[Long-term stability and relapse of deep bite correction:  a systematic review].
CONCLUSION:  Age at initiation of treatment and treatment technique are two factors impacting the long-term stability of deep overbite correction. PMID: 31241459 [PubMed - in process] (Source: L' Orthodontie Francaise)
Source: L' Orthodontie Francaise - June 1, 2019 Category: Dentistry Authors: Diouf JS, Beugre-Kouassi AML, Diop-Ba K, Badiane A, Ngom PI, Ouedraogo Y, Diagne F Tags: Orthod Fr Source Type: research

Digital Image Speckle Correlation to Optimize Botulinum Toxin Type A Injection: A Prospective, Randomized, Crossover Trial
Conclusions: This study demonstrates the benefits of using digital image speckle correlation in determining optimal botulinum toxin type A injection location. Digital analysis allows practitioners to better treat facial rhytides by eliminating subjective decisions regarding dose and site of injection. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, II. (Source: Plastic and Reconstructive Surgery)
Source: Plastic and Reconstructive Surgery - May 30, 2019 Category: Cosmetic Surgery Tags: Cosmetic: Original Articles Source Type: research

Botulinum toxin (Botox) A for reducing the appearance of facial wrinkles: a literature review of clinical use and pharmacological aspect.
Conclusion: Botox is good and safe medicine to reduce the appearance of facial wrinkles. PMID: 31114283 [PubMed] (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - May 24, 2019 Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research

Botulinum toxin type A intravesical injections for overactive bladder under local anaesthesia the causeway experience
Introduction: Overactive Bladder (OAB) and Detrusor Overactivity (DO) are associated with symptoms of urgency, frequency and nocturia, with or without incontinence. Botulinum Toxin has rapidly become established as a treatment option for an Overactive Bladder (OAB). (Source: Maturitas)
Source: Maturitas - May 14, 2019 Category: Primary Care Authors: Jacek Obrycki, Gerard Krystowski, Gemma Spence Tags: P50 Source Type: research

The Current Role of Botox in a Pediatric Neurogenic Bladder Condition
AbstractPurpose of ReviewThe neurogenic bladder is a medical term that describes a variety of bladder and sphincter dysfunctions. There are two major dangerous functional problems in a child with neurogenic bladder: high intravesical pressure in the storage phase and high pressure during urination. Two basic goals for urologic treatment in those children are protection of urinary tract from complications and improvement of continence in older children. This review focuses on the current role of botulinum toxin treatment in children with neurogenic bladder.Recent FindingsAt the beginning, treatment in this group of children...
Source: Current Bladder Dysfunction Reports - May 9, 2019 Category: Urology & Nephrology Source Type: research

Botulinum Toxin Modulates Posterior Parietal Cortex Activation in Post-stroke Spasticity of the Upper Limb
Post-stroke spasticity (PSS) is effectively treated with intramuscular botulinum toxin type A (BoNT-A), although the clinical improvement is likely mediated by changes at the central nervous system level. Using functional magnetic resonance imaging (fMRI) of the brain, this study aims to confirm and locate BoNT-A-related changes during motor imagery with the impaired hand in severe PSS. Temporary alterations in primary and secondary sensorimotor representation of the impaired upper limb were expected. Thirty chronic stroke patients with upper limb PSS undergoing comprehensive treatment including physiotherapy and indicat...
Source: Frontiers in Neurology - May 9, 2019 Category: Neurology Source Type: research

Application of botulinum toxin type A in gummy smile: case report
ABSTRACT Gummy smile is one of the major complaints of patients, due to its influence on the self-esteem. It is known that it has a multifactorial cause and can be present in the excessive vertical growth of the maxilla, excessive labial contraction, short upper lip and extrusion of the anterior teeth. The use of the botulinum toxin can be associated with additional treatments or be applied individually, according to the need of each patient. The goal of this research study was to present a clinical case using botulinum toxin type A as an alternative therapy to correct the gummy smile. A 22-year-old patient, presenting ver...
Source: RGO - Revista Gaucha de Odontologia - May 6, 2019 Category: Dentistry Source Type: research

Anal sphincter botulinum toxin injection in children with functional anorectal and colonic disorders: A large institutional study and review of the literature focusing on complications
Botulinum toxin (botox) is a commonly used treatment for functional anorectal and colonic disorders. Although generally regarded as safe, complications associated with botox injection into the anal sphincters in children with severe defecation disorders are not well described. We aimed to review our institutional experience and the existing literature to better understand the safety of this practice. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - May 3, 2019 Category: Surgery Authors: Devin R. Halleran, Peter L. Lu, Hira Ahmad, Michela M. Paradiso, Haley Lehmkuhl, Allison Akers, Alexandra Hallagan, Neetu Bali, Karla Vaz, Desalegn Yacob, Carlo Di Lorenzo, Marc A. Levitt, Richard J. Wood Source Type: research

Modified Selective Neurectomy for the Treatment of Post–Facial Paralysis Synkinesis
Conclusion: Modified selective neurectomy of the buccal and cervical divisions of the facial nerve is an effective long-term treatment for smile dysfunction in patients with post–facial paralysis synkinesis. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV. (Source: Plastic and Reconstructive Surgery)
Source: Plastic and Reconstructive Surgery - April 30, 2019 Category: Cosmetic Surgery Tags: Reconstructive: Head and Neck: Original Articles Source Type: research

Mandibular Vertical Growth Deficiency After Botulinum-Induced Hypotrophy of Masticatory Closing Muscles in Juvenile Nonhuman Primates
This study was approved by the Animal Experimental Ethics Committee of Southern Medical University, Guangzhou, China (2014-024). All experiments were performed under protocols to meet the requirements of the Association for Assessment and Accreditation of Laboratory Animal Care International and the Experimental Animal Center of Southern Medical University. Male cynomolgus monkeys (Macaca fascicularis) were used, preliminary power analysis being performed to get the proper sample size for three groups (G∗Power 3.1, Heinrich-Heine-Universität Düsseldorf, Germany; alpha = 0.05, power = 0.95; total N = 20 hem...
Source: Frontiers in Physiology - April 26, 2019 Category: Physiology Source Type: research

Intralesional Injection of Botulinum Toxin Type A Compared with Intralesional Injection of Corticosteroid for the Treatment of Hypertrophic Scar and Keloid: A Systematic Review and Meta-Analysis.
Authors: Bi M, Sun P, Li D, Dong Z, Chen Z Abstract BACKGROUND The optimal treatment for hypertrophic scar and keloid remains controversial. Therefore, the aim of this systematic review and meta-analysis was to compare the effectiveness of intralesional injection of botulinum toxin type A compared with placebo and intralesional injection of corticosteroid compared with placebo in patients with hypertrophic scar and keloid. MATERIAL AND METHODS Six databases were searched using Medical Subject Headings (MeSH) keywords and included Web of Science, PubMed, EMBASE, the Cochrane Library, WanFang, and CNKI from their inc...
Source: Medical Science Monitor - April 24, 2019 Category: Research Tags: Med Sci Monit Source Type: research

Use of botulinum toxin A in children with cerebral palsy.
Abstract BACKGROUND: For more than 20 years, intramuscular injections of botulinum toxin A have been an established treatment for spasticity in children with cerebral palsy. We investigated the proportion of children with cerebral palsy who receive such treatment in Norway and the guidelines that apply to the treatment. MATERIAL AND METHOD: Data from the five-year registration in the Cerebral Palsy Registry of Norway were used to investigate the proportion of children with cerebral palsy born in the period 1999-2010 treated with botulinum toxin A, and whether there were any variations in the proportion of chi...
Source: Tidsskrift for den Norske Laegeforening - April 24, 2019 Category: General Medicine Authors: Ross Raftemo AE, Mahendran A, Hollung SJ, Jahnsen RB, Lydersen S, Vik T, Andersen GL Tags: Tidsskr Nor Laegeforen Source Type: research

Intravesical electromotive administration of botulinum toxin type A in improving the bladder and bowel functions: Evidence for novel mechanism of action.
CONCLUSIONS: The presence of BoNTA in lower and upper spinal cord suggests the possibility of retrograde trans-axonal transfer of toxin to lower and upper neural pathways which may result in simultaneous improvement in bladder and bowel functions. PMID: 30998432 [PubMed - as supplied by publisher] (Source: Journal of Spinal Cord Medicine)
Source: Journal of Spinal Cord Medicine - April 20, 2019 Category: Orthopaedics Tags: J Spinal Cord Med Source Type: research

966 Botulinum toxin suppresses pro-fibrotic effects in hypertrophic scar fibroblasts
In this study, we investigated the inhibitory effect of BTX on HS-derived fibroblasts (HSFs) in vitro and explored the possible associated molecular mechanism by examining cell proliferation, cell migration, protein expression of scar-related factors, and intracellular signaling. (Source: Journal of Investigative Dermatology)
Source: Journal of Investigative Dermatology - April 20, 2019 Category: Dermatology Authors: M. An, G. Park, E. Park Tags: Tissue Regeneration and Wound Healing Source Type: research

Editorial: Botox for levator ani
(Source: Techniques in Coloproctology)
Source: Techniques in Coloproctology - April 16, 2019 Category: Surgery Source Type: research

Intra-articular botulinum toxin type A for treatment of knee osteoarthritis: Clinical trial.
Abstract In recent years, there is a growing interest in new medical applications of botulinum toxin, including pain control, osteoarthritis treatment, and wound healing. While clinical applications of botulinum toxin seem promising, existing evidence regarding the therapeutic effects is still inadequate. The aim was to assess the efficacy of a single injection of abobotulinumtoxin A into the knee joint cavity to reduce pain in elderly people. We carried out a single group clinical trial in a University Hospital. Thirty participants (24 women) more than 50 years of age with knee osteoarthritis were included. Diagn...
Source: Toxicon - April 14, 2019 Category: Toxicology Authors: Najafi S, Sanati E, Khademi M, Abdorrazaghi F, Mofrad RK, Rezasoltani Z Tags: Toxicon Source Type: research

Functional effects of botulinum toxin type A in the hip adductors and subsequent stretching in patients with hereditary spastic paraplegia.
CONCLUSION: Bilateral botulinum toxin A treatment and subsequent stretching of the hip adductors may improve gait and reactive lateral stepping in patients with pure hereditary spastic paraplegia. PMID: 30968942 [PubMed - as supplied by publisher] (Source: Journal of Rehabilitation Medicine)
Source: Journal of Rehabilitation Medicine - April 12, 2019 Category: Rehabilitation Tags: J Rehabil Med Source Type: research

Robot-assisted Heller myotomy for achalasia
Publication date: Available online 8 April 2019Source: Journal of Pediatric Surgery Case ReportsAuthor(s): Giulia Fusi, Francesco Molinaro, Francesco Ferrara, Edoardo Bindi, Chiara Pellegrino, Chiara Calani, Mario Messina, Rossella AngottiAbstractAchalasia is a rare neuromuscular esophageal disorder in children. There are many surgical options to treatment including botulinum toxin (Botox) injections, oral pharmacologic therapies with nitrates and calcium channel blockers, pneumatic dilation (PD), and surgical myotomy (open surgery, endoscopy, laparoscopy and recently robotic approach). In pediatric age, usually, Heller's ...
Source: Journal of Pediatric Surgery Case Reports - April 9, 2019 Category: Surgery Source Type: research

New Trends in Migraine Pharmacology: Targeting Calcitonin Gene –Related Peptide (CGRP) With Monoclonal Antibodies
This study aims at investigating the still poorly clear pathogenesis of migraine and the potential role of anti-CGRP mAbs in the scenario of prophylaxis of migraine. Introduction: Migraine Clinic Migraine consists in unilateral headache accompanied by a cluster of other sensory, autonomic and cognitive symptoms and it has been identified by the global burden of disease (GBD) study 2016 as the sixth most prevalent disorder and one of the main causes of disability all over the world, often occuring in working age and in young adult and middle-aged women (Collaborators, 2018). Hence, migraine represents a very serious...
Source: Frontiers in Pharmacology - April 9, 2019 Category: Drugs & Pharmacology Source Type: research

Thoracic Outlet Syndrome Treated With Injecting Botulinum Toxin Into Middle Scalene Muscle and Pectoral Muscle Interfascial Planes: A Case Report
Thoracic outlet compression syndrome is a complex syndrome of neurovascular compression at the superior thoracic aperture, thought to occur at 1 of 3 anatomical compartments: the interscalene triangle, the costoclavicular space, and the retropectoralis minor space. Injection into the middle interscalene muscle (ISM) and/or pectoralis muscle plane (PECS I and II) is gaining popularity because it provides significant symptomatic relief. A 44-year-old woman was diagnosed with thoracic outlet compression syndrome, with failed conservative therapy, including physical therapy. She refused surgical intervention. ISM and PECS I an...
Source: A&A Case Reports - April 1, 2019 Category: Anesthesiology Tags: Case Reports Source Type: research

Submandibular Gland Reduction Using Botulinum Toxin Type A for a Smooth Jawline
Source: Plastic and Reconstructive Surgery Global Open - April 1, 2019 Category: Cosmetic Surgery Tags: Viewpoint Source Type: research

Concomitant primary ovarian paraganglioma neuroendocrinal differentiated urothelial tumor in a BOTOX-injected bladder. A Case report
DiscussionIntravesical BCG is a standard adjuvant treatment for carcinoma in situ with 75% induced cystitis as a local side effect. The International Bladder Cancer Group’s recommendation for BCG cystitis included many agents, these treatment options had very limited outcomes. The existence of paraganglioma in the female genital tract described rarely
Source: International Journal of Surgery Case Reports - March 30, 2019 Category: Surgery Source Type: research

Botulinum toxin type A injection after failure of augmentation enterocystoplasty performed for neurogenic detrusor overactivity: preliminary results of a salvage strategy. The ENTEROTOX study
To evaluate the clinical efficacy, urodynamic effect and safety of Botulinum Toxin A (BTXA) injections after failure of augmentation enterocystoplasty (AE) performed for NDO. (Source: Urology)
Source: Urology - March 26, 2019 Category: Urology & Nephrology Authors: Floriane Michel, Carine Ciceron, Benjamin Bernuz, Romain Boissier, Sarah Gaillet, Alexia Even, Emmanuel Chartier-Kastler, Pierre Denys, Xavier Gam é, Alain Ruffion, Loïc Le Normand, Brigitte Perrouin-Verbe, Christian Saussine, Andrea Manunta, Véronique Source Type: research

Endoscopic Management of Postradiation Dysphagia in Head and Neck Cancer Patients: A Systematic Review.
CONCLUSIONS:: The lack of consistency across trials indicates insufficient evidence for guiding clinical practice. This systematic review suggests the need for greater standardization of outcomes and instruments. Future prospective evaluation should use validated patient-rated and clinician-rated assessment tools to optimally measure postoperative swallowing outcomes of head and neck cancer dysphagic patients following organ preservation therapy. PMID: 30895823 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - March 21, 2019 Category: ENT & OMF Authors: Abu-Ghanem S, Sung CK, Junlapan A, Kearney A, DiRenzo E, Dewan K, Damrose EJ Tags: Ann Otol Rhinol Laryngol Source Type: research

PrabotulinumtoxinA (Jeuveau) for Frown Lines
Date: May 20, 2019 Issue #:  1572Summary:  The FDA has approved prabotulinumtoxinA-xvfs (Jeuveau– Evolus) for temporary improvement in the appearance of moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity.Jeuveau is the fourth botulinum toxin product to be approved in the US for this indication (see Table 1). It has been available in South Korea asNabota since 2014. (Source: The Medical Letter)
Source: The Medical Letter - March 20, 2019 Category: Drugs & Pharmacology Authors: admin Tags: Botox Botulinum toxin Dysport Jeuveau Nuceiva Xeomin Source Type: research

Achalasia: treatment, current status and future advances.
LL Abstract Achalasia was first described in the 17th century and its treatment continues to be challenging. Palliative treatment involves disruption of the lower esophageal sphincter, which can be accomplished mechanically (balloon dilation or surgical myotomy) or chemically (Botox). True surgical treatment originated some 100 years ago and remained largely unchanged until the advent of thoracoscopic and then laparoscopic myotomy beginning in the 1980s. Because these procedures provided relatively definitive treatment and were well tolerated by patients, minimal invasive surgery assumed a primary role in the tre...
Source: The Korean Journal of Internal Medicine - March 15, 2019 Category: Internal Medicine Authors: Swanström LL Tags: Korean J Intern Med Source Type: research

Nummular Headache: 2 Cases With Good Beta Blocker Responses and a Narrative Review.
CONCLUSIONS: NH can be a disabling headache in more than half of identified patients and requires medical intervention. As with the previous treatment recommendations, gabapentin was the most commonly used prophylactic with a good response. Our cases suggested that β-adrenergic blockers could be a therapeutic option for NH patients with focal trophic changes within the areas. PMID: 30869172 [PubMed - as supplied by publisher] (Source: Headache)
Source: Headache - March 14, 2019 Category: Neurology Authors: Jiang L, Li M, Liu Q, Liu C, Zhou J Tags: Headache Source Type: research

The efficacy of botulinum toxin a lower limb injections in addition to physiotherapy approaches in children with cerebral palsy: A systematic review.
CONCLUSIONS: The use of BTX-A injections in addition to physiotherapy approaches seems to have positive effect on spasticity and ROM. However, the question of whether the treatment of BTX-A plus physiotherapy has a greater improvement on functional capacity, such as gross motor function or gait parameter than only physiotherapy treatments, was inconclusive. Further investigation by rigorous studies is required. PMID: 30856126 [PubMed - as supplied by publisher] (Source: NeuroRehabilitation)
Source: NeuroRehabilitation - March 13, 2019 Category: Rehabilitation Tags: NeuroRehabilitation Source Type: research

Pain and muscles properties modifications after botulinum toxin type A (BTX-A) and radial Extracorporeal Shock Wave (rESWT) combined treatment.
CONCLUSIONS: Radial Extracorporeal Shock Wave Therapy could be an effective physical treatment aimed at the reduction of upper and lower limbs spasticity and could lead to the improvement of trophic conditions of the spastic muscles in post-stroke. PMID: 30843498 [PubMed - as supplied by publisher] (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - March 8, 2019 Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research

The use of botulinum toxin type A to minimize scarring in cleft lip repair: A literature review.
Authors: Alhazmi B, Aldekhayel S PMID: 30812070 [PubMed - as supplied by publisher] (Source: Archives of Plastic Surgery)
Source: Archives of Plastic Surgery - March 1, 2019 Category: Cosmetic Surgery Tags: Arch Plast Surg Source Type: research

Debunking a Surgical Myth: Do Not Touch the Temporalis
Conclusions: The authors’ low reoperation rates for recurrent deformity, in combination with persistent temporalis overcorrection in 5.6% of patients, should dispel the myth that manipulation of the temporalis invariably results in atrophy. The muscle may be surgically manipulated, as long as plastic surgery principles are followed. (Source: Journal of Craniofacial Surgery)
Source: Journal of Craniofacial Surgery - March 1, 2019 Category: Surgery Tags: Original Articles Source Type: research

Treatment of Keloid Scars with Botulinum Toxin Type A versus Triamcinolone in an Athymic Nude Mouse Model
Background: Keloid scarring is a serious condition that mostly affects patients of African or Asian descent. Often disfiguring, this condition can have devastating psychosocial consequences. To date, no treatment modality has been proven ideal. The authors’ objectives were (1) to determine the efficacy of botulin toxin type A injection for the treatment of keloid scars compared to steroid injection and to control saline injection (this was achieved through a basic science animal model using athymic nude mice and implanted human keloid tissue); and (2) to analyze the histopathologic changes that occur in an organize...
Source: Plastic and Reconstructive Surgery - February 28, 2019 Category: Cosmetic Surgery Tags: Experimental Source Type: research

Discussion: Treatment of Keloid Scars with Botulinum Toxin Type A versus Triamcinolone in an Athymic Nude Mouse Model
No abstract available (Source: Plastic and Reconstructive Surgery)
Source: Plastic and Reconstructive Surgery - February 28, 2019 Category: Cosmetic Surgery Tags: Experimental Source Type: research

Effect of Perivascular Injection of Botulinum Toxin Type A versus Lidocaine in Survival of Random Pattern Flaps in a Rat Model
This study examines the role of botulinum toxin type A and lidocaine in augmentation of flap survival and decreasing the rate of necrosis in random pattern cutaneous flaps. Methods: In 45 male Sprague-Dawley rats, random pattern skin flaps with different width-to-length ratios were elevated. Botulinum toxin type A, lidocaine, or saline was administered to the base and whole length of the flap. Flap survival was evaluated on day 10 after surgery. The area of flap survival was determined grossly on the basis of its appearance, color, and texture. Results: The botulinum toxin type A group had a greater survival area (p ...
Source: Plastic and Reconstructive Surgery - February 28, 2019 Category: Cosmetic Surgery Tags: Experimental Source Type: research

Comparison between intra-articular Botulinum toxin type A, corticosteroid, and saline in knee osteoarthritis: a randomized controlled trial.
CONCLUSION:: IAI with TH had a higher effectiveness than that with TBA or SS in the short-term assessment (four weeks) for pain in movement, WOMAC, and US measurement of synovial hypertrophy. PMID: 30782000 [PubMed - as supplied by publisher] (Source: Clinical Rehabilitation)
Source: Clinical Rehabilitation - February 19, 2019 Category: Rehabilitation Authors: Mendes JG, Natour J, Nunes-Tamashiro JC, Toffolo SR, Rosenfeld A, Furtado RNV Tags: Clin Rehabil Source Type: research

Botox treatment in patients with chronic functional anorectal pain: experiences of a tertiary referral proctology clinic
ConclusionsChronic functional anorectal pain can be treated successfully with BTX-A in 47% of patients who fail conservative management. Repeated injections may be needed to ensure complete cure in a subgroup of patients. (Source: Techniques in Coloproctology)
Source: Techniques in Coloproctology - February 16, 2019 Category: Surgery Source Type: research

A new injective protocol for the treatment of frontal lines with botulinum toxin type A.
Authors: Melfa F, Rauso R PMID: 30734546 [PubMed - as supplied by publisher] (Source: Journal of Biological Regulators and Homeostatic Agents)
Source: Journal of Biological Regulators and Homeostatic Agents - February 10, 2019 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Subcutaneous botulinum toxin type A injections for provoked vestibulodynia: a randomized placebo-controlled trial and exploratory subanalysis
ConclusionsPVD symptoms after one subcutaneous injection of BT (50 or 100 units) did not significantly differ compared to placebo, yet all three study arms experienced a reduction in pain 3  months after a single injection. Exploratory analyses indicated that repeat high-dose BT injections may significantly reduce pain over 6 months.Trial registrationThis trial was registered with the Swiss Medical Agency (reference number: 2007DR2102) in 2007. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - February 1, 2019 Category: OBGYN Source Type: research

The Use of Botulinum Toxin Type A in the Healing of Thyroidectomy Wounds: A Randomized, Prospective, Placebo-Controlled Study
Conclusions: This study indicates that botulinum toxin type A administration immediately after surgical closure of a thyroid incision does not demonstrate a difference in scar outcomes compared with the control side. However, there was less scarring in subjects who had a severe scar history. This study found opposite results to a similarly designed study. Further study is required to determine the optimal use of botulinum toxin type A for wound healing. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, II. (Source: Plastic and Reconstructive Surgery)
Source: Plastic and Reconstructive Surgery - January 30, 2019 Category: Cosmetic Surgery Tags: Reconstructive: Head and Neck: Original Articles Source Type: research

Management of Chronic Migraine and Occipital Neuralgia in Post 9/11 Combat Veterans.
Conclusion: This study evaluated the effectiveness of using occipital blocks and Botox as dual therapy for reducing headache frequency for post 9/11 combat veterans with CM, occipital neuralgia, and a history of TBI or neck trauma. Results revealed a statistically significant reduction in the number of headache days per month after the dual therapy. There were multiple limitations to the study to include a small sample size, lack of a control group, self-reported headaches for only 1 month pre-and post-treatment, and no control for other interventions or events which may have influenced the outcome. There is a strong need ...
Source: Military Medicine - January 30, 2019 Category: International Medicine & Public Health Tags: Mil Med Source Type: research

Botulinum Toxin Type A for the Treatment of Lower Limb Spasticity after Stroke
AbstractPost-stroke lower limb spasticity impairs balance and gait leading to reduced walking speed, often increasing wheelchair use and caregiver burden. Several studies have shown that appropriate treatments for lower limb spasticity after stroke include injections of botulinum toxin type A (BoNT-A), phenol or alcohol, surgical correction and a rehabilitation program. In the present article, we review the safety and effectiveness of BoNT-A for the treatment of lower limb spasticity after stroke, with a focus on higher doses of BoNT-A. The cumulative body of evidence coming from the randomized clinical trials and open-lab...
Source: Drugs - January 8, 2019 Category: Drugs & Pharmacology Source Type: research

Incisional hernia repair with plication and utilization of Botox injections: First case report from Saudi Arabia for a 19 ‐year‐old female
This article reports on the use of Botox preoperatively for the treatment of a complex ventral hernia which would have typically been treated with component separation technique. The case demonstrates that using the recently developed technique can aid in performing a tension ‐free hernia repair with potentially lower complication and recurrence rates. Key Clinical MessageThis article reports on the use of Botox preoperatively for the treatment of a complex ventral hernia which would have typically been treated with component separation technique. The case demonstrates that using the recently developed technique can aid ...
Source: Clinical Case Reports - January 8, 2019 Category: General Medicine Authors: Talal Hijji, Abdullah AlShammari, Alanoud AlHammad, Ghadah AlKhalefah, Fuad Hashem, Salha Almomen, Mohammad Aburahmah Tags: CASE REPORT Source Type: research

Management of Hirschsprung disease in Australia and New Zealand: a survey of the Australian and New Zealand Association of Paediatric Surgeons (ANZAPS)
AbstractPurposeTo define the practice of management for Hirschsprung disease (HD) in Australia and New Zealand.MethodsOnline survey of Australian and New Zealand Association of Paediatric Surgeons (ANZAPS) members.Results56/80 (70%) members from 17 centres responded.Diagnosis100% perform suction rectal biopsies; 40% perform a contrast enema.Histopathological stainingH&E (94%), ACHE (70%) and calretinin (75%).SurgeryPrimary pull-through (PT) is performed by 88% (100% by
Source: Pediatric Surgery International - January 3, 2019 Category: Surgery Source Type: research

Botox or No-Tox?
(Source: Obesity Surgery)
Source: Obesity Surgery - January 2, 2019 Category: Surgery Source Type: research

A case study investigating the efficacy of two treatments, botox and SaeboFlex in reduced hand function due to flexor spasticity
Purpose: Dynamic hand splints such as Saeboflex are a promising intervention for aiding functional use of a person's hand following a stroke. If spasticity is present it can be a major limiting factor in using a Saeboflex. The purpose of this case study is to report the use of a combination of Botulinum Toxin Type A (BtxA) to reduce spasticity, prior to initiating a repetitive training rehabilitation programme with a Saeboflex. (Source: Physiotherapy)
Source: Physiotherapy - January 1, 2019 Category: Physiotherapy Authors: J.A. Benson Tags: P087 Source Type: research

Successful treatment of red ear syndrome with botulinum toxin type A
Maria Castellanos-Gonzalez, Fernando De Manueles, María García Martos, Maria Agustina Segurado RodríguezIndian Journal of Dermatology, Venereology, and Leprology 2019 85(1):107-108 (Source: Indian Journal of Dermatology, Venereology and Leprology)
Source: Indian Journal of Dermatology, Venereology and Leprology - December 30, 2018 Category: Dermatology Authors: Maria Castellanos-Gonzalez Fernando De Manueles Mar & #237;a Garc & #237;a Martos Maria Agustina Segurado Rodr & #237;guez Source Type: research

The Masseter Muscle and Its Role in Facial Contouring, Aging, and Quality of Life: A Literature Review
Conclusions: Botulinum toxin type A is a safe and effective treatment of masseter hypertrophy. The treatment results in improvement of functionality and cosmesis, and restoration of facial harmony. (Source: Plastic and Reconstructive Surgery)
Source: Plastic and Reconstructive Surgery - December 28, 2018 Category: Cosmetic Surgery Tags: Cosmetic: Original Articles Source Type: research

Impact of Botulinum Toxin Type A Treatment of the Glabella and Crow's Feet on Static Forehead Rhytides
No abstract available (Source: Dermatologic Surgery)
Source: Dermatologic Surgery - December 25, 2018 Category: Dermatology Tags: Letters and Communications Source Type: research

Utility of ultrasound-guided injection of botulinum toxin type A for muscle imbalance in children with obstetric brachial plexus palsy: description of the procedure and action protocol
In this study, we explore the effectiveness of ultrasound-guided injection of botulinum toxin A (BoNT-A) and describe the procedure.Patients and methodsWe designed a prospective, descriptive study including patients with moderate to severe OBPP who were treated between January 2010 and December 2014. We gathered demographic data, type of OBPP, and progression. Treatment effectiveness was assessed with the Active Movement Scale (AMS), the Mallet classification, and video recordings.ResultsWe gathered a total of 14 133 newborns, 15 of whom had OBPP (1.6 per 1000 live births). Forty percent of the cases had severe OBPP (...
Source: Neurologia - December 19, 2018 Category: Neurology Source Type: research

Botulinum Toxin-Treatment of Localized Provoked Vulvodynia refractory to conventional treatment
Publication date: Available online 15 December 2018Source: European Journal of Obstetrics & Gynecology and Reproductive BiologyAuthor(s): Thomas Hedebo Hansen, Rikke Guldberg, Mette MeinertAbstractIntroductionWe wanted to evaluate the efficacy of botulinum toxin type A (botulinum toxin) treatment on vulvodynia refractory to conventional treatment.Material and methodsA follow-up study on botulinum toxin treatment was conducted at Aarhus University Hospital (n = 109). Seventy-nine completed the follow-up. The women included had localized provoked vulvodynia, refractory to first line treatment and were treat...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - December 16, 2018 Category: OBGYN Source Type: research