Influence of caffeine intake on intravenous adenosine-induced fractional flow reserve.
This study evaluated whether caffeine abstention is required before fractional flow reserve (FFR) measurement by intravenous adenosine triphosphate (ATP) administration in Japanese patients. METHODS: This study was a subanalysis of a previously published study and a total of 208 intermediate lesions that underwent FFR measurements were enrolled for this analysis. Hyperemia was induced by continuous intravenous ATP infusion at 150 μg/kg/min (IVATP150) and 210 μg/kg/min (IVATP210), and by intracoronary administration of nicorandil 2 mg (ICNIC2mg) as a reference standard. RESULTS: The degr...
Source: Journal of Cardiology - June 9, 2020 Category: Cardiology Authors: Kasumi I, Fujii K, Satoru O, Shin T, Katsuyuki H, Hiroto T, Rui I, Shingo Y, Sho N, Wataru Y, Hirofumi K, Yusuke T, Mikio K, Yuji S, Yorihiko H Tags: J Cardiol Source Type: research

Clinical characteristics of challenging catheter ablation procedures in patients with WPW syndrome: A 10 year single-center experience.
lò L Abstract BACKGROUND: Catheter ablation is the established treatment for patients with symptomatic Wolff-Parkinson-White syndrome (WPW). However, some patients undergo a challenging ablation or have recurrences during the early post-ablation phase. The aim of this study was to evaluate the clinical factors associated with an unsuccessful ablation outcome or repeated sessions. METHODS: Four hundred seventy-five symptomatic consecutive WPW patients (38.2±16.2 years old, 61% men, 69% with pre-excitation) who underwent an accessory pathway (AP) ablation from August 2005 to December 2015 were enr...
Source: Journal of Cardiology - June 9, 2020 Category: Cardiology Authors: Fujino T, De Ruvo E, Grieco D, Scará A, Borrelli A, De Luca L, Panuccio M, Fagagnini A, Bruni G, Sciarra L, Calò L Tags: J Cardiol Source Type: research

Impact of peripheral artery disease on prognosis after myocardial infarction: The J-MINUET study.
u N, Kozuma K, Uemura S, Tobaru T, Saku K, Oshima S, Nishimura K, Miyamoto Y, Ogawa H, Ishihara M, J-MINUET investigators Abstract BACKGROUND: Patients with peripheral artery disease (PAD) are at high risk of cardiovascular events, including myocardial infarction (MI), stroke, and cardiovascular death. However, the impact of PAD on prognosis in Japanese patients with acute MI remains unclear. METHODS: The Japanese registry of acute Myocardial INfarction diagnosed by Universal dEfiniTion (J-MINUET) is a prospective multicenter registry that registered 3283 patients with acute MI. Among them, 2970 patients with...
Source: Journal of Cardiology - June 9, 2020 Category: Cardiology Authors: Akahori H, Masuyama T, Imanaka T, Nakao K, Ozaki Y, Kimura K, Ako J, Noguchi T, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Mano T, Hirata K, Tanabe K, Shibata Y, Owa M, Tsujita K, Funayama H, Koku Tags: J Cardiol Source Type: research

To the Editor.
PMID: 32518031 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - June 7, 2020 Category: Cardiology Authors: Loughlin MJM, Loughlin SM Tags: J Cardiol Source Type: research

Clinical Predictors of Coronary Artery Plaque Progression by Quantitative Serial Assessment Using 320-Row Computed Tomography Coronary Angiography in Asymptomatic Patients with Type 2 Diabetes Mellitus.
CONCLUSIONS: Increase in HbA1c and HOMA-IR was associated with PP in asymptomatic patients with type 2 DM, whereas increase in LDL-C was correlated to increase in NC. PMID: 32518032 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - June 6, 2020 Category: Cardiology Authors: Tanaka T, Kishi S, Ninomiya K, Ishizawa T, Kikushima H, Tomii D, Koike H, Asami M, Yahagi K, Tanaka J, Komiyama K, Aoki J, Isogawa A, Tanabe K Tags: J Cardiol Source Type: research

Author's reply: careful statistical consideration to the inter-study reproducibility of iFR angio-coregistration.
PMID: 32513594 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - June 5, 2020 Category: Cardiology Authors: Shiono Y, Kubo T, Higashioka D, Akasaka T Tags: J Cardiol Source Type: research

Author's reply.
PMID: 32507610 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - June 4, 2020 Category: Cardiology Authors: Nagamatsu S, Sakamoto K, Tsujita K Tags: J Cardiol Source Type: research

Combined right and left ventricular mechanical dispersion enhance the arrhythmic risk stratification in hypertrophic cardiomyopathy.
CONCLUSIONS: In a cohort of subjects with HCM, LVMD and RVMD correlates with the presence of NSVT on ECG monitoring. Combined LVMD and RVMD may improve the risk stratification of HCM with NSVT. PMID: 32507507 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - June 2, 2020 Category: Cardiology Authors: Popa-Fotea NM, Micheu MM, Onciul S, Zamfir D, Dorobanţu M Tags: J Cardiol Source Type: research

Instantaneous wave-free ratio and angiography coregistration; statistical issue on reproducibility to avoid misinterpretation.
PMID: 32499092 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - June 1, 2020 Category: Cardiology Authors: Sabour S Tags: J Cardiol Source Type: research

Association between the antineutrophil cytoplasmic antibody and late coronary arterial occlusive disease in patients with Takayasu arteritis.
CONCLUSIONS: ANCA can be detected in a minority of patients with established TAK, and it may not contribute to the reclassification of AAV. Furthermore, ANCA positivity may be associated with late CAOD in patients with TAK. PMID: 32482328 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - May 30, 2020 Category: Cardiology Authors: Choi H, Kwon HC, Song JJ, Park YB, Lee SW Tags: J Cardiol Source Type: research

Structural heart intervention for prevention of embolic and hemorrhagic stroke: The new field of neurocardiology.
Abstract Cardiogenic stroke (CS), characteristic causes of which include atrial fibrillation (AF) and right-to-left shunting due to a patent foramen ovale (PFO), has a well-known tendency to be associated with a more extensive ischemic area. This may result in severe neurological damage, and require strict life-long antithrombotic therapy. However, the fact that some patients have problems complying with the requirement for extended oral antithrombotic treatment has motivated the development of alternative approaches for stroke prevention. Heart structures such as the left atrial appendage (LAA) and PFO are potent...
Source: Journal of Cardiology - May 29, 2020 Category: Cardiology Authors: Morino Y, Nakajima Y Tags: J Cardiol Source Type: research

Assessing influence of preoperative factors on delirium after cardiac surgery in elderly patients: Methodological issues.
PMID: 32482327 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - May 29, 2020 Category: Cardiology Authors: Cheng Y, Xue FS, Shao LJ, Liu SH Tags: J Cardiol Source Type: research

The impact of right ventricular dysfunction on the effectiveness of beta-blockers in heart failure with preserved ejection fraction.
This study aimed to clarify cardiac dysfunction affecting the effectiveness of beta-blockers in patients with HFpEF. METHODS: Four hundred and nine patients with HFpEF were enrolled retrospectively, and echocardiography and jugular venous pulse were examined to evaluate their cardiac function. The left ventricular (LV) ejection fraction, mean mitral e', mean mitral E/e' ratio, right ventricular (RV) systolic pressure, tricuspid annular plane systolic excursion, and jugular venous pulse waveform were used as indicators of LV contractility, LV relaxation ability, LV filling pressure, RV afterload, RV contractility, and ...
Source: Journal of Cardiology - May 28, 2020 Category: Cardiology Authors: Harada D, Asanoi H, Noto T, Takagawa J Tags: J Cardiol Source Type: research

Regional variability in Canadian routine care of type 2 diabetes, hypercholesterolemia, and hypertension: Results from the The Cardio-Vascular and metabolic treatments in Canada: Assessment of REal-life therapeutic value (CV-CARE) registry.
CONCLUSION: This is the first regional description of the CV-CARE cohort. Significant variations in both baseline profile and treatments were observed which could have an impact on long-term outcomes. PMID: 32473770 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - May 27, 2020 Category: Cardiology Authors: Goldenberg R, Bell A, Cheng W, Paron E, Fils-Aimé N, Burrows M, Blavignac J, Barakat M Tags: J Cardiol Source Type: research

A novel double-balloon catheter for percutaneous balloon pulmonary valvuloplasty under echocardiographic guidance only.
Abstract BACKGROUND: Percutaneous balloon pulmonary valvuloplasty (PBPV) is the procedure of choice for uncomplicated severe or symptomatic pulmonary stenosis. Echocardiography (echo)-guided PBPV can completely avoid the use of radiation and contrast agents compared to fluoroscopy-guided PBPV. Although we have confirmed that echo-guided PBPV is feasible in humans, the poor visibility of the traditional catheter under echo greatly limits the promotion of this new technology. METHODS: We produced a novel double-balloon catheter to make the catheter easy to be detected by echo through adding a guiding balloon at...
Source: Journal of Cardiology - May 22, 2020 Category: Cardiology Authors: Deng RD, Zhang FW, Zhao GZ, Wen B, Wang SZ, Ou-Yang WB, Liu Y, Xie YQ, Pan XB Tags: J Cardiol Source Type: research

Skeletal muscle index determined by bioelectrical impedance analysis is a determinant of exercise capacity and a prognostic predictor in patients with congenital heart disease.
Abstract BACKGROUND: Patients with congenital heart disease (CHD) reportedly have reduced exercise capacity. Underlying cardiac anatomy and a sedentary lifestyle are thought to be associated with exercise impairment. However, little has been reported regarding the relationship between quantitative body composition and exercise capacity. Bioelectrical impedance analysis (BIA) is a rapid and safe assessment method that has been widely used in clinical research. We hypothesized that bioelectrical impedance parameters are determinants of exercise capacity, and the skeletal muscle index (SMI) determined by BIA is a pro...
Source: Journal of Cardiology - May 18, 2020 Category: Cardiology Authors: Sato M, Inai K, Asagai S, Harada G, Shimada E, Sugiyama H Tags: J Cardiol Source Type: research

Association between calf girth and peripheral artery disease in the Atherosclerosis Risk in Communities Study.
CONCLUSIONS: Our findings revealed a linear association of calf girth with the prevalence of PAD among male participants in ARIC. PMID: 32439339 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - May 18, 2020 Category: Cardiology Authors: Liang J, Zhang H, Sun X, Liao L, Li X, Hu X, Du J, Zhuang X, Liao X Tags: J Cardiol Source Type: research

Plasma kinetics of mature PCSK9, furin-cleaved PCSK9, and Lp(a) with or without administration of PCSK9 inhibitors in acute myocardial infarction.
This study examined the effects of monoclonal anti-PCSK9 antibody on plasma PCSK9 and Lp(a) levels in acute myocardial infarction (MI). METHODS: Acute MI patients (n=36) were randomly divided into evolocumab (140mg; n=17) and non-evolocumab (n=19) groups. Changes in plasma PCSK9 and Lp(a) levels were monitored before and 1, 3, 5, 10, and 20 days after evolocumab administration. RESULTS: In the non-evolocumab group, plasma levels of mature PCSK9, furin-cleaved PCSK9, and Lp(a) (236.4±57.3ng/mL, 22.4±5.8ng/mL, and 19.2.±16.5mg/dL, respectively) significantly increased by day 3 (408.8±77.1ng/mL, p
Source: Journal of Cardiology - May 18, 2020 Category: Cardiology Authors: Nakamura A, Kanazawa M, Kagaya Y, Kondo M, Sato K, Endo H, Nozaki E Tags: J Cardiol Source Type: research

B-type natriuretic peptide and outcome in patients with apical hypertrophic cardiomyopathy.
Abstract BACKGROUND: Although elevated B-type natriuretic peptide (BNP) levels predict outcome in patients with hypertrophic cardiomyopathy (HCM), the association between BNP levels and outcome in patients with the apical phenotype of HCM remains unclear. We evaluated the impact of elevated BNP levels on outcome in a cohort of apical HCM patients. METHODS: Among 432 HCM patients, 144 with an apical phenotype were examined. Plasma BNP levels were measured at the time of the initial evaluation. RESULTS: The median (interquartile range) BNP level at initial evaluation in these patients was 188.5 (72.0-334.4...
Source: Journal of Cardiology - May 18, 2020 Category: Cardiology Authors: Shirotani S, Minami Y, Saito C, Haruki S, Hagiwara N Tags: J Cardiol Source Type: research

Impact of different coronary angioscopic findings on arterial healing one year after bioresorbable-polymer and second-generation durable-polymer drug-eluting stent implantation.
CONCLUSIONS: Compared with 2G DP-DES, BP-DES was less heterogeneous and well-covered NIC and less prevalence of the high-grade YCP implying optimal arterial healing. PMID: 32423653 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - May 15, 2020 Category: Cardiology Authors: Nojima Y, Adachi H, Ihara M, Kurimoto T, Okayama K, Sakata Y, Nanto S Tags: J Cardiol Source Type: research

Authors' reply.
ki M PMID: 32423654 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - May 15, 2020 Category: Cardiology Authors: Authors' reply. Tags: J Cardiol Source Type: research

Single Angio-Seal vascular closure device for transfemoral access exceeding 8F.
CONCLUSIONS: In selected cases, without availability of appropriate VCDs, a single Angio-SealTM-VIP 8F served as a feasible option to achieve sufficient hemostasis of transfemoral access exceeding 8F without relevant bleeding complications. Very low BMI, tall body-height, and severe atherosclerosis were identified to predispose to access site complications. PMID: 32402666 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - May 10, 2020 Category: Cardiology Authors: Frenzel F, Fries P, Shayesteh-Kheslat R, Buecker A, Massmann A Tags: J Cardiol Source Type: research

Echocardiography and MRI parameters associated with exercise capacity in patients after the arterial switch operation.
Abstract BACKGROUND: The arterial switch operation (ASO) for transposition of the great arteries has excellent survival, but a substantial number of patients suffer from a reduced exercise capacity. The goal of this study was to identify imaging parameters associated with a reduced exercise capacity in patients after ASO. METHODS: A retrospective analysis was performed of ASO patients who underwent cardiopulmonary exercise testing (CPET) between 2007 and 2017. Reduced exercise performance was defined as a reduced workload peak (Wpeak) with Z-score
Source: Journal of Cardiology - May 10, 2020 Category: Cardiology Authors: Warmerdam EG, Magni F, Leiner T, Doevendans PA, Sieswerda GT, van Wijk SW, Breur HM, Driesen BW, Grotenhuis HB, Takken T Tags: J Cardiol Source Type: research

Balloon pulmonary angioplasty improves quality of life in Japanese patients with chronic thromboembolic pulmonary hypertension.
This study quantified QOL among Japanese CTEPH patients and investigated whether balloon pulmonary angioplasty (BPA) improved QOL. METHODS AND RESULTS: We calculated the QOL scores of 45 CTEPH patients using the European Quality of Life Five Dimension scale (EQ-5D). The mean QOL score among 12 of those 45 not involved in any therapy except supplemental oxygen at the time of initial measurement was 0.673 ± 0.251. QOL was measured before and after BPA for 17 patients, and the mean significantly improved (QOL from 0.741 ± 0.195 to 0.802 ± 0.160, p 
Source: Journal of Cardiology - May 8, 2020 Category: Cardiology Authors: Minatsuki S, Kodera S, Kiyosue A, Saito A, Maki H, Hatano M, Takimoto E, Komuro I Tags: J Cardiol Source Type: research

Antithrombotic therapy in atrial fibrillation patients with coronary artery disease: shifting paradigm to a "less is more" concept regimen.
This article reviews current evidence and focuses on the optimal approach to antithrombotic treatment in patients with AF undergoing PCI in acute and chronic/stable phases. PMID: 32389534 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - May 7, 2020 Category: Cardiology Authors: Kawakami S, Yasuda S, Ogawa H Tags: J Cardiol Source Type: research

Impairment of coronary flow velocity reserve and global longitudinal strain in women with cardiac syndrome X and slow coronary flow.
Abstract BACKGROUND: Microvascular dysfunction (MVD) is associated with adverse prognosis and may account for abnormal stress tests and angina symptoms in women with cardiac syndrome X (CSX). The aim of our study was to assess MVD by coronary flow velocity reserve (CFVR) and left ventricular (LV) contractile function by LV global longitudinal strain (LVGLS) in CSX patients with respect to presence of slow coronary flow (SCF). It was of additional importance to evaluate clinical status of CSX patients using Seattle Angina Questionnaire. METHODS AND RESULTS: Study population included 70 women with CSX (mean age...
Source: Journal of Cardiology - May 6, 2020 Category: Cardiology Authors: Jovanovic I, Tesic M, Giga V, Dobric M, Boskovic N, Vratonjic J, Orlic D, Gudelj O, Tomasevic M, Dikic M, Nedeljkovic I, Trifunovic D, Nedeljkovic MA, Dedic S, Beleslin B, Djordjevic-Dikic A Tags: J Cardiol Source Type: research

Combined assessment of subtended myocardial volume and myocardial blood flow for diagnosis of obstructive coronary artery disease using cardiac computed tomography: A feasibility study.
This study aimed to evaluate the combined diagnostic performance of coronary artery stenosis-subtended myocardial volume (Vsub) and myocardial blood flow (MBFsub) on computed tomography (CT) for detecting obstructive coronary artery disease (CAD) assessed by invasive coronary angiography (ICA) and fractional flow reserve (FFR). METHODS: Thirty-nine patients who underwent coronary CT angiography (CTA) and stress dynamic myocardial CT perfusion (CTP) prior to ICA were enrolled. Obstructive CAD was defined as severe (≥70%) or moderate (30-69%) stenosis with FFR ≤0.8 on ICA. The Vsub was semi-automatically calculate...
Source: Journal of Cardiology - April 29, 2020 Category: Cardiology Authors: Tanabe Y, Kido T, Kurata A, Uetani T, Kuwahara N, Morikawa T, Kawaguchi N, Kido T, Nishimura K, Ikeda S, Yamaguchi O, Mochizuki T Tags: J Cardiol Source Type: research

Incidence, predictors and clinical significance of periprocedural myocardial injury in patients undergoing elective percutaneous coronary intervention.
CONCLUSIONS: PMI defined by troponin T levels>99th percentile URL correlated with an increased risk of cardiovascular events in stable CAD patients undergoing elective PCI. PMID: 32354492 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 27, 2020 Category: Cardiology Authors: Zhou Y, Chen Z, Ma J, Chen A, Lu D, Wu Y, Ren D, Zhang C, Dai C, Zhang Y, Qian J, Ge J Tags: J Cardiol Source Type: research

Diagnostic accuracy of stress myocardial computed tomography perfusion imaging to detect myocardial ischemia: a comparison with coronary flow velocity reserve derived from transthoracic Doppler echocardiography.
Abstract BACKGROUND: Our aim was to evaluate the ability of adenosine triphosphate (ATP)-stress myocardial computed tomography perfusion (CTP) imaging to detect myocardial ischemia in the left anterior descending artery (LAD) territory, and to compare this method with coronary flow velocity reserve (CFVR) measured by transthoracic Doppler echocardiography (TTDE). METHODS: ATP-stress CTP and CFVR were performed in 50 patients with stable angina pectoris. Myocardial ischemia assessed from CTP imaging was defined as qualitative visual perfusion defects and reduced myocardial blood flow (MBF) based on quantitativ...
Source: Journal of Cardiology - April 27, 2020 Category: Cardiology Authors: Kono T, Uetani T, Inoue K, Nagai T, Nishimura K, Suzuki J, Tanabe Y, Kido T, Kurata A, Mochizuki T, Ogimoto A, Okura T, Higaki J, Yamaguchi O, Ikeda S Tags: J Cardiol Source Type: research

Sodium-Glucose Cotransporter-2 inhibitors are potential therapeutic agents for treatment of non-diabetic heart failure patients.
Abstract Despite recent developments in various therapies, heart failure remains a leading cause of morbidity and mortality worldwide. New pharmacological approaches are therefore needed to improve the outcomes of patients with heart failure. Diabetes mellitus is an important risk factor for heart failure, but until recently there had been no evidence that hypoglycemic agents prevent heart failure. Sodium-glucose cotransporter-2 (SGLT2) inhibitors have now been shown to prevent cardiovascular events, especially hospitalization for heart failure, in three large randomized clinical trials: EMPA-REG OUTCOME, the CANV...
Source: Journal of Cardiology - April 24, 2020 Category: Cardiology Authors: Nakagawa Y, Kuwahara K Tags: J Cardiol Source Type: research

OPtical frequency domain imaging vs. INtravascular ultrasound in percutaneous coronary InterventiON in patients with Acute Coronary Syndrome: Study protocol for a randomized controlled trial.
CONCLUSION: The OPINION ACS trial outcomes will provide insights regarding the impact of OFDI-guided PCI on in-stent restenosis at 8 months in patients with ACS. PMID: 32340781 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 24, 2020 Category: Cardiology Authors: Otake H, Kubo T, Shinke T, Hibi K, Tanaka S, Ishida M, Kataoka T, Takaya T, Iwasaki M, Sonoda S, Ioji T, Akasaka T Tags: J Cardiol Source Type: research

Corrigendum to 'Relationship between optical coherence tomography-derived morphological criteria and functional relevance as determined by fractional flow reserve' [J. Cardiol. 71 (2018) 359-366/4].
PMID: 32336592 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 23, 2020 Category: Cardiology Authors: Usui E, Yonetsu T, Kanaji Y, Hoshino M, Yamaguchi M, Hada M, Fukuda T, Ohya H, Sumino Y, Hamaya R, Kanno Y, Murai T, Lee T, Kakuta T Tags: J Cardiol Source Type: research

Trends in long-term prognosis according to left ventricular ejection fraction after acute coronary syndrome.
Abstract AIMS: Our aim was to investigate trends in prognosis among survivors of acute coronary syndrome according to left ventricular ejection fraction during a 16-year period. METHODS: Data were derived from the Acute Coronary Syndrome Israeli Survey during the years 2000-2016. Patients aged 18 years and older were included in the analysis (N=11,725). Patients were classified into two groups based on their left ventricular ejection fraction: preserved (≥50%) and reduced (
Source: Journal of Cardiology - April 22, 2020 Category: Cardiology Authors: Yahud E, Tzuman O, Fink N, Goldenberg I, Goldkorn R, Peled Y, Lev E, Asher E Tags: J Cardiol Source Type: research

The genesis of ventricular arrhythmias in heart failure patients is based on alterations in cardiac mechanical, morphological, metabolic, electrophysiological properties, and neurohumoral remodeling.
PMID: 32334902 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 22, 2020 Category: Cardiology Authors: Spartalis M, Iliopoulos DC, Spartalis E, Athanasiou A, Paschou SA, Voudris V, Siasos G Tags: J Cardiol Source Type: research

Author's reply: The RyR2 - Targeting therapy against lethal arrhythmia.
PMID: 32307305 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 16, 2020 Category: Cardiology Authors: Kobayashi S, Yoshiga Y, Yano M Tags: J Cardiol Source Type: research

The Sequential Organ Failure Assessment (SOFA) score predicts mortality and neurological outcome in patients with post-cardiac arrest syndrome.
Abstract BACKGROUND: Patients experiencing out-of-hospital cardiac arrest (OHCA) and subsequent post-cardiac arrest syndrome are often compromised by multi-organ failure. The Sequential Organ Failure Assessment (SOFA) score has been used to predict clinical outcome of patients requiring intensive care for multi-organ failure. Thus, the assessment of SOFA score is recommended as a criterion for sepsis. Although post-cardiac arrest patients frequently develop sepsis-like status in ICU, there are limited reports evaluating the SOFA score in post-cardiac arrest patients. We investigated the predictive value of the SOF...
Source: Journal of Cardiology - April 15, 2020 Category: Cardiology Authors: Matsuda J, Kato S, Yano H, Nitta G, Kono T, Ikenouchi T, Murata K, Kanoh M, Inamura Y, Takamiya T, Negi K, Sato A, Yamato T, Inaba O, Morita H, Matsumura Y, Nitta J, Yonetsu T Tags: J Cardiol Source Type: research

The prevalence of sarcopenia and subtypes in cardiovascular diseases, and a new diagnostic approach.
Abstract BACKGROUND: The prevalence of sarcopenia and its subtypes, such as sarcopenic obesity, osteosarcopenia, and osteosarcopenic obesity, is little known in patients with cardiovascular diseases (CVD). METHODS: Physical, motor functional, and nutritional assessments were performed for 230 community-dwelling (CD) adults who came to receive a physical check-up, and 160 patients with CVD who were admitted to our hospital. Sarcopenia was diagnosed according to the Asian Working Group for Sarcopenia guidelines. The subtypes of sarcopenia were consecutively diagnosed according to increased body fat percentage a...
Source: Journal of Cardiology - April 15, 2020 Category: Cardiology Authors: Sasaki KI, Kakuma T, Sasaki M, Ishizaki Y, Fukami A, Enomoto M, Adachi H, Matsuse H, Shiba N, Ueno T, Fukumoto Y Tags: J Cardiol Source Type: research

Multi-biomarker mortality prediction in patients with aortic stenosis undergoing valve replacement.
CONCLUSIONS: A multiple biomarker approach might be useful for predicting postoperative mid-term mortality in patients with severe AS undergoing SAVR. Further large-scale prospective validation should be performed. PMID: 32273155 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 7, 2020 Category: Cardiology Authors: Spampinato RA, Bochen R, Sieg F, Weiss S, Kornej J, Haunschild J, von Aspern K, Strotdrees E, Noack T, Lehmann S, Etz C, Borger MA Tags: J Cardiol Source Type: research

Author's reply to the Letter to the Editor from Dr. Imamura: Impact of living alone on the care and outcomes of patients with ST-elevation myocardial infarction.
PMID: 32268987 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 5, 2020 Category: Cardiology Authors: Ohama A, Mizuguchi Y, Hashimoto S, Yamada T, Taniguchi N, Nakajima S, Hata T, Takahashi A Tags: J Cardiol Source Type: research

Clinical significance of arterial stiffness as a factor for hospitalization of heart failure with preserved left ventricular ejection fraction: a retrospective matched case-control study.
Abstract BACKGROUND: Previous studies have been conducted to identify characteristics of patients with heart failure with preserved ejection fraction (HFpEF), but the risk factors of HFpEF remain unclear. We investigated the associations between arterial stiffness and the risk of hospitalization for HFpEF patients. METHODS: For the case group, we enrolled patients with preserved EF who had been hospitalized for HF from April 2013 to March 2015 and examined the cardio-ankle vascular index (CAVI). For the control group, we enrolled outpatients with preserved EF and with hypertension, diabetes mellitus, dyslipid...
Source: Journal of Cardiology - April 5, 2020 Category: Cardiology Authors: Takagi K, Ishihara S, Kenji N, Iha H, Kobayashi N, Ito Y, Nohara T, Ohkuma S, Mitsuishi T, Ishizuka A, Shigihara S, Sone M, Tokuyama H, Omote T, Kikuchi A, Nakamura S, Yamamoto E, Ishikawa M, Amitani K, Takahashi N, Maruyama Y, Imura H, Sato N, Shimizu W Tags: J Cardiol Source Type: research

Blood biomarkers in patients with bicuspid aortic valve disease.
CONCLUSIONS: Higher NT-proBNP and hsTNT levels were associated with aortic valve disease in BAV patients. TGF-ß1 levels were lower in BAV patients than in the general population, and not related to aortic dilatation. Longitudinal data are needed to further investigate the prognostic value of biomarkers in these patients. PMID: 32265086 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 4, 2020 Category: Cardiology Authors: Bons LR, Geenen LW, van den Hoven AT, Dik WA, van den Bosch AE, Duijnhouwer AL, Siebelink HJ, Budde RPJ, Boersma E, Wessels MW, van de Laar IMBH, DeRuiter MC, Goumans MJ, Loeys BL, Roos-Hesselink JW Tags: J Cardiol Source Type: research

Detailed relationship between the living alone and worse clinical outcomes following ST-elevation myocardial infarction.
PMID: 32204982 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - March 20, 2020 Category: Cardiology Authors: Imamura T Tags: J Cardiol Source Type: research

Changes in characteristics and outcomes in Japanese patients with heart failure from the 2000s to the 2010s: The HIJ-HF cohorts.
Abstract BACKGROUND: The number of hospitalized patients with heart failure (HF) is increasing as a result of the increase in the elderly population in Japan. We evaluated changes in the characteristics and outcomes of HF patients hospitalized in the 2000s to the 2010s and discharged alive based on left ventricular ejection fraction (LVEF). METHODS: Pooled patient data were obtained from The Heart Institute of Japan Heart Failure studies (HIJ-HF I: 2001-2 and HIJ-HF II: 2013-4). We studied patients discharged alive from pooled data based on LVEF 
Source: Journal of Cardiology - March 18, 2020 Category: Cardiology Authors: Suzuki A, Shiga T, Kawashiro N, Hagiwara N, HIJ-HF II Investigators Tags: J Cardiol Source Type: research

Prognostic impact of the presence of on-duty cardiologist on patients with acute myocardial infarction admitted during off-hours.
CONCLUSIONS: The presence of an on-duty cardiologist is not a prognostic factor for patients hospitalized for AMI during off-hours in our medical system. Further prospective multicenter studies should confirm our results. PMID: 32199752 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - March 18, 2020 Category: Cardiology Authors: Marume K, Nagatomo K, Yamamoto N, Kaichi R, Mori T, Komaki S, Ishii M, Kusaka H, Toida R, Kurogi K, Nagamine Y, Takashio S, Arima Y, Sakamoto K, Yamamoto E, Kaikita K, Tsujita K Tags: J Cardiol Source Type: research

Quality indicators of palliative care for acute cardiovascular diseases.
CONCLUSION: In this study we developed 21 quality indicators, which were categorized into 2 major domains and 7 sub-categories. These indicators might be useful for many healthcare providers in the initiation and enhancement of palliative care practices for acute cardiovascular diseases in Japan. PMID: 32199753 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - March 18, 2020 Category: Cardiology Authors: Mizuno A, Miyashita M, Kohno T, Tokuda Y, Fujimoto S, Nakamura M, Takayama M, Niwa K, Fukuda T, Ishimatsu S, Kinoshita S, Oishi S, Mochizuki H, Utsunomiya A, Takada Y, Ochiai R, Mochizuki T, Nagao K, Yoshida S, Hayashi A, Sekine R, Anzai T Tags: J Cardiol Source Type: research

Determinants of Greater Peak radiation skin dose in percutaneous coronary intervention for chronic total occlusion.
Abstract BACKGROUND: Peak skin dose (PSD) is closely associated with skin radiation injuries such as skin ulcers in percutaneous coronary intervention (PCI). Although PSD is greater in PCI for chronic total occlusion (CTO) lesions as compared with non-CTO lesions, the determinants of PSD in CTO-PCI are not fully understood. The purpose of this study was to investigate the clinical factors associated with excess PSD in PCI for CTO. METHODS: The study population included a total of 220 CTO-PCI cases that were divided into a standard PSD group (
Source: Journal of Cardiology - March 17, 2020 Category: Cardiology Authors: Yamamoto K, Sakakura K, Hamamoto K, Hasegawa H, Tsukui T, Seguchi M, Taniguchi Y, Wada H, Momomura SI, Fujita H Tags: J Cardiol Source Type: research

Echocardiographic predictors of stress induced right ventricular diastolic dysfunction in non-severe chronic obstructive pulmonary disease.
CONCLUSION: There is a high prevalence of stress-induced RVDD in non-severe COPD patients with exertional dyspnea, free of overt cardiovascular disease. RAVI, RVWT, E/A, and E/e' ratio at rest may be used as predictors for stress RVDD and may facilitate patients' risk stratification and proper management. PMID: 32192845 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - March 16, 2020 Category: Cardiology Authors: Cherneva ZV, Denchev SV, Cherneva RV Tags: J Cardiol Source Type: research

Two-level analysis of risk factors for ischemic cardiovascular disease-A community-based study from Henan, China.
Abstract BACKGROUND: Ischemic cardiovascular disease (ICVD) has high incidence and high mortality worldwide. The studies of its risk factors were mostly concentrated on an individual level, and there are scarce studies on the two levels of risk factors which include individual and regional levels. METHODS: The data were obtained from a community-based study in 4 cities and 6 counties of Henan, China. Risk factors were initially screened by one-way analysis of variance or chi-square test. Then, they were re-analyzed using a two-level logistic regression model to construct a personal disease risk prediction mod...
Source: Journal of Cardiology - March 16, 2020 Category: Cardiology Authors: Zhang Y, Cao X, Duan F, Madhurapantula SV, Yin J, He G, Wang K, Liang S, Ma N, Nie W, Wang L, Duan H, Wang Y, Liu X, Jiao X, Li B, Song C, Wang K Tags: J Cardiol Source Type: research

Upper gastrointestinal bleeding in Japanese patients with ischemic heart disease receiving vonoprazan or a proton pump inhibitor with multiple antithrombotic agents: A nationwide database study.
Abstract BACKGROUND: Vonoprazan has been launched as an alternative to proton-pump inhibitors (PPIs). This was the first study to compare the occurrence of upper gastrointestinal bleeding (UGIB) with vonoprazan treatment to that with PPI treatment in patients with ischemic heart disease (IHD) taking ≥2 antithrombotic agents, including those receiving dual antiplatelet therapy (DAPT). METHODS: Using Japanese Diagnosis Procedure Combination data from 2016 to 2017, we identified 16,415 patients with IHD who were prescribed ≥2 antithrombotic agents, including new antiplatelet medication with concurrent vono...
Source: Journal of Cardiology - March 14, 2020 Category: Cardiology Authors: Tsujita K, Deguchi H, Uda A, Sugano K Tags: J Cardiol Source Type: research

Diagnostic accuracy of cardiac magnetic resonance imaging for cardiac sarcoidosis in complete heart block patients implanted with magnetic resonance-conditional pacemaker.
CONCLUSIONS: CMR can be a diagnostic tool for evaluating clinical CS in patients with CHB implanted with MRCP. LGE in the basal septum might provide the overall best diagnostic performance for clinical CS with CHB. PMID: 32184028 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - March 14, 2020 Category: Cardiology Authors: Orii M, Tanimoto T, Ota S, Takagi H, Tanaka R, Fujiwara J, Akasaka T, Yoshioka K Tags: J Cardiol Source Type: research