Hairy leukoplakia in a patient undergoing anti-retroviral therapy
We report a case of hairy leukoplakia that developed in a patient undergoing anti-retroviral therapy. A 53-year old white male presented with mild erythema in the anterior maxillary gingiva and was managed with clobetasol gel, after excluding the possibility of candidiasis. Patient's medical history was significant for HIV, bipolar disorder, high blood pressure, high cholesterol, chronic bronchitis, smoking, and alcohol. His medications included Androgel, Axiron, atorvastatin, bupropion, clonazepam, finasteride, hydrochlorothiazide, lamotrigine, lisinopril, pantoprazole, Prezcobix, Trazadone, Truvada (200 mg emticitabine, ...
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - June 13, 2019 Category: ENT & OMF Source Type: research
Hairy leukoplakia in a patient undergoing anti-retroviral therapy
We report a case of hairy leukoplakia that developed in a patient undergoing anti-retroviral therapy. A 53-year old white male presented with mild erythema in the anterior maxillary gingiva and was managed with clobetasol gel, after excluding the possibility of candidiasis. Patient's medical history was significant for HIV, bipolar disorder, high blood pressure, high cholesterol, chronic bronchitis, smoking, and alcohol. His medications included Androgel, Axiron, atorvastatin, bupropion, clonazepam, finasteride, hydrochlorothiazide, lamotrigine, lisinopril, pantoprazole, Prezcobix, Trazadone, Truvada (200 mg emticitabine, ...
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - June 13, 2019 Category: ENT & OMF Authors: Dr. Kelcie Barnts, Dr. Celeste Abraham, Dr. Yi-Shing Lisa Cheng Tags: #124 Source Type: research
Correction to: Pharmacokinetics and Bioavailability of a New Testosterone Gel Formulation in Comparison to Testogel ® in Healthy Men
Clinical Pharmacology in Drug Development, EarlyView. (Source: Clinical Pharmacology in Drug Development)
Source: Clinical Pharmacology in Drug Development - June 11, 2019 Category: Drugs & Pharmacology Tags: Correction Source Type: research
Preferences for the administration of testosterone gel: evidence from a discrete choice experiment
(Source: Patient Preference and Adherence)
Source: Patient Preference and Adherence - April 30, 2019 Category: International Medicine & Public Health Tags: Patient Preference and Adherence Source Type: research
Combined nestorone –testosterone gel suppresses serum gonadotropins to concentrations associated with effective hormonal contraception in men
ConclusionDaily Nes ‐T gel effectively and safely suppresses serum gonadotropins and is acceptable to most men. It should be studied further in efficacy trials of hormonal male contraception. (Source: Andrology)
Source: Andrology - April 9, 2019 Category: Urology & Nephrology Authors: B. D. Anawalt,
M. Y. Roth,
J. Ceponis,
V. Surampudi,
J. K. Amory,
R. S. Swerdloff,
P. Y. Liu,
C. Dart,
W. J. Bremner,
R. Sitruk ‐Ware,
N. Kumar,
D. L. Blithe,
S. T. Page,
C. Wang Tags: Original Article Source Type: research
Efficacy of oral estrogen plus testosterone gel to improve sexual function in postmenopausal women.
CONCLUSION: The addition of low-dose testosterone gel to daily estrogen may improve sexual function in postmenopausal women, but further evaluation and safety data are needed.
PMID: 30810382 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - February 27, 2019 Category: Geriatrics Authors: Chaikittisilpa S, Soimongkol K, Jaisamrarn U Tags: Climacteric Source Type: research
Premature Pubarche due to Exogenous Testosterone Gel or Intense Diaper Rash Prevention Cream Use: A Case Series
Conclusion: Unintentional topical androgen exposure or the intense use of diaper rash prevention cream should be ruled out in children with precocious pubarche and/or virilization signs to avoid misdiagnosis and expendable investigation.Horm Res Paediatr (Source: Hormone Research in Paediatrics)
Source: Hormone Research in Paediatrics - January 27, 2019 Category: Endocrinology Source Type: research
Male Contraceptive Development: Update on Novel Hormonal and Nonhormonal Methods [Reviews]
BACKGROUND:
Development of new methods of male contraception would address an unmet need for men to control their fertility and could increase contraceptive options for women. Pharmaceutical research and development for male contraception was active in the 1990s but has been virtually abandoned. The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) has supported a contraceptive development program since 1969 and supports the majority of hormonal male contraceptive development. Nonhormonal methods are also in development but are at earlier stages.
CONTENT:
Several hormonal male contrac...
Source: Clinical Chemistry - January 2, 2019 Category: Chemistry Authors: Long, J. E., Lee, M. S., Blithe, D. L. Tags: Other Areas of Clinical Chemistry Reviews Source Type: research
Effect of testosterone replacement on measures of mobility in older men with mobility limitation and low testosterone concentrations: secondary analyses of the Testosterone Trials
Publication date: November 2018Source: The Lancet Diabetes & Endocrinology, Volume 6, Issue 11Author(s): Shalender Bhasin, Susan S Ellenberg, Thomas W Storer, Shehzad Basaria, Marco Pahor, Alisa J Stephens-Shields, Jane A Cauley, Kristine E Ensrud, John T Farrar, David Cella, Alvin M Matsumoto, Glenn R Cunningham, Ronald S Swerdloff, Christina Wang, Cora E Lewis, Mark E Molitch, Elizabeth Barrett-Connor, Jill P Crandall, Xiaoling Hou, Peter PrestonSummaryBackgroundThe Physical Function Trial (PFT) was one of seven Testosterone Trials (TTrials), the aim of which was to assess the effect of testosterone on mobility, self-rep...
Source: The Lancet Diabetes and Endocrinology - October 24, 2018 Category: Endocrinology Source Type: research
Effects of natesto ® on reproductive hormones and semen parameters: a prospective clinical trial
We present preliminary results from our ongoing prospective clinical trial. (Source: Fertility and Sterility)
Source: Fertility and Sterility - September 1, 2018 Category: Reproduction Medicine Authors: T. Masterson, M. Molina, D.M. Lopategui, E. Ibrahim, R. Ramasamy Tags: Poster session Source Type: research
Transfer of Topical Testosterone to Subcutaneous Microdialysate, Blood and Saliva in Healthy Young Men
Conclusion Single topical administration of testosterone gel leads to a continuous increase of testosterone in the subcutaneous ipsilateral microdialysate. Rapid salivary testosterone increase happens after gel administration followed by tenfold increased testosterone plateau values. Despite continuous influx, testosterone concentrations in serum, saliva, and contralateral microdialysate show a plateau formation thus avoiding testosterone excess. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - August 8, 2018 Category: Endocrinology Authors: Krebs, Andreas Clement, Hans-Willi Zimmerer, Jutta Schulz, Eberhard Doerfer, J ürgen Wurm, Michael Brichta, Corinna van der Werf-Grohmann, Natascha Schwab, Karl Otfried Tags: Article Source Type: research
Long-Term Testosterone Supplementation in Older Men Attenuates Age-Related Decline in Aerobic Capacity.
Conclusion: The mean 3-year change in V˙O2peak was significantly less in testosterone-treated men than in men receiving placebo and was associated with increases in hemoglobin. The difference in V˙O2peak change between groups may indicate attenuation of its expected age-related decline; the clinical meaningfulness of the modest treatment effect remains to be determined.
PMID: 29846604 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - May 25, 2018 Category: Endocrinology Authors: Traustadóttir T, Harman SM, Tsitouras P, Pencina KM, Li Z, Travison TG, Eder R, Miciek R, McKinnon J, Woodbury E, Basaria S, Bhasin S, Storer TW Tags: J Clin Endocrinol Metab Source Type: research
A new 2% testosterone gel formulation: a comparison with currently available topical preparations
Andrology,Volume 6, Issue 3, Page 396-407, May 2018. (Source: Andrology)
Source: Andrology - March 30, 2018 Category: Urology & Nephrology Authors: S. Arver
,
C. Stief
,
J. de la Rosette
,
T. H. Jones
,
A. Neijber
,
D. Carrara Source Type: research
Effects of short ‐term sex steroid suppression on dietary fat storage patterns in healthy males
Abstract
Hypogonadism in males is associated with increased body fat and altered postprandial metabolism, but mechanisms remain poorly understood. Using a cross‐over study design, we investigated the effects of short‐term sex hormone suppression with or without testosterone add‐back on postprandial metabolism and the fate of dietary fat. Eleven healthy males (age: 29 ± 4.5 year; BMI: 26.3 ± 2.1 kg/m2) completed two 7‐day study phases during which hormone levels were altered pharmacologically to produce a low sex hormone condition (gonadotropin releasing hormone antagonist, aromatase inhibitor, and placebo g...
Source: Physiological Reports - January 22, 2018 Category: Physiology Authors: Corey A. Rynders, Stacy L. Schmidt, Audrey Bergouignan, Tracy J. Horton, Daniel H. Bessesen Tags: Original Research Source Type: research
