Emerging threats of high biofilm formation and antibiotic resistance in clinical methicillin-resistant Staphylococcus aureus (MRSA) isolates from Pakistan
CONCLUSIONS: Clinical MRSA strains exhibit a substantial potential for biofilm formation, contributing to a resistant phenotype. Routine antibiotic testing in clinical settings that overlook the biofilm aspect may lead to the failure of empiric antibiotic therapy.PMID:38614413 | DOI:10.1016/j.meegid.2024.105592 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - April 13, 2024 Category: Genetics & Stem Cells Authors: Asad Ali Saba Riaz Source Type: research
Emerging threats of high biofilm formation and antibiotic resistance in clinical methicillin-resistant Staphylococcus aureus (MRSA) isolates from Pakistan
CONCLUSIONS: Clinical MRSA strains exhibit a substantial potential for biofilm formation, contributing to a resistant phenotype. Routine antibiotic testing in clinical settings that overlook the biofilm aspect may lead to the failure of empiric antibiotic therapy.PMID:38614413 | DOI:10.1016/j.meegid.2024.105592 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - April 13, 2024 Category: Genetics & Stem Cells Authors: Asad Ali Saba Riaz Source Type: research
Intramyocardial abscess and endoventricular thrombosis: a complex case
We describe the complex case of a 57-year-old patient, presented in ED for fever and oleocranical bursitis, increase of cardiac enymes at blood samples. He was admitted to our Cardiology Unit because TTE showed a floating peduncolated formation in the left ventricle. The susequent TEE documented also the presence of a myocardial abscess, confirmed at cardiac MRI. Blood cultures were positive for MSSA and the man received specific antibiotic therapy. Anticoagulation treatment was started with UFH and then switched to Warfarin, surgical approach of the lesion would have been too dangerous according to Cardiac Surgeons. Serio...
Source: The International Journal of Cardiovascular Imaging - April 13, 2024 Category: Radiology Source Type: research
Infectious Aspects of Chronic Wounds
This article will discuss the pathophysiology of infection in older adults, including specific infections such as cutaneous candidiasis, necrotizing soft tissue infection, osteomyelitis, and infections involving hardware. (Source: Clinics in Geriatric Medicine)
Source: Clinics in Geriatric Medicine - April 12, 2024 Category: Geriatrics Authors: Natalie E. Nierenberg, Jeffrey M. Levine Source Type: research
Potential role of Citrus bergamia flower essential oil against oral pathogens
Oral bacterial infections are difficult to treat due to emergence of resistance against antibiotic therapy. Essential oils are considered emerging alternate therapy against bacterial infections and biofilms. W... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - April 12, 2024 Category: Complementary Medicine Authors: Muhammad Imran Aziz, Muhammad Mohtasheemul Hasan, Riaz Ullah, Ahmed Bari, Mohsin Abbas Khan, Syed Zia Ul Hasnain, Rabia Baloch, Muhammad Akram, Aqsa obaid, Aziz Ullah, Khizar Abbas and Adnan Amin Tags: Research Source Type: research
Difficult-to-treat (DTR) < em > Pseudomonas aeruginosa < /em > harboring Verona-Integron metallo- β-lactamase ( < em > bla < /em > < sub > VIM < /sub > ): infection management and molecular analysis
This study was conducted in a large academic healthcare system in Miami, FL, between December 2018 and January 2022. Patients were prospectively identified via rapid molecular diagnostics when cultures revealed carbapenem-resistant P. aeruginosa. Alerts were received in real time by the antimicrobial stewardship program and infection prevention teams. Upon alert recognition, a series of interventions were performed as a coordinated effort. A retrospective chart review was conducted to collect patient demographics, antimicrobial therapy, and clinical outcomes. Thirty-nine VIM-CRPA isolates led to infection in 21 patients. T...
Source: Antimicrobial Agents and Chemotherapy - April 11, 2024 Category: Microbiology Authors: Ana D Vega Kailynn DeRonde Adriana Jimenez Michael Piazza Christine Vu Octavio Martinez Laura J Rojas Steven Marshall Mohamad Yasmin Robert A Bonomo Lilian M Abbo Source Type: research
Difficult-to-treat (DTR) < em > Pseudomonas aeruginosa < /em > harboring Verona-Integron metallo- β-lactamase ( < em > bla < /em > < sub > VIM < /sub > ): infection management and molecular analysis
This study was conducted in a large academic healthcare system in Miami, FL, between December 2018 and January 2022. Patients were prospectively identified via rapid molecular diagnostics when cultures revealed carbapenem-resistant P. aeruginosa. Alerts were received in real time by the antimicrobial stewardship program and infection prevention teams. Upon alert recognition, a series of interventions were performed as a coordinated effort. A retrospective chart review was conducted to collect patient demographics, antimicrobial therapy, and clinical outcomes. Thirty-nine VIM-CRPA isolates led to infection in 21 patients. T...
Source: Antimicrobial Agents and Chemotherapy - April 11, 2024 Category: Microbiology Authors: Ana D Vega Kailynn DeRonde Adriana Jimenez Michael Piazza Christine Vu Octavio Martinez Laura J Rojas Steven Marshall Mohamad Yasmin Robert A Bonomo Lilian M Abbo Source Type: research
Bartonella quintana pulmonary native valve endocarditis
AbstractBartonella quintana is a well-known cause of blood culture-negative endocarditis; however, pulmonary valve involvement is rare. The case of a 40-year-old African male who presented to the Emergency Department with chest pain, cardiac failure, and a 2-week history of fever is presented. Transoesophageal echocardiography confirmed an atrial septal defect, severe pulmonary insufficiency with large vegetations, severe mitral regurgitation due to anterior leaflet prolapse, and right ventricular dysfunction. Empirical antibiotic therapy was started, and urgent surgical intervention was decided. There were vegetations on ...
Source: Indian Journal of Thoracic and Cardiovascular Surgery - April 10, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research
Identification of pathogen composition in a Chinese population with iatrogenic and native vertebral osteomyelitis by using mNGS
CONCLUSION: The results of this study hold promise in providing valuable guidance to clinical practitioners for the differential diagnosis and early antimicrobial treatment of vertebral osteomyelitis.PMID:38590185 | DOI:10.1080/07853890.2024.2337738 (Source: Annals of Medicine)
Source: Annals of Medicine - April 9, 2024 Category: Internal Medicine Authors: Qile Gao Qianfei Liu Guang Zhang Yingqing Lu Yanbing Li Mingxing Tang Shaohua Liu Hongqi Zhang Xiaojiang Hu Source Type: research
Systemic and Bilateral Severe Ocular Toxoplasmosis Resembling Autoimmune Phenomena: A Case Report
CONCLUSION AND IMPORTANCE: This case underscores the importance of ruling out an infectious etiology in all cases of uveitis. Additionally, it alerts clinicians to the possibility that elevated positive autoantibodies may result from a severe inflammatory reaction caused by pathogens rather than an autoimmune or autoinflammatory disease, particularly in instances of poor treatment response or atypical clinical presentation.PMID:38592492 | DOI:10.1080/09273948.2024.2336605 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 9, 2024 Category: Allergy & Immunology Authors: Sofia Romero-Santos Daniela Parra-Tanoux Carlos Cifuentes-Gonz ález Juliana Mu ñoz-Ortiz Germ án Mejía-Salgado Alejandra de-la-Torre Source Type: research
Identification of pathogen composition in a Chinese population with iatrogenic and native vertebral osteomyelitis by using mNGS
CONCLUSION: The results of this study hold promise in providing valuable guidance to clinical practitioners for the differential diagnosis and early antimicrobial treatment of vertebral osteomyelitis.PMID:38590185 | DOI:10.1080/07853890.2024.2337738 (Source: Annals of Medicine)
Source: Annals of Medicine - April 9, 2024 Category: Internal Medicine Authors: Qile Gao Qianfei Liu Guang Zhang Yingqing Lu Yanbing Li Mingxing Tang Shaohua Liu Hongqi Zhang Xiaojiang Hu Source Type: research
Emmert's plastic surgery
Oper Orthop Traumatol. 2024 Apr 9. doi: 10.1007/s00064-024-00843-z. Online ahead of print.ABSTRACTOBJECTIVE: The aim of the surgical intervention is the elimination of infections, ulceration and pain caused by ingrown nails (unguis incarnatus).INDICATIONS: A surgical intervention is recommended for ingrown nails (the large toenail is most frequently affected) in stage III and higher (according to the Mozena classification) as well as in cases of nail plate defects and recurrences.CONTRAINDICATIONS: In cases where a disturbance of wound healing is expected and general contraindications for surgery.SURGICAL TECHNIQUE: The su...
Source: Operative Orthopadie und Traumatologie - April 9, 2024 Category: Orthopaedics Authors: Abdullah Tarwnah Marlon De la Cruz Mohammad Tezval Source Type: research
Systemic and Bilateral Severe Ocular Toxoplasmosis Resembling Autoimmune Phenomena: A Case Report
CONCLUSION AND IMPORTANCE: This case underscores the importance of ruling out an infectious etiology in all cases of uveitis. Additionally, it alerts clinicians to the possibility that elevated positive autoantibodies may result from a severe inflammatory reaction caused by pathogens rather than an autoimmune or autoinflammatory disease, particularly in instances of poor treatment response or atypical clinical presentation.PMID:38592492 | DOI:10.1080/09273948.2024.2336605 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - April 9, 2024 Category: Allergy & Immunology Authors: Sofia Romero-Santos Daniela Parra-Tanoux Carlos Cifuentes-Gonz ález Juliana Mu ñoz-Ortiz Germ án Mejía-Salgado Alejandra de-la-Torre Source Type: research
Emmert's plastic surgery
Oper Orthop Traumatol. 2024 Apr 9. doi: 10.1007/s00064-024-00843-z. Online ahead of print.ABSTRACTOBJECTIVE: The aim of the surgical intervention is the elimination of infections, ulceration and pain caused by ingrown nails (unguis incarnatus).INDICATIONS: A surgical intervention is recommended for ingrown nails (the large toenail is most frequently affected) in stage III and higher (according to the Mozena classification) as well as in cases of nail plate defects and recurrences.CONTRAINDICATIONS: In cases where a disturbance of wound healing is expected and general contraindications for surgery.SURGICAL TECHNIQUE: The su...
Source: Operative Orthopadie und Traumatologie - April 9, 2024 Category: Orthopaedics Authors: Abdullah Tarwnah Marlon De la Cruz Mohammad Tezval Source Type: research
Emmert's plastic surgery
Oper Orthop Traumatol. 2024 Apr;36(2):125-131. doi: 10.1007/s00064-024-00843-z. Epub 2024 Apr 9.ABSTRACTOBJECTIVE: The aim of the surgical intervention is the elimination of infections, ulceration and pain caused by ingrown nails (unguis incarnatus).INDICATIONS: A surgical intervention is recommended for ingrown nails (the large toenail is most frequently affected) in stage III and higher (according to the Mozena classification) as well as in cases of nail plate defects and recurrences.CONTRAINDICATIONS: In cases where a disturbance of wound healing is expected and general contraindications for surgery.SURGICAL TECHNIQUE: ...
Source: Operative Orthopadie und Traumatologie - April 9, 2024 Category: Orthopaedics Authors: Abdullah Tarwnah Marlon De la Cruz Mohammad Tezval Source Type: research
