Structural Studies of ABC Transporters and Oligosaccharyltransferase
Wednesday Afternoon Lecture Series
Our understanding of the reaction mechanisms of membrane-embedded transport proteins or enzymes is insufficient. Dr. Kaspar Locher’s research group investigates two distinct types of membrane proteins, ATP-driven transporters and oligosaccaryltransferase (OST). In the past decade, his lab’s structural studies have defined the transmembrane folds of type 1 and type 2 ABC importers, ABC exporters, and of the catalytic subunit of OST. The first part of the lecture will focus on the mechanism of the bacterial ABC transporter BtuCD-F, which catalyzes vitamin B12 uptake into Gram-negative ...
Source: Videocast - All Events - May 27, 2014 Category: Journals (General) Tags: Upcoming Events Source Type: video
