Issue Information
Traditional& Kampo Medicine, Volume 7, Issue 1, Page 1-2, April 2020. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - April 1, 2020 Category: Complementary Medicine Tags: ISSUE INFORMATION Source Type: research

Acknowledgment
Traditional& Kampo Medicine, Volume 7, Issue 1, Page 53-53, April 2020. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - April 1, 2020 Category: Complementary Medicine Tags: ACKNOWLEDGMENT Source Type: research

The association in Kampo medicine between Oketsu (blood stasis) and sublingual vein width of the tongue on a tongue image analyzing system
ConclusionThe present study showed, for the first time, that patients with blood stasis tend to have a larger sublingual vein width based on an objective method. Moreover, TIAS, which can quantify tongue ‐related information objectively, may be considered useful for training and as a diagnostic aid. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - March 31, 2020 Category: Complementary Medicine Authors: Akira Morita, Aya Murakami, Yuki Watanabe, Yutaka Tamura, Akiko Suganami, Yuki Shiko, Yohei Kawasaki, Toshiya Nakaguchi, Sadayuki Ochi, Kazuho Okudaira, Yoshiro Hirasaki, Takao Namiki Tags: SHORT COMMUNICATION Source Type: research

Effects of Kampo therapy on prognosis in patients with idiopathic interstitial pneumonia (report 1)
ConclusionThis result is better than the expected period of survival (median survival) in previously published studies. This result suggests the efficacy of Kampo therapy for IIPs, especially IPF and f ‐NSIP. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - March 19, 2020 Category: Complementary Medicine Authors: Yukihiko Homma, Yoshinori Ohtsuka Tags: ORIGINAL ARTICLE Source Type: research

Cinnamomi Cortex and Scutellariae Radix in the Japanese herbal medicine Kampo saireito inhibit expression of iNOS through different mechanisms in hepatocytes
ConclusionCinnamomi Cortex and Scutellariae Radix can prevent the induction of iNOS gene expression, in part through NF ‐κB activation and IL‐1RI upregulation with different mechanisms, indicating that saireito containing both crude drugs may be a potential therapeutic treatment for injured livers. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - February 25, 2020 Category: Complementary Medicine Authors: Hideyuki Matsushima, Hidehiko Hishikawa, Hirokazu Miki, Masahiko Hatta, Richi Nakatake, Tadayoshi Okumura, Mikio Nishizawa, Masaki Kaibori, Mitsugu Sekimoto Tags: ORIGINAL ARTICLE Source Type: research

Effect of add ‐on administration of kamikihito with donepezil monotherapy in a patient with Alzheimer's disease
ConclusionCombination therapy with donepezil and kamikihito seems to be beneficial and worth considering for patients who are secondarily non ‐responsive to donepezil monotherapy. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - February 4, 2020 Category: Complementary Medicine Authors: Kazuyuki Ishida Tags: CASE REPORT Source Type: research

Effect of intraoral antioxidative capacity in orengedokuto
ConclusionThis almost noninvasive test method can easily evaluate the intraoral antioxidative capacity and was effective in verifying the antioxidative capacity of Kampo medicines. In OGT, Scutellaria Root made a significant contribution in the antioxidative capacity of the crude drug extract itselfin vitro and the intraoral antioxidative capacityin vivo. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - January 24, 2020 Category: Complementary Medicine Authors: Hiroaki Nishijima, Satoshi Takamatsu, Kazue Satoh, Remi Murase, Iori Taki, Daisuke Kamei, Kazuyoshi Kawazoe, Yukio Nemoto, Shinichi Iwai Tags: ORIGINAL ARTICLE Source Type: research

Usefulness of shosaikoto for pneumonia in combination with antibiotics
ABSTRACTAimThe value of Kampo medicine for the treatment of pneumonia is unclear. The aim of our study is to investigate the usefulness of shosaikoto for pneumonia in combination with antibiotics.MethodsWe retrospectively compared 39 cases treated only with Western medicine, including antibiotics (conventional group), with 22 cases treated with Western medicine, including antibiotics, and shosaikoto (combination group). We evaluated the duration of antibiotic treatment after admission, the febrile period, and the duration of oxygen treatment.ResultsThe duration of antibiotic treatment was significantly shorter in the combi...
Source: Traditional and Kampo Medicine - January 6, 2020 Category: Complementary Medicine Authors: Genzo Yamasaki, Daisuke Suzuki, Ayako Ose, Takahiko Ono Tags: ORIGINAL ARTICLE Source Type: research

Corrigendum
Traditional&Kampo Medicine, EarlyView. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 17, 2019 Category: Complementary Medicine Tags: CORRIGENDUM Source Type: research

Issue Information
Traditional&Kampo Medicine, Volume 6, Issue 3, Page 113-114, December 2019. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 1, 2019 Category: Complementary Medicine Tags: ISSUE INFORMATION Source Type: research

Alopecia universalis successfully treated with kenchuto groups in a pediatric patient
ConclusionFor alopecia in children, regional immunotherapy has been recommended in the treatment guidelines. However, the condition can recur after discontinuation of treatment and there is no treatment uniformity. The present findings suggest that Kampo medicine might be appropriate for alopecia universalis considering treatment continuity and safety. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 1, 2019 Category: Complementary Medicine Authors: Yasuhito Irie, Hajime Nakae, Naoko Hasunuma, Miwa Hebiguchi, Yuko Hiroshima, Yuko Okada, Hiroaki Ito Tags: CASE REPORT Source Type: research

Modulating effects of a decoction of a traditional Japanese herbal formula, hochuekkito (with Hedysari radix and Atractylodis rhizoma), on the local mucosal immune system of aged mice
ConclusionsHochuekkito with Hedysari radix and Atractylodis rhizoma modulates systemic and local mucosal immune systems in different ways. The formula encourages induction and recruitment of regulatory T lymphocytes and M2 macrophages in genital tract and lung, respectively, at the higher dose. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 1, 2019 Category: Complementary Medicine Authors: Mieko Kajita, Kayako Saso, Yosuke Tanaka, Takayuki Nagai, Hiroaki Kiyohara Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
Traditional&Kampo Medicine, Volume 6, Issue 3, Page 113-114, December 2019. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - December 1, 2019 Category: Complementary Medicine Tags: ISSUE INFORMATION Source Type: research

Identification of Chochukei (Zhang Zhongjing) as the revolutionist of decoctions
ConclusionFrom an examination of the existing pharmaceutical literature, we could establish that Chochukei developed decoctions that abstract the essence from crude drugs by adding water. He recognized that decoctions were more effective than pills and powders, the main medication in earlier times. We deduce that he was the ‘revolutionist of decoctions’ who developed and established the form of decoctions. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - November 27, 2019 Category: Complementary Medicine Authors: Toshinori Kawamoto, Hiroaki Nishijima, Masako Ohishi, Kazuto Isuzugawa, Ryuji Furihata, Yukio Nemoto Tags: ORIGINAL ARTICLE Source Type: research

Estimated incidence per population of adverse drug reactions to Kampo medicines from the Japanese adverse drug event report database (JADER)
ConclusionEstimation of the incidence of ADRs caused by Kampo medicines could be a prelude to a new risk management plan, and may focus attention on formulations and crude drug components associated with previously unindicated risks. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - November 21, 2019 Category: Complementary Medicine Authors: Ichiro Arai, Yusuke Harada, Hiroshi Koda, Kiichiro Tsutani, Yoshiharu Motoo Tags: ORIGINAL ARTICLE Source Type: research

Modulating effects of a decoction of a traditional Japanese herbal formula, hochuekkito (with Hedysari radix and Atractylodis rhizoma), on the local mucosal immune system of aged mice
ConclusionsHochuekkito with Hedysari radix and Atractylodis rhizoma modulates systemic and local mucosal immune systems in different ways. The formula encourages induction and recruitment of regulatory T lymphocytes and M2 macrophages in genital tract and lung, respectively, at the higher dose. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - November 1, 2019 Category: Complementary Medicine Authors: Mieko Kajita, Kayako Saso, Yosuke Tanaka, Takayuki Nagai, Hiroaki Kiyohara Tags: ORIGINAL ARTICLE Source Type: research

Alopecia universalis successfully treated with kenchuto groups in a pediatric patient
ConclusionFor alopecia in children, regional immunotherapy has been recommended in the treatment guidelines. However, the condition can recur after discontinuation of treatment and there is no treatment uniformity. The present findings suggest that Kampo medicine might be appropriate for alopecia universalis considering treatment continuity and safety. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - October 31, 2019 Category: Complementary Medicine Authors: Yasuhito Irie, Hajime Nakae, Naoko Hasunuma, Miwa Hebiguchi, Yuko Hiroshima, Yuko Okada, Hiroaki Ito Tags: CASE REPORT Source Type: research

Development of a medical education program with abdominal palpation simulators to support the understanding of traditional Japanese (kampo) medicine in beginners
ABSTRACTAimTraditional Japanese (kampo) medicine has recently been included in the medical education curriculum in Japan; hence, an education program in kampo physical examination for beginners is needed. The aim of the present study was to develop an education program using a simulator of kampo abdominal palpation that would enable beginners to acquire this skill, and to assess the effectiveness and usefulness of the education program.MethodsFirst, we conducted a preliminary trial. Fifteen beginners received a lecture about abdominal findings and the associated representative kampo formulas and underwent a simulator palpa...
Source: Traditional and Kampo Medicine - October 15, 2019 Category: Complementary Medicine Authors: Ryutaro Arita, Takehiro Numata, Natsumi Saito, Shin Takayama, Takafumi Togashi, Soichiro Kaneko, Akiko Kikuchi, Minoru Ohsawa, Tetsuharu Kamiya, Michiaki Abe, Tadashi Ishii Tags: ORIGINAL ARTICLE Source Type: research

Network analysis of kampo formulas based on crude drug composition and indications
ConclusionThe networks of kampo formulas as well as crude drugs and indications were successfully obtained, which may help to facilitate our understanding of kampo formulas and crude drugs. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - October 15, 2019 Category: Complementary Medicine Authors: Makito Oku Tags: ORIGINAL ARTICLE Source Type: research

Development of a medical education program with abdominal palpation simulators to support the understanding of traditional Japanese (kampo) medicine in beginners
ABSTRACTAimTraditional Japanese (kampo) medicine has recently been included in the medical education curriculum in Japan; hence, an education program in kampo physical examination for beginners is needed. The aim of the present study was to develop an education program using a simulator of kampo abdominal palpation that would enable beginners to acquire this skill, and to assess the effectiveness and usefulness of the education program.MethodsFirst, we conducted a preliminary trial. Fifteen beginners received a lecture about abdominal findings and the associated representative kampo formulas and underwent a simulator palpa...
Source: Traditional and Kampo Medicine - October 15, 2019 Category: Complementary Medicine Authors: Ryutaro Arita, Takehiro Numata, Natsumi Saito, Shin Takayama, Takafumi Togashi, Soichiro Kaneko, Akiko Kikuchi, Minoru Ohsawa, Tetsuharu Kamiya, Michiaki Abe, Tadashi Ishii Tags: ORIGINAL ARTICLE Source Type: research

Network analysis of kampo formulas based on crude drug composition and indications
ConclusionThe networks of kampo formulas as well as crude drugs and indications were successfully obtained, which may help to facilitate our understanding of kampo formulas and crude drugs. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - October 15, 2019 Category: Complementary Medicine Authors: Makito Oku Tags: ORIGINAL ARTICLE Source Type: research

Effects of kampo medicine keishikashakuyakuto on large intestine disease in mice
ConclusionKeishikashakuyakuto may be effective for IBS and IBD. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - October 11, 2019 Category: Complementary Medicine Authors: Yoshiyuki Kimura Tags: ORIGINAL ARTICLE Source Type: research

Gingyogedokusan versus oseltamivir for the treatment of influenza: Bayesian inference using the Markov chain Monte Carlo method with prior pilot study data
ConclusionAccording to Bayesian analysis, GGGS appears to have superiority over oseltamivir in resolving symptoms, although fever may resolve earlier with oseltamivir use. This is a proof of concept study, to encourage further research into the efficacy of GGGS for the treatment of influenza. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - October 8, 2019 Category: Complementary Medicine Authors: Kentaro Iwata, Takashi Nishimoto, Kumi Higasa, Seiichiro Usuki, Chisato Miyakoshi Tags: ORIGINAL ARTICLE Source Type: research

Pharmacological effects of yokukansan on behavioral and psychological symptoms of dementia
ConclusionYKS is expected to be useful in treating and/or preventing BPSD. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - September 9, 2019 Category: Complementary Medicine Authors: Nobuaki Egashira, Katsunori Iwasaki Tags: REVIEW Source Type: research

Effect of kamikihito on platelet count: Retrospective pilot study
This study assessed the effect of the kampo medicine kamikihito (KKT) on platelet count irrespective of type of illness.MethodsA single ‐center, retrospective pilot study was performed from March 2014 to March 2017. The subjects were patients who received KKT treatment and had blood samples collected in the 2 weeks prior to treatment initiation and ≤9 weeks after treatment completion at Toyama University Hospital.ResultsA total of 16 patients were identified as potential subjects, and their medical records were assessed. Their diagnoses were patent ear canal, insomnia, idiopathic thrombocytopenic purpura...
Source: Traditional and Kampo Medicine - September 6, 2019 Category: Complementary Medicine Authors: Tatsuya Nogami, Atsushi Kato, Yudai Ishikawa, Nobukazu Ryu, Isao Adachi Tags: ORIGINAL ARTICLE Source Type: research

Obstacles to the use of complementary and alternative medicine by primary care physicians: Preliminary study
ConclusionVarious factors interfere in the use of complementary and alternative medicine by primary care physicians. Approaches to overcome lack of education and insufficient collaboration among regional health professionals need to be developed. Future studies are needed to generalize the present findings in order to enhance integrative medicine and the utilization of complementary and alternative medicine in primary care settings. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - August 23, 2019 Category: Complementary Medicine Authors: Ryosuke Sugito, Daisuke Son Tags: SHORT COMMUNICATION Source Type: research

Issue Information
Traditional&Kampo Medicine, Volume 6, Issue 2, Page 47-48, August 2019. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - August 4, 2019 Category: Complementary Medicine Tags: ISSUE INFORMATION Source Type: research

Kampo therapy for idiopathic interstitial pneumonia (report 2): Gradual decrease in KL ‐6
ConclusionKampo therapy could be effective in improving the prognosis of IIP, partly due to inhibition of lung inflammation. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - July 9, 2019 Category: Complementary Medicine Authors: Yukihiko Homma, Yoshinori Ohtsuka Tags: ORIGINAL ARTICLE Source Type: research

Effect of Lactobacillus paracasei A221 ‐fermented ginseng on impaired spatial memory in a rat model with cerebral ischemia and β‐amyloid injection
ConclusionFG improved spatial memory impairment in CI + A β‐operated rats. The effect of FG might be attributed to the amelioration of apoptotic neuronal cell death and the inactivation of microglia. FG is a more useful treatment for patients with cognitive dysfunction than non‐FG. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - May 31, 2019 Category: Complementary Medicine Authors: Masaki Nagao, Satoshi Yamano, Naoki Imagawa, Kentaro Igami, Toshitsugu Miyazaki, Hisatomi Ito, Takuya Watanabe, Kaori Kubota, Shutaro Katsurabayashi, Katsunori Iwasaki Tags: ORIGINAL ARTICLE Source Type: research

Daisaikoto for shoulder stiffness and related changes in stool condition: Retrospective study
ABSTRACTAimDaisaikoto has been used for the treatment of shoulder stiffness and abdominal distention with constipation, which makes stool changes associated with the prescription a concern. The aim of this retrospective observational study was to investigate the effect of daisaikoto on shoulder stiffness and the relation between its effects on stiffness relief and stool condition.MethodsWe reviewed the medical records of middle ‐aged women who were treated with daisaikoto for menopause‐like symptoms and shoulder stiffness from December 2014 through November 2015 at Red Cross Maebashi Hospital. Two or 4 weeks aft...
Source: Traditional and Kampo Medicine - May 16, 2019 Category: Complementary Medicine Authors: Minoru Ohsawa, Shin Takayama, Akiko Kikuchi, Ryutaro Arita, Natsumi Saito, Yuka Ikeno, Hitoshi Nishikawa, Hiroyo Sasaki, Michiyo Kojima, Masayuki Shimizu, Takehiro Numata, Kota Ishizawa, Tadashi Ishii Tags: SHORT COMMUNICATION Source Type: research

Effect of hangebyakujutsutemmato on pregabalin ‐induced dizziness in a rat model of neuropathic pain
This study investigated the efficacy of hangebyakujutsutemmato (HBT) in alleviating disturbances of equilibrium using a rat pregabalin model of neuropathic pain with dizziness. Pregabalin is effective for treating neuropathic pain, but some patients cannot tolerate continued treatment owing to dizziness resulting from pregabalin, especially shortly after beginning treatment. HBT is a Japanese kampo medicine that is used to treat dizziness.MethodsRats with chronic constriction injury of the sciatic nerve (Bennett and Xie model) underwent the beam balance test to evaluate their sense of equilibrium. The animals were divided ...
Source: Traditional and Kampo Medicine - May 10, 2019 Category: Complementary Medicine Authors: Kunitaro Watanabe, Kumi Moriyama, Joho Tokumine, Tomoko Yorozu Tags: ORIGINAL ARTICLE Source Type: research

Kampo medicine resolves a case of polypharmacy with improvement sustained for 10 years
ConclusionBy introducing kampo medicine, we were able to reduce the patient's daily regimen from 13 to 2 medications. A pharmaceutical cost estimate indicated savings of approximately ¥1m over the past 10 years. Thus, use of kampo medicine can resolve polypharmacy and potentially reduce pharmaceutical costs. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - April 25, 2019 Category: Complementary Medicine Authors: Tatsuya Nogami, Makoto Fujimoto, Hidetoshi Watari, Yoshiyuki Kimbara, Naotoshi Shibahara, Yutaka Shimada Tags: CASE REPORT Source Type: research

Therapeutic effects of shikonin on skin lesions in mouse models of allergic dermatitis and wound
ConclusionShikonin can be used as a new therapeutic agent for the treatment of allergic dermatitis including atopic dermatitis. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - April 10, 2019 Category: Complementary Medicine Authors: Keiichi Kadoyama, Mariko Takenokuchi, Kenji Matsuura, Hiroaki Shichiri, Aimi Watanabe, Hirotsugu Yamaguchi, Hisashi Takahashi, Hiromi Takano ‐Ohmuro, Taizo Taniguchi Tags: ORIGINAL ARTICLE Source Type: research

Hainosan (painongsan) suppresses the biofilm formation of Porphyromonas gingivalis and Prevotella intermedia in vitro
ConclusionHNS may be useful for the treatment ofPorphyromonas gingivalis andPrevotella intermedia‐induced periodontitis because of the inhibition of bacterial biofilm formation. (Source: Traditional and Kampo Medicine)
Source: Traditional and Kampo Medicine - April 4, 2019 Category: Complementary Medicine Authors: Masaaki Minami, Hiroshi Takase, Masayo Taira, Toshiaki Makino Tags: ORIGINAL ARTICLE Source Type: research