In this issue of CCR.
Authors: Bellomo R PMID: 32102636 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

The implications of the PEPTIC trial for clinical practice.
Authors: Young PJ, Bagshaw SM, Bellomo R, Nichol AD, Wright SE PMID: 32102637 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Risk factors and outcomes of postoperative emergency response team activation: a matched case-control study.
CONCLUSION: We identified several patient and procedural characteristics associated with increased likelihood of postoperative ERT activation. ERT intervention is a marker for increased rates of postoperative complications and death. PMID: 32102638 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Haemodynamic effect of a 20% albumin fluid bolus in post-cardiac surgery patients.
CONCLUSION: In post-cardiac surgery patients, CI response to 20% albumin FBT was not congruous with MAP response over 30 minutes. Although hypotension was the main indication for FBT and a MAP response occurred in most of patients, such response was maximal during the bolus, dissipated in a few minutes, and was dissociated from the CI response. PMID: 32102639 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Prospective observational study of mechanical cardiopulmonary resuscitation, extracorporeal membrane oxygenation and early reperfusion for refractory cardiac arrest in Sydney: the 2CHEER study.
CONCLUSION: ECMO for refractory cardiac arrest shows promising survival rates if protocolised care is applied in conjunction with predefined selection criteria. PMID: 32102640 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Epidemiology and outcomes of obese critically ill patients in Australia and New Zealand.
CONCLUSION: We describe the epidemiology of obesity within a critically ill Australian and New Zealand population and confirm that some level of obesity is associated with lower mortality, both overall and across a range of diagnostic categories and important subgroups. Further research should focus on potential confounders such as nutritional status and the appropriateness of BMI in isolation as an anthropometric measure in critically ill patients. PMID: 32102641 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Prevalence, characteristics, drainage and outcome of radiologically diagnosed pleural effusions in critically ill patients.
CONCLUSION: Pleural effusions are common in ICU patients and drainage is infrequent. One-third of effusions reaccumulate, even after drainage, and one in six patients with an effusion die in hospital. This information helps clinicians estimate resolution rates, advantages and disadvantages of effusion drainage, and overall prognosis. PMID: 32102642 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Autonomic function, postprandial hypotension and falls in older adults at one year after critical illness.
CONCLUSIONS: In older adults who were evaluated 3 and 12 months after ICU discharge, postprandial hypotension at 3 months was associated with an increased risk of subsequent falls, but the prevalence of postprandial hypotension decreased with time. PMID: 32102643 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Statistical analysis plan for the Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients with Acute Respiratory Failure trial.
CONCLUSION: This study will compare the effects of two sedatives in mechanically ventilated severely septic patients. In keeping with the guidance on statistical principles for clinical trials, we have developed a comprehensive statistical analysis plan by which we will adhere, as this will avoid bias and support transparency and reproducibility. TRIAL REGISTRATION: ClinicalTrials.gov (NCT01739933). PMID: 32102644 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Nitric oxide: a new role in intensive care.
Authors: Lee A, Butt W Abstract Inhaled nitric oxide has been used for 30 years to improve oxygenation and decrease pulmonary vascular resistance. In the past 15 years, there has been increased understanding of the role of endogenous nitric oxide on cell surface receptors, mitochondria, and intracellular processes involving calcium and superoxide radicals. This has led to several animal and human experiments revealing a potential role for administered nitric oxide or nitric oxide donors in patients with systemic inflammatory response syndrome or ischaemia-reperfusion injury, and in patients for whom exposure of blo...
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Sodium bicarbonate in 5% dextrose: can clinicians tell the difference?
CONCLUSION: When 100 mL of 8.4% sodium bicarbonate were diluted in 150 mL of D5W within a 250 mL polyolefin bag, clinicians were unable to correctly identify the contents of the bags. Our findings imply that sodium bicarbonate therapy can be successfully blinded. PMID: 32102646 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Stability of bicarbonate in normal saline: a technical report.
We examined seven samples of 100 mL 8.4% sodium bicarbonate diluted in 150 mL normal saline within a 250 mL polyolefin bag at time 0, 24 and 48 hours after preparation. We measured pH, Pco2, and bicarbonate concentration. RESULTS: Over a period of 48 hours, both pH and Pco2 decreased significantly (hourly rate of change, -0.001 [P = 0.043) and -0.098 [P
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Modifications to predefined rapid response team calling criteria: prevalence, characteristics and associated outcomes.
Authors: Chen QT, Hawker F PMID: 32102648 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - February 28, 2020 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

In this issue of CCR.
Authors: Bellomo R PMID: 31778626 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - November 30, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

O2, do we know what to do?
Authors: Young PJ, Bagshaw SM, Bailey M, Bellomo R, Mackle D, Pilcher D, Landoni G, Nichol A, Martin D PMID: 31778627 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - November 30, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Addressing high practice variability in reported management of burns.
Authors: Reade MC PMID: 31778628 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - November 30, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Pharmacokinetic data support 6-hourly dosing of intravenous vitamin C to critically ill patients with septic shock.
Authors: Hudson EP, Collie JT, Fujii T, Luethi N, Udy AA, Doherty S, Eastwood G, Yanase F, Naorungroj T, Bitker L, Abdelhamid YA, Greaves RF, Deane AM, Bellomo R Abstract OBJECTIVES: To study vitamin C pharmacokinetics in septic shock. DESIGN: Prospective pharmacokinetic study. SETTING: Two intensive care units. PARTICIPANTS: Twenty-one patients with septic shock enrolled in a randomised trial of high dose vitamin C therapy in septic shock. INTERVENTION: Patients received 1.5 g intravenous vitamin C every 6 hours. Plasma samples were obtained before and at 1, 4 and 6 hours after drug administration,...
Source: Critical Care and Resuscitation - November 30, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Low tidal volume ventilation during anaesthesia for major surgery: protocol and statistical analysis plan.
CONCLUSIONS: This is the first well powered study comparing the effect of low tidal volume ventilation versus high tidal volume ventilation during surgery on the incidence of postoperative respiratory complications in adult patients receiving moderate levels of PEEP. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry (ACTRN12614000790640). PMID: 31778630 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - November 30, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Small volume vacuum phlebotomy tubes: a controlled before-and-after study of a patient blood management initiative in an Australian adult intensive care unit.
CONCLUSION: SVTs reduce sampling volume without increasing laboratory error. Follow-on effects include reduced fall in haemoglobin concentration and severe anaemia. These correlations are absent in long admissions. PMID: 31778631 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - November 30, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

A pilot randomised controlled trial evaluating the pharmacodynamic effects of furosemide versus acetazolamide in critically ill patients.
Authors: Brown AJ, Cutuli SL, Eastwood GM, Bitker L, Marsh P, Bellomo R Abstract OBJECTIVE: To compare the physiological and biochemical effects of a single intravenous dose of furosemide or acetazolamide in critically ill patients. DESIGN: Single centre, pilot randomised controlled trial. SETTING: Large tertiary adult intensive care unit (ICU). PARTICIPANTS: Twenty-six adult ICU patients deemed to require diuretic therapy. INTERVENTION: Single dose of intravenous 40 mg furosemide or 500 mg acetazolamide. MAIN OUTCOME MEASURES: Data were collected on urine output, cumulative fluid balance, and s...
Source: Critical Care and Resuscitation - November 30, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

The burden of antibiotic allergies in adults in an Australian intensive care unit: the BASIS study.
CONCLUSION: Patients with AALs had twice the odds of receiving intravenous vancomycin and half the odds of receiving narrow spectrum β-lactams, which highlights the continued need for antimicrobial stewardship initiatives. PMID: 31778633 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - November 30, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Rapid haemodilution accelerates hypertonicity resolution in diabetic ketoacidosis: data from 25 intensive care admissions.
CONCLUSIONS: Major tonicity reductions often exceeding guidelines were common by ICU admission. Correcting DKA-induced hypertonicity at ≤ 3 mOsmol/kg/h requires controlled hyperglycaemia correction and, based on our data, avoidance of high fluid replacement rates; for example, sufficient to reduce haemoglobin concentrations by> 3 g/L/h, unless there is evidence of intravascular hypovolaemia. PMID: 31778634 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - November 30, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

The Plasma-Lyte 148 versus Saline (PLUS) study protocol amendment.
Authors: Hammond NE, Bellomo R, Gallagher M, Gattas D, Glass P, Mackle D, Micallef S, Myburgh J, Saxena M, Taylor C, Young P, Finfer S PMID: 31778635 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - November 30, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Therapeutic hypothermia and mortality in the intensive care unit: systematic review and meta-analysis.
CONCLUSIONS: This meta-analysis suggests that after decades of extensive research, TH has yet to show a beneficial effect on mortality across different critical care diseases. PMID: 31778636 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - November 30, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Using language descriptors to recognise delirium: a survey of clinicians and medical coders to identify delirium-suggestive words.
CONCLUSION: A comprehensive repertoire of delirium-suggestive words was validated using a multidisciplinary survey and new words suggested by respondents were added. The use of natural language processing algorithms may allow for earlier detection of delirium using our delirium library and be deployed for real-time decision making and clinical care. PMID: 31778637 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - November 30, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Survey of critical care practice in Australian and New Zealand burn referral centres.
Authors: Holley AD, Reade MC, Lipman J, Delaney A, Udy A, Lee R, Litton E, Cheung W, Turner A, Garside T, Macken L, Reddi B, Kol M, Kazemi A, Shah A, Townsend S, Cohen J PMID: 31778638 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - November 30, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Internet health information use by surrogate decision makers of patients admitted to the intensive care unit: a multicentre survey.
CONCLUSIONS: A substantial proportion of ICU NOK report using the internet as a source of health information. Internet use is associated with lower reported understanding, trust and influence of the ICU doctor. PMID: 31778639 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - November 30, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

In this issue of CCR.
Authors: Bellomo R PMID: 31462199 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - August 31, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Comparing apples and oranges: the vasoactive effects of hydrocortisone and studies investigating high dose vitamin C combination therapy in septic shock.
Authors: Fujii T, Udy AA, Venkatesh B PMID: 31462200 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - August 31, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Renal replacement therapy in the ICU: when should we STARRT?
Authors: Bellomo R PMID: 31462201 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - August 31, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Capacity to train and the intensive care workforce.
Authors: Board of the College of Intensive Care Medicine of Australia and New Zealand PMID: 31462202 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - August 31, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Statistical analysis plan for the Standard versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial.
CONCLUSION: To align with best practice standards for rigour, internal validity and transparency, we have developed a SAP for the STARRT-AKI trial before trial completion. The analysis will adhere to the SAP to avoid bias arising from knowledge of trial results. REGISTRATION: ClinicalTrials.gov identifier: NCT02568722 (6 October 2015). PMID: 31462203 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - August 31, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Targeted fibrinogen concentrate use in severe traumatic haemorrhage.
We examined 36 consecutive patients with trauma admitted to a level 1 trauma centre in Australia who received FC as part of their initial resuscitation. ROTEM analysis was conducted at various time points from emergency department (ED) admission to 48 hours after admission. The primary outcome was time to administration of FC after identification of hypofibrinogenaemia using ROTEM FIBTEM A5. Data were collected on quantity and timing of product transfusion, demographics, Injury Severity Score and laboratory values of coagulation. Spearman rank order correlation was used to determine the correlation between FIBTEM A5 and Cl...
Source: Critical Care and Resuscitation - August 31, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

The epidemiology of in-hospital cardiac arrests in Australia: a prospective multicentre observational study.
CONCLUSION: Among seven Australian hospitals, IHCAs were infrequent, mostly occurred in older medical patients early in the hospital admission. Most were non-shockable, ICU therapy was extensive and nearly two-thirds of patients died in hospital. Further strategies are needed to prevent and improve ICHA outcomes. PMID: 31462205 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - August 31, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Characteristics, management and outcomes of patients with acute liver failure admitted to Australasian intensive care units.
CONCLUSION: POD is the major cause of ALF in Australian and New Zealand liver transplant centres and is a unique and separate form of ALF. It has a much lower associated mortality and treatment with liver transplantation than non-POD ALF. Non-POD patients have a poor prognosis in the absence of transplantation. PMID: 31462206 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - August 31, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Aboriginal and Torres Strait Islander patients requiring critical care: characteristics, resource use, and outcomes.
Authors: Secombe P, Brown A, McAnulty G, Pilcher D Abstract OBJECTIVE: To provide a contemporary description of the demographics, characteristics and outcomes of critically ill Indigenous patients in Australia. DESIGN, SETTING AND PARTICIPANTS: Retrospective database review using the Australian and New Zealand Intensive Care Society Adult Patient Database for intensive care unit (ICU) admissions in 2017-18. Characteristics of critically ill Indigenous patients were compared with non-Indigenous patients. MAIN OUTCOME MEASURES: Primary outcome was hospital mortality. Secondary outcomes examined demographics a...
Source: Critical Care and Resuscitation - August 31, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Cumulative radiation in critically ill patients: a retrospective audit of ionising radiation exposure in an intensive care unit.
CONCLUSION: Most ICU patients received low CED during their stay, with the majority receiving less than the recommended limit for members of the public (1 mSv). These results may educate clinicians regarding radiation exposures in ICU settings, highlighting the relatively low exposures and thus low risk to the patients. PMID: 31462208 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - August 31, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Duration of intravenous vitamin C therapy is a critical consideration.
Authors: Carr AC PMID: 31462209 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - August 31, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

In this issue of CCR.
Authors: Bellomo R PMID: 31142235 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - June 1, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Fentanyl versus morphine for analgo-sedation in mechanically ventilated adult ICU patients.
Authors: Casamento A, Bellomo R PMID: 31142236 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - June 1, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Is sepsis treatment heating up?
Authors: Young PJ PMID: 31142237 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - June 1, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Sepsis uncouples serum C-peptide and insulin levels in critically ill patients with type 2 diabetes mellitus.
Authors: Bitker L, Cutuli SL, Cioccari L, Osawa EA, Toh L, Luethi N, Young H, Peck L, Eastwood GM, Mårtensson J, Bellomo R Abstract OBJECTIVE: To assess the effects of sepsis and exogenous insulin on C-peptide levels and C-peptide to insulin ratios in intensive care unit (ICU) patients with type 2 diabetes mellitus (T2DM). DESIGN, SETTING AND PARTICIPANTS: In this prospective, observational, single-centre study, we enrolled 31 ICU-admitted adults with T2DM. We measured serum C-peptide and insulin levels during the first 3 days of ICU stay and recorded characteristics of exogenous insulin therapy. Patients...
Source: Critical Care and Resuscitation - June 1, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Prevalence of low-normal body temperatures and use of active warming in emergency department patients presenting with severe infection.
Authors: Gouldthorpe OT, Pilcher DV, Bellomo R, Udy AA Abstract OBJECTIVE: To describe the prevalence of low-normal body temperatures in emergency department (ED) patients presenting with severe infection, and to determine whether active warming is used in this setting. DESIGN, SETTING AND PARTICIPANTS: We performed a singlecentre retrospective cohort study in ED patients with community-acquired infection who required admission to the intensive care unit (ICU). Temperatures recorded from presentation up until 24 hours in the ICU were extracted from the patients' clinical records. Body temperatures were then cla...
Source: Critical Care and Resuscitation - June 1, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Perceived Discomfort in Patients admitted to Intensive Care (DETECT DISCOMFORT 1): a prospective observational study.
CONCLUSION: Patients admitted to our ICU reported low overall discomfort. There was an inverse relationship between age and perceived discomfort. The translated questionnaire for measuring discomfort performed well in our setting and could be applied to the Australian population. PMID: 31142240 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - June 1, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Persistent critical illness: baseline characteristics, intensive care course, and cause of death.
Authors: Darvall JN, Boonstra T, Norman J, Murphy D, Bailey M, Iwashyna TJ, Bagshaw SM, Bellomo R Abstract OBJECTIVES: Persistent critical illness (PerCI) is associated with high mortality and discharge to institutional care. Little is known about factors involved in its progression, complications and cause of death. We aimed to identify such factors and the time when the original illness was no longer the reason for intensive care unit (ICU) stay. DESIGN: Retrospective matched case-control study using an accepted PerCI definition (> 10 days in ICU). SETTING: Single-centre tertiary metropolitan ICU. ...
Source: Critical Care and Resuscitation - June 1, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Vitamin C, Hydrocortisone and Thiamine in Patients with Septic Shock (VITAMINS) trial: study protocol and statistical analysis plan.
CONCLUSION: The VITAMINS trial will determine whether combination therapy of vitamin C, thiamine and hydrocortisone when compared with hydrocortisone increases vasopressor-free hours in critically ill patients with septic shock. The conduct of this study will provide important information on the feasibility of studying this intervention in a phase 3 trial. TRIAL REGISTRATION: ClinicalTrials.gov, identification No. NCT03333278. PMID: 31142242 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - June 1, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Assessment of the College of Intensive Care Medicine's capacity to train: a survey of trainees and directors.
CONCLUSION: This report has provided an assessment of the available resources within Australia and New Zealand for training doctors in intensive care medicine, and has identified significant limitations and concerns among trainees and ICU directors regarding the capacity to train. The findings call for a review of the training program, including a determination of optimal numbers of training positions. PMID: 31142243 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - June 1, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

Haemodynamic response to fluid boluses in children after cardiac surgery: a technical report.
Authors: Gelbart B, Bitker L, Segal A, Hutchinson A, Soh N, Maybury T Abstract OBJECTIVE: To describe the haemodynamic response to fluid boluses (FB) in children after cardiac surgery. DESIGN: A prospective observational pilot study. SETTING: Single-centre, paediatric cardiac intensive care unit. PARTICIPANTS: Children after cardiac surgery. INTERVENTIONS: FB of 0.9% saline, 4% albumin or modified ultrafiltrate blood administered in less than 30 minutes. MAIN OUTCOME MEASURES: Heart rate, arterial blood pressure, central venous pressure, oesophageal temperature, and end-tidal carbon dioxide were...
Source: Critical Care and Resuscitation - June 1, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

A practice survey of airway management in Australian and New Zealand intensive care units.
CONCLUSION: Variation of practices in intubation was noted in the participants. Approximately 61% of respondents supported the development of Australian and New Zealand ICU airway management guidelines, and 80% supported mandatory airway management training. PMID: 31142245 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - June 1, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research

In this issue of CCR.
Authors: Bellomo R PMID: 30857504 [PubMed - in process] (Source: Critical Care and Resuscitation)
Source: Critical Care and Resuscitation - March 13, 2019 Category: Intensive Care Tags: Crit Care Resusc Source Type: research