffo Owusu Deryl Nii Okantey Kuevi Source Type: research

Tuberculosis Treatment Outcome in Patients with TB-HIV Coinfection in Kuala Lumpur, Malaysia
This study aimed to identify the characteristics, unsuccessful TB treatment rate, and determinants of unsuccessful TB treatment outcome among patients with TB-HIV coinfection in Kuala Lumpur.METHODS: This was a cross-sectional study. The data of all patients with TB-HIV in the federal territory of Kuala Lumpur from 2013 to 2017 were collected and reviewed. The data were retrieved from the national database (TB Information System) at the Kuala Lumpur Health Department from 1 March 2018 to 31 May 2018.RESULTS: Out of 235 randomly selected patients with TB-HIV, TB treatment outcome was successful in 57.9% (cured and completed...
Source: Journal of Tropical Medicine - July 1, 2021 Category: Tropical Medicine Authors: Diana Safraa Selimin Aniza Ismail Norfazilah Ahmad Rohani Ismail Nurul Farhana Mohd Azman Amaleena Azman Source Type: research

Chemical Composition and In Vitro Evaluation of the Mosquito (Anopheles) Repellent Property of Neem ( < em > Azadirachta indica < /em > ) Seed Oil
J Trop Med. 2021 Jun 4;2021:5567063. doi: 10.1155/2021/5567063. eCollection 2021.ABSTRACTAs one of the killer diseases in the world, malaria contributes to child mortality and global death annually. As a result, many reactive mechanisms have evolved to control and repel mosquitoes. The use of synthetic mosquito repellents with N,N-Diethyl-meta-toluamide (DEET) is one of the popular interventions despite its dermatological limitations such as skin irritations. Ethnobotanical reviews have identified that the adoption of natural repellents promises high repellence on mosquitoes with minimal side effects compared with syntheti...
Source: Journal of Tropical Medicine - July 1, 2021 Category: Tropical Medicine Authors: Olive Aidoo Noble Kuntworbe Fredrick William Akuffo Owusu Deryl Nii Okantey Kuevi Source Type: research

Tuberculosis Treatment Outcome in Patients with TB-HIV Coinfection in Kuala Lumpur, Malaysia
This study aimed to identify the characteristics, unsuccessful TB treatment rate, and determinants of unsuccessful TB treatment outcome among patients with TB-HIV coinfection in Kuala Lumpur.METHODS: This was a cross-sectional study. The data of all patients with TB-HIV in the federal territory of Kuala Lumpur from 2013 to 2017 were collected and reviewed. The data were retrieved from the national database (TB Information System) at the Kuala Lumpur Health Department from 1 March 2018 to 31 May 2018.RESULTS: Out of 235 randomly selected patients with TB-HIV, TB treatment outcome was successful in 57.9% (cured and completed...
Source: Journal of Tropical Medicine - July 1, 2021 Category: Tropical Medicine Authors: Diana Safraa Selimin Aniza Ismail Norfazilah Ahmad Rohani Ismail Nurul Farhana Mohd Azman Amaleena Azman Source Type: research

Effect of Prior Symptomatic Dengue Infection on Dengue Haemorrhagic Fever (DHF) in Children
J Trop Med. 2021 Jun 2;2021:8842799. doi: 10.1155/2021/8842799. eCollection 2021.ABSTRACTPathogenesis of dengue haemorrhagic fever is not fully understood, but it is thought that there is antibody enhancement during the secondary infection, which causes severe dengue haemorrhagic fever (DHF). Therefore, patients who have DHF should have a documented history of symptomatic dengue infection in the past. A retrospective descriptive-analytical study was conducted at the University Paediatric Unit at Lady Ridgeway Hospital for Children, Colombo, Sri Lanka. All children who had fulfilled the criteria for DHF admitted to the unit...
Source: Journal of Tropical Medicine - June 14, 2021 Category: Tropical Medicine Authors: Randula Ranawaka Chamara Jayamanne Kavinda Dayasiri Dinuka Samaranayake Udara Sandakelum Wathsala Hathagoda Ruwangi Dissanayake Pujitha Wickramasinghe Source Type: research

Determination of Seroprevalence and Risk Factors of Crimean-Congo Haemorrhagic Fever (CCHF) in the Endemic Region in Turkey: A Population-Based Cross-Sectional Study
J Trop Med. 2021 May 17;2021:9945089. doi: 10.1155/2021/9945089. eCollection 2021.ABSTRACTOBJECTIVES: Turkey is one of the countries that has the most cases of CCHF in recent years among the endemic countries. The disease also poses an important health threat with high mortality rate. The aim of the study was to determine the seroprevalence and risk factors of CCHF in adults aged ≥20 years in Tokat in the endemic region, Turkey.METHODS: In this population-based cross-sectional study, a total of 85 Family Medicine Units (FMUs), from over 170 in Tokat, were randomly selected using 50% sampling. The sample size was determi...
Source: Journal of Tropical Medicine - May 31, 2021 Category: Tropical Medicine Authors: R ıza Çıtıl M ücahit Eğri Yal çın Önder Fazilet Duygu Yunus Emre Bulut Özkan Yaşayancan Nagehan Y ıldız Çeltek Şafak Şahin Source Type: research