Influence of herbal combinations on the extraction efficiencies of chemical compounds from Cinnamomum cassia, Paeonia lactiflora, and Glycyrrhiza uralensis, the herbal components of Gyeji-tang, evaluated by HPLC method
In conclusion, chemical interactions between compositional herbal medicines may occur when herbs are co-decocted. This study provides insight of understanding the herbal interactions in herbal formulae. Graphical abstract (Source: Journal of Pharmaceutical and Biomedical Analysis)
Source: Journal of Pharmaceutical and Biomedical Analysis - July 9, 2016 Category: Drugs & Pharmacology Source Type: research
Traditional Chinese medicine Guizhi Fuling capsule used for therapy of dysmenorrhea via attenuating uterus contraction
Conclusions Both in vivo and in vitro results indicated that GZFLC possessed a significant spasmolytic effect on uterine tetanic contraction. The present study provides in vivo and in vitro experimental evidence to support the use of GZFLC for the clinical treatment of primary dysmenorrheal (PD). Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - July 1, 2016 Category: Drugs & Pharmacology Source Type: research
Essential Oils, Part III: Chemical Composition.
Abstract
Data on the chemistry of essential oils which have caused contact allergy are provided. The largest group of chemicals found in essential oils consists of terpenes. The number of identified components usually ranges from 100 to 250, but in some oils (lavender, geranium, rosemary) 450 to 500 chemicals have been found. Many chemicals are present in a large number of oils, up to 98% for β-caryophyllene and 97% for limonene. Chemicals that are important constituents of >20 oils are limonene, linalool, and α-pinene. In many essential oils, there are 2 to 5 components which together constitute over...
Source: Dermatitis - June 30, 2016 Category: Dermatology Authors: de Groot AC, Schmidt E Tags: Dermatitis Source Type: research
Trimer procyanidin oligomers contribute to the protective effects of cinnamon extracts on pancreatic β-cells in vitro.
CONCLUSION: Trimer procyanidins in the cinnamon extracts contribute to the pancreatic β-cell protection, thus to the anti-diabetic activity.
PMID: 27238208 [PubMed - as supplied by publisher] (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - May 29, 2016 Category: Drugs & Pharmacology Authors: Sun P, Wang T, Chen L, Yu BW, Jia Q, Chen KX, Fan HM, Li YM, Wang HY Tags: Acta Pharmacol Sin Source Type: research
538 The synergistic effect of cinnamon cassia oil and erythromycin on overcoming antibiotic resistant Staphylococcus aureus
Increasing antibiotic resistance in Staphylococcus aureus has prompted the need for alternative treatments. One potential strategy involves synergism between antibiotics and essential plant oils. The antimicrobial activity of essential oils has long been recognized, but used only recently synergistically with antibiotics. The goal of this study was to assess the inhibitory effect of varying combinations of cinnamon oil and erythromycin on the growth of erythromycin-resistant S. aureus. Using the disk diffusion method, antibiotic susceptibility profiles were established for S. (Source: Journal of Investigative Dermatology)
Source: Journal of Investigative Dermatology - April 20, 2016 Category: Dermatology Authors: G.R. Delost, C. Haydanek, N. Carty, C. Keller Tags: Pharmacology & Drug Development Source Type: research
Fumigant and contact toxicity of 22 wooden essential oils and their major components against Drosophila suzukii (Diptera: Drosophilidae)
Publication date: Available online 19 March 2016 Source:Pesticide Biochemistry and Physiology Author(s): Junheon Kim, Miyeon Jang, Eunsik Shin, Jeongmin Kim, Si Hyeock Lee, Chung Gyoo Park Fumigant and contact toxicities of 22 plant essential oils (EOs) from 14 families and their constituents against the adult spotted wing drosophila (SWD), Drosophila suzukii were examined. Analyses by GC, GC-MS, and NMR led to the identification of 2, 16, 13, 4, 6, 9, and 10 compounds from Gaultheria fragrantissima, Croton anistatum, Illicium verum, Liquidamabar orientalis, Cinnamomum cassia, Rosa damasena, and Santalum al...
Source: Pesticide Biochemistry and Physiology - April 17, 2016 Category: Biochemistry Source Type: research
Ba-Wei-Die-Huang-Wan (Hachimi-jio-gan) can ameliorate cyclophosphamide-induced ongoing bladder overactivity and acidic adenosine triphosphate solution-induced hyperactivity on rats prestimulated bladder
Conclusion BWDHW treatment can ameliorate CYP-induced ongoing bladder overactivity and suppress mucosal P2X2, P2X3, M2, and M3 receptor protein overexpression, as well as detrusor M2 and M3 receptor protein overexpression. BWDHW pretreatment can reduce acidic ATP solution-provoked hyperactivity by preventing TRPV1 receptor overexpression in CYP-treated bladder mucosa and inhibiting P2X3 receptor overexpression in naïve bladder mucosa. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - March 8, 2016 Category: Drugs & Pharmacology Source Type: research
Bactericidal effects of Cinnamon cassia oil against bovine mastitis bacterial pathogens
This study examined the antimicrobial activity of Cinnamon cassia oil against major pathogens causing bacterial bovine mastitis, its miscibility in milk and possible antimicrobial mechanisms. C. cassia oil had inhibitory activity against all tested pathogen isolates from bovine mastitis. We conducted disk diffusion assay and found that discs with 20 μL of 2% (v/v) C. cassia oil solution resulted in inhibition zones of 29.6, 19.1, 27.0, 33.3 and 30.7 mm for Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus hyicus, Staphylococcus xylosus and Escherichia coli 29, respectively. The minimum inhibitory conce...
Source: Food Control - February 28, 2016 Category: Food Science Source Type: research
Differentiating Parts of Cinnamomum Cassia using LC-qTOF-MS in Conjunction with Principal Component Analysis.
In this study, chemical fingerprints of cinnamon bark, cinnamon twigs, and shaved cinnamon bark were established using liquid chromatography quadruple time-of-flight mass spectrometry (LC-qTOF-MS) in conjunction with principal component analysis (PCA). From 125 samples of cinnamon, we identified the following eight compounds and their the detection ratios: coumarin, cinnamaldehyde, cinnamyl alcohol, cinnamic acid, 2-hydroxycinnamaldehyde, 2-hydroxycinnamic acid, 2-methoxycinnamaldehyde, and 4-methoxycinnamaldehyde. Of these, 4-methoxycinnamaldehyde presented the largest variations in detection ratio, making up 64.0%, 97.4%...
Source: Biomedical Chromatography : BMC - February 12, 2016 Category: Biomedical Science Authors: Chen PY, Yu JW, Lu FL, Lin MC, Cheng HF Tags: Biomed Chromatogr Source Type: research
Agrimonia pilosa Ledeb., Cinnamomum cassia Blume, and Lonicera japonica Thunb. protect against cognitive dysfunction and energy and glucose dysregulation by reducing neuroinflammation and hippocampal insulin resistance in β-amyloid-infused rats
10.1080/1028415X.2015.1135572 < br/ > Sunmin Park (Source: Nutritional Neuroscience)
Source: Nutritional Neuroscience - February 4, 2016 Category: Nutrition Authors: Sunmin Park Suna Kang Da Sol Kim Bo Rerum Moon Source Type: research
Evaluation of the effects of active fractions of chinese medicine formulas on IL-1β, IL-6, and TNF-α release from ANA-1 murine macrophages
Conclusions Sgu and Ves are the primary active fractions of YTN involved in stimulating immune responses. The YTN prescription was reasonably effective at promoting cellular immune responses. Chinese rice wine, the YTN vehicle, strengthened the immunoregulatory activity of YTN. The results of this study demonstrate that the YTN recipe could be improved by reducing the number of CMMs and altering some active fractions without reducing its activity to promote cellular immune responses. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - January 29, 2016 Category: Drugs & Pharmacology Source Type: research
UHPLC/Q-TOFMS-based metabolomics for the characterization of cold and hot properties of Chinese materia medica
Conclusions There is a strong connection between the cold/hot property of CMMs and lysophosphatidylcholines metabolism. This study offers new insight into CMM properties and their clinical application. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - January 12, 2016 Category: Drugs & Pharmacology Source Type: research
Cinnamaldehyde affects the biological behavior of human colorectal cancer cells and induces apoptosis via inhibition of the PI3K/Akt signaling pathway.
In conclusion, CA has the potential to be developed as a new antitumor drug. The mechanisms of action involve the regulation of expression of genes involved in apoptosis, invasion and adhesion via inhibition of the PI3K/Akt signaling pathway.
PMID: 26677144 [PubMed - as supplied by publisher] (Source: Oncology Reports)
Source: Oncology Reports - December 20, 2015 Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
The glycaemic outcomes of Cinnamon, a review of the experimental evidence and clinical trials
Conclusion:
Cinnamon has the potential to be a useful add-on therapy in the discipline of integrative medicine in managing type 2 diabetes. At present the evidence is inconclusive and long-term trials aiming to establish the efficacy and safety of cinnamon is needed. However, high coumarin content of Cinnamomum cassia is a concern, but Cinnamomum zeylanicum with its low coumarin content would be a safer alternate. (Source: Nutrition Journal)
Source: Nutrition Journal - October 16, 2015 Category: Nutrition Authors: Arjuna Medagama Source Type: research
Antimicrobial effect against different bacterial strains and bacterial adaptation to essential oils used as feed additives.
Abstract
The aim of this study was to evaluate the antimicrobial activity and determine the minimum bactericidal concentration (MBC) of the essential oils derived from Origanum vulgare (oregano), Melaleuca alternifolia (tea tree), Cinnamomum cassia (cassia), and Thymus vulgaris (white thyme) against Salmonella Typhimurium, Salmonella Enteritidis, Escherichia coli, Staphylococcus aureus and Enterococcus faecalis. The study also investigated the ability of these different bacterial strains to develop adaptation after repetitive exposure to sub-lethal concentrations of these essential oils. The MBC of the ess...
Source: Canadian Journal of Veterinary Research - October 1, 2015 Category: Veterinary Research Authors: Melo AD, Amaral AF, Schaefer G, Luciano FB, de Andrade C, Costa LB, Rostagno MH Tags: Can J Vet Res Source Type: research
