Occupational exposure to Coxiella burnetii during cardiac surgery: A case report and review of the literature
We report a case of exposure to Coxiella burnetii in a surgical nurse who underwent an injury of her finger with a scalpel blade during a native aortic valve replacement with a bio-prosthetic cardiac valve conducted on a patient suffering from C. burnetii aortic endocarditis. Given the positivity of C. burnetii culture and PCR from the patient's aortic valve, she was prescribed prophylactic doxycycline 100 mg twice a day for 10 days. Q fever is an occupational zoonosis resulting usually of exposure to infected animals by inhalation of infected aerosols or consumption of contaminated raw milk. Apart from materno-foetal tran...
Source: Acta Microbiologica et Immunologica Hungarica - March 11, 2024 Category: Microbiology Authors: Patient Diwunga Matthieu Million Isabelle Ravaux Pierre Edouard Fournier Philippe Gautret Source Type: research

Occupational exposure to Coxiella burnetii during cardiac surgery: A case report and review of the literature
We report a case of exposure to Coxiella burnetii in a surgical nurse who underwent an injury of her finger with a scalpel blade during a native aortic valve replacement with a bio-prosthetic cardiac valve conducted on a patient suffering from C. burnetii aortic endocarditis. Given the positivity of C. burnetii culture and PCR from the patient's aortic valve, she was prescribed prophylactic doxycycline 100 mg twice a day for 10 days. Q fever is an occupational zoonosis resulting usually of exposure to infected animals by inhalation of infected aerosols or consumption of contaminated raw milk. Apart from materno-foetal tran...
Source: Acta Microbiologica et Immunologica Hungarica - March 11, 2024 Category: Microbiology Authors: Patient Diwunga Matthieu Million Isabelle Ravaux Pierre Edouard Fournier Philippe Gautret Source Type: research

Occupational exposure to Coxiella burnetii during cardiac surgery: A case report and review of the literature
We report a case of exposure to Coxiella burnetii in a surgical nurse who underwent an injury of her finger with a scalpel blade during a native aortic valve replacement with a bio-prosthetic cardiac valve conducted on a patient suffering from C. burnetii aortic endocarditis. Given the positivity of C. burnetii culture and PCR from the patient's aortic valve, she was prescribed prophylactic doxycycline 100 mg twice a day for 10 days. Q fever is an occupational zoonosis resulting usually of exposure to infected animals by inhalation of infected aerosols or consumption of contaminated raw milk. Apart from materno-foetal tran...
Source: Acta Microbiologica et Immunologica Hungarica - March 11, 2024 Category: Microbiology Authors: Patient Diwunga Matthieu Million Isabelle Ravaux Pierre Edouard Fournier Philippe Gautret Source Type: research

Occupational exposure to Coxiella burnetii during cardiac surgery: A case report and review of the literature
We report a case of exposure to Coxiella burnetii in a surgical nurse who underwent an injury of her finger with a scalpel blade during a native aortic valve replacement with a bio-prosthetic cardiac valve conducted on a patient suffering from C. burnetii aortic endocarditis. Given the positivity of C. burnetii culture and PCR from the patient's aortic valve, she was prescribed prophylactic doxycycline 100 mg twice a day for 10 days. Q fever is an occupational zoonosis resulting usually of exposure to infected animals by inhalation of infected aerosols or consumption of contaminated raw milk. Apart from materno-foetal tran...
Source: Acta Microbiologica et Immunologica Hungarica - March 11, 2024 Category: Microbiology Authors: Patient Diwunga Matthieu Million Isabelle Ravaux Pierre Edouard Fournier Philippe Gautret Source Type: research

Occupational exposure to Coxiella burnetii during cardiac surgery: A case report and review of the literature
We report a case of exposure to Coxiella burnetii in a surgical nurse who underwent an injury of her finger with a scalpel blade during a native aortic valve replacement with a bio-prosthetic cardiac valve conducted on a patient suffering from C. burnetii aortic endocarditis. Given the positivity of C. burnetii culture and PCR from the patient's aortic valve, she was prescribed prophylactic doxycycline 100 mg twice a day for 10 days. Q fever is an occupational zoonosis resulting usually of exposure to infected animals by inhalation of infected aerosols or consumption of contaminated raw milk. Apart from materno-foetal tran...
Source: Acta Microbiologica et Immunologica Hungarica - March 11, 2024 Category: Microbiology Authors: Patient Diwunga Matthieu Million Isabelle Ravaux Pierre Edouard Fournier Philippe Gautret Source Type: research

KPC-2 and VIM-1 producing Klebsiella pneumoniae ST39 high-risk clone isolated from a  clinical sample in Volos, Greece
In this study, we analyzed A165 strain K. pneumoniae ST39 isolated from a blood culture in November 2020. Whole-genome sequencing (WGS) was performed using Ion Torrent Platform, and resistance genes, virulence determinants, capsular types, insertion sequences, phage regions, and clustered regularly interspaced palindromic repeats (CRISPR) regions were detected by bioinformatic analysis. The molecular characterization revealed antimicrobial resistance genes, including sul2 for sulfamethoxazole; dfrA1 for trimethoprim; blaVIM-1 and blaKPC-2 for carbapenems; aac(6')-II for aminoglycosides; fosA for fosfomycin and aad1 for str...
Source: Acta Microbiologica et Immunologica Hungarica - March 7, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Pandora Tsolakidou Chatzivasileiou Panagiota Eleni Mylona Stella Mitka Source Type: research

KPC-2 and VIM-1 producing Klebsiella pneumoniae ST39 high-risk clone isolated from a  clinical sample in Volos, Greece
In this study, we analyzed A165 strain K. pneumoniae ST39 isolated from a blood culture in November 2020. Whole-genome sequencing (WGS) was performed using Ion Torrent Platform, and resistance genes, virulence determinants, capsular types, insertion sequences, phage regions, and clustered regularly interspaced palindromic repeats (CRISPR) regions were detected by bioinformatic analysis. The molecular characterization revealed antimicrobial resistance genes, including sul2 for sulfamethoxazole; dfrA1 for trimethoprim; blaVIM-1 and blaKPC-2 for carbapenems; aac(6')-II for aminoglycosides; fosA for fosfomycin and aad1 for str...
Source: Acta Microbiologica et Immunologica Hungarica - March 7, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Pandora Tsolakidou Chatzivasileiou Panagiota Eleni Mylona Stella Mitka Source Type: research

KPC-2 and VIM-1 producing Klebsiella pneumoniae ST39 high-risk clone isolated from a  clinical sample in Volos, Greece
In this study, we analyzed A165 strain K. pneumoniae ST39 isolated from a blood culture in November 2020. Whole-genome sequencing (WGS) was performed using Ion Torrent Platform, and resistance genes, virulence determinants, capsular types, insertion sequences, phage regions, and clustered regularly interspaced palindromic repeats (CRISPR) regions were detected by bioinformatic analysis. The molecular characterization revealed antimicrobial resistance genes, including sul2 for sulfamethoxazole; dfrA1 for trimethoprim; blaVIM-1 and blaKPC-2 for carbapenems; aac(6')-II for aminoglycosides; fosA for fosfomycin and aad1 for str...
Source: Acta Microbiologica et Immunologica Hungarica - March 7, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Pandora Tsolakidou Chatzivasileiou Panagiota Eleni Mylona Stella Mitka Source Type: research

KPC-2 and VIM-1 producing Klebsiella pneumoniae ST39 high-risk clone isolated from a  clinical sample in Volos, Greece
In this study, we analyzed A165 strain K. pneumoniae ST39 isolated from a blood culture in November 2020. Whole-genome sequencing (WGS) was performed using Ion Torrent Platform, and resistance genes, virulence determinants, capsular types, insertion sequences, phage regions, and clustered regularly interspaced palindromic repeats (CRISPR) regions were detected by bioinformatic analysis. The molecular characterization revealed antimicrobial resistance genes, including sul2 for sulfamethoxazole; dfrA1 for trimethoprim; blaVIM-1 and blaKPC-2 for carbapenems; aac(6')-II for aminoglycosides; fosA for fosfomycin and aad1 for str...
Source: Acta Microbiologica et Immunologica Hungarica - March 7, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Pandora Tsolakidou Chatzivasileiou Panagiota Eleni Mylona Stella Mitka Source Type: research

High rates of intestinal colonization with carbapenemase producing Enterobacteriaceae in  hematopoietic stem cell transplant recipients
Acta Microbiol Immunol Hung. 2024 Feb 21. doi: 10.1556/030.2024.02210. Online ahead of print.ABSTRACTCarbapenem resistant Enterobacteriaceae (CRE) are major human pathogens because, these cause high number of difficult-to-treat infections. Allogeneic hematopoietic stem cell transplant (AHSCT) recipients are highly exposed to these type of bacteria. The aim of our study was to investigate prevalence of CRE colonization in AHSCT patients and to determine genes encoding carbapenem resistance. A retrospective study conducted between January 2015 and December 2019, involved 55 patients colonized with CRE strains. We determined ...
Source: Acta Microbiologica et Immunologica Hungarica - February 21, 2024 Category: Microbiology Authors: Ikram Ayari Yosra Chebbi Anis Raddaoui Dorra Belloumi Siwar Frigui Rim Werhni Tarek Ben Othmen Nour Abedejlil Wafa Achour Source Type: research

Carbapenem-resistant Klebsiella pneumoniae in the Balkans: Clonal distribution and associated resistance determinants
Acta Microbiol Immunol Hung. 2024 Feb 21. doi: 10.1556/030.2024.02230. Online ahead of print.ABSTRACTCarbapenems are considered to be among the last line antibiotics against extended-spectrum β-lactamase producing Enterobacterales. Carbapenem-resistant Klebsiella pneumoniae (CRKP) has been frequently reported and its spread in Europe is indisputable and poses an enormous threat to hospitalized patients which is of growing concern. This review aims to record prevalence of CRKP in the Balkan region and to review the current knowledge about this life-threatening pathogen. In this review, we summarize data about clinical isol...
Source: Acta Microbiologica et Immunologica Hungarica - February 21, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Asimoula Kavvada Dimitrios Kavvadas Maria Anna Kyriazidi Konstantinos Eleftheriadis Sotirios Varlamis Vassilis Papaliagkas Stella Mitka Source Type: research

High rates of intestinal colonization with carbapenemase producing Enterobacteriaceae in  hematopoietic stem cell transplant recipients
Acta Microbiol Immunol Hung. 2024 Feb 21. doi: 10.1556/030.2024.02210. Online ahead of print.ABSTRACTCarbapenem resistant Enterobacteriaceae (CRE) are major human pathogens because, these cause high number of difficult-to-treat infections. Allogeneic hematopoietic stem cell transplant (AHSCT) recipients are highly exposed to these type of bacteria. The aim of our study was to investigate prevalence of CRE colonization in AHSCT patients and to determine genes encoding carbapenem resistance. A retrospective study conducted between January 2015 and December 2019, involved 55 patients colonized with CRE strains. We determined ...
Source: Acta Microbiologica et Immunologica Hungarica - February 21, 2024 Category: Microbiology Authors: Ikram Ayari Yosra Chebbi Anis Raddaoui Dorra Belloumi Siwar Frigui Rim Werhni Tarek Ben Othmen Nour Abedejlil Wafa Achour Source Type: research

Carbapenem-resistant Klebsiella pneumoniae in the Balkans: Clonal distribution and associated resistance determinants
Acta Microbiol Immunol Hung. 2024 Feb 21. doi: 10.1556/030.2024.02230. Online ahead of print.ABSTRACTCarbapenems are considered to be among the last line antibiotics against extended-spectrum β-lactamase producing Enterobacterales. Carbapenem-resistant Klebsiella pneumoniae (CRKP) has been frequently reported and its spread in Europe is indisputable and poses an enormous threat to hospitalized patients which is of growing concern. This review aims to record prevalence of CRKP in the Balkan region and to review the current knowledge about this life-threatening pathogen. In this review, we summarize data about clinical isol...
Source: Acta Microbiologica et Immunologica Hungarica - February 21, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Asimoula Kavvada Dimitrios Kavvadas Maria Anna Kyriazidi Konstantinos Eleftheriadis Sotirios Varlamis Vassilis Papaliagkas Stella Mitka Source Type: research

High rates of intestinal colonization with carbapenemase producing Enterobacteriaceae in  hematopoietic stem cell transplant recipients
Acta Microbiol Immunol Hung. 2024 Feb 21. doi: 10.1556/030.2024.02210. Online ahead of print.ABSTRACTCarbapenem resistant Enterobacteriaceae (CRE) are major human pathogens because, these cause high number of difficult-to-treat infections. Allogeneic hematopoietic stem cell transplant (AHSCT) recipients are highly exposed to these type of bacteria. The aim of our study was to investigate prevalence of CRE colonization in AHSCT patients and to determine genes encoding carbapenem resistance. A retrospective study conducted between January 2015 and December 2019, involved 55 patients colonized with CRE strains. We determined ...
Source: Acta Microbiologica et Immunologica Hungarica - February 21, 2024 Category: Microbiology Authors: Ikram Ayari Yosra Chebbi Anis Raddaoui Dorra Belloumi Siwar Frigui Rim Werhni Tarek Ben Othmen Nour Abedejlil Wafa Achour Source Type: research

Carbapenem-resistant Klebsiella pneumoniae in the Balkans: Clonal distribution and associated resistance determinants
Acta Microbiol Immunol Hung. 2024 Feb 21. doi: 10.1556/030.2024.02230. Online ahead of print.ABSTRACTCarbapenems are considered to be among the last line antibiotics against extended-spectrum β-lactamase producing Enterobacterales. Carbapenem-resistant Klebsiella pneumoniae (CRKP) has been frequently reported and its spread in Europe is indisputable and poses an enormous threat to hospitalized patients which is of growing concern. This review aims to record prevalence of CRKP in the Balkan region and to review the current knowledge about this life-threatening pathogen. In this review, we summarize data about clinical isol...
Source: Acta Microbiologica et Immunologica Hungarica - February 21, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Asimoula Kavvada Dimitrios Kavvadas Maria Anna Kyriazidi Konstantinos Eleftheriadis Sotirios Varlamis Vassilis Papaliagkas Stella Mitka Source Type: research