Shared and divergent mental health characteristics of ADNP-, CHD8- and DYRK1A-related neurodevelopmental conditions

ConclusionsDespite shared associations with autism and intellectual disability, disruptive variants inADNP,CHD8, andDYRK1A may yield variable psychiatric phenotypes among children and adolescents. With replication in larger samples over time, efforts such as these may contribute to improved clinical care for affected children and adolescents, allow for earlier identification of emerging mental health difficulties, and promote early intervention to alleviate concerns and improve quality of life.
Source: Journal of Neurodevelopmental Disorders - Category: Neurology Source Type: research