Emergence of Campylobacter fetus bacteraemias in the last decade, France
(Source: Infection)
Source: Infection - February 24, 2024 Category: Infectious Diseases Source Type: research
Gene expression profile of Campylobacter jejuni in response to macrolide antibiotics
Arch Microbiol. 2024 Feb 23;206(3):117. doi: 10.1007/s00203-024-03849-0.ABSTRACTCampylobacter jejuni is a foodborne pathogen that causes gastroenteritis in humans and has developed resistance to various antibiotics. The primary objective of this research was to examine the network of antibiotic resistance in C. jejuni. The study involved the wild and antibiotic-resistant strains placed in the presence and absence of antibiotics to review their gene expression profiles in response to ciprofloxacin via microarray. Differentially expressed genes (DEGs) analysis and Protein-Protein Interaction (PPI) Network studies were perfor...
Source: Archives of Microbiology - February 23, 2024 Category: Microbiology Authors: Hamed Rezayatmand Nafiseh Golestani Adele Sadat Haghighat Hoseini Elaheh Mousavialmaleki Mahsa Alem Donya Farzane Yegane Source Type: research
Microbiota changes: the unseen players in cervical cancer progression
In conclusion, a more profound understanding of the microbial landscape could elucidate the pathogenesis of cervical diseases and inform future strategies for diagnosis, prevention, and treatment.PMID:38389527 | PMC:PMC10881787 | DOI:10.3389/fmicb.2024.1352778 (Source: Cancer Control)
Source: Cancer Control - February 23, 2024 Category: Cancer & Oncology Authors: W M Fong Amaris Paulo Pimentel de Assump ção Leonardo Jacomo Valadares Fabiano Cordeiro Moreira Source Type: research
Gene expression profile of Campylobacter jejuni in response to macrolide antibiotics
Arch Microbiol. 2024 Feb 23;206(3):117. doi: 10.1007/s00203-024-03849-0.ABSTRACTCampylobacter jejuni is a foodborne pathogen that causes gastroenteritis in humans and has developed resistance to various antibiotics. The primary objective of this research was to examine the network of antibiotic resistance in C. jejuni. The study involved the wild and antibiotic-resistant strains placed in the presence and absence of antibiotics to review their gene expression profiles in response to ciprofloxacin via microarray. Differentially expressed genes (DEGs) analysis and Protein-Protein Interaction (PPI) Network studies were perfor...
Source: Archives of Microbiology - February 23, 2024 Category: Microbiology Authors: Hamed Rezayatmand Nafiseh Golestani Adele Sadat Haghighat Hoseini Elaheh Mousavialmaleki Mahsa Alem Donya Farzane Yegane Source Type: research
Specific gut pathobionts escape antibody coating and are enriched during flares in patients with severe Crohns disease
Conclusion
Distinct gut bacterial IgG2-coating was demonstrated in patients with severe CD and during disease flares. Co-occurrence of non-coated pathobionts with IgG2-coated bacteria points to an uncontrolled inflammatory condition in severe CD mediated via escape from antibody coating by two gut pathobionts. (Source: Gut)
Source: Gut - February 23, 2024 Category: Gastroenterology Authors: Eriksen, C., Danneskiold-Samsoe, N. B., Moll, J. M., Myers, P. N., Bondegaard, P. W., Vejrum, S., Hansen, T. B., Rosholm, L. B., Rausch, P., Allin, K. H., Jess, T., Kristiansen, K., Penders, J., Jonkers, D., Brix, S. Tags: Gut Inflammatory bowel disease Source Type: research
Comparative Molecular Virulence Typing and Antibiotic Resistance of Campylobacter Species at the Human –Animal–Environment Interface
Foodborne Pathogens and Disease, Ahead of Print. (Source: Foodborne Pathogens and Disease)
Source: Foodborne Pathogens and Disease - February 23, 2024 Category: Food Science Authors: Kashaf Yaseen Sultan Ali Sajjad-Ur Rahman Muhammad Sohail Sajid Source Type: research
Impact of the pandemic on various infectious diseases with different epidemiological patterns of seasonality, transmission and age
CONCLUSIONS: The impact of the pandemic is very different in these diseases. Pediatric and respiratory-transmitted seasonal viral infections are the ones that are most affected, but with different patterns of recovery to normality. Gastrointestinal bacterial infections suffer fewer variations, except for rotavirus. Gonorrhea do not interrupt its increasing trend seen in the pre-pandemic. Shingles show a slight post-pandemic increase. Several diseases with different epidemiological patterns have been studied for a sufficient period to observe how the acute phase of the pandemic emerges.PMID:38385502 (Source: Herpes)
Source: Herpes - February 22, 2024 Category: Infectious Diseases Authors: Juan Carlos Gasc ó-Laborda M Dolores Tirado-Balaguer Mar ía Gil-Fortuño Gabriela Dorina Deaconescu Oihana Sabalza-Bazt án Óscar Pérez-Olaso Iris G ómez-Alfaro Noelia Hern ández-Pérez Juan B Bellido-Blasco Source Type: research
Impact of the pandemic on various infectious diseases with different epidemiological patterns of seasonality, transmission and age
CONCLUSIONS: The impact of the pandemic is very different in these diseases. Pediatric and respiratory-transmitted seasonal viral infections are the ones that are most affected, but with different patterns of recovery to normality. Gastrointestinal bacterial infections suffer fewer variations, except for rotavirus. Gonorrhea do not interrupt its increasing trend seen in the pre-pandemic. Shingles show a slight post-pandemic increase. Several diseases with different epidemiological patterns have been studied for a sufficient period to observe how the acute phase of the pandemic emerges.PMID:38385502 (Source: Herpes)
Source: Herpes - February 22, 2024 Category: Infectious Diseases Authors: Juan Carlos Gasc ó-Laborda M Dolores Tirado-Balaguer Mar ía Gil-Fortuño Gabriela Dorina Deaconescu Oihana Sabalza-Bazt án Óscar Pérez-Olaso Iris G ómez-Alfaro Noelia Hern ández-Pérez Juan B Bellido-Blasco Source Type: research
EPINEST, an agent-based model to simulate epidemic dynamics in large-scale poultry production and distribution networks
by Francesco Pinotti, Jos é Lourenço, Sunetra Gupta, Suman Das Gupta, Joerg Henning, Damer Blake, Fiona Tomley, Tony Barnett, Dirk Pfeiffer, Md. Ahasanul Hoque, Guillaume Fournié
The rapid intensification of poultry production raises important concerns about the associated risks of zoonotic infections. Here, we introduce EPINEST (EPIdemic NEtwork Simulation in poultry Transportation systems): an agent-based modelling framework designed to simulate pathogen transmission within realistic poultry production and distribution networks. We provide example applications to broiler production in Bangladesh, but the modular stru...
Source: PLoS Computational Biology - February 21, 2024 Category: Biology Authors: Francesco Pinotti Source Type: research
Effect of the polysaccharide capsule and its heptose on the resistance of Campylobacter jejuni to innate immune defenses
This study shows that the wild-type capsule with its heptose is optimized to resist innate defenses in strain NCTC 11168 often via antagonistic effects of the capsule and its heptose. (Source: MicrobiologyOpen)
Source: MicrobiologyOpen - February 20, 2024 Category: Microbiology Authors: Matthew Myles,
Heba Barnawi,
Mahmoud Mahmoudpour,
Sargon Shlimon,
Adrienne Chang,
Daniel Zimmermann,
Chiwon Choi,
Najwa Zebian,
Carole Creuzenet Tags: ORIGINAL ARTICLE Source Type: research
Differential responses of selectively bred mussels (Perna canaliculus) to heat stress —survival, immunology, gene expression and microbiome diversity
This study aimed to identify general biomarkers of heat stress in P. canaliculus and to assess whether responses differed between genetically distinct selectively bred mussels. We exposed three families of selectively bred mussels (families A, B and C) to three seawater temperature regimes in the laboratory: 1) a “control” treatment (ambient 12°C), 2) a 26°C heat challenge with a subsequent recovery period, and 3) a sustained 26°C heat challenge with no recovery. We investigated whether the survival, immune response (hemocyte concentration and viability, oxidative stress and total antioxidant capacity), hemocyte gen...
Source: Frontiers in Physiology - February 15, 2024 Category: Physiology Source Type: research
Synthesis of 6-deoxy-d-ido-heptopyranose-containing fragments of the Campylobacter jejuni strain CG8486 capsular polysaccharide
We report here the synthesis of two fragments of the Campylobacter jejuni CG8486 strain CPS that contain a rare 6-deoxy-d-ido-heptopyranose residue and, in one target, two O-methyl phosphoramidate (MeOPN) motifs. The synthetic approach features the stereoselective construction of the β-d-ido-heptopyranoside linkage via glycosylation with a β-d-galacto-heptopyranoside donor followed by a one-pot sequential C-2 and C-3 inversion. During the syntheses, we uncovered a number of interesting conformational effects with regard to the 6-deoxy-ido-heptopyranose ring, the glycosidic linkage connecting the two monosaccharides, and ...
Source: Carbohydrate Research - February 14, 2024 Category: Genetics & Stem Cells Authors: V Narasimharao Thota Todd L Lowary Source Type: research
Synthesis of 6-deoxy-d-ido-heptopyranose-containing fragments of the Campylobacter jejuni strain CG8486 capsular polysaccharide
We report here the synthesis of two fragments of the Campylobacter jejuni CG8486 strain CPS that contain a rare 6-deoxy-d-ido-heptopyranose residue and, in one target, two O-methyl phosphoramidate (MeOPN) motifs. The synthetic approach features the stereoselective construction of the β-d-ido-heptopyranoside linkage via glycosylation with a β-d-galacto-heptopyranoside donor followed by a one-pot sequential C-2 and C-3 inversion. During the syntheses, we uncovered a number of interesting conformational effects with regard to the 6-deoxy-ido-heptopyranose ring, the glycosidic linkage connecting the two monosaccharides, and ...
Source: Carbohydrate Research - February 14, 2024 Category: Genetics & Stem Cells Authors: V Narasimharao Thota Todd L Lowary Source Type: research
Prevalence and antimicrobial resistance of bacterial enteropathogens in Crete, Greece, during 2011-2022
This study investigated the epidemiology and the antibiotic susceptibility of bacterial enteropathogens among diarrheal patients of all ages in Crete, Greece during 2011-2022. Stool specimens were tested by conventional cultural methods for Salmonella, Shigella, Campylobacter, diarrheagenic Escherichia coli (EPEC, STEC), Yersinia enterocolitica, Aeromonas species and Clostridioides difficile. Antimicrobial susceptibility was determined by the disk diffusion method for Enterobacterales, Campylobacter and Aeromonas, and by the gradient diffusion method for C. difficile. Of the 26,060 stool samples from patients of any age, 1...
Source: Acta Microbiologica et Immunologica Hungarica - February 12, 2024 Category: Microbiology Authors: Sofia Maraki Viktoria Eirini Mavromanolaki Dimitra Stafylaki Evangelia Iliaki-Giannakoudaki Anna Kasimati Source Type: research
