Botulinum toxin type a for great auricular neuralgia
We report a case of great auricular neuralgia treated with botulinum toxin type A subcutaneous injection with significant remission of pain. Botulinum toxin type A could be an effective and safe treatment in this setting; however, more studies are needed to confirm our results.PMID:37352981 | DOI:10.1016/j.toxicon.2023.107204 (Source: Toxicon)
Source: Toxicon - June 23, 2023 Category: Toxicology Authors: Yan Tereshko Christian Lettieri Enrico Belgrado Simone Dal Bello Gian Luigi Gigli Mariarosaria Valente Source Type: research

Botulinum toxin type a for great auricular neuralgia
We report a case of great auricular neuralgia treated with botulinum toxin type A subcutaneous injection with significant remission of pain. Botulinum toxin type A could be an effective and safe treatment in this setting; however, more studies are needed to confirm our results.PMID:37352981 | DOI:10.1016/j.toxicon.2023.107204 (Source: Toxicon)
Source: Toxicon - June 23, 2023 Category: Toxicology Authors: Yan Tereshko Christian Lettieri Enrico Belgrado Simone Dal Bello Gian Luigi Gigli Mariarosaria Valente Source Type: research

Intrathecal Injection of Botulinum Toxin Type A has an Analgesic Effect in Male Rats CCI Model by Inhibiting the Activation of Spinal P2X4R
This study found that intrathecal injection of botulinum toxin type A produced an excellent analgesic effect in a rat model of chronic constriction sciatic nerve injury and inhibited the activation of P2X4R, microglia, and astrocytes. The administration of a P2X4R activator can up-regulate the expression of P2X4R and eliminate the analgesic effect of intrathecal injection of botulinum toxin type A. In addition, we found that microglia and astrocytes in the spinal cord of rats injected with botulinum toxin type A were reactivated after administration of the P2X4R activator. Our results suggest that intrathecal injection of ...
Source: Neurochemical Research - June 19, 2023 Category: Neuroscience Authors: Wen-Ming Zhou Ze-Yuan Lei Yong-Qiang Shi Chao-Yang Gong Zhang Kai Nan Wei Lin-Na Wang Cheng-Jun Zhang Hai-Hong Zhang Source Type: research

Bleeding risk in female patients undergoing intravesical injection of onabotulinumtoxinA for overactive bladder: a Danish retrospective cohort study
ConclusionsWe suggest that BTX-A treatments might be classified as low-risk procedures. Discontinuation of antithrombotic therapy is not required in the perioperative management of this patient group. (Source: International Urogynecology Journal and Pelvic Floor Dysfunction)
Source: International Urogynecology Journal and Pelvic Floor Dysfunction - June 17, 2023 Category: OBGYN Source Type: research

Real-World, Retrospective, Multicenter, Observational Study on the Use of the First Liquid AbobotulinumtoxinA in Italy
CONCLUSIONS: Real-world data confirmed that aboBoNT-A is a fast, efficient, durable, reproducible, and easy-to-use drug which is also well tolerated in patients with family history of IMID.PMID:37316750 | DOI:10.1007/s13555-023-00951-x (Source: Pain Physician)
Source: Pain Physician - June 14, 2023 Category: Anesthesiology Authors: Carlo Di Gregorio Matteo Tretti-Clementoni Magda Belmontesi Marina Romagnoli Alessandro Innocenti Malvina Zanchi Lucia Leone Giovanni Damiani Ivano Iozzo Source Type: research

Real-World, Retrospective, Multicenter, Observational Study on the Use of the First Liquid AbobotulinumtoxinA in Italy
CONCLUSIONS: Real-world data confirmed that aboBoNT-A is a fast, efficient, durable, reproducible, and easy-to-use drug which is also well tolerated in patients with family history of IMID.PMID:37316750 | DOI:10.1007/s13555-023-00951-x (Source: Pain Physician)
Source: Pain Physician - June 14, 2023 Category: Anesthesiology Authors: Carlo Di Gregorio Matteo Tretti-Clementoni Magda Belmontesi Marina Romagnoli Alessandro Innocenti Malvina Zanchi Lucia Leone Giovanni Damiani Ivano Iozzo Source Type: research

Real-World, Retrospective, Multicenter, Observational Study on the Use of the First Liquid AbobotulinumtoxinA in Italy
ConclusionsReal-world data confirmed that aboBoNT-A is a fast, efficient, durable, reproducible, and easy-to-use drug which is also well tolerated in patients with family history of IMID. (Source: Dermatology and Therapy)
Source: Dermatology and Therapy - June 14, 2023 Category: Dermatology Source Type: research

OnabotulinumtoxinA improves oral aperture in patients with scleroderma: A small clinical trial
This study suggests that onabotulinumtoxinA is an efficacious short-term treatment for microstomia in scleroderma, and physicians should consider it to improve symptoms. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - June 8, 2023 Category: Dermatology Authors: Cristian D. Gonzalez, Jarod John Pamatmat, Kevin M. Burningham, Michelle Yang, Heather W. Goff Source Type: research

OnabotulinumtoxinA improves oral aperture in patients with scleroderma: A  small clinical trial
Reduced oral aperture (ROA), resulting from systemic sclerosis (SSc), is a debilitating condition with limited treatment options. Improvement in oral function has been reported with perioral administration of botulinum toxin type A. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - June 8, 2023 Category: Dermatology Authors: Cristian D. Gonzalez, Jarod John Pamatmat, Kevin M. Burningham, Michelle Yang, Heather W. Goff Tags: Original article Source Type: research

Botox Use in the Older Woman: An Advanced Bladder Treatment Option
This article focuses on challenges of caring for older women with urgency urinary incontinence (UUI), and asks how treatment algorithms for UUI could be tailored to the needs of older women.Recent FindingsUrgency urinary incontinence is highly prevalent among older women, and has significant health, social and economic impact for patients, caregivers and society. It is more difficult to treat among older women in part due to interaction with other geriatric syndromes and comorbidities. Also, the existing treatment algorithm, including anticholinergic medications as a mainstay of therapy, is less relevant to older patients ...
Source: Current Geriatrics Reports - June 2, 2023 Category: Geriatrics Source Type: research

Endoscopic ultrasound guided anal botox
Children's Hospital Colorado, USA; University of Colorado - Anschutz Medical Campus, USA; Phoenix Children's Hospital, USA; Emory University, USA. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - June 1, 2023 Category: Gastroenterology Authors: Brianne Shuler, Jaime Belkind-Gerson, Taylor Montminy, Paul Tran, Alexandra Kilgore, Jacob Mark Tags: Basic and Clinical Intestinal Disorders (BCID) Saturday, May 6, 2023 11:30 AM - 12:30 PM Source Type: research