Great Food Can Improve Brain Development (Even Before Birth)
What we eat – and what our kids eat – affects so much in life: appearance, energy, cognition, focus, mood, how often we get sick, how quickly we get better, how likely we are to develop a chronic disease, and how we age.
Every bite of food is either an investment in our future, a new debt we are taking out, or some of both.
There are many ways to enjoy the benefits of real food. One healthy way of eating that has been studied a lot is the Mediterranean diet, a diet rich in fruits, vegetables, whole grains, beans, nuts, seeds, fish, herbs, spices, and olive oil. Red meats, processed foods, and added sugars are limited.
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Source: Conversations with Dr Greene - September 5, 2023 Category: Child Development Authors: Alan Greene MD Tags: Dr. Greene's Blog Uncategorized Mediterranean Diet Pregnancy Nutrition Top Family Nutrition Source Type: blogs
A Discussion of Current Approaches Under Development for the Treatment of Aging
This open access paper tours a number of the present approaches under development to the treatment of aging as a medical condition, dwelling the most on therapies targeting senescent cells, either for destruction or to suppress the harmful senescence-associated secretory phenotype. We live in an exciting time of great potential, an age of accelerating progress in the capabilities of medical biotechnology, though it remains the case that too few people realize just how close we are to the widespread use of the first practical rejuvenation therapies.
Aging poses one of the greatest challenges for modern medicine, as...
Source: Fight Aging! - September 4, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, September 4th 2023
In conclusion, although the contribution of CRF to GrimAgeAccel and FitAgeAccel is relatively low compared to lifestyle-related factors such as smoking, the results suggest that the maintenance of CRF is associated with delayed biological ageing in older men.
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Release of Acetylcholine is Necessary for the Aging Brain to Compensate for a Lack of Neurogenesis
https://www.fightaging.org/archives/2023/09/release-of-acetylcholine-is-necessary-for-the-aging-brain-to-compensate-for-a-lack-of-neurogenesis/
Neurogenesis is the process by which new neurons are created by neural stem c...
Source: Fight Aging! - September 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Wanted: Division of Pharmacology, Physiology, and Biological Chemistry Branch Chief
We’re seeking a highly qualified scientist to serve as a branch chief in our Division of Pharmacology, Physiology, and Biological Chemistry (PPBC). This is a newly created position for the Division as it reorganizes into three branches. Applicants should have significant interest and experience in the scientific areas managed by the Division, which will continue to encompass all the existing research portfolios and will generally be arranged into branches covering physiology and clinical sciences, biochemistry and molecular pharmacology, and chemistry and chemical biology. For a listing of the current scientifi...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - August 30, 2023 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Job Announcements Source Type: blogs
A Perspective on the Coming Regulatory Shift to Approval of Drugs to Treat Aging
At some point, regulatory bodies that oversee the development of new medicine will accept that therapies can target causative mechanisms of aging in order to slow or reverse the progression of aging, and that there are viable ways to assess new treatments that treat aging. There is growing pressure from the academic community and longevity-focused biotech industry for the ability to run clinical trials to treat aging, rather than to treat one specific age-related disease.
While inevitable, this change will take some years to come to pass, and likely require greater consensus in the research community on reasonable a...
Source: Fight Aging! - August 29, 2023 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
And today in one of the stranger uses of my work ... " 130 Academic Words Ref from " Jonathan Eisen: Meet your microbes | TED Talk " "
Well, this is certainly a bit wacky.I was, well, Googling myself today and found this.130 Academic Words Ref from " Jonathan Eisen: Meet your microbes | TED Talk "
It seems like they took my Ted talkand got key words from it, and then use it to teach about those words in some sort of automated way. And, well, they got a few words wrong but actually the words they chose kind of capture a lot of what my talk was about. So here are a few screenshots of some of these key words
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This is from the" Tree of Life Blog "
of Jonathan Eisen, an evolutionary biologist and Open Access advocate
at the University of California,...
Source: The Tree of Life - August 24, 2023 Category: Microbiology Source Type: blogs
Ming Lei Departs Division for Research Capacity Building
It’s with mixed emotions that I share that Ming Lei left our Division for Research Capacity Building (DRCB) earlier this month to become senior associate vice president for research and graduate education at West Virginia University (WVU) Health Sciences. Ming also joined the faculty in WVU’s School of Medicine as vice dean for research and a professor in the department of microbiology, immunology, and cell biology.
Ming has been part of the NIH community since 2008, serving in key positions at the National Cancer Institute before joining NIGMS in 2018. During his tenure in DRCB, Ming led numerous initiatives to...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - August 24, 2023 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Director’s Messages NIGMS Staff News Source Type: blogs
Navigating Correlation and Causation with Life Sciences in the Age of AI
The following is a guest article by Alex Long, Head of Life Sciences Sales Strategy at Dell Technologies
In science, avoiding correlation without causation is a cornerstone of research methodology. This fundamental principle ensures that scientific conclusions are grounded in evidence rather than coincidental associations. However, as we venture into the Artificial Intelligence (AI) age, a new challenge emerges – that of “Correlation, not Creation.”
A classic example highlighting the distinction between correlation and causation is the seemingly bizarre connection between ice cream sales and swimming acci...
Source: EMR and HIPAA - August 24, 2023 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Analytics/Big Data C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System AI Hallucination Alex Long Correlation vs Causation Dell Technologies Generative AI Healthcare Scene Featured Human Source Type: blogs
The Next Pandemic May Be an AI one
By KIM BELLARD
Since the early days of the pandemic, conspiracy theorists have charged that COVID was a manufactured bioweapon, either deliberately leaked or the result of an inadvertent lab leak. There’s been no evidence to support these speculations, but, alas, that is not to say that such bioweapons aren’t truly an existential threat. And artificial intelligence (AI) may make the threat even worse.
Last week the Department of Defense issued its first ever Biodefense Posture Review. It “recognizes that expanding biological threats, enabled by advances in life sciences and biotechnology, are among the ...
Source: The Health Care Blog - August 23, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Policy AI Bioterrorism ChatGPT COVID Department of Defense Kim Bellard Source Type: blogs
Fight Aging! Newsletter, August 21st 2023
This study aimed to investigate the association between frailty index and circulating CAP2 concentration in 467 community-dwelling older adults (median age: 79; range: 65-92 years). The selected robust regression model showed that circulating CAP2 concentration was not associated with chronological age, as well as sex and education. However, circulating CAP2 concentration was significantly and inversely associated with the frailty index: a 0.1-unit increase in frailty index leads to ~0.5-point mean decrease in CAP2 concentration. Furthermore, mean CAP2 concentration was significantly lower in frail participants (i.e., fr...
Source: Fight Aging! - August 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Top 6 Companies Using AI In Drug Discovery And Development
What if coming up with a new drug could be measured in days rather than years? What if new medication would cost thousands instead of billions of dollars? Just look at how an AI pharma start-up developed a potential new drug in 46 days! Artificial intelligence technologies promise to speed up the process of drug discovery and development and make it more cost-effective. As the market is flourishing, and it takes time and effort to separate the wheat from the chaff, we collected the most promising AI pharma companies out there.
Drug design is a key area AI is revolutionizing. In one of our latest database projects, we de...
Source: The Medical Futurist - August 17, 2023 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Future of Pharma Genomics research clinical trials AI drug development medication drug discovery drug research cure Source Type: blogs
Celebrating 10 Years of Biomedical Beat
This August marks 10 years of the blog! Throughout the past decade, we’ve brought you blog posts that explore basic science topics, quiz your knowledge, showcase cool images, and more! Some of our most-read favorites include:
We’ve also interviewed over a hundred NIGMS-funded scientists about their research, mentorship, and careers. To celebrate 10 years, we went back to two of the first researchers featured on the blog to see what they’re up to now.
Exploring Enzymes With Dr. Emily Scott
Credit: University of Michigan.
Around the time we first fe...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - August 16, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Molecular Structures Cool Tools/Techniques Profiles Research Roundup RNA Source Type: blogs
Predicting Mildly Age-Slowing Drugs will be a Focus of Future Research
It is clear that new ways of analyzing large amounts of data via machine learning will be used extensively in the near future in the field of aging research, employed to speed up the process of finding new drug targets and small molecules that might alter metabolism to slightly slow aging. This will no doubt be a sizable component of the longevity industry, if we judge the near future by the present distribution of companies and efforts. I can't say that I think that is likely to produce sizable benefits in aging humans, however, when compared to the rational design of therapies to specifically repair underlying causes of ...
Source: Fight Aging! - August 16, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
What Is Pharmacology?
Credit: iStock.
Pharmacology is the study of how molecules, such as medicines, interact with the body. Scientists who study pharmacology are called pharmacologists, and they explore the chemical properties, biological effects, and therapeutic uses of medicines and other molecules. Their work can be broken down into two main areas:
Pharmacokinetics is the study of how the body acts on a medicine, including its processes of absorption, distribution, metabolism, and excretion (ADME).
Pharmacodynamics is the study of how a medicine acts in the body—both on its intended target and throughout all the organs and tissue...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - August 14, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Chemistry, Biochemistry and Pharmacology Common questions Genomics Medicines Miniseries Source Type: blogs
Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health."
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Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis?
https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/
Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't ...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
