Deglycosylation of Excretory-Secretory Antigens of the Second-Stage Larvae of < em > Toxocara cati < /em > Improves Its Efficacy in the Diagnosis of Human Toxocariasis
CONCLUSION: Results of the current study indicate that the chemical removal of the glycan epitopes of T. cati ES antigens significantly reduces cross-reactivity rates with other parasitic infections. Considering the findings of the present study, the dTES antigens seem to be suitable antigens for the serodiagnosis of human toxocariasis.PMID:37492799 | PMC:PMC10365917 | DOI:10.1155/2023/3024063 (Source: Journal of Tropical Medicine)
Source: Journal of Tropical Medicine - July 26, 2023 Category: Tropical Medicine Authors: Ali Pouryousef Bahador Sarkari Amir Mootabi Alavi Mostafa Omidian Fattaneh Mikaeili Source Type: research
Status of the Multidrug Resistance-1 Gene of < em > Plasmodium falciparum < /em > in Four Malaria Epidemiological Strata, Two Decades after the Abolition of Chloroquine as First-Line Treatment for Uncomplicated Malaria in Cameroon
J Trop Med. 2023 Jul 1;2023:6688380. doi: 10.1155/2023/6688380. eCollection 2023.ABSTRACTDrug-resistant malaria parasites pose a threat to global malaria control efforts, and it is important to know the extent of these drug-resistant mutations in each region to determine appropriate control measures. Chloroquine (CQ) was widely used in Cameroon for decades, but its declining clinical efficacy due to resistance prompted health authorities in 2004 to resort to artemisinin-based combination therapy (ACT) as the first-line treatment for uncomplicated malaria. Despite numerous efforts to control malaria, it persists, and the em...
Source: Journal of Tropical Medicine - July 10, 2023 Category: Tropical Medicine Authors: David Denis Sofeu-Feugaing Fabrice Nkengeh Ajonglefac Marcel Nyuylam Moyeh Tobias Obejum Apinjoh Marianne Elodie Essende Gilchrist Destin Talla Kouam Stephen Mbigha Ghogomu Source Type: research
