Role of direct antiglobulin test in anemia under evaluation: Its prevalence, laboratory workup, and significance in further patient management-a study from eastern India
CONCLUSION: DAT played a significant role in the diagnosis as well as evaluation of AIHA.PMID:38563700 | DOI:10.4103/ijpm.ijpm_724_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Sumita Pandey Chikam Maity Sambit K Samanta Arunansu Talukdar Arijit Das Sandip Paul Prasun Bhattacharya Pushpak Das Source Type: research
Secondary syphilis presenting with alopecia and leukoderma in a stable HIV-positive patient in a resource-limited setting: a case report
CONCLUSION: This case demonstrates the importance of a high index of clinical suspicion and testing for syphilis in patients presenting with atypical clinical features of secondary syphilis, such as hair loss and hypopigmentation. It also highlights the challenges in diagnosing and clinically managing syphilis in a resource-limited setting.PMID:38561779 | DOI:10.1186/s12981-024-00603-w (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 2, 2024 Category: Infectious Diseases Authors: Sukoluhle Khumalo Yves Mafulu Victor Williams Normusa Musarapasi Samson Haumba Nkululeko Dube Source Type: research
Role of direct antiglobulin test in anemia under evaluation: Its prevalence, laboratory workup, and significance in further patient management-a study from eastern India
CONCLUSION: DAT played a significant role in the diagnosis as well as evaluation of AIHA.PMID:38563700 | DOI:10.4103/ijpm.ijpm_724_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - April 2, 2024 Category: Pathology Authors: Sumita Pandey Chikam Maity Sambit K Samanta Arunansu Talukdar Arijit Das Sandip Paul Prasun Bhattacharya Pushpak Das Source Type: research
Secondary syphilis presenting with alopecia and leukoderma in a stable HIV-positive patient in a resource-limited setting: a case report
CONCLUSION: This case demonstrates the importance of a high index of clinical suspicion and testing for syphilis in patients presenting with atypical clinical features of secondary syphilis, such as hair loss and hypopigmentation. It also highlights the challenges in diagnosing and clinically managing syphilis in a resource-limited setting.PMID:38561779 | PMC:PMC10986119 | DOI:10.1186/s12981-024-00603-w (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - April 2, 2024 Category: Infectious Diseases Authors: Sukoluhle Khumalo Yves Mafulu Victor Williams Normusa Musarapasi Samson Haumba Nkululeko Dube Source Type: research
Trends in immunological markers of transfusion transmissible infections among blood donors in Mamfe District Hospital, Southwest Cameroon
Blood transfusion is associated with exposure to blood Transfusion Transmissible Infection (TTIs). The threat posed by the blood-borne pathogens is disproportionately distributed in different healthcare facili... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 2, 2024 Category: Infectious Diseases Authors: Sen Claudine Henriette Ngomtcho, Olive Njike Ngo Biyong, Timothy Amos Ekwere, Jonas Merlin Wandji Takemegni, Henrietta Mbah, Sandra Maella Makamdoum Bogne, Omer Aurelle Nkengkanna and Henri Lucien Fouamno Kamga Tags: Research Source Type: research
Ex-Vivo TCR αβ and CD19 Depleted Haploidentical Stem Cell Transplantation with CD45RO Memory T Cell Addback for CARD11 Deficiency
(Source: Indian Journal of Hematology and Blood Transfusion)
Source: Indian Journal of Hematology and Blood Transfusion - April 2, 2024 Category: Hematology Source Type: research
Anemia in patients receiving anticancer treatments: focus on novel therapeutic approaches
Anemia is common in cancer patients and impacts on quality of life and prognosis. It is typically multifactorial, often involving different pathophysiological mechanisms, making treatment a difficult task. In patients undergoing active anticancer treatments like chemotherapy, decreased red blood cell (RBC) production due to myelosuppression generally predominates, but absolute or functional iron deficiency frequently coexists. Current treatments for chemotherapy-related anemia include blood transfusions, erythropoiesis-stimulating agents, and iron supplementation. Each option has limitations, and there is an urgent need fo...
Source: Frontiers in Oncology - April 2, 2024 Category: Cancer & Oncology Source Type: research
Patients with red cell antibodies: registries improve patient care by increasing patient safety, reducing costs, and enabling health information exchange
Blood Transfus. 2024 Mar 15. doi: 10.2450/BloodTransfus.753. Online ahead of print.NO ABSTRACTPMID:38557326 | DOI:10.2450/BloodTransfus.753 (Source: Blood Transfusion)
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Willy Albert Flegel Source Type: research
Types of plasma exchange solution in the new scenario of thrombotic thrombocytopenic purpura treatment
Blood Transfus. 2024 Mar 4. doi: 10.2450/BloodTransfus.744. Online ahead of print.NO ABSTRACTPMID:38557325 | DOI:10.2450/BloodTransfus.744 (Source: Blood Transfusion)
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Nadia Garc ía Muñoz Sandra Ortega S ánchez Joan R Grifols Source Type: research
Development and evaluation of trigger tools to identify pediatric blood management errors
DISCUSSION: It is feasible to automatically detect pediatric PBM errors using existing data captured in the EHR that enable active surveillance systems. Over-transfusions may be one of the most frequent causes of harm in the pediatric environment.PMID:38557324 | DOI:10.2450/BloodTransfus.606 (Source: Blood Transfusion)
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Swaminathan Kandaswamy Cassandra D Josephson Margo R Rollins Jennifer Jones Patricia Zerra Ruchika Goel Jennifer Andrews Jeanne E Hendrickson Lani Lieberman Evan W Orenstein Source Type: research
Genomic characterisation of clinically significant blood group variants in Aboriginal Australians
In this study, we applied next-generation sequencing and analysis to 245 samples obtained from Aboriginal Australians from South-East Queensland, to predict antigen phenotypes for 36 blood group systems.RESULTS: We report potential weak antigens in blood group systems RH, FY and JR that have potential clinical implications in transfusion and pregnancy settings. These include partial DIII type 4, weak D type 33, and Del RHD (IVS2-2delA). The rare Rh phenotypes D+ C+ E+ c- e+ and D+ C+ E+ c+ e- were also detected.DISCUSSION: The comprehensive analyses of blood group genetic variant profiles identified in this study will prov...
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Sudhir Jadhao Candice Davison Eileen Roulis Simon Lee Tamika Campbell Reece Griffin Maree Toombs Alex Brown Maree Perry Bushra Nasir David O Irving Catherine A Hyland Robert L Flower Shivashankar H Nagaraj Source Type: research
Platelet rich plasma for facial rejuvenation: an overview of systematic reviews
This article aims to review the literature and critically appraise the available evidence regarding the efficacy and safety of PRP for facial rejuvenation.MATERIAL AND METHODS: An overview of systematic reviews (SRs) of PRP use for facial rejuvenation. The methodological quality of the SRs was assessed using the AMSTAR-2 checklist; quality of the evidence from the trials included in each SR was appraised following the GRADE approach.RESULTS: Thirteen SRs published between 2015 and 2023, reporting data from 114 overlapping reports, based on 28 individual primary studies (18 uncontrolled reports), were included in this umbre...
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Mario Cruciani Francesca Masiello Ilaria Pati Simonetta Pupella Vincenzo De Angelis Source Type: research
A survey on the implementation of Patient Blood Management programs in Italy
DISCUSSION: The first national survey on the level of PBM implementation in Italy shows widespread adoption of diagnostic-therapeutic care pathways aimed at the diagnosis and treatment of anemia in the perioperative setting.PMID:38557321 | DOI:10.2450/BloodTransfus.724 (Source: Blood Transfusion)
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Vanessa Agostini Francesca Masiello Stefania Vaglio Eva Veropalumbo Ursula La Rocca Simonetta Pupella Vincenzo De Angelis Source Type: research
Identification of the novel c.300C & gt;G variation on the ABO*A1.02 allele associated with an A weak B phenotype
Blood Transfus. 2024 Feb 28. doi: 10.2450/BloodTransfus.642. Online ahead of print.NO ABSTRACTPMID:38557320 | DOI:10.2450/BloodTransfus.642 (Source: Blood Transfusion)
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Yuqing Shen Junshun Gong Yuyu Zhang Naizhu Su Lou Can Jiaming Li Dong Xiang Xiaohong Cai Hang Lei Source Type: research
Why might cord blood be a better source of platelets for transfusion to neonates?
Blood Transfus. 2024 Mar 27. doi: 10.2450/BloodTransfus.566. Online ahead of print.ABSTRACTThrombocytopenia (defined as a platelet count <150×109/L) is a common condition in preterm neonates and may occur in 18-35% of all infants admitted to the Neonatal Intensive Care Unit (NICU). Neonatal platelet functionality in terms of reactivity is often described as reduced compared to adults, even in healthy, term neonates. However, this platelet "hyporeactivity" does not correspond to a global functional impairment of the normal delicately balanced neonatal hemostatic system. The extent to which neonatal thrombocytopenia and ...
Source: Blood Transfusion - April 1, 2024 Category: Hematology Authors: Valeria Cortesi Giacomo Cavallaro Genny Raffaeli Stefano Ghirardello Fabio Mosca Thomas R L Klei Suzanne Fustolo-Gunnink Simon Stanworth Helen V New Em öke Deschmann Enrico Lopriore Source Type: research
