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Usefulness of the Lymphocyte Transformation Test in Botulinum Toxin type A allergy
J Investig Allergol Clin Immunol. 2023 Jul 10:0. doi: 10.18176/jiaci.0924. Online ahead of print.NO ABSTRACTPMID:37449404 | DOI:10.18176/jiaci.0924 (Source: Journal of Investigational Allergology and Clinical Immunology)
Source: Journal of Investigational Allergology and Clinical Immunology - July 14, 2023 Category: Allergy & Immunology Authors: M Giraldo Tugores M E Mart ínez Rodríguez C Fern ández Lozano J Mart ínez Botas B De la Hoz Caballer D Gonz ález de Olano S Terrados Cepeda Source Type: research

Permanent Brachial Plexus Birth Injury: Helsinki Shoulder Protocol
Semin Plast Surg DOI: 10.1055/s-0043-1768940Passive shoulder exercises from birth and ultrasound screening from 3 to 12 months. Botox is given to shoulder internal rotators and a bracing commenced, if alpha-angle exceeds 30°, or passive shoulder external rotation is below 70 degrees. Plexus reconstruction is recommended to children with root avulsion(s) on magnetic resonance imaging or 3-month Toronto Test Score < 3.5. Specific neurotization is recommended to children without avulsions, but lack of progress in healing. Shoulder dysplasia was diagnosed in 49% of 270 patients with permanent brachial plexus birth in...
Source: Seminars in Plastic Surgery - July 14, 2023 Category: Cosmetic Surgery Authors: Grahn, Petra P öyhiä, Tiina Nietosvaara, Yrj änä Tags: Review Article Source Type: research

Gastric per-oral endoscopic myotomy versus pyloric injection of botulinum toxin for the treatment of gastroparesis: our institutional experience and a systematic review of the literature
ConclusionGPOEM leads to significant improvement in GES percentages and GCSI scores postoperatively and is superior to Botox injection results reported in the literature. (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - July 10, 2023 Category: Surgery Source Type: research

Radiologically supervised bowel management program outcome in patients with chronic idiopathic constipation
ConclusionOur RS-BMP has been proven to be effective in treating CIC. The radiologically supervised use of Senna and enemas was the appropriate treatment in 96% of the patients. BD and megarectum were associated with unsuccessful outcomes. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - July 10, 2023 Category: Surgery Source Type: research

Botulinum toxin type A for genitofemoral neuralgia: A case report
Genitofemoral neuralgia is an uncommon pain disorder that could be resistant to conventional treatment. A 78-year-old woman with refractory right genitofemoral neuralgia was treated with BoNT/A subcutaneous injections; the treatment was performed three times with significant pain improvement, although temporary, and without adverse events. BoNT/A may be a promising alternative intervention in the setting of genitofemoral neuralgia refractory to oral and/or topical treatment. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - July 3, 2023 Category: Neurology Source Type: research

Preoperative manometric data can predict symptom improvement after per oral endoscopic myotomy for treatment of achalasia
ConclusionIn this study, achalasia type was not a predictive factor in need for further interventions or degree of symptom relief. While IRP was not predictive of need for further interventions, a higher IRP did predict better symptomatic relief postoperatively. This result is opposite that of other endoscopic treatment modalities. Therefore, patients with higher IRP on high-resolution manometry would likely benefit from myotomy which provides significant symptomatic relief postoperatively. (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - June 30, 2023 Category: Surgery Source Type: research

Botulinum toxin A and neuropathic pain: An update
Toxicon. 2023 Jun 27:107208. doi: 10.1016/j.toxicon.2023.107208. Online ahead of print.ABSTRACTBotulinum toxin type A is a widely used neurotoxin for the treatment of muscle hyperactivity such as dystonia and spasticity. Several clinical trials have also reported an efficacy of subcutaneous or intradermal administrations of botulinum toxin A on various neuropathic pain conditions including idiopathic trigeminal neuralgia and found that specific sensory phenotypes were predictors of the response. This narrative review summarizes the potential mechanisms of action, efficacy and safety of botulinum toxin A in neuropathic pain...
Source: Toxicon - June 29, 2023 Category: Toxicology Authors: A Spagna N Attal Source Type: research