Reproductive-Age Women's Knowledge and Care Seeking for Malaria Prevention and Control in Ghana: Analysis of the 2016 Malaria Indicator Survey.
Conclusion: Though ownership of ITNs and knowledge of malaria prevention were high, it did not necessarily translate into use of ITNs. Thus, there is a need to intensify education on the importance and the role of ITNs use in the prevention of malaria. PMID: 30891071 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - March 22, 2019 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Role of Plasmapheresis and Extracorporeal Membrane Oxygenation in the Treatment of Leptospirosis Complicated with Pulmonary Hemorrhages.
Conclusions: Current evidence is insufficient to recommend the routine use of plasmapheresis or ECMO for patients presenting with pulmonary hemorrhages due to leptospirosis. ECMO may be a promising mode of treatment in acute respiratory failure in leptospirosis related pulmonary hemorrhages. These treatment modalities, however, can be applied based on the availability of resources and expertise at the discretion of the clinician in charge, considering patient related factors such as cardiovascular stability and derangement of coagulation profile. Clinical trials conducted adhering to standard procedures are urgently requir...
Source: Journal of Tropical Medicine - January 13, 2019 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Regular Antenatal Attendance and Education Influence the Uptake of Intermittent Preventive Treatment of Malaria in Pregnancy: A Cross-Sectional Study at the University Hospital, Kumasi, Ghana.
This study evaluated the factors influencing uptake of IPTp-SP among pregnant women in Kumasi, Ghana. Methodology: This cross-sectional study was conducted among 280 pregnant women attending the Kwame Nkrumah University of Science and Technology Hospital in Kumasi, Ghana. Validated structured questionnaires were administered to obtain sociodemographic, medical/reproductive information, and IPTp-SP uptake among participants. Statistical analyses were performed using IBM SPSS 25.0 statistics. Results: The mean age of respondents was 29.7±4.9 years. Of the 280 women interviewed, 74.6% attended the antenatal car...
Source: Journal of Tropical Medicine - January 13, 2019 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Antimalarial Activity of Piperine.
Authors: Thiengsusuk A, Muhamad P, Chaijaroenkul W, Na-Bangchang K Abstract Malaria remains a public health problem in tropical and subtropical regions. Resistance of Plasmodium falciparum to artemisinins in Southeast Asia is a great concern for disease control and research on discovery and development of new alternative antimalarial drugs is urgently required. In a previous study, the fruit of Piper chaba Hunt. was demonstrated to exhibit promising antimalarial activity against the asexual stage of 3D7 (chloroquine-sensitive) and K1 (chloroquine-resistant) P. falciparum clones. The aim of the present study was to ...
Source: Journal of Tropical Medicine - January 13, 2019 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Biological Control of Mosquito-Borne Diseases: The Potential of Wolbachia-Based Interventions in an IVM Framework.
Authors: Niang EHA, Bassene H, Fenollar F, Mediannikov O Abstract People living in the tropical and subtropical regions of the world face an enormous health burden due to mosquito-borne diseases such as malaria, dengue fever, and filariasis. Historically and today, targeting mosquito vectors with, primarily, insecticide-based control strategies have been a key control strategy against major mosquito-borne diseases. However, the success to date of such approaches is under threat from multiple insecticide resistance mechanisms while vector control (VC) options are still limited. The situation therefore requires the d...
Source: Journal of Tropical Medicine - December 26, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Coinfections between Persistent Parasitic Neglected Tropical Diseases and Viral Infections among Prisoners from Sub-Saharan Africa and Latin America.
Authors: Da Silva Santos L, Wolff H, Chappuis F, Albajar-Viñas P, Vitoria M, Tran NT, Baggio S, Togni G, Vuilleumier N, Girardin F, Negro F, Gétaz L Abstract In Swiss prisons, more than 70% of detained people are foreigners and over one-third originate from sub-Saharan Africa or Latin America. These two regions are endemic for various tropical diseases and viral infections, which persist after migration to nonendemic countries. Parasitic infections (schistosomiasis; strongyloidiasis) and cooccurrent viral infections (HIV, hepatitis B (HBV), and hepatitis C (HCV)) are especially of concern for clinical...
Source: Journal of Tropical Medicine - December 14, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Isolation of Helicobacter pylori from Gastric Biopsy of Dyspeptic Patients in Ghana and In Vitro Preliminary Assessment of the Effect of Dissotis rotundifolia Extract on Its Growth.
This study sought to isolate H. pylori, from gastric biopsy samples of dyspeptic patients in Ghana using a 2,3,5-triphenyltetrazolium chloride (TTC) dye incorporated medium method. This TTC dye method was further used in an antimicrobial susceptibility assay involving Dissotis rotundifolia extract (DRE). H. pylori were successfully isolated from gastric biopsy of dyspeptic patients. Pure cultures of H. pylori in 2,3,5-triphenyltetrazolium chloride (TTC) dye incorporated medium were seen as sparkling colonies. Isolates, identified as H. pylori, were gram-negative and urease, catalase, and oxidase positive and showed charact...
Source: Journal of Tropical Medicine - December 6, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Trends for Diarrhea Morbidity in the Jasikan District of Ghana: Estimates from District Level Diarrhea Surveillance Data, 2012-2016.
This study analyzed the trends of diarrhea morbidity outcomes in the Jasikan District of Ghana. A retrospective analysis of records on diarrhea data for a five years' period (January 2012 to December 2016) was undertaken. There was a total of 17740 diarrhea case reports extracted from District Health Information Management System (DHIMS) II database in an Excel format which was then exported to Stata version 14 for data cleaning, verification, and analysis. Excel version 2016 was used to plot the actual observed cases by years to assess trends and seasonality. There was a period incidence rate of 272.02 per 1000 persons wi...
Source: Journal of Tropical Medicine - November 9, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Palliative Care in Congenital Syndrome of the Zika Virus Associated with Hospitalization and Emergency Consultation: Palliative Care and Congenital Syndrome of Zika.
Conclusions: For the patient with known severe malformations caused by congenital infection by the Zika virus with indication of palliative care, this approach could be used in order to allow life without suffering and disproportionate invasive method. PMID: 30405727 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - November 9, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Remote Supervision in Short-Term Global Health Experiences.
Authors: Relan P, Yiu KCY, Lin HC, Loh LC Abstract The global health development community is increasingly examining the phenomenon of short-term experiences in global health (STEGH), with an aim to mitigate the negative impacts of such activities on host communities. Appropriate supervision is one strategy, but various barriers (e.g., institutional requirements) limit the availability of qualified supervisors. Remote supervision represents one potential model to provide supervision that may mitigate the negative impacts of STEGH. This paper reports observed outcomes from a description of a pilot remote supervision...
Source: Journal of Tropical Medicine - October 30, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Prevalence of Human Bocavirus in Africa and Other Developing Countries between 2005 and 2016: A Potential Emerging Viral Pathogen for Diarrhea.
Conclusion: Reports suggest that HBoV infections are increasingly being recognized worldwide. Therefore, surveillance of individuals suffering from infections in Africa is required to monitor the prevalence of HBoV and help understand the role of HBoV in individuals suffering from gastroenteritis with/without respiratory tract infection. PMID: 30275840 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - October 3, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

A Cross-Sectional Study to Assess Capacity of Health Facility Laboratories in Zone One of Afar Regional State, Ethiopia.
Authors: Genet Akal C, Andualem T Abstract Role of laboratory service in patient care is well recognized in developed compared to developing countries like Ethiopia where most medical decisions are based on clinical judgment. Laboratory based medical decisions save life and resources. Thus, health facilities (HFs) having capacitated laboratories provide better health care service. Thus, this study assessed capacity of laboratories found in all nine HFs in zone one of Afar region, Ethiopia. Cross-sectional study was conducted from January to May 2015. Data were collected using questioner from medical laboratory prof...
Source: Journal of Tropical Medicine - September 5, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Developing Small Molecule Therapeutics for the Initial and Adjunctive Treatment of Snakebite.
Authors: Bulfone TC, Samuel SP, Bickler PE, Lewin MR Abstract The World Health Organization (WHO) recently added snakebite envenoming to the priority list of Neglected Tropical Diseases (NTD). It is thought that ~75% of mortality following snakebite occurs outside the hospital setting, making the temporal gap between a bite and antivenom administration a major therapeutic challenge. Small molecule therapeutics (SMTs) have been proposed as potential prereferral treatments for snakebite to help address this gap. Herein, we discuss the characteristics, potential uses, and development of SMTs as potential treatments fo...
Source: Journal of Tropical Medicine - August 30, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Interferon- γ and Interleukin-10 Responses during Clinical Malaria Episodes in Infants Aged 0-2 Years Prenatally Exposed to Plasmodium falciparum: Tanzanian Birth Cohort.
Conclusions: Prenatal exposure to P. falciparum antigens significantly affects IL-10 and IFN-γ responses during clinical malaria episodes in the first two years of life. PMID: 30154871 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - August 30, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Asymptomatic Plasmodium Parasites among Adults in Eastern Uganda: A Case of Donor Blood Screening at Mbale Regional Blood Bank.
Conclusion: The 1.3% prevalence of Plasmodium malaria parasites in screened donor blood units represents risk of malaria blood transfusion transmitted infection and a pool of community transmittable malaria infections, respectively. PMID: 30112007 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - August 17, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Amoebic Liver Abscess and Indigenous Alcoholic Beverages in the Tropics.
Authors: Kumanan T, Sujanitha V, Balakumar S, Sreeharan N Abstract Amoebic liver abscess (ALA) seen commonly in the tropics is predominantly confined to adult males, especially those who consume locally brewed alcohol, although intestinal amoebiasis occurs in all age groups and in both genders. Whether the role of alcohol in the development of ALA is incidental and casual or whether alcohol is causally implicated has been debated. It has been argued that socioeconomic factors and poor sanitary conditions are the primary culprits that casually link alcohol to ALA. However, there has emerged an abundance of data that...
Source: Journal of Tropical Medicine - August 17, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Patients' Knowledge of Artemisinin-Based Combination Therapy Treatment and Its Impact on Patient Adherence.
This study aimed to assess patients' knowledge of antimalarial treatment (ACT) and its association with patient adherence. A descriptive cross-sectional study design was employed in this study. Data were collected from April to May 2017. Both descriptive and inferential statistics in the form of frequencies, percentages, mean values, standard deviations, and Pearson's chi-square test were generated by use of Microsoft excel spreadsheet and IBM Statistical Package for Social Sciences (SPSS) version 23. The average age of the respondents surveyed for this study was 42.27 ± 11.09. Adherence level to ACT was 47%. The re...
Source: Journal of Tropical Medicine - August 16, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Assessing the Influence of Water Management and Rainfall Seasonality on Water Quality and Intestinal Parasitism in Rural Northeastern Brazil.
Conclusions: Data suggest that the strategies to increase water supply in the Brazilian semiarid region can be ameliorated in order to improve the quality of drinking water. PMID: 30105057 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - August 16, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Dog Bites and Rabies in the Eastern Region of Ghana in 2013-2015: A Call for a One-Health Approach.
Conclusion: Rabies remains an important cause of preventable deaths in this region. An integrated approach to surveillance based on the One-Health concept needs to be adopted. PMID: 30057629 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - July 31, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Low Frequency of Asymptomatic and Submicroscopic Plasmodial Infections in Urab á Region in Colombia.
Conclusion: Plasmodial afebrile infection was found in 2% of the studied population, by three diagnostic methods, in residents from a low endemic malaria region in Colombia. PMID: 30057630 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - July 31, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

An Analysis of a Dengue Outbreak at a Large Hospital and Epidemiological Evidence for Nosocomial Dengue.
Authors: Ehelepola NDB, Wijesinghe WMCM Abstract Reports on dengue outbreaks at hospitals are extremely rare. Here the authors analyze a dengue outbreak at the Teaching Hospital-Kandy (THK), Sri Lanka. Our hypothesis was that the present outbreak of dengue was due to nosocomial infections. Our objectives were to illustrate epidemiological evidence for nosocomial dengue infections among THK workers and comparison of dengue incidence of hospital workers of wards that treat dengue patients with workers of other wards, to ascertain whether most nosocomial dengue incidences occur closer to where dengue patients are trea...
Source: Journal of Tropical Medicine - July 28, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

The Use of Insecticide-Treated Curtains for Control of Aedes aegypti and Dengue Virus Transmission in "Fraccionamiento" Style Houses in M éxico.
The Use of Insecticide-Treated Curtains for Control of Aedes aegypti and Dengue Virus Transmission in "Fraccionamiento" Style Houses in México. J Trop Med. 2018;2018:4054501 Authors: Loroño-Pino MA, Uitz-Mena A, Carrillo-Solís CM, Zapata-Gil RJ, Camas-Tec DM, Talavera-Aguilar LG, Cetina-Trejo RC, Flores-Flores LF, Puc-Tinal MC, Caamal-Jiménez C, Reyes-Solís G, García-Rejón JE, Saavedra-Rodriguez K, Eisen L, Keefe TJ, Black Iv WC, Beaty BJ Abstract Dengue, chikungunya, yellow fever, and Zika viruses transmitted by Aedes aegypti mosquitoes are ma...
Source: Journal of Tropical Medicine - July 20, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

The Epidemiology of Human Immunodeficiency Virus (HIV) and Syphilis in Ghana: A Five-Year Single Urban Site Parallel Population-Based Analysis vis- à-vis the Sentinel Survey.
The Epidemiology of Human Immunodeficiency Virus (HIV) and Syphilis in Ghana: A Five-Year Single Urban Site Parallel Population-Based Analysis vis-à-vis the Sentinel Survey. J Trop Med. 2018;2018:6574731 Authors: Osei-Yeboah J, Lokpo SY, Ussher FA, Orish VN, Hamid AM, Dakorah MP, Ntoni T, Nani EA, Ayroe F, Adigbli D Abstract The study was aimed at comparing the estimation of the burden and trends (2012-2016) of Human Immunodeficiency Virus (HIV) and Syphilis infections by the national Sentinel Survey vis-à-vis the use of population-based studies at a single urban site (Municipal Hospital)...
Source: Journal of Tropical Medicine - July 14, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Cytokine Secretion of Peripheral Blood Mononuclear Cells by Hydnocarpus anthelminthicus Seeds.
Conclusions: Extracts of H. anthelminthicus seeds demonstrated various effects on the proinflammatory cytokine secretion of PBMCs. The application of these extracts should depend on the immune response of the host, which determines the manifestation of the disease. PMID: 29973956 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - July 7, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Presence of Rickettsia Species in a Marginalized Area of Yucatan, Mexico.
Authors: Peniche-Lara G, Jimenez-Delgadillo B, Munoz-Zanzi C, Cárdenas-Marrufo M, Pérez-Osorio C, Arias-León J Abstract In the state of Yucatan, Mexico, rickettsiosis has become a common vector-borne disease in the general population. Ectoparasite species such as Rhipicephalus sanguineus and Amblyomma mixtum have been identified as Rickettsia vectors in Yucatan by studies focused on the wild animal population in rural areas. There have been studies that have tried to determine the presence of Rickettsia species in ectoparasites collected in Yucatan, but these studies did not include marginalize...
Source: Journal of Tropical Medicine - July 7, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Risk Factors for Hemorrhagic and Ischemic Stroke in Sub-Saharan Africa.
Conclusions: There remain too few data from SSA to reliably estimate the effect of various factors on the risk of IS and HS. Furthermore, the vast majority of cases were identified in hospital and so are unlikely to be representative of the totality of stroke cases in the community. PMID: 29955233 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - July 1, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Quality Assessment of Some Essential Children's Medicines Sold in Licensed Outlets in Ashanti Region, Ghana.
Authors: Frimpong G, Ofori-Kwakye K, Kuntworbe N, Buabeng KO, Osei YA, Boakye-Gyasi ME, Adi-Dako O Abstract The quality of 68 samples of 15 different essential children's medicines sold in licensed medicine outlets in the Ashanti Region, Ghana, was evaluated. Thirty-two (47.1%) of the medicines were imported, mainly from India (65.6%) and the United Kingdom (28.1%), while 36 (52.9%) were locally manufactured. The quality of the medicines was assessed using content of active pharmaceutical ingredient (API), pH, and microbial limit tests, and the results were compared with pharmacopoeial standards. Twenty-six (38.2%)...
Source: Journal of Tropical Medicine - June 30, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

The Cross-Sectional Evaluation of the Use of Artemisinin-Based Combination Therapy for Treatment of Malaria Infection at a Tertiary Hospital in Nigeria.
This study aims to evaluate prescribers' adherence with the National Antimalarial Treatment Guideline (NATG) in the treatment of malaria infections and to describe the determinants of antimalarial drugs coprescription with antibiotics at a tertiary hospital in Nigeria. A cross-sectional, retrospective study of antimalarial drug prescriptions of one-year period of 2013 was conducted. A simple method for assessing the quality of drug prescribing (DU90%) was adopted. Logistic regression was used to predict antimalarial drugs coprescription with antibiotics. Overall, 95.8% of the total prescriptions contained ACTs, out of whic...
Source: Journal of Tropical Medicine - June 13, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Lymphatic Endothelial Cell in Endemic Bancroftian Filariasis: A Focus on the Lymphatics of the Tunica Vaginalis Testis.
Conclusion: The data suggest that LECs have an active role in the pathogenesis of bancroftian hydrocele and, possibly, in other clinical forms of lymphatic filariasis. PMID: 29861747 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - June 6, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Asymptomatic Leishmania Infected Children: A Seroprevalence and Molecular Survey in a Rural Area of Fars Province, Southern Iran.
Authors: Layegh Gigloo A, Sarkari B, Rezaei Z, Hatam GR, Davami MH Abstract The current study aimed to evaluate the seroprevalence of visceral leishmaniasis in asymptomatic healthy children in a rural area of Fars province, Southern Iran. Blood samples were taken from 617 asymptomatic healthy children and serum samples along with buffy coat were separated from the blood. The serum samples were assessed for antibodies against Leishmania infantum by an indirect ELISA and the buffy coats were tested for the presence of L. infantum DNA by molecular method. Of the 617 recruited children, 297 (48.1%) were female and 317 ...
Source: Journal of Tropical Medicine - June 6, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Urogenital Schistosomiasis among Schoolchildren and the Associated Risk Factors in Selected Rural Communities of Kwara State, Nigeria.
Authors: Abdulkareem BO, Habeeb KO, Kazeem A, Adam AO, Samuel UU Abstract Urogenital schistosomiasis is a chronic parasitic disease that causes severe morbidity among schoolchildren in many poor-resource communities in Nigeria. We investigated the prevalence, intensity, and risk factors of the infection in three communities of Kwara State to ascertain the current status of the disease. Of the 724 urine samples screened, using filtration method, 332 (45.6%) school-aged children were infected with average intensity and mean population eggs load of 127.9 eggs/10 ml of urine and 0.794, respectively. Prevalence a...
Source: Journal of Tropical Medicine - June 3, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Potential Use of Euphorbia hirta for Dengue: A Systematic Review of Scientific Evidence.
Authors: Perera SD, Jayawardena UA, Jayasinghe CD Abstract Euphorbia hirta commonly known as Tawa-Tawa is a plant used in folklore medicine in the Philippines for the treatment of dengue. Though, E. hirta has been extensively investigated for numerous bioactivities, limited studies have been conducted on the antidengue activity. Thus, the present study provides a comprehensive review of studies conducted on the antidengue activity of E. hirta. A systematic literature survey was carried out in scientific databases, PubMed®, Scopus, and Google Scholar, for research carried on the antidengue activity of E. hirta. ...
Source: Journal of Tropical Medicine - June 1, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Evaluating Malaria Prevalence Using Clinical Diagnosis Compared with Microscopy and Rapid Diagnostic Tests in a Tertiary Healthcare Facility in Rivers State, Nigeria.
Authors: Wogu MN, Nduka FO Abstract The World Health Organization's policy on laboratory test of all suspected malaria cases before treatment has not yielded significant effects in several rural areas of Sub-Saharan Africa due to inadequate diagnostic infrastructure, leading to high morbidity and mortality rates. A cross-sectional randomized study was conducted to evaluate the validity of clinical malaria diagnosis through comparison with microscopy and rapid diagnostic test kits (RDTs) using 1000 consenting outpatients of a tertiary hospital in Nigeria. Physicians conducted clinical diagnosis, and blood samples we...
Source: Journal of Tropical Medicine - June 1, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Risk Factors for Soil-Transmitted Helminthiasis in Preschool Children Living in Farmland, North Sumatera, Indonesia.
This study was intended to determine STH infection risk factors in preschool children. Methods: A cross-sectional study was conducted in Suka Village, North Sumatera, Indonesia, from October to December 2016. Subjects were children aged 1 to 5 years without history of taking antihelminthic. Subjects were obtained by consecutive sampling. Demographic data and risk factors for helminthiasis were collected using questionnaire-based interview. Subjects were divided into two groups, positive and negative STH infection, based on Kato Katz method. Analysis was done using chi-square and logistic regression test. p value
Source: Journal of Tropical Medicine - June 1, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Diversity of Dengue Virus Serotype in Endemic Region of South Sulawesi Province.
The objective of this research was to investigate serotype diversity pattern of dengue hemorrhagic fever virus by using real-time-polymerase chain reaction (RT-PCR) method. It was an explorative laboratory research in endemic dengue fever area in South Sulawesi Province, Indonesia, that is, Makassar municipality and Maros and Gowa region. Serological examination was carried out using real-time-polymerase chain reaction (RT-PCR) method to determine the serotype of dengue virus. The data showed that, of 30 patients, 20 patients (66.67%) were from Makassar municipality: 10 patients (33.33%) from Gowa region and 10 patients (3...
Source: Journal of Tropical Medicine - June 1, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Lateral Flow Loop-Mediated Isothermal Amplification Test with Stem Primers: Detection of Cryptosporidium Species in Kenyan Children Presenting with Diarrhea.
Conclusion. The developed stem LFD LAMP test is an appropriate method for the detection of C. hominis, C. parvum, and C. meleagridis DNA in human stool samples. It can be used in algorithm with other diagnostic tests and may offer promise as an effective diagnostic tool in the control of cryptosporidiosis. PMID: 29681951 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - April 25, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Determinants of Antenatal Healthcare Utilisation by Pregnant Women in Third Trimester in Peri-Urban Ghana.
Authors: Akowuah JA, Agyei-Baffour P, Awunyo-Vitor D Abstract Access to quality healthcare still remains a major challenge in the efforts at reversing maternal morbidity and mortality. Despite the availability of established maternal health interventions, the health of the expectant mother and the unborn child remains poor due to low utilisation of interventions. The study examined the socioeconomic determinants of antenatal care utilisation in peri-urban Ghana using pregnant women who are in their third trimester. Two-stage sampling technique was used to sample 200 pregnant women who were in their third trimester ...
Source: Journal of Tropical Medicine - April 19, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Determinants of Chronic Respiratory Symptoms among Pharmaceutical Factory Workers.
Conclusion: Previous history of respiratory diseases, family history of chronic respiratory diseases, previous dusty working environment, smoking, and service years were determinants of chronic respiratory symptoms. Public health endeavors to prevent the burden of chronic respiratory symptoms among pharmaceutical factory workers should target the reduction of adverse workplace exposures and discouragement of smoking. PMID: 29666655 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - April 19, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Hepatitis B Virus Infection in Tanzania: Current Status and Challenges.
Authors: Kilonzo SB, Gunda DW, Mpondo BCT, Bakshi FA, Jaka H Abstract Hepatitis B is one of the most common infectious diseases in the world with high prevalence in most of sub-Saharan Africa countries. The complexity in its diagnosis and treatment poses a significant management challenge in the resource-limited settings including Tanzania, where most of the tests and drugs are either unavailable or unaffordable. This mini review aims at demonstrating the current status of the disease in the country and discussing the concomitant challenges in diagnosis, treatment, and prevention. PMID: 29666656 [PubMed] (Sourc...
Source: Journal of Tropical Medicine - April 19, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

The Effects of Aloe vera Cream on the Expression of CD4+ and CD8+ Lymphocytes in Skin Wound Healing.
Authors: Prakoso YA, Kurniasih Abstract The aim of this study is to explore the effect of topical application of Aloe vera on skin wound healing. Thirty-six male Sprague-Dawley rats weighing 150-200 grams were divided into four groups. All groups were anesthetized, shaved, and exposed to round full-thickness punch biopsy on the back: group I (control); group II (treated with 1% Aloe vera cream); group III (treated with 2% Aloe vera cream); and group IV (treated with madecassol®). The treatments were given once a day. Macroscopic and microscopic examination were observed at 5, 10, and 15 days after skin biopsy. ...
Source: Journal of Tropical Medicine - April 19, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Phylogenetic Analysis of Dengue Virus in Bangkalan, Madura Island, East Java Province, Indonesia.
Authors: Sucipto TH, Kotaki T, Mulyatno KC, Churrotin S, Labiqah A, Soegijanto S, Kameoka M Abstract Dengue virus (DENV) infection is a major health issue in tropical and subtropical areas. Indonesia is one of the biggest dengue endemic countries in the world. In the present study, the phylogenetic analysis of DENV in Bangkalan, Madura Island, Indonesia, was performed in order to obtain a clearer understanding of its dynamics in this country. A total of 359 blood samples from dengue-suspected patients were collected between 2012 and 2014. Serotyping was conducted using a multiplex Reverse Transcriptase-Polymerase C...
Source: Journal of Tropical Medicine - April 19, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Health Related Quality of Life among TB Patients: Question Mark on Performance of TB DOTS in Pakistan.
Conclusion. The results of the present study concluded that TB patients had poor HRQoL in spite of the new therapeutic strategies and free availability of medicines. The disease had a negative impact on HRQoL of TB patients across all domains. PMID: 29623094 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - April 8, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Understanding Unlicensed Drug Vendor Practices Related to Childhood Malaria in One Rural District of Uganda: An Exploratory Study.
This study investigated unlicensed drug outlets' practices for the management of malaria in the rural district of Butaleja, Uganda. A qualitative design using semistructured interviews was used. Interviews were recorded, translated, transcribed, and analyzed using thematic analysis. A total of 75 vendors, representing 85% of the outlets in the study area, were interviewed. Most of the vendors were associated with a drug shop type of outfit. About three-quarters reported having completed some level of postsecondary education, but just one-tenth of the vendors had qualifications that made them eligible to apply for a license...
Source: Journal of Tropical Medicine - April 8, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Repellent Activity of TRIG (N-N Diethyl Benzamide) against Man-Biting Mosquitoes.
Authors: Msangi S, Kweka E, Mahande A Abstract A study was conducted to assess efficacy of a new repellent brand TRIG (15% N-N Diethyl Benzamide) when compared to DEET (20% N-N Methyl Toluamide). The repellents were tested in laboratory and field. In the laboratory, the repellence was tested on human volunteers, by exposing their repellent-treated arms on starved mosquitoes in cages for 3 minutes at hourly intervals, while counting the landing and probing attempts. Anopheles gambiae and Aedes aegypti mosquitoes were used. Field evaluation was conducted by Human Landing Catch technique. During the night, the repelle...
Source: Journal of Tropical Medicine - March 20, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Knowledge and Acceptability of Human Papillomavirus Vaccination among Women Attending the Gynaecological Outpatient Clinics of a University Teaching Hospital in Lagos, Nigeria.
This study was aimed at determining the knowledge and acceptability of HPV vaccine among women attending the gynaecology clinics of the Lagos University Teaching Hospital (LUTH). Methods: This was a descriptive cross-sectional study involving 148 consecutively selected women attending the gynaecology clinic of LUTH. Relevant information was obtained from these women using an interviewer-administered questionnaire. The data was analysed and then presented by simple descriptive statistics using tables and charts. Chi-square statistics were used to test the association between the sociodemographical variables and acceptan...
Source: Journal of Tropical Medicine - February 9, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Performance Evaluation of Commercial Dengue Diagnostic Tests for Early Detection of Dengue in Clinical Samples.
Authors: Mat Jusoh TNA, Shueb RH Abstract The shattering rise in dengue virus infections globally has created a need for an accurate and validated rapid diagnostic test for this virus. Rapid diagnostic test (RDT) and reverse transcription-polymerase chain reaction (RT-PCR) diagnostic detection are useful tools for diagnosis of early dengue infection. We prospectively evaluated the diagnostic performance of nonstructural 1 (NS1) RDT and real-time RT-PCR diagnostic kits in 86 patient serum samples. Thirty-six samples were positive for dengue NS1 antigen while the remaining 50 were negative when tested with enzyme-lin...
Source: Journal of Tropical Medicine - January 31, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

A Review on the Cosmeceutical and External Applications of Nigella sativa.
Authors: Eid AM, Elmarzugi NA, Abu Ayyash LM, Sawafta MN, Daana HI Abstract It is estimated by the World Health Organization (WHO) that most of the world's population depends on herbal medicine for their health care. Nigella sativa (N. sativa), also known as black-caraway and as "Kalonji," is a well-known seed all over the world. It is one of the most common medicinal plants worldwide and contains many useful chemical constituents that we can find in its fixed oil, such as thymoquinone, thymohydroquinone, dithymoquinone, thymol, nigellicine, carvacrol, nigellimine, nigellicine, nigellidine, and alpha-hede...
Source: Journal of Tropical Medicine - January 25, 2018 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Synthesis, SAR, and Docking Studies Disclose 2-Arylfuran-1,4-naphthoquinones as In Vitro Antiplasmodial Hits.
Authors: Borgati TF, do Nascimento MFA, Bernardino JF, Martins LCO, Taranto AG, de Oliveira AB Abstract A total of 28 lapachol-related naphthoquinones with four different scaffolds were synthesized and spectroscopically characterized. In vitro antiplasmodial activity was assayed against the chloroquine-resistant Plasmodium falciparum W2 strain by the parasite lactate dehydrogenase (pLDH) method. Cytotoxicity against Hep G2A16 cell was determined by the MTT assay. All compounds disclosed higher in vitro antiplasmodial activity than lapachol. Ortho- and para-naphthoquinones with a furan ring fused to the quinonoid mo...
Source: Journal of Tropical Medicine - December 13, 2017 Category: Tropical Medicine Tags: J Trop Med Source Type: research

Corrigendum to "Dengue Virus NS1 Protein as a Diagnostic Marker: Commercially Available ELISA and Comparison to qRT-PCR and Serological Diagnostic Assays Currently Used by the State of Florida".
Corrigendum to "Dengue Virus NS1 Protein as a Diagnostic Marker: Commercially Available ELISA and Comparison to qRT-PCR and Serological Diagnostic Assays Currently Used by the State of Florida". J Trop Med. 2017;2017:2046864 Authors: Ambrose JH, Sekaran SD, Azizan A Abstract [This corrects the article DOI: 10.1155/2017/8072491.]. PMID: 29209371 [PubMed - in process] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - December 8, 2017 Category: Tropical Medicine Tags: J Trop Med Source Type: research

The Burden and Trend of Blood-Borne Pathogens among Asymptomatic Adult Population in Akwatia: A Retrospective Study at the St. Dominic Hospital, Ghana.
Conclusion: Asymptomatic blood-borne pathogen burden was high among the adult population in Akwatia. Gender variations in HBV, HCV, and Syphilis infections in the cumulative four-year burden were observed. Awareness needs to be created, especially in the older generation. PMID: 29181037 [PubMed] (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - November 29, 2017 Category: Tropical Medicine Tags: J Trop Med Source Type: research