Application of Mono and Trinuclear Cyclometalated Iridium (III) Complexes in Differential Bacterial Imaging and Antimicrobial Photodynamic therapy
Chemistry. 2024 Apr 23:e202400646. doi: 10.1002/chem.202400646. Online ahead of print.ABSTRACTThe application of transition metal complexes for antimicrobial photodynamic therapy (PDT) has emerged as an attractive alternative in mitigating a broad range of bacterial pathogens, including multidrug-resistant pathogens. In view of their photostability, long excited-state lifetimes, and tunable emission properties, transition metal complexes also contribute as bioimaging agents. In the present work, we designed mono and trinuclear cyclometalated iridium(III) complexes to explore their imaging application and antibacterial pote...
Source: Chemistry - April 23, 2024 Category: Chemistry Authors: Bishnu Das Prakash Biswas Amirul Islam Mallick Parna Gupta Source Type: research
Extent of Virulence and Antibiotic Resistance Genes in Helicobacter pylori and Campylobacteria
Curr Microbiol. 2024 Apr 23;81(6):154. doi: 10.1007/s00284-024-03653-5.ABSTRACTHelicobacter pylori, a member of the clade campylobacteria, is the leading cause of chronic gastritis and gastric cancer. Virulence and antibiotic resistance of H. pylori are of great concern to public health. However, the relationship between virulence and antibiotic resistance genes in H. pylori in relation to other campylobacteria remains unclear. Using the virulence and comprehensive antibiotic resistance databases, we explored all available 354 complete genomes of H. pylori and compared it with 90 species of campylobacteria for virulence an...
Source: Current Microbiology - April 23, 2024 Category: Microbiology Authors: R Shyama Prasad Rao Sudeep D Ghate Larina Pinto Prashanth Suravajhala Prakash Patil Praveenkumar Shetty Nagib Ahsan Source Type: research
Application of Mono and Trinuclear Cyclometalated Iridium (III) Complexes in Differential Bacterial Imaging and Antimicrobial Photodynamic therapy
Chemistry. 2024 Apr 23:e202400646. doi: 10.1002/chem.202400646. Online ahead of print.ABSTRACTThe application of transition metal complexes for antimicrobial photodynamic therapy (PDT) has emerged as an attractive alternative in mitigating a broad range of bacterial pathogens, including multidrug-resistant pathogens. In view of their photostability, long excited-state lifetimes, and tunable emission properties, transition metal complexes also contribute as bioimaging agents. In the present work, we designed mono and trinuclear cyclometalated iridium(III) complexes to explore their imaging application and antibacterial pote...
Source: Chemistry - April 23, 2024 Category: Chemistry Authors: Bishnu Das Prakash Biswas Amirul Islam Mallick Parna Gupta Source Type: research
Design of a multi-epitope-based vaccine candidate against Bovine Genital Campylobacteriosis using a reverse vaccinology approach
Bovine Genital Campylobacteriosis (BGC), a worldwide distributed venereal disease caused by Campylobacter fetus subsp. venerealis (Cfv), has a relevant negative economic impact in cattle herds. The control of BGC... (Source: BMC Veterinary Research)
Source: BMC Veterinary Research - April 19, 2024 Category: Veterinary Research Authors: Marta Filipa Silva, Gon çalo Pereira, Luísa Mateus, Luís Lopes da Costa and Elisabete Silva Tags: Research Source Type: research
Etiology of infantile acute gastro-enteritis in usual practice in hospital
Med Mal Infect. 1984 Jun;14(6):342-346. doi: 10.1016/S0399-077X(84)80070-0. Epub 2005 May 26.ABSTRACTThe authors report the results of a study of enteric disease etiology from chilfren during one year. These study is about 155 diarrheas, 16 from them content leukocytes. Rotavirus are discovered in 38,1 % diarrheas without leukocytes. Between the bacteria isolated, Salmonellaare the most frequently enteric bacterias. After, Campylobacter, E. colientero pathogenic. The isolation of Yersinia enterocoliticaand Shigellaare frequentless. A particular mention about the associations : rotavirus - bacterias, and about the high freq...
Source: Medecine et Maladies Infectieuses - April 15, 2024 Category: Infectious Diseases Authors: J P Hebert R Caillet Source Type: research
Virulence Genes, Antimicrobial Resistance, and Genotypes of Campylobacter jejuni Isolated from Chicken Slaughterhouses in South Korea
Foodborne Pathogens and Disease, Ahead of Print. (Source: Foodborne Pathogens and Disease)
Source: Foodborne Pathogens and Disease - April 12, 2024 Category: Food Science Authors: Jiyeon Jeong Ji-Youn Lee Jin-San Moon Min-Su Kang Sung-Il Kang O-Mi Lee So-Hee Lee Yong-Kuk Kwon Myeongju Chae Seongbeom Cho Source Type: research
Time, temperature and media: the three keys to improve the recovery of Campylobacter fetus subsp. venerealis from preputial bull samples
AbstractThe isolation ofCampylobacter fetus subsp.venerealis (Cfv) from clinical samples is the gold standard for confirming cases of bovine genital campylobacteriosis, an important cause of infertility in cattle and a potential public health concern. Furthermore, isolation is also necessary for the development of autologous vaccines, characterization of strains for antimicrobial susceptibility patterns, etc. Nevertheless, the sensitivity of culture methods is usually low, and there is no standardized protocol to maximize the recovery of Cfv from clinical samples. The aim of the current study is to design a protocol for th...
Source: Veterinary Research Communications - April 10, 2024 Category: Veterinary Research Source Type: research
Hemophagocytic lymphohistiocytosis and myopericarditis induced by campylobacter: a case report
We report a rare case of HLH... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 8, 2024 Category: Infectious Diseases Authors: Chia Hua Chang and Chih-Chuan Kao Tags: Case Report Source Type: research
Characterization of the oral microbiota and the relationship of the oral microbiota with the dental and periodontal status in children and adolescents with nonsyndromic cleft lip and palate. Systematic literature review and meta-analysis
ConclusionIn the microbiota, there was a great diversity of microorganisms that can vary according to the type of fissure and surgical interventions predisposing patients to a greater probability of dental caries, it is important to take into account the technique used to describe the oral microbiota in order to be able to compare the different studies.Clinical relevanceStudying the microbiota and the relationship of dental caries and periodontal status in children and adolescents with cleft lip and palate can facilitate the comprehensive care of patients with these conditions. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - April 8, 2024 Category: Dentistry Source Type: research
Exploring the association of weather variability on Campylobacter - A systematic review
DISCUSSION: This review explores what is known about the influence of weather events on Campylobacter and identifies previously underreported negative associations between relative humidity and sunshine on Campylobacter infections. Future research should explore pathogen-specific estimates of risk, which can be used to influence public health strategies, improve source attribution and causal pathways, and project disease burden due to climate change.PMID:38582433 | DOI:10.1016/j.envres.2024.118796 (Source: Environmental Research)
Source: Environmental Research - April 6, 2024 Category: Environmental Health Authors: Erika Austhof Shaylee Warner Kathryn Helfrich Kristen Pogreba-Brown Heidi E Brown Yann C Klimentidis Elaine Scallan Walter Rachel H Jervis Alice E White Source Type: research
Structural and biochemical analysis of penicillin-binding protein 2 from Campylobacter jejuni
Biochem Biophys Res Commun. 2024 Mar 30;710:149859. doi: 10.1016/j.bbrc.2024.149859. Online ahead of print.ABSTRACTPenicillin-binding protein 2 (PBP2) plays a key role in the formation of peptidoglycans in bacterial cell walls by crosslinking glycan chains through transpeptidase activity. PBP2 is also found in Campylobacter jejuni, a pathogenic bacterium that causes food-borne enteritis in humans. To elucidate the essential structural features of C. jejuni PBP2 (cjPBP2) that mediate its biological function, we determined the crystal structure of cjPBP2 and assessed its protein stability under various conditions. cjPBP2 ado...
Source: Biochemical and Biophysical Research communications - April 6, 2024 Category: Biochemistry Authors: Hong Joon Choi Dong Uk Ki Sung-Il Yoon Source Type: research
Structural and biochemical analysis of penicillin-binding protein 2 from Campylobacter jejuni
Biochem Biophys Res Commun. 2024 Mar 30;710:149859. doi: 10.1016/j.bbrc.2024.149859. Online ahead of print.ABSTRACTPenicillin-binding protein 2 (PBP2) plays a key role in the formation of peptidoglycans in bacterial cell walls by crosslinking glycan chains through transpeptidase activity. PBP2 is also found in Campylobacter jejuni, a pathogenic bacterium that causes food-borne enteritis in humans. To elucidate the essential structural features of C. jejuni PBP2 (cjPBP2) that mediate its biological function, we determined the crystal structure of cjPBP2 and assessed its protein stability under various conditions. cjPBP2 ado...
Source: Cell Research - April 6, 2024 Category: Cytology Authors: Hong Joon Choi Dong Uk Ki Sung-Il Yoon Source Type: research
Exploring the association of weather variability on Campylobacter - A systematic review
DISCUSSION: This review explores what is known about the influence of weather events on Campylobacter and identifies previously underreported negative associations between relative humidity and sunshine on Campylobacter infections. Future research should explore pathogen-specific estimates of risk, which can be used to influence public health strategies, improve source attribution and causal pathways, and project disease burden due to climate change.PMID:38582433 | DOI:10.1016/j.envres.2024.118796 (Source: Environmental Research)
Source: Environmental Research - April 6, 2024 Category: Environmental Health Authors: Erika Austhof Shaylee Warner Kathryn Helfrich Kristen Pogreba-Brown Heidi E Brown Yann C Klimentidis Elaine Scallan Walter Rachel H Jervis Alice E White Source Type: research
Structural and biochemical analysis of penicillin-binding protein 2 from Campylobacter jejuni
Biochem Biophys Res Commun. 2024 Mar 30;710:149859. doi: 10.1016/j.bbrc.2024.149859. Online ahead of print.ABSTRACTPenicillin-binding protein 2 (PBP2) plays a key role in the formation of peptidoglycans in bacterial cell walls by crosslinking glycan chains through transpeptidase activity. PBP2 is also found in Campylobacter jejuni, a pathogenic bacterium that causes food-borne enteritis in humans. To elucidate the essential structural features of C. jejuni PBP2 (cjPBP2) that mediate its biological function, we determined the crystal structure of cjPBP2 and assessed its protein stability under various conditions. cjPBP2 ado...
Source: Biochemical and Biophysical Research communications - April 6, 2024 Category: Biochemistry Authors: Hong Joon Choi Dong Uk Ki Sung-Il Yoon Source Type: research
Intestinal Colonization by < em > Campylobacter jejuni < /em > , < em > Clostridium difficile < /em > , and < em > Clostridium perfringens < /em > among Commensal < em > Rattus norvegicus < /em > in the Urban Areas of Tehran, Iran
CONCLUSION: According to the findings, rats are the main reservoirs for diseases. Therefore, rodent control coupled with the implementation of surveillance systems should be prioritized for urban health.PMID:38572169 | PMC:PMC10990632 | DOI:10.1155/2024/2929315 (Source: Biomed Res)
Source: Biomed Res - April 4, 2024 Category: Research Authors: Taher Azimi Sina Nasrollahian Sahar Sabour Mehrdad Mosadegh Nahal Hadi Leila Azimi Fatemeh Fallah Mohammad Reza Pourmand Source Type: research
