Three new furanones from endophytic fungus < em > Hypoxylon vinosopulvinatum < /em > DYR-1-7 from < em > Cinnamomum cassia < /em > with their antifungal activity
Nat Prod Res. 2023 Jun 2:1-8. doi: 10.1080/14786419.2023.2218530. Online ahead of print.ABSTRACTHypoxylon vinosopulvinatum DYR-1-7 is a endophytic fungus isolated from the Cinnamomum cassia Presl and has an inhibitory effect on Lasiodiplodia pseudotheobromae. Three new furanones, hypoxylonone A-C (1-3), as well as three known compounds (4-6), were isolated from an EtOAc extract of H. vinosopulvinatum DYR-1-7. The structures were determined by spectroscopic data analysis using UV, IR, 1D-, 2D-NMR and HR-ESI-MS. The absolute configurations of 1-3 were elucidated by electronic circular dichroism (ECD) analyses. In the antifun...
Source: Natural Product Research - June 2, 2023 Category: Biochemistry Authors: Jia Lv Hong Zhou Limei Dong Hao Wang Li Yang Haiqian Yu Peixi Wu Le Zhou Quan Yang Yongqian Liang Bi Luo Source Type: research

< em > Cinnamomum cassia < /em > on Arterial Stiffness and Endothelial Dysfunction in Type 2 Diabetes Mellitus: Outcomes of a Randomized, Double-Blind, Placebo-Controlled Clinical Trial
This study aimed to evaluate the effect of C. cassia on arterial stiffness and endothelial dysfunction (ED) in patients with type 2 diabetes mellitus (T2DM). A randomized, double-blind, placebo-controlled clinical trial was carried out in 18 subjects aged 40-65 years, with a diagnosis of T2DM of one year or less since diagnosis and treated with Metformin 850 mg daily. Patients were randomly assigned to receive either C. cassia or a placebo in 1000 mg capsules, thrice a day, before each meal for 12 weeks. At baseline and after 12 weeks of intervention, brachial-ankle pulse wave velocity and Flow Mediated Dilation were measu...
Source: Molecular Medicine - June 1, 2023 Category: Molecular Biology Authors: Jes ús S Delgadillo-Centeno Fernando Grover-P áez Sandra O Hern ández-González Mar ía G Ramos-Zavala David Cardona-M üller Alicia L ópez-Castro Sara Pascoe-Gonz ález Source Type: research

Cinnamomum cassia on Arterial Stiffness and Endothelial Dysfunction in Type 2 Diabetes Mellitus: Outcomes of a Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Journal of Medicinal Food, Ahead of Print. (Source: Journal of Medicinal Food)
Source: Journal of Medicinal Food - June 1, 2023 Category: Nutrition Authors: Jes ús S. Delgadillo-Centeno Fernando Grover-P áez Sandra O. Hern ández-González Mar ía G. Ramos-Zavala David Cardona-M üller Alicia L ópez-Castro Sara Pascoe-Gonz ález Source Type: research

Fumigant toxicity and behavioral alterations of six plant essential oils against the red fire ant (Solenopsis invicta Buren)
In this study, the HS-SPME-GC/MS method was used to determine the volatile components of six essential oils, namely Illicium verum Burm, Blumea balsamifera (L.) DC., Citrus limon Burm, Acorus tatarinowii Schott, Mosla chinensis Maxim, and Cinnamomum cassia Presl, as well as their fumigation activity against RIFA. D-Limonene was identified as a core volatile in all six essential oils. The effects of volatile substances from essential oils on the fumigation activity and behavior of RIFA workers were studied by closed fumigation method. Except for C. limon essential oil, all other five plant essential oils exhibit excellent f...
Source: Environmental Science and Pollution Research International - May 1, 2023 Category: Environmental Health Authors: Jiantao Fu Zewen Ma Lanying Wang Yunfei Zhang Yanping Luo Source Type: research

Molecules, Vol. 28, Pages 3685: Chemical Profile Determination and Quantitative Analysis of Components in Oryeong-san Using UHPLC-Q-Orbitrap-MS and UPLC-TQ-MS/MS
In this study, a method to both qualitatively and quantitively analyze the components of Oryeong-san (ORS), which is composed of five herbal medicines (Alisma orientale Juzepzuk, Polyporus umbellatus Fries, Atractylodes japonica Koidzumi, Poria cocos Wolf, and Cinnamomum cassia Presl) and is prescribed in traditional Oriental medicine practices, was established for the first time. First, ORS components were profiled using ultra-high-performance liquid chromatography/quadrupole Orbitrap mass spectrometry, and 19 compounds were clearly identified via comparison against reference standard compounds. Subsequently, a quantitati...
Source: Molecules - April 24, 2023 Category: Chemistry Authors: Seol Jang Ami Lee Youn-Hwan Hwang Tags: Article Source Type: research

Impact of dietary supplementation with Cinnamomum cassia essential oil on silver catfish (Rhamdia quelen): Toxicological effects and muscle antioxidant and fatty acid profiles
(Source: Journal of Toxicology and Environmental Health Part A)
Source: Journal of Toxicology and Environmental Health Part A - April 10, 2023 Category: Environmental Health Authors: Rossato Viana Rapachi Fortes Rodrigues Ribeiro Maria Heinzmann Alves da Cunha Cristina Zeppenfeld da Silva Fernandes Wagner Baldisserotto Figueiredo Gon çalves de Moraes Chitolina Justen Dellam éa Baldissera Source Type: research

Two new meroterpenoids from the bark of Cinnamomum cassia and their antioxidant activity
. (Source: Journal of Asian Natural Products Research)
Source: Journal of Asian Natural Products Research - April 3, 2023 Category: Complementary Medicine Authors: Cai-Hong Xie Shang-Xiong Huang Jin-Feng Li Zhi-Hui Luo Geng-Feng Huang Bing-Bing Yan Hong-Xia Fan Jun-Xia Zheng Zheng-Qun Zhou Hao Gao Source Type: research

Antifungal activity and aroma persistence of free and encapsulated Cinnamomum cassia essential oil in maize
The objective of this study was to evaluate the chemical composition and antifungal activity of free and encapsulated Cinnamomum cassia essential oil (EO) against Penicillium crustosum, Alternaria alternata, and Aspergillus flavus, and the aroma persistence in maize flour. Trans-cinnamaldehyde (TC) was identified as the major compound (86 %) in the C. cassia EO. The EO was encapsulated by spray-dryer with 45.26 % efficiency using gum arabic (GA) and maltodextrin (MD) in a ratio of 1:1 (m/m). C. cassia EO showed antifungal activity against A. alternata, A. flavus, and P. crustosum, with a minimum inhibitory concentration (M...
Source: International Journal of Food Microbiology - March 22, 2023 Category: Food Science Authors: Mariane Minozzo Marina Andreia de Souza Julia Lisboa Bernardi Bruna Maria Saorin Puton Eunice Valduga Clarice Steffens Natalia Paroul Rog ério Luis Cansian Source Type: research

Antifungal activity and aroma persistence of free and encapsulated Cinnamomum cassia essential oil in maize
The objective of this study was to evaluate the chemical composition and antifungal activity of free and encapsulated Cinnamomum cassia essential oil (EO) against Penicillium crustosum, Alternaria alternata, and Aspergillus flavus, and the aroma persistence in maize flour. Trans-cinnamaldehyde (TC) was identified as the major compound (86 %) in the C. cassia EO. The EO was encapsulated by spray-dryer with 45.26 % efficiency using gum arabic (GA) and maltodextrin (MD) in a ratio of 1:1 (m/m). C. cassia EO showed antifungal activity against A. alternata, A. flavus, and P. crustosum, with a minimum inhibitory concentration (M...
Source: International Journal of Food Microbiology - March 22, 2023 Category: Food Science Authors: Mariane Minozzo Marina Andreia de Souza Julia Lisboa Bernardi Bruna Maria Saorin Puton Eunice Valduga Clarice Steffens Natalia Paroul Rog ério Luis Cansian Source Type: research

An Analysis of the Toxicity, Antioxidant, and Anti-Cancer Activity of Cinnamon Silver Nanoparticles in Comparison with Extracts and Fractions of Cinnamomum Cassia at Normal and Cancer Cell Levels
Nanomaterials (Basel). 2023 Mar 5;13(5):945. doi: 10.3390/nano13050945.ABSTRACTIn this work, the extract of cinnamon bark was used for the green synthesis of cinnamon-Ag nanoparticles (CNPs) and other cinnamon samples, including ethanolic (EE) and aqueous (CE) extracts, chloroform (CF), ethyl acetate (EF), and methanol (MF) fractions. The polyphenol (PC) and flavonoid (FC) contents in all the cinnamon samples were determined. The synthesized CNPs were tested for the antioxidant activity (as DPPH radical scavenging percentage) in Bj-1 normal cells and HepG-2 cancer cells. Several antioxidant enzymes, including biomarkers, s...
Source: Cancer Control - March 11, 2023 Category: Cancer & Oncology Authors: Y G El-Baz A Moustafa M A Ali G E El-Desoky S M Wabaidur M M Faisal Source Type: research

An Analysis of the Toxicity, Antioxidant, and Anti-Cancer Activity of Cinnamon Silver Nanoparticles in Comparison with Extracts and Fractions of Cinnamomum Cassia at Normal and Cancer Cell Levels
Nanomaterials (Basel). 2023 Mar 5;13(5):945. doi: 10.3390/nano13050945.ABSTRACTIn this work, the extract of cinnamon bark was used for the green synthesis of cinnamon-Ag nanoparticles (CNPs) and other cinnamon samples, including ethanolic (EE) and aqueous (CE) extracts, chloroform (CF), ethyl acetate (EF), and methanol (MF) fractions. The polyphenol (PC) and flavonoid (FC) contents in all the cinnamon samples were determined. The synthesized CNPs were tested for the antioxidant activity (as DPPH radical scavenging percentage) in Bj-1 normal cells and HepG-2 cancer cells. Several antioxidant enzymes, including biomarkers, s...
Source: Cancer Control - March 11, 2023 Category: Cancer & Oncology Authors: Y G El-Baz A Moustafa M A Ali G E El-Desoky S M Wabaidur M M Faisal Source Type: research

[ASAP] Bioactive Piperazic Acid-Bearing Cyclodepsipeptides, Lydiamycins E –H, from an Endophytic < italic toggle="yes" > Streptomyces < /italic > sp. Associated with < italic toggle="yes" > Cinnamomum cassia < /italic >
Journal of Natural ProductsDOI: 10.1021/acs.jnatprod.2c00902 (Source: Journal of Natural Products)
Source: Journal of Natural Products - February 22, 2023 Category: Biochemistry Authors: Weihong Wang, Seungjin Kim, Thi Hanh Nguyen Vu, Ngoc Tung Quach, Eunseok Oh, Kyu-Hyung Park, Chanyoon Park, Youbin Cho, Hyeseon Jang, Eun Roh, JunI Lee, Eunmo Kang, SongJoo Han, Quyet-Tien Phi, and Heonjoong Kang Source Type: research

Molecules, Vol. 28, Pages 2015: Identification of Differential Compositions of Aqueous Extracts of Cinnamomi Ramulus and Cinnamomi Cortex
Zhi-Min Wang Cinnamomi ramulus (CR) and Cinnamomi cortex (CC), both sourced from Cinnamomum cassia Presl, are commonly used Chinese medicines in the Chinese Pharmacopeia. However, while CR functions to dissipate cold and to resolve external problems of the body, CC functions to warm the internal organs. To clarify the material basis of these different functions and clinical effects, a simple and reliable UPLC-Orbitrap-Exploris-120-MS/MS method combined with multivariate statistical analyses was established in this study with the aim of exploring the difference in chemical compositions of aqueous extracts of CR and C...
Source: Molecules - February 21, 2023 Category: Chemistry Authors: Pei Wang Jun Chi Hui Guo Shun-Xiang Wang Jing Wang Er-Ping Xu Li-Ping Dai Zhi-Min Wang Tags: Article Source Type: research

A Compound Essential Oil Alters Stratum Corneum Structure, Potentially Promoting the Transdermal Permeation of Hydrophobic and Hydrophilic Ingredients
CONCLUSION: It is concluded that the prepared CEO can promote the transdermal permeation of hydrophobic and hydrophilic ingredients. This study will provide a reference for the application of the prepared CEO in the development of cosmeceuticals with natural efficacy.PMID:36683374 | DOI:10.2174/1567201820666230120122206 (Source: Current Drug Delivery)
Source: Current Drug Delivery - January 23, 2023 Category: Drugs & Pharmacology Authors: Na Yang Xinyi Ai Kang Cheng Yihan Wu Zhi Lu Zhenda Liu Teng Guo Nianping Feng Source Type: research