Randomized clinical trial of non-antibiotic prophylaxis with d-Mannose plus Proanthocyanidins vs. Proanthocyanidins alone for urinary tract infections and asymptomatic bacteriuria in de novo kidney transplant recipients: The Manotras study
CONCLUSIONS: Non-antibiotic therapy is an unmet need to prevent UTI after kidney transplantation; however, the use of d-Mannose plus PAC does not seem capable to prevent it.PMID:38637262 | DOI:10.1016/j.nefroe.2024.02.011 (Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia)
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - April 18, 2024 Category: Urology & Nephrology Authors: Melissa Rau Adrian Santelli Sara Mart í Mar ía Isabel Díaz Nuria Sab é Mar ía Fiol Luis Riera Bego ña Etcheverry Sergi Codina Ana Coloma Anna Carreras-Salinas Carmen Ardanuy Josep M Cruzado Edoardo Melilli Source Type: research

Challenges in the treatment of pediatric Mycoplasma pneumoniae pneumonia
Conclusion:  This report summarizes the clinical significance of macrolide-resistant and refractory MP pneumonia and discusses the efficacy and safety of alternative drugs, with a stepwise approach to the management of MP pneumonia recommended from the viewpoint of clinical practice.What is Known:•Although MP pneumonia is usually a benign self-limited infection with response macrolides as first line therapy,severe life-threatening cases may develop if additional treatment strategies are not effectively implemented.•Macrolide-resistant and refractory MP pneumonia are two conditions that may complicate the clinical cour...
Source: European Journal of Pediatrics - April 18, 2024 Category: Pediatrics Source Type: research

Occipital dermal sinus associated with infectious teratoma in an adult patient affected by Klippel-Feil syndrome: Rare case report and literature review
CONCLUSION: The association between KFS, cerebellar teratoma, and DS has not yet been described in the literature, with only the association of the first two being extremely rare.PMID:38628535 | PMC:PMC11021108 | DOI:10.25259/SNI_1024_2023 (Source: Surgical Neurology International)
Source: Surgical Neurology International - April 17, 2024 Category: Neurosurgery Authors: Breno Nery Victoria Rodrigues Durand Rafael De Almeida Rabello Anna Carolyne Mendes De Oliveira Eduardo Quaggio Manoela Marques Ortega Bruno Camporezi Jos é Alencar De Sousa Segundo Source Type: research

Endoscopic closure techniques of bariatric surgery complications: a meta-analysis
ConclusionObservational reports show that patients managed with OTSC were more likely to experience healing of their defect than those managed with endoscopic suturing. Larger controlled studies comparing different closure devices for bariatric leaks should be carried out to better understand the ideal endoscopic approach to these complications. (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - April 17, 2024 Category: Surgery Source Type: research

Sepsis and case fatality rates and associations with deprivation, ethnicity, and clinical characteristics: population-based case –control study with linked primary care and hospital data in England
ConclusionGiven the variety of predictors and their level of associations for developing sepsis, there is a need for prediction models for risk of developing sepsis that can help to target preventative antibiotic therapy. (Source: Infection)
Source: Infection - April 16, 2024 Category: Infectious Diseases Source Type: research

Mycotic aortic aneurysms: characteristic macroscopic findings in a case series
We report 10 patients with MAAs in whom macroscopically, similar coined-sized lesions of the inner aortic wall were seen in all cases. When a coin-sized lesion in the inner aortic wall is seen during open surgical repair of an aortic aneurysm, the surgeon should consider an infectious cause. Microbiological tissue samples should be collected, and additional targeted antibiotic therapy should be started.PMID:38616531 | DOI:10.1080/14017431.2024.2341696 (Source: Scandinavian Cardiovascular Journal)
Source: Scandinavian Cardiovascular Journal - April 15, 2024 Category: Cardiology Authors: Tim Somers Hedwig M J M Nies Ilse J E Kouijzer Pui Yuen Lee Wim J Morshuis Guillaume S C Geuzebroek Source Type: research