Web-based cognitive rehabilitation intervention for cancer-related cognitive impairment following chemotherapy for aggressive lymphoma: protocol for a randomised pilot trial
Introduction Cancer-related cognitive impairment is common among people diagnosed with and treated for cancer. This can be a distressing and disabling side effect for impacted individuals. Interventions to mitigate cognitive dysfunction are available, but, to date, most have been trialled in samples that are largely or exclusively composed of people with solid tumours. Intervention strategies to support cognitive functioning are needed, but there is a paucity of research in this area. The main aim of this study is to test the feasibility and acceptability of methods and procedures intended for use in a definitive trial of ...
Source: BMJ Open - April 22, 2024 Category: General Medicine Authors: Gates, P., Green, H. J., Gough, K., Dhillon, H., Vardy, J. L., Dickinson, M., Guarnera, J., Krishnasamy, M., Livingston, P. M., White, V., Ugalde, A., Caeyenberghs, K. Tags: Open access, Haematology (incl blood transfusion) Source Type: research

Comparison of blood transfusion strategies for acute coronary syndrome patients with anemia: A meta-analysis of five randomized controlled trials
J Cardiol. 2024 Apr 19:S0914-5087(24)00068-6. doi: 10.1016/j.jjcc.2024.04.005. Online ahead of print.NO ABSTRACTPMID:38642888 | DOI:10.1016/j.jjcc.2024.04.005 (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 20, 2024 Category: Cardiology Authors: Yuko Kiyohara Alexandros Briasoulis Toshiki Kuno Source Type: research

Comparison of blood transfusion strategies for acute coronary syndrome patients with Anemia: A meta-analysis of five randomized controlled trials
J Cardiol. 2024 Apr 18:S0914-5087(24)00068-6. doi: 10.1016/j.jjcc.2024.04.005. Online ahead of print.NO ABSTRACTPMID:38642888 | DOI:10.1016/j.jjcc.2024.04.005 (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 20, 2024 Category: Cardiology Authors: Yuko Kiyohara Alexandros Briasoulis Toshiki Kuno Source Type: research

Comparison of blood transfusion strategies for acute coronary syndrome patients with Anemia: A meta-analysis of five randomized controlled trials
J Cardiol. 2024 Apr 18:S0914-5087(24)00068-6. doi: 10.1016/j.jjcc.2024.04.005. Online ahead of print.NO ABSTRACTPMID:38642888 | DOI:10.1016/j.jjcc.2024.04.005 (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 20, 2024 Category: Cardiology Authors: Yuko Kiyohara Alexandros Briasoulis Toshiki Kuno Source Type: research

Comparison of blood transfusion strategies for acute coronary syndrome patients with Anemia: A meta-analysis of five randomized controlled trials
J Cardiol. 2024 Apr 18:S0914-5087(24)00068-6. doi: 10.1016/j.jjcc.2024.04.005. Online ahead of print.NO ABSTRACTPMID:38642888 | DOI:10.1016/j.jjcc.2024.04.005 (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 20, 2024 Category: Cardiology Authors: Yuko Kiyohara Alexandros Briasoulis Toshiki Kuno Source Type: research

Comparison of blood transfusion strategies for acute coronary syndrome patients with Anemia: A meta-analysis of five randomized controlled trials
J Cardiol. 2024 Apr 18:S0914-5087(24)00068-6. doi: 10.1016/j.jjcc.2024.04.005. Online ahead of print.NO ABSTRACTPMID:38642888 | DOI:10.1016/j.jjcc.2024.04.005 (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 20, 2024 Category: Cardiology Authors: Yuko Kiyohara Alexandros Briasoulis Toshiki Kuno Source Type: research

Diffuse Large B Cell Lymphoma (DLBCL) Presenting Clinically as a Large Ulceroproliferative Mass
(Source: Indian Journal of Hematology and Blood Transfusion)
Source: Indian Journal of Hematology and Blood Transfusion - April 20, 2024 Category: Hematology Source Type: research

Association of Secretor And Nonsecretor Status with Lewis Phenotyping Among Blood Donors: A Prospective Observational Study from Tertiary Care Hospital
AbstractABO (ABH) antigen expression on red cell antigens and secretion of ABH substances in body fluids are governed by different genes. The presence or absence of the Secretor gene is the basis of secretor status positivity and negativity, respectively. Determination of the secretor status has an essential role in the medical field. It was a prospective observational study to determine the association of secretor and nonsecretor status with Lewis phenotyping among voluntary blood donors. It was conducted from Jan 2020 to December 2021 at the Department of Transfusion Medicine in a tertiary care hospital in South India. A...
Source: Indian Journal of Hematology and Blood Transfusion - April 20, 2024 Category: Hematology Source Type: research

Are Healthcare Professionals Adequately Trained for Safe Blood Transfusions? Targeted Training to Bridge Knowledge Gaps
ConclusionThis study demonstrates that the evaluation of knowledge should be carried out on a continuous manner in order to detect gaps in the professional sector and to ensure the effectiveness of training through well-targeted educational programs. (Source: Indian Journal of Hematology and Blood Transfusion)
Source: Indian Journal of Hematology and Blood Transfusion - April 20, 2024 Category: Hematology Source Type: research

A Case Report of Therapeutic Plasma Exchange in Hypertriglyceridemia-Induced Pancreatitis
AbstractTo support the evidence of plasma exchange ’s ability to rapidly lower serum TG levels and provide upcoming research opportunities for evaluating the long-term effects of this treatment, we present the case of a 35-year-old female who was admitted for Hypertriglyceridemia-induced Pancreatitis (HTGP). She underwent Therapeutic Plasma Excha nge (TPE) using Spectra Optia Apheresis System on an emergency basis. The patient had a remarkable reduction of serum Triglycerides (TG) from 3953 to 291 mg/dl, which was life saving. On subsequent follow-up the serum TG levels remained constant post-TPE with conservative trea...
Source: Indian Journal of Hematology and Blood Transfusion - April 20, 2024 Category: Hematology Source Type: research

Clinical Profile, Treatment and Outcome of Thrombotic Thrombocytopenia Purpura (TTP) in Rituximab Era- an Experience from Tertiary Care Centre from North India
AbstractThrombotic thrombocytopenic purpura (TTP) is a microangiopathic hemolytic anemia (MAHA) resulting from severe deficiency of ADAMTS13. TTP is an acute medical emergency which requires early treatment with therapeutic plasma exchange. With the early use of Rituximab along with PLEX, early response is achieved and relapse rate has gone down. There is lack of published data from India regarding treatment and outcome of TTP. We retrospectively analyzed our data of 21 patients of TTP including 4 patients who had TA-TMA. TTP patients were treated with TPE, pulse methylprednisolone and rituximab. After a median follow up o...
Source: Indian Journal of Hematology and Blood Transfusion - April 20, 2024 Category: Hematology Source Type: research

Platelet-Rich Plasma Sequestration in Cardiac Surgery in a Jehovah's Witness
Jehovah's Witnesses (JW) refuse allogeneic blood transfusions due to their religious beliefs. This situation poses significant challenges in the context of cardiac surgery, given that bleeding-related complications may arise during and after the procedure.1 Platelet-rich plasma (PRP) sequestration in cardiac surgery has been previously described.2-4 The new-generation autotransfusion device XTRA (LivaNova, UK) processes fresh donor blood using the device's built-in ‘PLT sequestration program’. According to Seyfried, platelet recovery in the PRP ranged from 39%-64%. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 19, 2024 Category: Anesthesiology Authors: Tabesh Azami, Bastiaan M Gerritse, Rene Daane, Thierry V Scohy Tags: Case Report Source Type: research

Efficacy and Safety of Weekly Bortezomib-dexamethasone as the Third-Line Therapy for Warm Autoimmune Hemolytic Anemia: a Case Series of 5 Patients
AbstractBackgroundWarm autoimmune hemolytic anaemia (wAIHA) is a chronic condition. Despite the high initial responses seen with the first two treatment lines (corticosteroids and rituximab), relapses are frequent. Anecdotal data suggests the efficacy of bortezomib in relapsed/refractory (RR) wAIHA. This case series aimed to evaluate bortezomib as a third-line therapy in wAIHA in terms of efficacy, safety, and prospects of achieving treatment-free remission (TFR). Five adult patients  ≥ 18 years of age with RR wAIHA after corticosteroids and rituximab were included over 1.5 years. Patients were treated uniformly wi...
Source: Indian Journal of Hematology and Blood Transfusion - April 19, 2024 Category: Hematology Source Type: research

Equity in blood transfusion precision services
Blood collection agencies are integrating precision medicine techniques to improve and individualise blood donor and recipient outcomes. These organisations have a role to play in ensuring equitable applicatio... (Source: International Journal for Equity in Health)
Source: International Journal for Equity in Health - April 18, 2024 Category: International Medicine & Public Health Authors: Georgina Jacko, Rachel Thorpe and James Daly Tags: Comment Source Type: research