Aerosol generation during surgical tracheostomy in a patient with COVID-19.
Authors: McGain F, Humphries RS, Mora JC, Timms P, Hill F, French C PMID: 33105919 [PubMed - as supplied by publisher] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - October 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Geolocated Twitter-based population mobility in Victoria, Australia, during the staged COVID-19 restrictions.
We describe preliminary evidence that geotagged Twitter data may be used to provide real-time population mobility data and information on the impact of restrictions on such mobility. PMID: 33105920 [PubMed - as supplied by publisher] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - October 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

In this issue of CCR.
Authors: Bellomo R PMID: 32900321 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Communicating medical information over the telephone in critical care.
Authors: Philpot SJ, Bilgrami I, Sullivan L PMID: 32900322 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Implications of direct oral anticoagulation and antiplatelet therapy in intensive care.
Authors: Willcox A, Ho L, Jones D PMID: 32900323 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Hydrocortisone in septic shock: is it worth it?
Authors: Young PJ PMID: 32900324 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

The cost-effectiveness of adjunctive corticosteroids for patients with septic shock.
CONCLUSIONS: Adjunctive hydrocortisone did not significantly affect longer term mortality, health-related quality of life, health care resource use or costs, and is unlikely to be cost-effective. PMID: 32900325 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Characteristics, treatment, outcomes and cause of death of invasively ventilated patients with COVID-19 ARDS in Milan, Italy.
CONCLUSIONS: Despite multiple advanced critical care interventions, COVID-19 ARDS was associated with prolonged ventilation and high short term mortality. Older age and pre-admission hypertension were key mortality risk factors. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT04318366. PMID: 32900326 [PubMed - indexed for MEDLINE] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Aerosol generation related to respiratory interventions and the effectiveness of a personal ventilation hood.
Authors: McGain F, Humphries RS, Lee JH, Schofield R, French C, Keywood MD, Irving L, Kevin K, Patel J, Monty J Abstract OBJECTIVE: To quantify aerosol generation from respiratory interventions and the effectiveness of their removal by a personal ventilation hood. DESIGN AND SETTING: Determination of the aerosol particle generation (in a single, healthy volunteer in a clean room) associated with breathing, speaking, wet coughing, oxygen (O2) 15 L/min via face mask, O2 60 L/min via nasal prongs, bilevel non-invasive positive-pressure ventilation (BiPAP) and nebulisation with O2 10 L/min. INTERVENTIONS: Aeros...
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Successful implementation of a short message service (SMS) as intensive care to family communication tool.
CONCLUSION: We successfully instituted real-time SMS updates. All surveyed participants agreed that these messages were reassuring, informative and easy to follow and that they would recommend the SMS service to other families. PMID: 32900328 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Cytokine and lipid metabolome effects of low-dose acetylsalicylic acid in critically ill patients with systemic inflammation: a pilot, feasibility, multicentre, randomised, placebo-controlled trial.
CONCLUSIONS: In ICU patients with SIRS, low-dose ASA did not significantly alter serum IL-6 concentrations, but it did affect plasma concentrations of certain lipid mediators. The ability to measure lipid mediators in clinical samples and to monitor the effect of ASA on their levels unlocks a potential area of biological investigation in critical care. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry (ACTRN 12614001165673). PMID: 32900329 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Outcomes of patients with subarachnoid haemorrhage admitted to Australian and New Zealand intensive care units following a cardiac arrest.
Authors: Heaney J, Paul E, Pilcher D, Lin C, Udy A, Young PJ Abstract OBJECTIVES: To describe the characteristics and outcomes of adults with a subarachnoid haemorrhage (SAH) admitted to Australian and New Zealand intensive care units (ICUs) with a cardiac arrest in the preceding 24 hours. DESIGN: Retrospective cohort study. SETTING: Study data from 144 Australian and New Zealand ICUs were obtained from the Australian and New Zealand Intensive Care Society Centre for Outcome and Resource Evaluation Adult Patient Database. PARTICIPANTS: A total of 439 of 11 047 (3.9%) patients admitted to an ICU with a S...
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

A pilot study of high frequency accelerometry-based sedation and agitation monitoring in critically ill patients.
CONCLUSIONS: We describe a novel approach to the analysis of wrist accelerometry data in critically ill patients. This technique not only appears to provide novel and continuous information about the depth of sedation or degree of agitation, it is also notable in its aptitude to anticipate impending transitions to higher RASS values. PMID: 32900331 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Recent exposure to smoking and COVID-19.
Authors: Landoni G, Moro M, Belletti A, Rovere-Querini P, Veronesi G, Ruggeri A, Lembo R, Dalessandro G, Galbiati C, Serpa Neto A, Zangrillo A PMID: 32900332 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Albumin as a drug: its biological effects beyond volume expansion.
Authors: Bihari S, Bannard-Smith J, Bellomo R Abstract Albumin is the most abundant and perhaps most important protein in human blood. Research has identified many of albumin's possible roles in modulating acid-base balance, modifying inflammation, maintaining vascular endothelial integrity, and binding endogenous and exogenous compounds. Albumin plays a key role in the homeostasis of vascular endothelium, offering protection from inflammation and damage to the glycocalyx. Albumin binds a diverse range of compounds. It transports, delivers and clears drugs, plus it helps with uptake, storage and disposal of potenti...
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Home ventilators for invasive ventilation of patients with COVID-19.
Authors: Monti G, Cremona G, Zangrillo A, Lombardi G, Sartini C, Sartorelli M, Colombo S, Serpa Neto A, Landoni G PMID: 32900334 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Physician drug prescribing preferences and availability for ventilation of patients with COVID-19.
Authors: Coombes ID, Dooley MJ, Townsend S, Carmichael S, Poole SG, Karamujic N, Richards B, Ziegenfuss M, Ankravs MJ, Uren H, Roberts JA, Holley A PMID: 32900335 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Sodium bicarbonate therapy for metabolic acidosis in critically ill patients: a survey of Australian and New Zealand intensive care clinicians.
CONCLUSIONS: This survey offers important insights into the preferences of Australian and New Zealand clinicians in regards to any future randomised controlled trial of bicarbonate therapy for metabolic acidosis in the critically ill. PMID: 32900336 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Smoking in critically ill patients with COVID-19: the Australian experience.
Authors: Plummer MP, Pellegrini B, Burrell AJ, Begum H, Trapani T, Udy AA, SPRINT-SARI Australia Investigators PMID: 32900337 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): a new variant of thrombotic microangiopathy?
Authors: Bobrova L, Kozlovskaya N, Korotchaeva Y, Bobkova I, Kamyshova E, Moiseev S PMID: 32900338 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Patients with pre-existing life-limiting illness in the intensive care unit: a point prevalence study.
Authors: Elderkin T, Bone A, Orford NR, Maiden MJ, George Institute for Global Health , Australian and New Zealand Intensive Care Society Clinical Trials Group PMID: 32900339 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Preventing code blue false alarms through a simple design change: a case study.
Authors: Doherty ZB, Faulkner PA, Fletcher JA, Fuzzard KL, Kippen RA, O'Sullivan BG PMID: 32900340 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - September 11, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Smoking in critically ill patients with COVID-19: the Australian experience.
Authors: Plummer MP, Pellegrini B, Burrell AJ, Begum H, Trapani T, Udy AA, SPRINT-SARI Australia Investigators PMID: 32634894 [PubMed - as supplied by publisher] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - July 10, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Physician drug prescribing preferences and availability for ventilation of patients with COVID-19.
Authors: Coombes ID, Dooley MJ, Townsend S, Carmichael S, Poole SG, Karamujic N, Richards B, Ziegenfuss M, Ankravs MJ, Uren H, Roberts JA, Holley A PMID: 32640769 [PubMed - as supplied by publisher] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - July 10, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Recent exposure to smoking and COVID-19.
Authors: Landoni G, Moro M, Belletti A, Rovere-Querini P, Veronesi G, Ruggeri A, Lembo R, Dalessandro G, Galbiati C, Serpa Neto A, Zangrillo A PMID: 32645763 [PubMed - as supplied by publisher] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - July 10, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Aerosol generation related to respiratory interventions and the effectiveness of a personal ventilation hood.
Authors: McGain F, Humphries RS, Lee JH, Schofield R, French C, Keywood MD, Irving L, Kevin K, Patel J, Monty J Abstract Objective: To quantify aerosol generation from respiratory interventions and the effectiveness of their removal by a personal ventilation hood. Design and setting: Determination of the aerosol particle generation (in a single, healthy volunteer in a clean room) associated with breathing, speaking, wet coughing, oxygen (O2) 15 L/min via face mask, O2 60 L/min via nasal prongs, bilevel non-invasive positive-pressure ventilation (BiPAP) and nebulisation with O2 10 L/min. Interventions: Aeros...
Source: Critical Care and Resuscitation - June 3, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

In this issue of CCR.
Authors: Bellomo R PMID: 32389100 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - May 12, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Qua pote quisque, in ea conterat arte diem: COVID-19 and Australian and New Zealand intensive care.
Authors: Udy A PMID: 32389101 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - May 12, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Opportunities and challenges of clustering, crossing over, and using registry data in the PEPTIC trial.
Authors: Young PJ, Bagshaw SM, Forbes AB, Nichol AD, Wright SE, Bellomo R, van Haren F, Litton E, Webb SA PMID: 32389102 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - May 12, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Comparative effectiveness research in critically ill patients: risks associated with mischaracterising usual care.
Authors: Applefeld WN, Wang J, Klein HG, Danner RL, Eichacker PQ, Natanson C Abstract Comparative effectiveness research can help guide the use of common, routine medical practices. However, to be safe and informative, such trials must include at least one treatment arm that accurately portrays current practices. While comparative effectiveness research is widely perceived as safe and to involve no or only minimal risks, these assumptions may not hold true if unrecognised deviations from usual care exist in one or more study arms. For critically ill subjects in particular, such practice deviations may increase the ...
Source: Critical Care and Resuscitation - May 12, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Temporal trend and survival impact of infection source among patients with sepsis: a nationwide study.
CONCLUSION: The temporal trends of sepsis incidence and mortality varied among different sources of sepsis, with lower respiratory tract being the highest burden among patients with sepsis. Furthermore, sources of sepsis and the presence of co-infection are independent predictors of mortality. Our results support source-specific preventive and treatment strategies for future sepsis management. PMID: 32389104 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - May 12, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Study protocol and statistical analysis plan for the Liberal Glucose Control in Critically Ill Patients with Pre-existing Type 2 Diabetes (LUCID) trial.
Authors: Poole AP, Finnis ME, Anstey J, Bellomo R, Bihari S, Biradar V, Doherty S, Eastwood G, Finfer S, French CJ, Ghosh A, Heller S, Horowitz M, Kar P, Kruger PS, Maiden MJ, Mårtensson J, McArthur CJ, McGuinness SP, Secombe PJ, Tobin AE, Udy AA, Young PJ, Deane AM, LUCID Study Investigators, ANZICS Clinical Trials Group Abstract BACKGROUND: Contemporary glucose management of intensive care unit (ICU) patients with type 2 diabetes is based on trial data derived predominantly from patients without type 2 diabetes. This is despite the recognition that patients with type 2 diabetes may be relatively more tolera...
Source: Critical Care and Resuscitation - May 12, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Risk prediction for severe acute kidney injury by integration of urine output, glomerular filtration, and urinary cell cycle arrest biomarkers.
CONCLUSION: In this prospective study, an integrative approach using UO, short term sCr change and/or urinary CCABs showed a satisfactory performance for the prediction of severe AKI development at 12 hours. PMID: 32389106 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - May 12, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Faecal diversion system usage in an adult intensive care unit.
CONCLUSION: Rectal tubes appear to be frequently inserted and can lead to major adverse events in critically ill patients. PMID: 32389107 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - May 12, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Continuous renal replacement therapy and its impact on hyperammonaemia in acute liver failure.
CONCLUSION: In Australian and New Zealand patients with ALF, CRRT is typically started early, before Stage 3 AKI or severe acidaemia, and in the presence hyperammonaemia. In these more severely ill patients, CRRT use was associated with prevention of extreme hyperammonaemia, which in turn, was associated with increased transplant-free survival. PMID: 32389108 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - May 12, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

A survey of extracorporeal membrane oxygenation practice in 23 Australian adult intensive care units.
Authors: Linke NJ, Fulcher BJ, Engeler DM, Anderson S, Bailey MJ, Bernard S, Board JV, Brodie D, Buhr H, Burrell AJC, Cooper DJ, Fan E, Fraser JF, Gattas DJ, Higgins AM, Hopper IK, Huckson S, Litton E, McGuinness SP, Nair P, Orford N, Parke RL, Pellegrino VA, Pilcher DV, Sheldrake J, Reddi BAJ, Stub D, Trapani TV, Udy AA, Hodgson CL, EXCEL Investigators PMID: 32389109 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - May 12, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Catheterisation of the brachial artery in children: should we be so concerned?
Authors: Hussey A, Raman S PMID: 32389110 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - May 12, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Characteristics, treatment, outcomes and cause of death of invasively ventilated patients with COVID-19 ARDS in Milan, Italy.
Conclusions: Despite multiple advanced critical care interventions, COVID-19 ARDS was associated with prolonged ventilation and high short term mortality. Older age and pre-admission hypertension were key mortality risk factors. Trial registration: ClinicalTrials.gov identifier: NCT04318366. PMID: 32353223 [PubMed - as supplied by publisher] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - May 1, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Home ventilators for invasive ventilation of patients with COVID-19.
Authors: Monti G, Cremona G, Zangrillo A, Lombardi G, Sartini C, Sartorelli M, Colombo S, Serpa Neto A, Landoni G PMID: 32353224 [PubMed - as supplied by publisher] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - May 1, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis.
Authors: Ciceri F, Beretta L, Scandroglio AM, Colombo S, Landoni G, Ruggeri A, Peccatori J, D'Angelo A, De Cobelli F, Rovere-Querini P, Tresoldi M, Dagna L, Zangrillo A Abstract We suggest the use of MicroCLOTS (microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome) as a new name for severe pulmonary coronavirus disease 2019 (COVID-19). We hypothesise that, in predisposed individuals, alveolar viral damage is followed by an inflammatory reaction and by microvascular pulmonary thrombosis. This progressive endothelial thromboinflammatory syndrome may also involve the microvascular bed of the br...
Source: Critical Care and Resuscitation - April 18, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

ANZICS guiding principles for complex decision making during the COVID-19 pandemic.
Authors: Warrillow S, Austin D, Cheung W, Close E, Holley A, Horgan B, Jansen M, Joynt G, Lister P, Moodie S, Nichol A, Nicholls M, Peake S, Skowronski G, Streat S, White B, Willmott L Abstract The global 2019 coronavirus disease (COVID-19) pandemic has led to major challenges in clinical decision making when the demand for intensive care exceeds local capacity. In order to promote consistent, transparent, objective and ethical decision making, the Australian and New Zealand Intensive Care Society (ANZICS) formed a committee to urgently develop guidelines outlining key principles that should be utilised during the ...
Source: Critical Care and Resuscitation - April 18, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Intensive care services during a pandemic: who should be driving the messaging?
Authors: Venkatesh B PMID: 32294806 [PubMed - as supplied by publisher] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - April 17, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Critically ill patients with COVID-19 in Hong Kong: a multicentre retrospective observational cohort study
Conclusion: Critically ill patients with COVID-19 often require a moderate duration of mechanical ventilation and vasopressor support. Most of these patients recover and survive to ICU discharge with supportive care using lung protective ventilation strategies, avoiding excess fluids, screening and treating bacterial co-infection, and timely intubation. Lower rather than upper respiratory tract viral burden correlates with clinical severity of illness. PMID: 32248675 [PubMed - as supplied by publisher] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - April 8, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Fast reshaping of intensive care unit facilities in a large metropolitan hospital in Milan, Italy: facing the COVID-19 pandemic emergency
Authors: Zangrillo A, Beretta L, Silvani P, Colombo S, Scandroglio AM, Dell’Acqua A, Fominskiy E, Landoni G, Monti G, Azzolini ML, Monaco F, Oriani A, Belleti A, Sartorelli M, Pallanch O, Saleh O, Sartini C, Nardelli P, Lombardi G, Morselli F, Scquizzato T, Frontera A, Ruggeri A, Scotti R, Assanelli A, Dagna L, Rovere-Querini P, Castagna A, Scarpellini P, Di Napoli D, Ambrosio A, Ciceri F, Tresoldi M Abstract At the end of 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak spread from China all around the world, causing thousands of deaths. In Italy, the hardest hit region was Lom...
Source: Critical Care and Resuscitation - April 2, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

In this issue of CCR.
Authors: Bellomo R PMID: 32102636 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

The implications of the PEPTIC trial for clinical practice.
Authors: Young PJ, Bagshaw SM, Bellomo R, Nichol AD, Wright SE PMID: 32102637 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Risk factors and outcomes of postoperative emergency response team activation: a matched case-control study.
CONCLUSION: We identified several patient and procedural characteristics associated with increased likelihood of postoperative ERT activation. ERT intervention is a marker for increased rates of postoperative complications and death. PMID: 32102638 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Haemodynamic effect of a 20% albumin fluid bolus in post-cardiac surgery patients.
CONCLUSION: In post-cardiac surgery patients, CI response to 20% albumin FBT was not congruous with MAP response over 30 minutes. Although hypotension was the main indication for FBT and a MAP response occurred in most of patients, such response was maximal during the bolus, dissipated in a few minutes, and was dissociated from the CI response. PMID: 32102639 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Prospective observational study of mechanical cardiopulmonary resuscitation, extracorporeal membrane oxygenation and early reperfusion for refractory cardiac arrest in Sydney: the 2CHEER study.
CONCLUSION: ECMO for refractory cardiac arrest shows promising survival rates if protocolised care is applied in conjunction with predefined selection criteria. PMID: 32102640 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Epidemiology and outcomes of obese critically ill patients in Australia and New Zealand.
CONCLUSION: We describe the epidemiology of obesity within a critically ill Australian and New Zealand population and confirm that some level of obesity is associated with lower mortality, both overall and across a range of diagnostic categories and important subgroups. Further research should focus on potential confounders such as nutritional status and the appropriateness of BMI in isolation as an anthropometric measure in critically ill patients. PMID: 32102641 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research