Evaluation of the Antimicrobial, Cytotoxic, and Physical Properties of Selected Nano-Complexes in Bovine Udder Inflammatory Pathogen Control
CONCLUSION: Synergistic effects of nanoparticles and no toxicity to bovine and human cells might, in the future, be an effective alternative in the fight against microorganisms responsible for mastitis, and the implementation of research results in practice would reduce the percentage of dairy cows suffering from mastitis. The problem of increasing antibiotic resistance is posing a global threat to human's and animal's health, and requires comprehensive research to evaluate the potential use of nanoparticles - especially their complexes - as well as to determine whether nanoparticles are safe for the breeders and the anima...
Source: Appl Human Sci - March 25, 2024 Category: Physiology Authors: Mateusz Wierzbicki Magdalena Kot Agata Lange Aleksandra Kali ńska Marcin Go łębiewski S ławomir Jaworski Source Type: research
Evaluation of the Antimicrobial, Cytotoxic, and Physical Properties of Selected Nano-Complexes in Bovine Udder Inflammatory Pathogen Control
CONCLUSION: Synergistic effects of nanoparticles and no toxicity to bovine and human cells might, in the future, be an effective alternative in the fight against microorganisms responsible for mastitis, and the implementation of research results in practice would reduce the percentage of dairy cows suffering from mastitis. The problem of increasing antibiotic resistance is posing a global threat to human's and animal's health, and requires comprehensive research to evaluate the potential use of nanoparticles - especially their complexes - as well as to determine whether nanoparticles are safe for the breeders and the anima...
Source: Appl Human Sci - March 25, 2024 Category: Physiology Authors: Mateusz Wierzbicki Magdalena Kot Agata Lange Aleksandra Kali ńska Marcin Go łębiewski S ławomir Jaworski Source Type: research
Evaluation of the Antimicrobial, Cytotoxic, and Physical Properties of Selected Nano-Complexes in Bovine Udder Inflammatory Pathogen Control
CONCLUSION: Synergistic effects of nanoparticles and no toxicity to bovine and human cells might, in the future, be an effective alternative in the fight against microorganisms responsible for mastitis, and the implementation of research results in practice would reduce the percentage of dairy cows suffering from mastitis. The problem of increasing antibiotic resistance is posing a global threat to human's and animal's health, and requires comprehensive research to evaluate the potential use of nanoparticles - especially their complexes - as well as to determine whether nanoparticles are safe for the breeders and the anima...
Source: Appl Human Sci - March 25, 2024 Category: Physiology Authors: Mateusz Wierzbicki Magdalena Kot Agata Lange Aleksandra Kali ńska Marcin Go łębiewski S ławomir Jaworski Source Type: research
Evaluation of the Antimicrobial, Cytotoxic, and Physical Properties of Selected Nano-Complexes in Bovine Udder Inflammatory Pathogen Control
CONCLUSION: Synergistic effects of nanoparticles and no toxicity to bovine and human cells might, in the future, be an effective alternative in the fight against microorganisms responsible for mastitis, and the implementation of research results in practice would reduce the percentage of dairy cows suffering from mastitis. The problem of increasing antibiotic resistance is posing a global threat to human's and animal's health, and requires comprehensive research to evaluate the potential use of nanoparticles - especially their complexes - as well as to determine whether nanoparticles are safe for the breeders and the anima...
Source: Appl Human Sci - March 25, 2024 Category: Physiology Authors: Mateusz Wierzbicki Magdalena Kot Agata Lange Aleksandra Kali ńska Marcin Go łębiewski S ławomir Jaworski Source Type: research
Evaluation of the Antimicrobial, Cytotoxic, and Physical Properties of Selected Nano-Complexes in Bovine Udder Inflammatory Pathogen Control
CONCLUSION: Synergistic effects of nanoparticles and no toxicity to bovine and human cells might, in the future, be an effective alternative in the fight against microorganisms responsible for mastitis, and the implementation of research results in practice would reduce the percentage of dairy cows suffering from mastitis. The problem of increasing antibiotic resistance is posing a global threat to human's and animal's health, and requires comprehensive research to evaluate the potential use of nanoparticles - especially their complexes - as well as to determine whether nanoparticles are safe for the breeders and the anima...
Source: Appl Human Sci - March 25, 2024 Category: Physiology Authors: Mateusz Wierzbicki Magdalena Kot Agata Lange Aleksandra Kali ńska Marcin Go łębiewski S ławomir Jaworski Source Type: research
Evaluation of the Antimicrobial, Cytotoxic, and Physical Properties of Selected Nano-Complexes in Bovine Udder Inflammatory Pathogen Control
CONCLUSION: Synergistic effects of nanoparticles and no toxicity to bovine and human cells might, in the future, be an effective alternative in the fight against microorganisms responsible for mastitis, and the implementation of research results in practice would reduce the percentage of dairy cows suffering from mastitis. The problem of increasing antibiotic resistance is posing a global threat to human's and animal's health, and requires comprehensive research to evaluate the potential use of nanoparticles - especially their complexes - as well as to determine whether nanoparticles are safe for the breeders and the anima...
Source: Appl Human Sci - March 25, 2024 Category: Physiology Authors: Mateusz Wierzbicki Magdalena Kot Agata Lange Aleksandra Kali ńska Marcin Go łębiewski S ławomir Jaworski Source Type: research
1,25 DIHYDROXYVITAMIN D < sub > 3 < /sub > -MEDIATED EFFECTS ON BOVINE INNATE IMMUNITY AND ON BIOFILM-FORMING Staphylococcus spp. ISOLATED FROM CATTLE WITH MASTITIS
This study tested the effects of active vitamin D3 (i.e., calcitriol or 1,25-dihydroxyvitamin D3) on the internalization and phagocytosis of biofilm-forming Staphylococcus spp. isolated from animals with mastitis. Two established bovine cell lines were used: MAC-T (mammary epithelial cells) and BoMac (macrophages). Calcitriol (0-200nM) did not affect the viability of MAC-T cells nor that of BoMac cells after 24 and 72h. Concentrations of 0-100mM for 24h upregulated the expression of 24-hydroxylase in MAC-T cells, but did not alter that of VDR. Pre-treatment of the cells with calcitriol for 24h decreased the internalization...
Source: Mol Biol Cell - March 23, 2024 Category: Molecular Biology Authors: Georgina Tiraboschi Paula Isaac Mar ía Laura Breser Virginia Angiolini Luc ía Rodriguez-Berdini Carina Porporatto Luciana Paola Bohl Source Type: research
Hungatella hathewayi bacteremia due to acute appendicitis: A case report and a narrative review
This article presents the case of an 87-year-old Asian male admitted for a hyperosmolar hyperglycemic state with septic shock secondary to Hungatella hathewayi bacteremia originating from acute appendicitis. Remarkably, the bacterium was detected in the blood 48 hours before the emergence of clinical and radiographic evidence of acute appendicitis. Additionally, we conducted a literature review to identify all documented human infections caused by Hungatella species. Timely microbial identification in such cases is essential for implementing targeted antibiotic therapy and optimizing clinical outcomes.PMID:38521228 | DOI:1...
Source: Anaerobe - March 23, 2024 Category: Microbiology Authors: Elie Bou Sanayeh Mark Tawfik Marina Makram Georges Khattar Faris Qaqish Sudeep Acharya Janet Farag Michel Chalhoub Allison Glaser Source Type: research
Hungatella hathewayi bacteremia due to acute appendicitis: A case report and a narrative review
This article presents the case of an 87-year-old Asian male admitted for a hyperosmolar hyperglycemic state with septic shock secondary to Hungatella hathewayi bacteremia originating from acute appendicitis. Remarkably, the bacterium was detected in the blood 48 hours before the emergence of clinical and radiographic evidence of acute appendicitis. Additionally, we conducted a literature review to identify all documented human infections caused by Hungatella species. Timely microbial identification in such cases is essential for implementing targeted antibiotic therapy and optimizing clinical outcomes.PMID:38521228 | DOI:1...
Source: Anaerobe - March 23, 2024 Category: Microbiology Authors: Elie Bou Sanayeh Mark Tawfik Marina Makram Georges Khattar Faris Qaqish Sudeep Acharya Janet Farag Michel Chalhoub Allison Glaser Source Type: research
1,25 DIHYDROXYVITAMIN D < sub > 3 < /sub > -MEDIATED EFFECTS ON BOVINE INNATE IMMUNITY AND ON BIOFILM-FORMING Staphylococcus spp. ISOLATED FROM CATTLE WITH MASTITIS
This study tested the effects of active vitamin D3 (i.e., calcitriol or 1,25-dihydroxyvitamin D3) on the internalization and phagocytosis of biofilm-forming Staphylococcus spp. isolated from animals with mastitis. Two established bovine cell lines were used: MAC-T (mammary epithelial cells) and BoMac (macrophages). Calcitriol (0-200nM) did not affect the viability of MAC-T cells nor that of BoMac cells after 24 and 72h. Concentrations of 0-100mM for 24h upregulated the expression of 24-hydroxylase in MAC-T cells, but did not alter that of VDR. Pre-treatment of the cells with calcitriol for 24h decreased the internalization...
Source: Mol Biol Cell - March 23, 2024 Category: Molecular Biology Authors: Georgina Tiraboschi Paula Isaac Mar ía Laura Breser Virginia Angiolini Luc ía Rodriguez-Berdini Carina Porporatto Luciana Paola Bohl Source Type: research
Hungatella hathewayi bacteremia due to acute appendicitis: A case report and a narrative review
This article presents the case of an 87-year-old Asian male admitted for a hyperosmolar hyperglycemic state with septic shock secondary to Hungatella hathewayi bacteremia originating from acute appendicitis. Remarkably, the bacterium was detected in the blood 48 hours before the emergence of clinical and radiographic evidence of acute appendicitis. Additionally, we conducted a literature review to identify all documented human infections caused by Hungatella species. Timely microbial identification in such cases is essential for implementing targeted antibiotic therapy and optimizing clinical outcomes.PMID:38521228 | DOI:1...
Source: Anaerobe - March 23, 2024 Category: Microbiology Authors: Elie Bou Sanayeh Mark Tawfik Marina Makram Georges Khattar Faris Qaqish Sudeep Acharya Janet Farag Michel Chalhoub Allison Glaser Source Type: research
Incidence and outcomes of postoperative fluid collections after minimally invasive distal pancreatectomy without placement of surgical drain. A prospective observational cohort study
ConclusionsPatients who undergo MIDP without surgical drain placement develop well-tolerated pancreatic collections. Although a minority may require endoscopic or percutaneous drainage, the majority can be managed conservatively and resolve spontaneously in the long term. (Source: Journal of Hepato-Biliary-Pancreatic Surgery)
Source: Journal of Hepato-Biliary-Pancreatic Surgery - March 23, 2024 Category: Surgery Authors: N úria Lluís,
Filipe Kunzler,
Domenech Asbun,
Ramon E. Jimenez,
Horacio J. Asbun Tags: ORIGINAL ARTICLE Source Type: research
The effect of thyme essential oil and endothelial progenitor stem cells on lipopolysaccharide ‐induced sepsis in C57BL/6 mice
AbstractSepsis is a potentially fatal syndrome related to severe systemic inflammation developed by infection. Despite different antimicrobial therapies, morbidity and mortality rates remain high. Herbs along with cell therapy have been introduced as a promising option to improve the symptoms of sepsis. The present study aimed to evaluate the therapeutic effect of simultaneous administration of thyme essential oil (TEO) and endothelial progenitor stem cells (EPCs) on lipopolysaccharide (LPS)-induced sepsis in C57BL/6 mice. Sepsis was induced in C57Bl/6J mice by intraperitoneal injection of LPS, followed 2 h later by an i...
Source: Biotechnology and Applied Biochemistry - March 22, 2024 Category: Biochemistry Authors: Mohammad Mehdi Soltan Dallal,
Maryam Siavashi,
Samira Karimaei,
Vahid Siavashi,
Milad Abdi,
Mehdi Yaseri,
Seyed Alireza Razavi,
Ronak Bakhtiari Tags: ORIGINAL ARTICLE Source Type: research
Assessing the potential for improved predictive capacity of antimicrobial resistance in outpatient Staphylococcus aureus isolates using seasonal and spatial antibiograms
ConclusionsStandard antibiograms are poor in predictingS. aureus susceptibility to antibiotics often chosen by clinicians, and seasonal and spatial antibiograms do not provide an improved tool in anticipating non-susceptibility. These findings suggest that further refinements to antibiograms may be necessary to improve their utility in informing choice of effective antibiotic therapy. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - March 22, 2024 Category: Infectious Diseases Source Type: research
