In vitro antiviral activity of Cinnamomum cassia and its nanopartilces against H7N3 influenza A virus.
In this study, we synthesized silver nanoparticles using Cinnamomum cassia (Cinnamon) and evaluated their activity against highly pathogenic avian influenza virus subtype H7N3. The synthesized nanoparticles were characterized using UV-Vis absorption spectroscopy, scanning electron microscopy (SEM) and fourier transform infrared spectroscopy (FTIR). Cinnamon bark extract and its nanoparticles were tested against H7N3 Influenza A virus in Vero cells and the viability of cells were determined by tetrazolium dye (MTT) assay. The silver nanoparticles derived from Cinnamon extract enhanced the antiviral activity and were found t...
Source: Journal of Microbiology and Biotechnology - September 25, 2015 Category: Biotechnology Authors: Fatima M, Zaidi NS, Amraiz D, Afzal F Tags: J Microbiol Biotechnol Source Type: research
Quick and easy preparation method for decoctions of kampo formula (part 3): Extraction efficiency of the IPCD method for volatile compounds
ConclusionThe IPCD method is outstanding for the decoction of crude drugs containing volatile compounds. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - September 1, 2015 Category: Complementary Medicine Authors: Tsukasa Fueki, Megumi Sumino, Toshiaki Makino, Takanori Matsuoka, Masashi Beppu, Koichiro Tanaka, Takao Namiki Tags: SHORT COMMUNICATION Source Type: research
Cinnamomum cassia: an implication of serotonin reuptake inhibition in animal models of depression.
Abstract
The aim of the study was to explore the traditional use of Cinnamomum cassia against depression. The standardised methanolic extract of the bark of C. cassia was evaluated for antidepressant activity using various behavioural tests, i.e. tail suspension test (TST), forced swim test (FST) and locomotor activity test. The serotonergic and noradrenergic modulation was assessed using 5-hydroxytryptophan (5-HTP)-induced head twitches and yohimbine potentiation tests, respectively. The fluoxetine and phenelzine were used as positive controls in the study. The C. cassia extract significantly decreased th...
Source: Natural Product Research - July 2, 2015 Category: Biochemistry Authors: Zada W, Zeeshan S, Bhatti HA, Mahmood W, Rauf K, Abbas G Tags: Nat Prod Res Source Type: research
Cinnamon and its Components Suppress Vascular Smooth Muscle Cell Proliferation by Up-Regulating Cyclin-Dependent Kinase Inhibitors.
Abstract
Cinnamomum cassia bark has been used in traditional herbal medicine to treat a variety of cardiovascular diseases. However, the antiproliferative effect of cinnamon extract on vascular smooth muscle cells (VSMCs) and the corresponding restenosis has not been explored. Hence, after examining the effect of cinnamon extract on VSMC proliferation, we investigated the possible involvement of signal transduction pathways associated with early signal and cell cycle analysis, including regulatory proteins. Besides, to identify the active components, we investigated the components of cinnamon extract on VS...
Source: The American Journal of Chinese Medicine - June 28, 2015 Category: Complementary Medicine Authors: Kwon H, Lee JJ, Lee JH, Cho WK, Gu MJ, Lee KJ, Ma JY Tags: Am J Chin Med Source Type: research
The traditional herbal medicine, Ge-Gen-Tang, inhibits pacemaker potentials by nitric oxide/cGMP dependent ATP-sensitive K+ channels in cultured interstitial cells of Cajal from mouse small intestine
Conclusion These results suggest that GGT inhibits pacemaker potentials in ICCs in a G protein-, cGMP- and NO-dependent manner through stimulation of α2 and β1-adrenoceptors. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - June 12, 2015 Category: Drugs & Pharmacology Source Type: research
Evaluation and predictive modeling the effects of spice extracts on raw chicken meat stored at different temperatures
Publication date: December 2015 Source:Journal of Food Engineering, Volume 166 Author(s): K. Radha krishnan , S. Babuskin , P. Azhagu Saravana Babu , M. Sivarajan , M. Sukumar In the present study, the anti-microbial and anti-oxidant effects of Syzygium aromaticum (SA), Cinnamomum cassia (CC) and Origanum vulgare (OV) on the shelf life of raw chicken meat stored at different temperatures (4, 10, 15 and 20°C±1) were studied. Gompertz model was used to model the microbial growth using the data from microbial analysis of meat samples. Arrhenius equation was applied to understand the effect of storage temperature on...
Source: Journal of Food Engineering - May 25, 2015 Category: Food Science Source Type: research
Development of kinetic model for testing antifungal effect of Thymus vulgaris L. and Cinnamomum cassia L. essential oils on Aspergillus flavus spores and application for optimization of synergistic effect
Publication date: 15 July 2015 Source:Biochemical Engineering Journal, Volume 99 Author(s): M. Pekmezovic , K. Rajkovic , A. Barac , L. Senerović , V. Arsic Arsenijevic The antifungal effect of essential oils (EOs) of Thymus vulgaris L. (EO T. vulgaris ) and Cinnamomum cassia L. (EO C. cassia ) against Aspergillus flavus spores was evaluated by determining minimum inhibitory concentration, minimum fungicidal concentrations and fungicidal kinetics. Kinetic model of fungicidal activity of individual EO T. vulgaris and EO C. cassia was developed and its parameters were used to make EO mixture with optimal ratio of...
Source: Biochemical Engineering Journal - April 10, 2015 Category: Biochemistry Source Type: research
Anti-diabetic nephropathy compounds from Cinnamomum cassia
Conclusions The results revealed that sesquiterpenoids may be the active compounds in C. cassia bark on diabetic nephropathy which provided new evidences for the traditional use of this herb to treat diabetic nephropathy and associated kidney diseases. (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - March 20, 2015 Category: Drugs & Pharmacology Source Type: research
Anti-inflammatory Effect of Cinnamaldehyde in Helicobacter pylori Induced Gastric Inflammation.
This study provides evidence that the anti-inflammatory effect of C. cassia on H. pylori-infected gastric cells is due to blockage of the NF-κB pathway by cinnamaldehyde. This agent can be considered as a potential candidate for in vivo and clinical studies against various H. pylori related gastric pathogenic processes.
PMID: 25744466 [PubMed - in process] (Source: Biological and Pharmaceutical Bulletin)
Source: Biological and Pharmaceutical Bulletin - March 8, 2015 Category: Drugs & Pharmacology Authors: Muhammad JS, Zaidi SF, Shaharyar S, Refaat A, Usmanghani K, Saiki I, Sugiyama T Tags: Biol Pharm Bull Source Type: research
Oryeongsan suppressed high glucose-induced mesangial fibrosis
Conclusion:
These results demonstrate that Oryeongsan has protective effect against renal proliferation, fibrosis, and inflammation. Therefore Oryeongsan may be specific therapies targeting renal dysfunction leading to diabetic nephropathy. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - February 22, 2015 Category: Complementary Medicine Authors: Jung YoonYun LeeSo LeeDae KangHo Lee Source Type: research
Synergistic Effect of Fragrant Herbs in Japanese Scent Sachets
Planta MedDOI: 10.1055/s-0034-1396138The sedative activity of eight aromatic natural medicines that are traditionally used in Japanese scent sachets was examined using an open field test with mice. Galangal (Kaempferia galanga), patchouli (Pogostemon cablin), sandalwood (Santalum album), spikenard (Nardostachys chinensis), cinnamon (Cinnamomum cassia), clove (Syzygium aromaticum), star anise (Illicium verum), and borneol (Dryobalanops aromatica) distilled oils were used. These natural medicines have various pharmacological effects. For example, galangal has insecticidal activity and clove extracts possess strong total anti...
Source: Planta Medica - February 11, 2015 Category: Drugs & Pharmacology Authors: Fujiwara, YumiIto, Michiho Tags: Original Papers Source Type: research
Cinnamic aldehyde treatment alleviates chronic unexpected stress-induced depressive-like behaviors via targeting cyclooxygenase-2 in mid-aged rats
Conclusion Cinnamic aldehyde exerted antidepressant-like effects in stressed mid-aged rats, and its mechanism of action appears to decrease COX-2 protein and activity. The current findings suggest that targeting COX-2 system might be benefit to the depression, especially elderly individuals and cinnamic aldehyde might be a promising medicine to treat the subjects in the depression. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - January 17, 2015 Category: Drugs & Pharmacology Source Type: research
Water extract of Cinnamomum cassia suppresses angiogenesis through inhibition of VEGF receptor 2 phosphorylation.
In this study, we found that a water extract of Cinnamomum cassia (CCWE) was a potent inhibitor of angiogenesis. In cultured human umbilical vein endothelial cells, CCWE suppressed vascular endothelial growth factor (VEGF)-induced proliferation, migration, invasion, tube formation, and intracellular signaling events such as phosphorylation of ERK, p38 and VEGFR2, and activation of matrix metalloproteinase. Furthermore, CCWE inhibited VEGF-induced vessel sprouting of rat aorta ex vivo. These findings might be of particular interest for drug development because VEGF signaling is a potential target for treatment of angiogenes...
Source: Bioscience, Biotechnology, and Biochemistry - January 3, 2015 Category: Biochemistry Authors: Kim E, Kim HJ, Kim T Tags: Biosci Biotechnol Biochem Source Type: research
An investigation of the bactericidal activity of selected essential oils to Aeromonas spp.
This study was done to determine whether selected plant-derived essential oils were bactericidal to Aeromonas spp. Initially, twelve essential oils were evaluated using a disk diffusion assay to an isolate of A. salmonicida subsp. salmonicida, cause of fish furunculosis. The greatest zones of inhibition were obtained with oils of cinnamon Cinnamomum cassia, oregano Origanum vulgare, lemongrass Cymbopogon citratus and thyme Thymus vulgaris. Minimum bactericidal concentrations (MBC’s) were determined for these four oils, Allimed® (garlic extract, Allium sativum) and colloidal silver to sixty-nine isolates representing nin...
Source: Journal of Advanced Research - January 3, 2015 Category: Research Source Type: research
Herbal medicine for the management of polycystic ovary syndrome (PCOS) and associated oligo/amenorrhoea and hyperandrogenism; a review of the laboratory evidence for effects with corroborative clinical findings
Conclusions:
Preclinical and clinical studies provide evidence that six herbal medicines may have beneficial effects for women with oligo/amenorrhea, hyperandrogenism and PCOS. However the quantity of pre-clinical data was limited, and the quality of clinical evidence was variable. Further pre-clinical studies are needed to explain the effects of herbal medicines not included in this review with current clinical evidence but an absence of pre-clinical data. (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - December 18, 2014 Category: Complementary Medicine Authors: Susan ArentzJason AbbottCaroline SmithAlan Bensoussan Source Type: research
