Botulinum toxin type a improves pain in numb chin syndrome
We describe a case of bilateral numb chin syndrome, secondary to Burkitt lymphoma, associated with refractory and persistent burning neuropathic pain, effectively treated twelve times with subcutaneous Botulinum toxin type A (BoNT/A) injections. The procedure was well tolerated, but the patient reported incomplete mouth closure of minimal entity. BoNT/A could be a safe and effective therapy for neuropathic pain associated with numb chin syndrome.PMID:38159684 | DOI:10.1016/j.toxicon.2023.107565 (Source: Toxicon)
Source: Toxicon - December 30, 2023 Category: Toxicology Authors: Yan Tereshko Bruno Hector Ercole Lettieri Christian Enrico Belgrado Simone Dal Bello Merlino Giovanni Gian Luigi Gigli Mariarosaria Valente Source Type: research
Evaluation of biochemical changes and treatment efficacy in patients with bruxism following botulinum toxin or splint therapy: a randomized clinical trial
ConclusionsStress and inflammatory biomarkers were found to be associated with bruxism. Cortisol levels decreased in people with bruxism after treatment with both occlusal splint and botox.Clinical relevanceBoth splint and botox treatments were effective for bruxism by reducing the stress levels. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - December 28, 2023 Category: Dentistry Source Type: research
Robotic gait training and botulinum toxin injection improve gait in the chronic post-stroke phase: A randomized controlled trial
CONCLUSION: Two weeks of robotic gait training performed 2 weeks after BTx-A injections improved walking performance more than conventional physiotherapy. Large-scale studies are now required on the timing of robotic rehabilitation after BTx-A injection.PMID:38118342 | DOI:10.1016/j.rehab.2023.101785 (Source: Health Physics)
Source: Health Physics - December 20, 2023 Category: Physics Authors: Ma ëva Cotinat Mathilde Celerier Clelia Arquilli ère Margot Flipo Nicolas Prieur-Blanc Jean-Michel Viton Laurent Bensoussan Source Type: research
Botulinum toxin type a antinociceptive activity in trigeminal regions involves central transcytosis
CONCLUSION: Herein, we demonstrate that antinociceptive action of pericranially administered BoNT-A involves transsynaptic transport to second order synapses and contralateral trigeminal nociceptive nuclei. These results reveal more complex central toxin activity, necessary to explain its clinical effectiveness in the trigeminal region-related pain states.PMID:38123005 | DOI:10.1016/j.ejphar.2023.176279 (Source: European Journal of Pharmacology)
Source: European Journal of Pharmacology - December 20, 2023 Category: Drugs & Pharmacology Authors: Dalia Nemani ć Matej Mustapi ć Ivica Matak Lidija Bach-Rojecky Source Type: research
Robotic gait training and botulinum toxin injection improve gait in the chronic post-stroke phase: A randomized controlled trial
CONCLUSION: Two weeks of robotic gait training performed 2 weeks after BTx-A injections improved walking performance more than conventional physiotherapy. Large-scale studies are now required on the timing of robotic rehabilitation after BTx-A injection.PMID:38118342 | DOI:10.1016/j.rehab.2023.101785 (Source: Health Physics)
Source: Health Physics - December 20, 2023 Category: Physics Authors: Ma ëva Cotinat Mathilde Celerier Clelia Arquilli ère Margot Flipo Nicolas Prieur-Blanc Jean-Michel Viton Laurent Bensoussan Source Type: research
Botulinum toxin type a antinociceptive activity in trigeminal regions involves central transcytosis
CONCLUSION: Herein, we demonstrate that antinociceptive action of pericranially administered BoNT-A involves transsynaptic transport to second order synapses and contralateral trigeminal nociceptive nuclei. These results reveal more complex central toxin activity, necessary to explain its clinical effectiveness in the trigeminal region-related pain states.PMID:38123005 | DOI:10.1016/j.ejphar.2023.176279 (Source: European Journal of Pharmacology)
Source: European Journal of Pharmacology - December 20, 2023 Category: Drugs & Pharmacology Authors: Dalia Nemani ć Matej Mustapi ć Ivica Matak Lidija Bach-Rojecky Source Type: research
The Telltale Botox: Botulinum Toxin Injection by an Expert Hand as an Intracranial Aneurysm Detector
We present a case of a 48-year-old patient who, following botulinum toxin type A (Botox) injection for treatment of forehead wrinkles, returned to our attention 12 days later for a discrete, newly onset right eyelid ptosis. This ptosis was a telltale sign of the presence of an intracranial aneurysm closely related with the oculomotor nerve. The lack of compensatory action by the frontalis muscle in maintaining the eyelid in position allowed us to highlight the extrinsic compression deficit of the oculomotor nerve. Subsequently, the patient underwent endovascular treatment of the aneurysm, leading to complete resolution of ...
Source: Hand Surgery - December 14, 2023 Category: Surgery Authors: Giorgio Caddia Giulio J Jaber Francesca Granata Karol Galletta Antonio Pitrone Paolino La Spina Ferdinando Stagno d'Alcontres Francesco Stagno d'Alcontres Source Type: research
The Telltale Botox: Botulinum Toxin Injection by an Expert Hand as an Intracranial Aneurysm Detector
We present a case of a 48-year-old patient who, following botulinum toxin type A (Botox) injection for treatment of forehead wrinkles, returned to our attention 12 days later for a discrete, newly onset right eyelid ptosis. This ptosis was a telltale sign of the presence of an intracranial aneurysm closely related with the oculomotor nerve. The lack of compensatory action by the frontalis muscle in maintaining the eyelid in position allowed us to highlight the extrinsic compression deficit of the oculomotor nerve. Subsequently, the patient underwent endovascular treatment of the aneurysm, leading to complete resolution of ...
Source: Hand Surgery - December 14, 2023 Category: Surgery Authors: Giorgio Caddia Giulio J Jaber Francesca Granata Karol Galletta Antonio Pitrone Paolino La Spina Ferdinando Stagno d'Alcontres Francesco Stagno d'Alcontres Source Type: research
An analysis of the efficacy of botulinum neurotoxin type a in treating cervical dystonia
CONCLUSION: BoNT is an effective and safe method for treating CD. The maximum remission rates of patients after their first injections are influenced by the duration of their disease. Thus, treatment using BoNT injections must be administered as soon as possible.PMID:38073352 | DOI:10.3233/THC-231182 (Source: Technology and Health Care)
Source: Technology and Health Care - December 11, 2023 Category: Medical Devices Authors: Xuan Zhou Zhen-Fei Li Xuan-Zhu Guo Qiao Wei Ya-Nan Niu Meng Li Jia-Ning Xia Li-Ping Chen Source Type: research
An analysis of the efficacy of botulinum neurotoxin type a in treating cervical dystonia
CONCLUSION: BoNT is an effective and safe method for treating CD. The maximum remission rates of patients after their first injections are influenced by the duration of their disease. Thus, treatment using BoNT injections must be administered as soon as possible.PMID:38073352 | DOI:10.3233/THC-231182 (Source: Technology and Health Care)
Source: Technology and Health Care - December 11, 2023 Category: Medical Devices Authors: Xuan Zhou Zhen-Fei Li Xuan-Zhu Guo Qiao Wei Ya-Nan Niu Meng Li Jia-Ning Xia Li-Ping Chen Source Type: research
An analysis of the efficacy of botulinum neurotoxin type a in treating cervical dystonia
CONCLUSION: BoNT is an effective and safe method for treating CD. The maximum remission rates of patients after their first injections are influenced by the duration of their disease. Thus, treatment using BoNT injections must be administered as soon as possible.PMID:38073352 | DOI:10.3233/THC-231182 (Source: Technology and Health Care)
Source: Technology and Health Care - December 11, 2023 Category: Medical Devices Authors: Xuan Zhou Zhen-Fei Li Xuan-Zhu Guo Qiao Wei Ya-Nan Niu Meng Li Jia-Ning Xia Li-Ping Chen Source Type: research
An analysis of the efficacy of botulinum neurotoxin type a in treating cervical dystonia
CONCLUSION: BoNT is an effective and safe method for treating CD. The maximum remission rates of patients after their first injections are influenced by the duration of their disease. Thus, treatment using BoNT injections must be administered as soon as possible.PMID:38073352 | DOI:10.3233/THC-231182 (Source: Technology and Health Care)
Source: Technology and Health Care - December 11, 2023 Category: Medical Devices Authors: Xuan Zhou Zhen-Fei Li Xuan-Zhu Guo Qiao Wei Ya-Nan Niu Meng Li Jia-Ning Xia Li-Ping Chen Source Type: research
An analysis of the efficacy of botulinum neurotoxin type a in treating cervical dystonia
CONCLUSION: BoNT is an effective and safe method for treating CD. The maximum remission rates of patients after their first injections are influenced by the duration of their disease. Thus, treatment using BoNT injections must be administered as soon as possible.PMID:38073352 | DOI:10.3233/THC-231182 (Source: Technology and Health Care)
Source: Technology and Health Care - December 11, 2023 Category: Medical Devices Authors: Xuan Zhou Zhen-Fei Li Xuan-Zhu Guo Qiao Wei Ya-Nan Niu Meng Li Jia-Ning Xia Li-Ping Chen Source Type: research
An analysis of the efficacy of botulinum neurotoxin type a in treating cervical dystonia
CONCLUSION: BoNT is an effective and safe method for treating CD. The maximum remission rates of patients after their first injections are influenced by the duration of their disease. Thus, treatment using BoNT injections must be administered as soon as possible.PMID:38073352 | DOI:10.3233/THC-231182 (Source: Technology and Health Care)
Source: Technology and Health Care - December 11, 2023 Category: Medical Devices Authors: Xuan Zhou Zhen-Fei Li Xuan-Zhu Guo Qiao Wei Ya-Nan Niu Meng Li Jia-Ning Xia Li-Ping Chen Source Type: research
Professor Alan B. Scott (1932-2021): "The inventor of Botox"
Rev Neurol (Paris). 2023 Dec 5:S0035-3787(23)01142-6. doi: 10.1016/j.neurol.2023.10.012. Online ahead of print.NO ABSTRACTPMID:38057183 | DOI:10.1016/j.neurol.2023.10.012 (Source: Revue Neurologique)
Source: Revue Neurologique - December 6, 2023 Category: Neurology Authors: M-H Marion Source Type: research
