The predictive value of global longitudinal strain in patients with heart failure mid-range ejection fraction.
CONCLUSION: In patients with HFmrEF, LV GLS is associated with LVEF changes and subsequent cardiovascular death. Patients with HFrecEF had a lower risk of hospitalization for HF. PMID: 33234403 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - November 21, 2020 Category: Cardiology Authors: Chang WT, Lin CH, Hong CS, Liao CT, Liu YW, Chen ZC, Shih JY Tags: J Cardiol Source Type: research

Predictors of discordance between fractional flow reserve and resting full-cycle ratio in patients with coronary artery disease: Evidence from clinical practice.
CONCLUSIONS: RFR exhibited good diagnostic performance in the identification of functionally significant stenosis. However, RFR may overestimate functional severity in patients undergoing hemodialysis or in those with LAD lesions. Further prospective trials are required to demonstrate the non-inferiority of RFR to FFR. PMID: 33234404 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - November 21, 2020 Category: Cardiology Authors: Kato Y, Dohi T, Chikata Y, Fukase T, Takeuchi M, Takahashi N, Endo H, Nishiyama H, Doi S, Okai I, Iwata H, Isoda K, Okazaki S, Miyauchi K, Daida H, Minamino T Tags: J Cardiol Source Type: research

Long-term clinical outcomes and cause of death after endovascular treatment for femoropopliteal artery lesions.
Abstract BACKGROUND: Endovascular treatment (EVT) for femoropopliteal artery disease is common in clinical practice. However, little is known about its prognostic factors, causes of death, and long-term clinical outcomes. METHODS: Two hundred eighty-five consecutive patients (mean age, 72±8 years, 73% men) undergoing their first EVT for de-novo femoropopliteal artery disease from 2009 to 2018 were studied. Patients were divided in two groups according to the presence of critical limb ischemia (CLI). We evaluated the incidence of major adverse limb events (MALE) including clinically driven target vessel...
Source: Journal of Cardiology - November 20, 2020 Category: Cardiology Authors: Fukase T, Dohi T, Kato Y, Chikata Y, Takahashi N, Endo H, Doi S, Nishiyama H, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Daida H, Minamino T Tags: J Cardiol Source Type: research

Greetings from the new Editor-in-Chief.
PMID: 33229236 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - November 20, 2020 Category: Cardiology Authors: Takeishi Y Tags: J Cardiol Source Type: research

No signs of subclinical atherosclerosis after risk-reducing salpingo-oophorectomy in BRCA1/2 mutation carriers.
CONCLUSIONS: We found that, in BRCA1/2 mutation carriers, at 5 to 24 years follow-up, time since RRSO is not related to development of subclinical atherosclerosis. However, the follow-up period in these relatively young women might have been too short. PMID: 33229237 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - November 20, 2020 Category: Cardiology Authors: van Bommel MHD, de Jong MA, Steenbeek MP, Bots ML, van Westerop LLM, Hopman MTE, Hoogerbrugge N, de Hullu JA, Maas AHEM Tags: J Cardiol Source Type: research

Impact of no, distal, and proximal deep vein thrombosis on clinical outcomes in patients with acute pulmonary embolism: From the COMMAND VTE registry.
CONCLUSIONS: Acute PE with proximal DVT at diagnosis was associated with a higher risk for short-term mortality than in patients without DVT, while the risk for short-term mortality was not significantly different between distal DVT patients and patients without DVT. PMID: 33218901 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - November 17, 2020 Category: Cardiology Authors: Nishiwaki S, Morita Y, Yamashita Y, Morimoto T, Amano H, Takase T, Hiramori S, Kim K, Oi M, Akao M, Kobayashi Y, Toyofuku M, Izumi T, Tada T, Chen PM, Murata K, Tsuyuki Y, Saga S, Sasa T, Sakamoto J, Kinoshita M, Togi K, Mabuchi H, Takabayashi K, Shiomi H Tags: J Cardiol Source Type: research

Early electrocardiographic indices for predicting chronic doxorubicin-induced cardiotoxicity.
CONCLUSIONS: This study indicated that T-wave changes and QTa prolongation may be useful as an early indicator before the onset of CTRCD in patients with DOX-induced cardiotoxicity. PMID: 33214049 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - November 16, 2020 Category: Cardiology Authors: Kinoshita T, Yuzawa H, Natori K, Wada R, Yao S, Yano K, Akitsu K, Koike H, Shinohara M, Fujino T, Shimada H, Ikeda T Tags: J Cardiol Source Type: research

After seven years as Editor-in-Chief, it's time to pass the baton.
PMID: 33214050 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - November 16, 2020 Category: Cardiology Authors: Ito H Tags: J Cardiol Source Type: research

Implantable Cardioverter Defibrillator Therapy in Patients with Acute Decompensated Heart Failure with Reduced Ejection Fraction: An Observation from the KCHF Registry.
Abstract BACKGROUND: It remains unclear the clinical characteristics and prognosis of implantable cardioverter defibrillator (ICD) on prevention for sudden cardiac death (SCD) in Japanese patients with acute decompensated heart failure (ADHF) and reduced left ventricular ejection fraction (LVEF). We investigated the prevalence, clinical characteristics, and clinical outcomes in a contemporary large-scale Japanese ADHF registry. METHODS: Among the consecutive 3785 patients hospitalized for ADHF and discharged alive in the Kyoto Congestive Heart Failure registry, we identified 1409 patients with reduced LVEF (I...
Source: Journal of Cardiology - November 12, 2020 Category: Cardiology Authors: Hata R, Kato T, Yaku H, Morimoto T, Kawase Y, Yamamoto E, Inuzuka Y, Tamaki Y, Ozasa N, Yoshikawa Y, Kitai T, Yamashita Y, Iguchi M, Nagao K, Morinaga T, Furukawa Y, Kadota K, Sato Y, Kimura T Tags: J Cardiol Source Type: research

Clinical features of ST-segment elevation myocardial infarction in patients receiving welfare public assistance in urban area of Japan.
CONCLUSION: STEMI patients receiving welfare public assistance had poorer control of coronary risk, increased risk of fatal arrhythmia, and reduced systolic function than those not receiving welfare public assistance. It is necessary to have a system that can strengthen lifestyle management, such as diet and smoking cessation for the purpose of improving the prognosis of welfare recipients after AMI. PMID: 33183887 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - November 9, 2020 Category: Cardiology Authors: Watanabe S, Usui M Tags: J Cardiol Source Type: research

Detection of early stage of human coronary atherosclerosis by angioscopic imaging of collagen subtypes.
CONCLUSION: The results suggested that coronary segments stained red indicate no atherosclerosis, red and emerald-green in a mosaic pattern indicates initiation of atherosclerosis, emerald-green is early-stage atherosclerosis, pink is advanced stage of atherosclerosis, and no staining shows the end stage of atherosclerosis at least in superficial layer of coronary artery. Therefore, dye-staining angioscopy using Silius red and Fast green dyes in combination could be used to detect the early and advanced stage of atherosclerosis in superficial layer of human coronary artery. PMID: 33162263 [PubMed - as supplied by publ...
Source: Journal of Cardiology - November 5, 2020 Category: Cardiology Authors: Uchida Y, Shimoyama E, Hiruta N, Tabata T Tags: J Cardiol Source Type: research

Echocardiographic assessment of pulmonary arterial capacitance predicts mortality in pulmonary hypertension.
CONCLUSIONS: We have demonstrated that ePAC is a readily available echocardiographic marker that independently predicts mortality in PH, and have provided clinically relevant ranges by which to risk-stratify patients and predict mortality. PMID: 33158713 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - November 3, 2020 Category: Cardiology Authors: Papolos A, Tison GH, Mayfield J, Vasti E, DeMarco T Tags: J Cardiol Source Type: research

Current status of hybrid intravascular ultrasound and optical coherence tomography catheter for coronary imaging and percutaneous coronary intervention.
Abstract Both intravascular ultrasound (IVUS) and optical coherence tomography (OCT) play a crucial role in elucidating the pathophysiology of coronary artery disease (CAD) with the goal to improve patient outcomes of medical and/or interventional CAD management. However, no single intravascular imaging technique has been proven to provide complete and detailed evaluation of all CAD lesions due to some limitations. Although sequential use of multiple modalities may sometimes be performed, there may be issues related to risk, time, and cost. To overcome these problems, several hybrids involving dual-probe combined ...
Source: Journal of Cardiology - November 3, 2020 Category: Cardiology Authors: Terashima M, Kaneda H, Honda Y, Shimura T, Kodama A, Habara M, Suzuki T Tags: J Cardiol Source Type: research

Lack of association of antihypertensive drugs with the risk and severity of COVID-19: A meta-analysis.
Abstract BACKGROUND: The association of antihypertensive drugs with the risk and severity of COVID-19 remains unknown. METHODS AND RESULTS: We systematically searched PubMed, MEDLINE, The Cochrane Library, Cochrane Central Register of Controlled Trials (CENTRAL), ClinicalTrials.gov, and medRxiv for publications before July 13, 2020. Cohort studies and case-control studies that contain information on the association of antihypertensive agents including angiotensin-converting enzyme inhibitors (ACEIs), angiotensin II receptor blockers (ARBs), calcium-channel blockers (CCBs), β-blockers, and diuretics with ...
Source: Journal of Cardiology - November 2, 2020 Category: Cardiology Authors: Ren L, Yu S, Xu W, Overton JL, Chiamvimonvat N, Thai PN Tags: J Cardiol Source Type: research

Ying and Yang of Stat3 in pathogenesis of aortic dissection.
Abstract Aortic dissection (AD) is a medical emergency, in which acute destruction of aortic wall occurs with unknown etiology. Recent studies have uncovered the critical role of inteleukin-6 (IL-6) and inflammatory cells including macrophages in the disease mechanism of AD. IL-6 activates janus kinase and signal transducer and activator of transcription 3 (STAT3) to alter the gene expression program in many cell types, thus regulating various aspects of inflammatory response. We found that in human AD tissue, STAT3 was activated in infiltrating macrophages and in medial smooth muscle cells (SMCs), suggesting that...
Source: Journal of Cardiology - November 1, 2020 Category: Cardiology Authors: Aoki H, Majima R, Hashimoto Y, Hirakata S, Ohno-Urabe S Tags: J Cardiol Source Type: research

Transcatheter closure of patent foramen ovale: Current evidence and future perspectives.
Abstract Recent prospective controlled studies have demonstrated that transcatheter closure of a patent foramen ovale (PFO) reduces recurrent stroke risk in select patients, especially in patients younger than 60 years with PFO and embolic-appearing infarct and where no other mechanism of stroke was identified. Detection of PFO depends on the intensity of the Valsalva maneuver, and not all PFOs can be diagnosed using transesophageal echocardiography. Transthoracic contrast echocardiography using abdominal compression during the Valsalva maneuver is an easy method that can increase the detection sensitivity of PFO ...
Source: Journal of Cardiology - October 31, 2020 Category: Cardiology Authors: Akagi T Tags: J Cardiol Source Type: research

Disabilities of the arms, pinch strength, and mild cognitive impairment in patients with coronary artery disease.
Abstract BACKGROUND: We aimed to examine the relationship between the difficulty of activity using the arms and mild cognitive impairment (MCI), the relationship between the difficulty of activity using the arms and manual function, and cognitive function in patients with coronary artery disease (CAD). METHODS: We conducted a cross-sectional study of 263 non-dementia patients who met the study criteria from 2328 CAD patients. MCI was estimated with the Japanese version of the Montreal Cognitive Assessment (MoCA-J). The difficulty of activity using the arms was evaluated using the Disability of the Arm, Should...
Source: Journal of Cardiology - October 26, 2020 Category: Cardiology Authors: Ishihara K, Izawa KP, Kitamura M, Ogawa M, Shimogai T, Kanejima Y, Morisawa T, Shimizu I Tags: J Cardiol Source Type: research

Fate of lumen size in distal coronary segment following successful chronic total occlusion recanalization.
Abstract BACKGROUND: Restoration of anterograde blood flow leads to alterations in vascular wall stress that may influence lumen size distal to chronic total occlusion (CTO) lesions. We sought to assess changes in lumen diameter of segments distal to the stent segment of successfully recanalized CTO. METHODS: We analyzed 507 consecutive CTO cases with stent implantation that underwent follow-up angiography at a single high-volume center (mean follow-up of 13.5 months). Segments ≤40 mm distal to the stent edge were analyzed using quantitative coronary angiography. RESULTS: At follow-up, lumen di...
Source: Journal of Cardiology - October 26, 2020 Category: Cardiology Authors: Kwon O, Lee PH, Lee SW, Kweon J, Lee JY, Lee K, Kang DY, Ahn JM, Park DW, Kang SJ, Kim YH, Lee CW, Park SW, Park SJ Tags: J Cardiol Source Type: research

Angioscopic assessments and clinical outcomes one year after polymer-free biolimus A9-coated coronary stent implantation.
Abstract BACKGROUND: Polymer-free biolimus A9-coated coronary stent (DCS) has novel features which lead to the expectation of better arterial healing. However, comparisons of intravascular status between DCS and drug-eluting stents (DES), and robust real-word clinical assessments of DCS have been lacking to date. METHODS: From September 2017 to September 2018, we evaluated the intra-vascular status of 74 DCS implanted in 55 lesions from 43 patients using coronary angioscopy (CAS) approximately one year after implantation from a cohort of 219 lesions in 158 patients. We set 239 second-generation durable-polyme...
Source: Journal of Cardiology - October 26, 2020 Category: Cardiology Authors: Tsujimura T, Ishihara T, Okuno S, Iida O, Kurata N, Asai M, Masuda M, Okamoto S, Nanto K, Kanda T, Matsuda Y, Hata Y, Mano T Tags: J Cardiol Source Type: research

Relationship between oral health and physical frailty in patients with cardiovascular disease.
PMID: 33115609 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - October 25, 2020 Category: Cardiology Authors: Li H, Wang N, Chen Y Tags: J Cardiol Source Type: research

The impact of caffeine ingestion on different assessment modalities for myocardial ischaemia.
PMID: 33097390 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - October 20, 2020 Category: Cardiology Authors: Chong JW, Lee JC Tags: J Cardiol Source Type: research

Author's reply.
PMID: 33082058 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - October 17, 2020 Category: Cardiology Authors: Ishibuchi K, Fujii K Tags: J Cardiol Source Type: research

CHADS2 and CHA2DS2-VASc scores as predictors of platelet reactivity in acute coronary syndrome.
CONCLUSION: In ACS patients treated with clopidogrel following PCI, high CHADS2 and CHA2DS2-VASc scores correlated with HPR and lower scores correlated with OPR. Further studies are needed to evaluate our findings' clinical implications. PMID: 33067076 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - October 13, 2020 Category: Cardiology Authors: Asher E, Abu-Much A, Bragazzi NL, Younis A, Younis A, Masalha E, Goldkorn R, Mazin I, Fefer P, Barbash IM, Segev A, Beigel R, Matetzky S Tags: J Cardiol Source Type: research

Analysis of standards of quality for outcomes in acute heart failure patients directly discharged home from emergency departments and their relationship with the emergency department direct discharge rate.
cute;rate, Mecina AB, Traveria L, Agüera C, Takagi K, Möckel M, Pang PS, Collins SP, Mueller CE, Martín-Sánchez FJ, ICA-SEMES Research Group Abstract OBJECTIVE: Experts recommended that direct discharge without hospitalization (DDWH) for emergency departments (EDs) able to observe acute heart failure (AHF) patients should be>40%, and these discharged patients should fulfil the following outcome standards: 30-day all-cause mortality
Source: Journal of Cardiology - October 11, 2020 Category: Cardiology Authors: Miró Ò, López-Díez MP, Rossello X, Gil V, Herrero P, Jacob J, Llorens P, Escoda R, Aguiló S, Alquézar A, Tost J, Valero A, Gil C, Garrido JM, Alonso H, Lucas-Invernón FJ, Torres-Murillo J, Raquel-Torres-Gárate, Mecina AB, Traveria L, Agüera C, Ta Tags: J Cardiol Source Type: research

Patient perspectives on left main stem revascularization strategies, the OPINION-2 study.
CONCLUSIONS: Overall, patients who are informed about risk and benefits of each treatment modality clearly favor PCI over CABG and particularly value lower short-term morbidity while being aware of higher risk of repeat revascularization. Lower educational level was associated with a higher prevalence of psychosomatic phenotypes and a 14% preference for CABG. Educational and psychosocial background matter in the revascularization strategy decision-making process. PMID: 33041162 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - October 8, 2020 Category: Cardiology Authors: Nuis RJ, Jadoon A, van Dalen BM, Dulfer K, Snelder SM, Yazdi MT, Masdjedi K, den Dekker WK, Diletti R, Wilschut J, Daemen J, Lenzen MJ, Zijlstra F, Smits PC, Van Mieghem NM Tags: J Cardiol Source Type: research

Impact of age on mid-term clinical outcomes and left ventricular reverse remodeling after cardiac resynchronization therapy.
CONCLUSIONS: In elderly HF patients, CRT provided the same clinical benefits as in non-elderly HF patients, furthermore, there was a similar trend in LV reverse remodeling between the 2 groups. The present study demonstrated that the indication of CRT implantation should not be determined by age. PMID: 33036817 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - October 6, 2020 Category: Cardiology Authors: Yokoyama H, Shishido K, Tobita K, Moriyama N, Murakami M, Saito S Tags: J Cardiol Source Type: research

The predictive value of intraoperative transit-time flow measurement parameters for early graft failure in different target territories.
CONCLUSIONS: The overall early graft failure was about 3.5%. High PI value is a risk factor for early graft failure in not only overall grafts but in grafts of different target territories. DF might be more useful for the quality evaluation of grafts in left than in right target territories. PMID: 33012590 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - September 30, 2020 Category: Cardiology Authors: Zhang G, Zhao Z, Han Z, Gao Q, Liu J, Chen Y Tags: J Cardiol Source Type: research

Long-term efficacy and safety of anticoagulation after atrial fibrillation ablation: data from the JACRE registry.
CONCLUSIONS: Long-term incidence of thromboembolism was extremely low in patients with AF treated with CA, while that of major bleeding was not especially low. Clinical Trials Registry: UMIN000032829 / UMIN000032830. PMID: 33011056 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - September 29, 2020 Category: Cardiology Authors: Inoue K, Hirao K, Kumagai K, Kimura M, Miyauchi Y, Tsushima E, Ohishi M, Kimura K, Yasaka M, Yamaji H, Okawa K, Fujimoto M, Morishima I, Mine T, Shimizu W, Ohe M, Okumura K, JACRE Investigators Tags: J Cardiol Source Type: research

Dissection of coronary artery: A clinical overview.
Abstract Spontaneous coronary artery dissection (SCAD) is a rare but life-threatening disorder. SCAD is gaining importance as an emerging cause of acute coronary syndrome (ACS), especially in otherwise healthy young women. While SCAD and ACS show similarity in presentation, the management of SCAD differs to that of ACS. If not managed properly SCAD can lead to sudden death. This review examines the pathophysiology, clinical presentation, diagnostic algorithms, and the current and future management of SCAD. PMID: 32994072 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - September 25, 2020 Category: Cardiology Authors: Modaragamage Dona AC, Abuelgasim E, Abuelgasim B, Kermali M, Zahra SA, Hewage S, Harky A Tags: J Cardiol Source Type: research

Prediction of acute-coronary-syndrome using newly-defined R2-CHA2DS2-VASc score among patients with chest pain.
Abstract BACKGROUND: Chest-pain patients with no evidence of acute coronary syndrome might still be at risk for adverse outcomes. Adding renal function to the classic scoring of CHADS and CHA2DS2 VASC may improve risk stratification of chest-pain patients discharged from internal medicine wards after acute coronary syndrome (ACS) rule-out. METHODS: We accessed medical records of patients admitted to internal medicine wards during 2010-2016 and discharged following ACS rule-out. A R2CHA2DS2-VASc score model that included higher scores as kidney function deteriorated was calculated and compared to CHADS and CHA...
Source: Journal of Cardiology - September 24, 2020 Category: Cardiology Authors: Topaz G, Ben-Zvi E, Pereg D, Kitay-Cohen Y, Benchetrit S, Zitman-Gal T, Lotan S, Cohen-Hagai K Tags: J Cardiol Source Type: research

In vitro correlation between the effective and geometric orifice area in aortic stenosis.
CONCLUSION: As observed in clinical studies, the GOA was larger than the EOA, and a GOA between 1 and 1.2 cm² should not discard the possibility of severe aortic stenosis. PMID: 32958348 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - September 17, 2020 Category: Cardiology Authors: Adda J, Stanova V, Habib G, Rieu R Tags: J Cardiol Source Type: research

Cardiac catheterization for hemoptysis in a Children's Hospital Cardiac Catheterization Laboratory: A 15 year experience.
CONCLUSIONS: Cardiac catheterization was shown to have good diagnostic utility for hemoptysis especially in patients with underlying congenital heart disease. Despite the high mortality and recurrent hemoptysis rate, transcatheter interventions were effective in our cohort. PMID: 32951945 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - September 16, 2020 Category: Cardiology Authors: Sasaki T, Forbes TJ, Ross RD, Kawasaki Sasaki Y, Kobayashi D Tags: J Cardiol Source Type: research

Bleeding risks associated with anticoagulant therapies after percutaneous coronary intervention in Japanese patients with ischemic heart disease complicated by atrial fibrillation: A comparative study.
CONCLUSIONS: In this retrospective real-world evaluation of IHD patients with NVAF and PCI, DOAC-treated patients had a lower risk of developing clinically relevant bleeding compared with the VKA group. PMID: 32943280 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - September 13, 2020 Category: Cardiology Authors: Nakamura M, Yamashita T, Hayakawa A, Matsumoto T, Takita A, Hasegawa C, Uchino K, Sekine T, Iizuka T, Tanabe H, Kogure S Tags: J Cardiol Source Type: research

Clinical characteristics and in-hospital outcomes in patients aged 80 years or over with cardiac troponin-positive acute myocardial infarction -J-MINUET study.
CONCLUSIONS: J-MINUET showed different clinical characteristics between the aged and younger populations. The incidence of in-hospital death and cardiac failure in patients aged 80 years or over with AMI was poorer than their younger counterparts. PMID: 32938566 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - September 12, 2020 Category: Cardiology Authors: Soeda T, Okura H, Saito Y, Nakao K, Ozaki Y, Kimura K, Ako J, Noguchi T, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Hirohata A, Morita Y, Inoue T, Okamura A, Mano T, Hirata K, Tanabe K, Shibata Y, Owa M, Tsujita K, Funayama H, Kokubu N, Kozuma K, Tags: J Cardiol Source Type: research

A novel risk stratification system "Angiographic GRACE Score" for predicting in-hospital mortality of patients with acute myocardial infarction: Data from the K-ACTIVE Registry.
This study aimed to clarify the usefulness of GRACE risk score for risk stratification of Japanese AMI patients treated with early PCI and to evaluate a novel risk stratification system, "angiographic GRACE score," which is the GRACE risk score adjusted by the information of the culprit coronary artery and its flow at pre- and post-PCI, to improve its predicting availability. METHODS: The subjects were 1817 AMI patients who underwent PCI within 24 h of onset between October 2015 and August 2017 and were registered in Kanagawa Acute Cardiovascular (K-ACTIVE) Registry via survey form. The association be...
Source: Journal of Cardiology - September 9, 2020 Category: Cardiology Authors: Mitarai T, Tanabe Y, Akashi YJ, Maeda A, Ako J, Ikari Y, Ebina T, Namiki A, Fukui K, Michishita I, Kimura K, Suzuki H Tags: J Cardiol Source Type: research

Transient increase in blood thrombogenicity may be a critical mechanism for the occurrence of acute myocardial infarction.
Abstract Although the mechanism for the occurrence of acute myocardial infarction (MI) has been investigated by many pathological and clinical studies, it has not been adequately clarified yet. Although the disruption of vulnerable plaque is a well-known cause of acute MI, there are many silent plaque disruptions detected in the coronary artery by intravascular imaging studies. Therefore, many vulnerable plaques may disrupt and heal without causing acute MI. Some additional mechanisms other than the disruption of vulnerable plaque would be essential for the onset of acute MI. On the other hand, blood thrombogenici...
Source: Journal of Cardiology - September 9, 2020 Category: Cardiology Authors: Ueda Y, Kosugi S, Abe H, Ozaki T, Mishima T, Date M, Uematsu M, Koretsune Y Tags: J Cardiol Source Type: research

The ECG in sarcoidosis - a marker of cardiac involvement? Current evidence and clinical implications.
t L Abstract Sarcoidosis is a multisystem granulomatous disease of unknown etiology characterized by noncaseating granulomas. Cardiac involvement is often limiting patients' prognosis. Cardiac sarcoidosis can manifest with variant cardiac arrhythmias, of which atrioventricular (AV)-block-related bradycardia and ventricular tachycardias are the most common. Although cardiac sarcoidosis remains a histopathological diagnosis, the significance of imaging modalities, especially cardiac magnetic resonance imaging is increasing rapidly but mainly remains reserved for patients with a high suspicion due to a previous arrhy...
Source: Journal of Cardiology - September 7, 2020 Category: Cardiology Authors: Willy K, Dechering DG, Reinke F, Bögeholz N, Frommeyer G, Eckardt L Tags: J Cardiol Source Type: research

Morphological characteristics in diabetic cardiomyopathy associated with autophagy.
Abstract Diabetic cardiomyopathy, clinically diagnosed as ventricular dysfunction in the absence of coronary atherosclerosis or hypertension in diabetic patients, is a cardiac muscle-specific disease that increases the risk of heart failure and mortality. Its clinical course is characterized initially by diastolic dysfunction, later by systolic dysfunction, and eventually by clinical heart failure from an uncertain mechanism. Light microscopic features such as interstitial fibrosis, inflammation, and cardiomyocyte hypertrophy are observed in diabetic cardiomyopathy, but are common to failing hearts generally and a...
Source: Journal of Cardiology - September 5, 2020 Category: Cardiology Authors: Kanamori H, Naruse G, Yoshida A, Minatoguchi S, Watanabe T, Kawaguchi T, Tanaka T, Yamada Y, Takasugi H, Mikami A, Minatoguchi S, Miyazaki T, Okura H Tags: J Cardiol Source Type: research

Immune cell infiltration landscapes in pediatric acute myocarditis analyzed by CIBERSORT.
CONCLUSIONS: Infiltrating immune cell subsets detected by CIBERSORT analysis can reflect the time course of innate and adaptive immune responses in acute myocarditis. CIBERSORT may have the potential to characterize the detail of infiltrating immune cells in myocardial tissues and provide novel insights into the pathogenesis of acute myocarditis. PMID: 32891480 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - September 1, 2020 Category: Cardiology Authors: Kawada JI, Takeuchi S, Imai H, Okumura T, Horiba K, Suzuki T, Torii Y, Yasuda K, Imanaka-Yoshida K, Ito Y Tags: J Cardiol Source Type: research

Independent and cumulative association of clinical and morphological heart failure with long-term outcome after percutaneous coronary intervention.
Abstract BACKGROUND: Heart failure (HF) is a risk factor for adverse post-procedural outcome after revascularization; however, it is unclear how left ventricular systolic dysfunction (LVSD) and clinical HF symptoms affect percutaneous coronary intervention (PCI) outcomes. We investigated the characteristics and long-term outcomes of patients with clinical HF or LVSD after PCI. METHODS: This was a Japanese multicenter registry study of adult patients receiving PCI. Among 4689 consecutive patients who underwent PCI at 15 hospitals from January 2009 to December 2012, we analyzed 2634 (56.2%) with documented left...
Source: Journal of Cardiology - August 31, 2020 Category: Cardiology Authors: Kimura M, Kohno T, Sawano M, Heidenreich PA, Ueda I, Takahashi T, Matsubara T, Ueno K, Hayashida K, Yuasa S, Ohki T, Fukuda K, Kohsaka S Tags: J Cardiol Source Type: research

Left ventricular stiffness assessed by diastolic Wall strain predicts asymptomatic atrial high-rate episodes in patients with pacemaker implantation.
Abstract BACKGROUND: Cardiac implantable electronic device-detected atrial high-rate episodes (AHREs) have been reported to be associated with thromboembolic risks. The present study aimed to investigate the association of echocardiographic and clinical parameters with the occurrence of AHREs in patients with a dual-chamber pacemaker (PMI). METHODS: One hundred forty-seven patients (76 males, 75.2 ± 8.9 years) who did not show atrial tachyarrhythmia before the implantation of the PMI were studied. Diastolic wall strain (DWS) and other measurements were assessed during sinus rhythm using t...
Source: Journal of Cardiology - August 31, 2020 Category: Cardiology Authors: Kishima H, Mine T, Fukuhara E, Ishihara M Tags: J Cardiol Source Type: research

Optimal cut-off value of preprocedural geriatric nutritional risk index for predicting the clinical outcomes of patients undergoing endovascular revascularization for peripheral artery disease.
Abstract BACKGROUND: Malnutrition measured by the geriatric nutritional risk index (GNRI) was reported to be associated with poor prognosis for patients with peripheral artery disease (PAD). However, the optimal cut-off value of preprocedural GNRI for critical limb ischemia (CLI) and intermittent claudication (IC) is unknown. We aimed to determine its optimal cut-off value for CLI or IC patients requiring endovascular revascularization. METHODS: We explored data of 2246 patients (CLI: n = 1061, IC: n = 1185) registered in the Tokyo-taMA peripheral vascular intervention research COm...
Source: Journal of Cardiology - August 31, 2020 Category: Cardiology Authors: Yamaguchi T, Ueshima D, Utsunomiya M, Matsui A, Miyazaki T, Matsumoto M, Shimura T, Murata N, Komatsu Y, Tobita K, Fujimoto Y, Kodama T, Suzuki K, Anzai H, Jujo K, Higashitani M Tags: J Cardiol Source Type: research

Duration of atrial high-rate episodes and CHA2DS2-VASc score to predict cardiovascular and cerebrovascular events in patients with dual chamber permanent pacemakers.
Abstract BACKGROUND: Patients with atrial high-rate episodes (AHRE) have a high risk of cardiovascular and cerebrovascular events (CCE); however, the optimal cut-off threshold for AHRE duration and the prediction power of AHRE with CHA2DS2-VASc score is unknown. METHODS: We enrolled 355 consecutive patients undergoing dual chamber pacemaker implantations. The primary endpoint was subsequent CCE after AHRE ≥ 30 seconds, 1 minute, 2 minutes, 5 minutes, 6 hours, and 24 hours. AHRE was defined as>175 bpm (Medtronic, Dublin, Ireland) or>200 bpm (Biotronik, ...
Source: Journal of Cardiology - August 28, 2020 Category: Cardiology Authors: Chen JY, Lu WD Tags: J Cardiol Source Type: research

Mechanical Circulatory Support in Women.
Abstract A number of devices can now provide mechanical circulatory support (MCS) to patients with acute cardiogenic shock (CS) and chronic end-stage heart failure (HF). Women differ from men in pathophysiology and natural history of CS and HF, and are usually sicker at admission. Current evidence suggests that women benefit as much as men, if not more, from both temporary and durable MCS for appropriate indications. Yet, women have been under-represented in clinical trials of MCS devices. Limited evidence suggests that women benefit more from temporary MCS in CS associated with acute myocardial infarction. Howeve...
Source: Journal of Cardiology - August 28, 2020 Category: Cardiology Authors: Dayanand S, Martinez JM, Figueredo VM, Gupta S Tags: J Cardiol Source Type: research

Differential risk of incident cancer in patients with heart failure: A nationwide population-based cohort study.
This study included 128,441 HF patients without a history of cancer and 642,205 age- and sex-matched individuals with no history of cancer and HF between 1 January 2010 and 31 December 2015. RESULTS: During a median follow-up of 4.06 years, 11,808 patients from the HF group and 40,805 participants from the control were newly diagnosed with cancer (cumulative incidence, 9.2% vs. 6.4%, p 
Source: Journal of Cardiology - August 27, 2020 Category: Cardiology Authors: Kwak S, Kwon S, Lee SY, Yang S, Lee HJ, Lee H, Park JB, Han K, Kim YJ, Kim HK Tags: J Cardiol Source Type: research

Reducing the cost of managing patients with atrial fibrillation undergoing percutaneous coronary intervention with stenting.
Abstract Patients undergoing percutaneous coronary intervention (PCI) have an increased risk of both ischemic events and bleeding complications resulting from antithrombotic therapy. These events are particularly common in patients with a concomitant indication for oral anticoagulation, such as those with atrial fibrillation, and are associated with a substantial healthcare resource burden. Advances in procedural aspects of PCI have led to marked improvements in outcomes and a consequent reduction in the costs resulting from PCI-associated complications. Furthermore, recent randomized clinical trials have investig...
Source: Journal of Cardiology - August 25, 2020 Category: Cardiology Authors: Mehran R, Vogel B, Levy P Tags: J Cardiol Source Type: research

Author's reply: Can non-obstructive general angioscopy predict and aortic dissection before an attack?
PMID: 32859454 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - August 24, 2020 Category: Cardiology Authors: Nishi H, Kodama K Tags: J Cardiol Source Type: research

Association between discharge destination and mid-term mortality in octogenarian patients with ST-elevation myocardial infarction.
Abstract BACKGROUND: Owing to an increasing aging population, the number of elderly patients undergoing percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI) is escalating. The onset of STEMI in elderly patients may lead to increased frailty, resulting in failure of discharge to home despite survival. However, the association of discharge destination with prognosis has not been fully evaluated in this population. METHODS: Between January 2014 and December 2016, a total of 245 octogenarian STEMI survivors who underwent PCI (mean age, 84.4 years; male, 46.5%) were evaluated fro...
Source: Journal of Cardiology - August 23, 2020 Category: Cardiology Authors: Yoshioka N, Takagi K, Morishima I, Morita Y, Uemura Y, Inoue Y, Umemoto N, Shibata N, Negishi Y, Yoshida R, Tanaka A, Asano H, Watarai M, Ishii H, Murohara T, N-registry investigators Tags: J Cardiol Source Type: research

Remote ischemic preconditioning in a setting of electrical cardioversion of early onset persistent atrial fibrillation (RIP CAF trial): Rationale and study design.
CONCLUSION: Previously observed positive effect of RIP on atrial electrophysiology might be also implemented in a clinical setting of CV and therefore simplified and improve patient treatment. PMID: 32847754 [PubMed - as supplied by publisher] (Source: Journal of Cardiology)
Source: Journal of Cardiology - August 22, 2020 Category: Cardiology Authors: Kosiuk J, Langenhan K, Hindricks G, Bollmann A, Dagres N Tags: J Cardiol Source Type: research

Association of proteinuria with incident atrial fibrillation in the general Japanese population.
Abstract BACKGROUND: Although proteinuria has been associated with incident atrial fibrillation (AF) in Western countries, the association has not been investigated in the general Japanese population. METHODS: Participants aged ≥40 years who underwent the Japanese specific health check-up in Kanazawa City in 2013 and who completed a urine dipstick test were included in this study. Exposure was considered as presence or absence of proteinuria (≥1+). The outcome was incident AF confirmed by 12-lead electrocardiography. The Cox proportional hazard model was used to compute hazard ratio (HR) of proteinuria ...
Source: Journal of Cardiology - August 22, 2020 Category: Cardiology Authors: Tanaka Y, Tada H, Hara S, Hayashi K, Patel RB, Nishikawa T, Hashiba A, Takamura M, Greenland P, Kawashiri MA Tags: J Cardiol Source Type: research