We now know how Botox enters neurons and paralyses muscles
Molecular imaging shows that botulinum neurotoxin uses three receptors to enter neurons. The finding could help develop drugs to stop the toxin from infecting cells (Source: New Scientist - Health)
Source: New Scientist - Health - May 25, 2023 Category: Consumer Health News Source Type: research
Botulinum toxin type a in multimodal management of age-related macular degeneration and related diseases
Toxicon. 2023 May 18:107170. doi: 10.1016/j.toxicon.2023.107170. Online ahead of print.ABSTRACTAge related macular degeneration (AMD) is the major cause of visual loss in the aging population in the Western world. In past decade, intra ocular injections of anti-vascular endothelial growth factor (anti VEGF) pharmaceuticals have revolutionized therapy for exudative (edematous-wet) AMD and become standard practice for the near term. However repeated intra-ocular injections are required for years and long terms results have been limited. The pathogenesis of this condition is multifactorial involving genetic, ischemic, inflamm...
Source: Toxicon - May 20, 2023 Category: Toxicology Authors: Gary Borodic Md Source Type: research
