Genome-wide analysis of two different regions of brain reveals the molecular changes of fertility related genes in rln3a < sup > -/- < /sup > mutants in male Nile tilapia (Oreochromis niloticus)
Gen Comp Endocrinol. 2024 Apr 29:114543. doi: 10.1016/j.ygcen.2024.114543. Online ahead of print.ABSTRACTRelaxin3 (rln3) has been associated with various emotional and cognitive processes, including stress, anxiety, learning, memory, motivational behavior, and circadian rhythm. Notably, previous report revealed that Rln3a played an indispensable role in testicular development and male fertility in Nile tilapia (Oreochromis niloticus). However, the underlying molecular mechanisms remain largely unknown. We found that Rln3a is expressed exclusively in the diencephalon* (Di*) of the brain. Deficiency of Rln3a resulted in a si...
Source: General and Comparative Endocrinology - May 1, 2024 Category: Endocrinology Authors: Tengfei Wu You Wu Yanlong Li Yiyun Du Saining Feng Deshou Wang Linyan Zhou Source Type: research

Testing a cognitive behavioural therapy program for anxiety in autistic adolescents: a feasibility study
CONCLUSION: This study suggests that the adaptation of the program 'Cool Kids - ASA' into an adolescent version is feasible and has the potential to show good effects thus enhancing the possibility of education, development and independence in future life for this group. Larger RCTs studies are, however, needed to examine the efficacy of the adolescent version.PMID:38690784 | DOI:10.1080/08039488.2024.2338206 (Source: Nordic Journal of Psychiatry)
Source: Nordic Journal of Psychiatry - May 1, 2024 Category: Psychiatry Authors: Tina R Kilburn Ronald M Rapee Heidi J Lyneham Mikael Thastum Per Hove Thomsen Source Type: research

Interpersonal process of dyadic coping in rheumatoid arthritis: a perspective from the Australian Rheumatology Association Database (ARAD)
CONCLUSION: Participants and spouse's own views of supportive and negative dyadic coping they receive intimately affects their psychological distress and relationship quality. Also, having a partner with rheumatoid arthritis also seemed to impact the spouse especially when there was a negative dyadic coping pattern.PMID:38692667 | DOI:10.3899/jrheum.2023-0664 (Source: J Rheumatol)
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Manasi M Mittinty Murthy N Mittinty Rachelle Buchbinder Marissa Lassere Vibhasha Chand Samuel Whittle Lyn March Catherine Hill Source Type: research

Risk factors for asthma-related hospital and intensive care admissions in children, adolescents and adults: a cohort study using primary and secondary care data
CONCLUSIONS: There are significant sociodemographic inequalities in the rates of asthma-related hospital and ICU admissions. Treating age-specific modifiable risk factors should be considered an integral part of asthma management, which could potentially reduce the rate of avoidable hospital admissions.PMID:38692709 | DOI:10.1136/bmjresp-2023-001746 (Source: Respiratory Care)
Source: Respiratory Care - May 1, 2024 Category: Respiratory Medicine Authors: Nikita Simms-Williams Prasad Nagakumar Rasiah Thayakaran Nicola J Adderley Richard Hotham Adel H Mansur Krishnarajah Nirantharakumar Shamil Haroon Source Type: research

Translational Research of the Acute Effects of Negative Emotions on Vascular Endothelial Health: Findings From a Randomized Controlled Study
CONCLUSIONS: In this randomized controlled experimental study, a brief provocation of anger adversely affected endothelial cell health by impairing endothelium-dependent vasodilation.PMID:38690710 | DOI:10.1161/JAHA.123.032698 (Source: Atherosclerosis)
Source: Atherosclerosis - May 1, 2024 Category: Cardiology Authors: Daichi Shimbo Morgan T Cohen Matthew McGoldrick Ipek Ensari Keith M Diaz Jie Fu Andrea T Duran Shuqing Zhao Jerry M Suls Matthew M Burg William F Chaplin Source Type: research

CaMKII activity and metabolic imbalance-related neurological diseases: Focus on vascular dysfunction, synaptic plasticity, amyloid beta accumulation, and lipid metabolism
Biomed Pharmacother. 2024 Apr 30;175:116688. doi: 10.1016/j.biopha.2024.116688. Online ahead of print.ABSTRACTMetabolic syndrome (MetS) is characterized by insulin resistance, hyperglycemia, excessive fat accumulation and dyslipidemia, and is known to be accompanied by neuropathological symptoms such as memory loss, anxiety, and depression. As the number of MetS patients is rapidly increasing globally, studies on the mechanisms of metabolic imbalance-related neuropathology are emerging as an important issue. Ca2+/calmodulin-dependent kinase II (CaMKII) is the main Ca2+ sensor and contributes to diverse intracellular signal...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - May 1, 2024 Category: Drugs & Pharmacology Authors: Jeongsik Yong Juhyun Song Source Type: research

Relevance of Emotion of Anxiety and Fear of Dentistry as Motivational Conflict in Oral Health Behaviors
CONCLUSION: Anxiety and fear of dentistry are not found to influence personal preventive oral care with reference to oral hygiene habits. Avoidance of dentistry factor of DFS is positively correlated with oral health behavior. Dental fear and anxiety do not impact oral health behaviors adversely.CLINICAL SIGNIFICANCE: In this era of youth and beauty, the utilization of professional dental care services is not affected by fear of invasive nature of dental procedures. Establishing the groundwork for knowledge regarding the scope of fear appeals in anxiety for dentistry may help to augment positive oral health behaviors for e...
Source: J Contemp Dent Pract - May 1, 2024 Category: Dentistry Authors: None Supriya Rajbir Singh Amra Ahsan Source Type: research

Long-term effects of alcohol consumption on anxiety in adults: A systematic review
CONCLUSIONS: A paucity of research on the longitudinal effects of alcohol consumption on anxiety was found, highlighting a significant gap in the research literature. Furthermore, existing research, primarily focussed on clinical subpopulations, has yielded mixed results. Further research is needed to explore the longitudinal dose dependent impact of alcohol consumption on anxiety using samples representative of national populations.PMID:38692070 | DOI:10.1016/j.addbeh.2024.108047 (Source: Addictive Behaviors)
Source: Addictive Behaviors - May 1, 2024 Category: Addiction Authors: Simon D'Aquino Akaash Kumar Benjamin Riordan Sarah Callinan Source Type: research

Psychological symptoms and health-related quality of life in intubated and non-intubated intensive care survivors: A multicentre, prospective observational cohort study
CONCLUSIONS: Nearly one-in-two (47 %) of the intubated and non-intubated ICU survivors reported clinically significant psychological symptoms at 3 and 12-month follow-ups. Overall, more than 30 % at 3-months and over 20 % at 12-months of the survivors in both groups had moderate or worse problems with their usual activities and mobility. The presence of psychological symptoms and HRQOL impairments was similar between the groups.PMID:38690186 | PMC:PMC11056421 | DOI:10.1016/j.ccrj.2023.10.011 (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - May 1, 2024 Category: Intensive Care Authors: Sumeet Rai Teresa Neeman Rhonda Brown Krishnaswamy Sundararajan Arvind Rajamani Michelle Miu Rakshit Panwar Mary Nourse Frank M P van Haren Imogen Mitchell Dale M Needham PRICE study investigators Source Type: research

Interpersonal process of dyadic coping in rheumatoid arthritis: a perspective from the Australian Rheumatology Association Database (ARAD)
CONCLUSION: Participants and spouse's own views of supportive and negative dyadic coping they receive intimately affects their psychological distress and relationship quality. Also, having a partner with rheumatoid arthritis also seemed to impact the spouse especially when there was a negative dyadic coping pattern.PMID:38692667 | DOI:10.3899/jrheum.2023-0664 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - May 1, 2024 Category: Rheumatology Authors: Manasi M Mittinty Murthy N Mittinty Rachelle Buchbinder Marissa Lassere Vibhasha Chand Samuel Whittle Lyn March Catherine Hill Source Type: research

The Association Between Religious Belief and Postoperative Psychological Status and Quality of Life of Parents of Children with Congenital Heart Disease: A Single Center Experience in Southeast China
This study aimed to investigate the association of religious belief on the postoperative psychological status and quality of life of parents of children with congenital heart disease (CHD). This was a cross-sectional study conducted at a provincial children ’s hospital in Fujian Province, China. Parents of postoperative children with CHD in the early postoperative period were included in this study between January 2020 and September 2020. The parents were divided into a religious belief group (n = 39) and a nonreligious belief group (n = 42) depending on whether they had religious beliefs. The Religious Coping Qu...
Source: Journal of Religion and Health - May 1, 2024 Category: Medical Ethics Source Type: research

Lower anxiety level to perform movements after revision anterior cruciate ligament reconstruction with lateral extra-articular tenodesis compared to without lateral extra-articular tenodesis
ConclusionsPatients who received LET in addition to revision ACLR have a lower anxiety level to perform movements than patients with revision ACLR alone, despite non-different subjective functional outcomes.Study designRetrospective cohort study, Level of evidence: III. (Source: Musculoskeletal Surgery)
Source: Musculoskeletal Surgery - May 1, 2024 Category: Orthopaedics Source Type: research

Evaluation of salivary stress markers and inflammatory cytokine levels in peri-implantitis patients
ConclusionThe study findings suggest that psychological stress may increase the inflammation associated with peri-implantitis by affecting cytokine expression levels.Clinical relevanceTo prevent peri-implantitis or reduce its prevalence, it could be beneficial to evaluate stress levels and identify individuals experiencing stress. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - May 1, 2024 Category: Dentistry Source Type: research

Frequencies of CYP2C19 and CYP2D6 gene variants in a German inpatient sample with mood and anxiety disorders
. (Source: World Journal of Biological Psychiatry)
Source: World Journal of Biological Psychiatry - May 1, 2024 Category: Psychiatry Authors: Maike Scherf-ClavelHeike WeberStefan UntereckerDaniel J. M üllerJürgen Deckerta Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital of Würzburg, Würzburg, Germanyb Campbell Family Mental Health Rese Source Type: research

Attitudes towards seeking psychological help among community dwelling older adults enrolled in primary care in Chile
Depression and anxiety are common mental disorders among older adults, but they are frequently underdiagnosed. Attitudes towards seeking professional mental health care is one of the barriers to access to trea... (Source: BMC Geriatrics)
Source: BMC Geriatrics - May 1, 2024 Category: Geriatrics Authors: Ximena Moreno and Francisco Moreno Tags: Research Source Type: research