Antibacterial and Antioxidant Efficacies of Secondary Metabolites from the Roots of < em > Cyphostemma adenocaule < /em > : A Combined < em > In Vitro < /em > and < em > In Silico < /em > Study
J Trop Med. 2024 Mar 6;2024:1679695. doi: 10.1155/2024/1679695. eCollection 2024.ABSTRACTCyphostemma adenocaule is a therapeutic plant traditionally used to treat rabies, snake bite, diarrhea, and wound healing. To address the bioactive compounds exhibiting these activities, we performed a comprehensive study on the roots of the plant. Thus, the present study aims to inspect the in vitro antioxidant and antibacterial efficacies of compounds isolated from the combined dichloromethane : methanol (1 : 1) and methanol extracts of C. adenocaule along with the in silico study of their interaction with selected protein targets. T...
Source: Journal of Tropical Medicine - March 14, 2024 Category: Tropical Medicine Authors: Hadush Gebrehiwot Yadessa Melaku Muhdin Aliye Urgessa Ensermu Aman Dekebo Milkyas Endale Daniel Rentsch Mo Hunsen Source Type: research
The Malaria Burden: A South African Perspective
J Trop Med. 2024 Feb 23;2024:6619010. doi: 10.1155/2024/6619010. eCollection 2024.ABSTRACTMalaria is a deadly disease caused by protozoan pathogens of the Plasmodium parasite. Transmission to humans occurs through the bite of an infected female Anopheles mosquito. According to the World Health Organization (WHO), an estimated 247 million cases of malaria were recorded worldwide in 2021, with approximately 619 000 malaria deaths. The initial signs of malaria can be mild and challenging to diagnose due to the signs and symptoms being similar to those of other illnesses. The malaria burden remains largely concentrated in the ...
Source: Journal of Tropical Medicine - March 4, 2024 Category: Tropical Medicine Authors: Marissa Balmith Charlise Basson Sarel J Brand Source Type: research
