Enhancing IEP Goal Development for Preschoolers with Autism: A Preliminary Study on ChatGPT Integration
CONCLUSION: The potential of ChatGPT as an effective tool for supporting special education teachers in developing high-quality IEP goals suggests promising implications for improving outcomes for preschool children with autism. Its integration may offer valuable assistance in tailoring individualized goals to meet the diverse needs of students in special education settings.PMID:38625490 | DOI:10.1007/s10803-024-06343-0 (Source: Journal of Autism and Developmental Disorders)
Source: Journal of Autism and Developmental Disorders - April 16, 2024 Category: Psychiatry Authors: Salih Rakap Serife Balikci Source Type: research

Correlates of Impairment and Growth in Families of Young Autistic Children
J Autism Dev Disord. 2024 Apr 16. doi: 10.1007/s10803-024-06339-w. Online ahead of print.ABSTRACTThe purpose of this project was to investigate potential correlates of family life impairment in families of young autistic children. This project incorporated measures of specific child and parent challenges in addition to a commonly used unidimensional measure of autism characteristics. In this way, we could assess whether such challenges explain variance in family life impairment, and whether their inclusion diminish associations between autism characteristics and family life impairment. Cross-sectional data were collected f...
Source: Journal of Autism and Developmental Disorders - April 16, 2024 Category: Psychiatry Authors: Kristen T MacKenzie Mario J Crown Jessie B Northrup Elizabeth Rutenberg Amy G Hartman Carla A Mazefsky Source Type: research

DHCR7 links cholesterol synthesis with neuronal development and axonal integrity
Biochem Biophys Res Commun. 2024 Apr 12;712-713:149932. doi: 10.1016/j.bbrc.2024.149932. Online ahead of print.ABSTRACTThe DHCR7 enzyme converts 7-DHC into cholesterol. Mutations in DHCR7 can block cholesterol production, leading to abnormal accumulation of 7-DHC and causing Smith-Lemli-Opitz syndrome (SLOS). SLOS is an autosomal recessive disorder characterized by multiple malformations, including microcephaly, intellectual disability, behavior reminiscent of autism, sleep disturbances, and attention-deficit/hyperactivity disorder (ADHD)-like hyperactivity. Although 7-DHC affects neuronal differentiation in ex vivo experi...
Source: Biochemical and Biophysical Research communications - April 16, 2024 Category: Biochemistry Authors: Shuya Miyazaki Nobuyuki Shimizu Hiroaki Miyahara Hitoshi Teranishi Ryohei Umeda Shinji Yano Tatsuo Shimada Hiroshi Shiraishi Kosaku Komiya Akira Katoh Akihiko Yoshimura Reiko Hanada Toshikatsu Hanada Source Type: research

Autistic traits and anthropomorphism: the case of vehicle fascia perception
Cogn Process. 2024 Apr 16. doi: 10.1007/s10339-024-01187-z. Online ahead of print.ABSTRACTIndividuals high in autistic traits can have difficulties with social interactions which may stem from difficulties with mentalizing abilities, yet findings from research investigating anthropomorphism of non-human objects in high trait individuals are inconsistent. Measuring emotions and attributes of front-facing vehicles, individuals scoring high versus low on the AQ-10 were compared for ratings of angry-happy, hostile-friendly, masculine-feminine, and submissive-dominant, as a function of vehicle size (large versus small). Our res...
Source: Cognitive Processing - April 16, 2024 Category: Neuroscience Authors: Leilani Forby Farid Pazhoohi Alan Kingstone Source Type: research

Enhancing IEP Goal Development for Preschoolers with Autism: A Preliminary Study on ChatGPT Integration
CONCLUSION: The potential of ChatGPT as an effective tool for supporting special education teachers in developing high-quality IEP goals suggests promising implications for improving outcomes for preschool children with autism. Its integration may offer valuable assistance in tailoring individualized goals to meet the diverse needs of students in special education settings.PMID:38625490 | DOI:10.1007/s10803-024-06343-0 (Source: Journal of Autism and Developmental Disorders)
Source: Journal of Autism and Developmental Disorders - April 16, 2024 Category: Psychiatry Authors: Salih Rakap Serife Balikci Source Type: research

Correlates of Impairment and Growth in Families of Young Autistic Children
J Autism Dev Disord. 2024 Apr 16. doi: 10.1007/s10803-024-06339-w. Online ahead of print.ABSTRACTThe purpose of this project was to investigate potential correlates of family life impairment in families of young autistic children. This project incorporated measures of specific child and parent challenges in addition to a commonly used unidimensional measure of autism characteristics. In this way, we could assess whether such challenges explain variance in family life impairment, and whether their inclusion diminish associations between autism characteristics and family life impairment. Cross-sectional data were collected f...
Source: Journal of Autism and Developmental Disorders - April 16, 2024 Category: Psychiatry Authors: Kristen T MacKenzie Mario J Crown Jessie B Northrup Elizabeth Rutenberg Amy G Hartman Carla A Mazefsky Source Type: research

STOMP during COVID-19: use of psychotropic medication in intellectual disabilities community services – pilot QI project
Sadia Zahid, Bushra Rauf, Rachel Lee, Hafsa Sheikh, Ashok Roy, Rani Pathania Advances in Mental Health and Intellectual Disabilities, Vol. ahead-of-print, No. ahead-of-print, pp.- A quantitative observational study was conducted. The purpose of this study is to examine the continuing adherence to the stopping over-medication of people with intellectual disability and/or autism guidelines for a cohort of outpatients seen in the outpatients’ clinics in the two teams who participated in this study to review the trend of psychotropic prescribing with a prescription indication along with the utilisation of non-pharmacologica...
Source: Advances in Mental Health and Intellectual Disabilities - April 16, 2024 Category: Disability Authors: Sadia Zahid Bushra Rauf Rachel Lee Hafsa Sheikh Ashok Roy Rani Pathania Source Type: research

Characterization of Initial Gastrointestinal Evaluation of Children with Autism Spectrum Disorder: A Descriptive Study
J Autism Dev Disord. 2024 Apr 15. doi: 10.1007/s10803-024-06318-1. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) is a multifactorial, pervasive neurodevelopmental disorder affecting 1 in 36 children in the United States. Given the rising prevalence and significant economic and social costs associated with ASD, it is critical that continued efforts be made towards better understanding the underlying etiology as well as management of the condition and its commonly associated comorbidities. It has been estimated that upwards of 70% of children with ASD have a positive history of gastrointestinal (GI) symptoms. ...
Source: Journal of Autism and Developmental Disorders - April 15, 2024 Category: Psychiatry Authors: Mojdeh Mostafavi Wael Sayej Source Type: research

Supporting neurodivergent nursing students in their practice placements
This article details the strengths that neurodivergent students can bring to nursing, as well as some of the challenges they may experience in practice settings. It outlines how practice assessors and supervisors can develop neuro-inclusive learning environments where neurodivergent students can thrive, as well as how to support them if they are not meeting their required proficiencies. The authors also discuss how appropriate reasonable adjustments can be implemented by using a collaborative approach with students.PMID:38616773 | DOI:10.7748/ns.2024.e12262 (Source: Nursing Standard)
Source: Nursing Standard - April 15, 2024 Category: Nursing Authors: Rachael Major Chloe Jackson Jade Wareham Jessica Pidcock Source Type: research

Developmental characteristics and accuracy of autism screening among two-year-old toddlers in the ECHO program
CONCLUSION: The M-CHAT-H accurately detects children at low risk for autism and children at increased risk with moderate accuracy. These findings support use of the M-CHAT-H in assessing autism risk and developmental and behavioral concerns in children.IMPACT: Previous literature regarding accuracy of the Modified Checklist for Autism in Toddlers (M-CHAT) is mixed but this study provides evidence that the M-CHAT performs well in detecting children at low risk for autism and consistently detects children with developmental delays and behavioral problems. The M-CHAT moderately detects children at increased risk for autism an...
Source: Pediatric Research - April 15, 2024 Category: Pediatrics Authors: Coral L Shuster Patricia A Brennan Brian S Carter Jennifer Check Viren D'Sa Joyce C Graff Jennifer Helderman Julie A Hofheimer Robert M Joseph Laura E Murphy Thomas G O'Connor T Michael O'Shea Michelle Pievsky Stephen J Sheinkopf Lauren C Shuffrey Lynne M Source Type: research

Supporting neurodivergent nursing students in their practice placements
This article details the strengths that neurodivergent students can bring to nursing, as well as some of the challenges they may experience in practice settings. It outlines how practice assessors and supervisors can develop neuro-inclusive learning environments where neurodivergent students can thrive, as well as how to support them if they are not meeting their required proficiencies. The authors also discuss how appropriate reasonable adjustments can be implemented by using a collaborative approach with students.PMID:38616773 | DOI:10.7748/ns.2024.e12262 (Source: Nursing Standard)
Source: Nursing Standard - April 15, 2024 Category: Nursing Authors: Rachael Major Chloe Jackson Jade Wareham Jessica Pidcock Source Type: research

No “cookie cutter rules”: best practice for social care staff in supporting autistic adults with relationships and sexuality
Claire Bates, Rose Matthews Advances in Autism, Vol. ahead-of-print, No. ahead-of-print, pp.- The purpose of this study is to explore the support needs surrounding intimate relationships and sexuality of autistic adults accessing funded social care in England.Semi-structured interviews with 15 autistic adults who were accessing funded social care examined their support needs surrounding intimate relationships and sexuality, with subsequent data analysis using reflexive thematic analysis.Four themes were generated: Help at hand, but not too close for comfort, No “cookie-cutter rules”: personalised, inclusive approaches...
Source: Advances in Autism - April 15, 2024 Category: Child Development Authors: Claire Bates Rose Matthews Source Type: research

Identifying the Correlates of Individual, Peer and Systemic Advocacy Among Parents of Children with Disabilities Who are Interested in Civic Engagement
AbstractParent advocacy is often critical for families of individuals with disabilities. Prior research has suggested that parent advocacy occurs across three levels: individual, peer, and systemic. Yet, little empirical research has identified the correlates of advocacy for each level. For this study, we examined the survey responses of 246 parents of individuals with disabilities who were interested in participating in a legislative advocacy program. Analyses included hierarchical regressions to identify the correlates of individual, peer, and systemic advocacy. Parents of children with autism were significantly more lik...
Source: Journal of Developmental and Physical Disabilities - April 15, 2024 Category: Disability Source Type: research

Genes, Vol. 15, Pages 492: Shedding a Light on Dark Genes: A Comparative Expression Study of PRR12 Orthologues during Zebrafish Development
This study explores the spatio-temporal expression of zebrafish PRR12 co-orthologs, prr12a and prr12b, as a first step to elucidate their function. In silico analysis reveals high evolutionary conservation in the DNA-interacting domains for both orthologs, with significant syntenic conservation observed for the prr12b locus. In situ hybridization and RT-qPCR analyses on zebrafish embryos and larvae reveal distinct expression patterns: prr12a is expressed early in zygotic development, mainly in the central nervous system, while prr12b expression initiates during gastrulation, localizing later to dopaminergic telencephalic a...
Source: Genes - April 15, 2024 Category: Genetics & Stem Cells Authors: Alessia Musc ò Davide Martini Matteo Digregorio Vania Broccoli Massimiliano Andreazzoli Tags: Article Source Type: research

Shared and divergent mental health characteristics of ADNP-, CHD8- and DYRK1A-related neurodevelopmental conditions
ConclusionsDespite shared associations with autism and intellectual disability, disruptive variants inADNP,CHD8, andDYRK1A may yield variable psychiatric phenotypes among children and adolescents. With replication in larger samples over time, efforts such as these may contribute to improved clinical care for affected children and adolescents, allow for earlier identification of emerging mental health difficulties, and promote early intervention to alleviate concerns and improve quality of life. (Source: Journal of Neurodevelopmental Disorders)
Source: Journal of Neurodevelopmental Disorders - April 15, 2024 Category: Neurology Source Type: research