Hairy leukoplakia in a patient undergoing anti-retroviral therapy
We report a case of hairy leukoplakia that developed in a patient undergoing anti-retroviral therapy. A 53-year old white male presented with mild erythema in the anterior maxillary gingiva and was managed with clobetasol gel, after excluding the possibility of candidiasis. Patient's medical history was significant for HIV, bipolar disorder, high blood pressure, high cholesterol, chronic bronchitis, smoking, and alcohol. His medications included Androgel, Axiron, atorvastatin, bupropion, clonazepam, finasteride, hydrochlorothiazide, lamotrigine, lisinopril, pantoprazole, Prezcobix, Trazadone, Truvada (200 mg emticitabine, 300 mg tenofovir), Ziprasidone, zolpidem, and baby aspirin. During one of multiple follow-up appointments, an asymptomatic white plaque was identified on right lateral tongue. Clinical differential diagnoses included hairy leukoplakia and hyperkeratosis secondary to trauma. Patient reported that his physician changed Truvada to Descovy (200 mg emticitabine, 25 mg tenofovir) since his last appointment. At the appointment six weeks later, the white plaque increased in size, and additional white plaques were found on the left dorso-lateral surface and dorsal tongue.Two biopsies were taken, one from the right lateral and the other from left dorso-lateral tongue. The biopsies showed similar histological features including hyperparakeratosis with shaggy surface and bacterial colonization. Intracellular edema and pyknotic nuclei were noted in the spinous cell layer...
Publication date: Available online 16 July 2019Source: The Egyptian RheumatologistAuthor(s): Amany R. El-Najjar, ahmed A. elsammakAbstractAim of the workTo study the effects of serum homocysteine (Hcy) on arterial wall properties, as a contributing risk factor for arterial atherosclerosis and thrombosis.Patients and methodsFifty Behçet's disease (BD) patients (M/F:37/13; age:34.8 ± 8.5 years) along with 50 healthy controls (M/F:32/18; age:31.9 ± 8.1 years) matched for age, sex, blood pressure, heart rate, height, total cholesterol and glucose levels were included. All were recruited Zagazig...
Conclusion: Our meta-analysis results revealed higher cardiovascular risk in OA patients. This highlights the importance of cardiovascular risk factor management in OA.
HIGH blood pressure can lead to serious and even life-threatening health conditions if left untreated, so doing what you can to prevent a high reading is very important. Studies have shown the following three supplements to lower high blood pressure readings.
ConclusionOverall, it seems that given its ease of measurement, the WC index is preferred to other indices for predicting the incidence of MetS and its components in clinical screening.
ConclusionsEarly stakeholder identification and engagement using the International Association of Public Participation model eased explanation of research objectives, building consensus, and shaping the interventions to improve the referral process.
ConclusionsMultiple strategies, based on implementation principles, are required for successful scaling up of research-based interventions.
ConclusionsWe identified lessons learned, challenges, and opportunities during the adaptation process. Findings will inform ongoing stakeholder engagement during the study implementation and future scale-up and efforts to translate evidence-based hypertension control strategies to low- and middle-income countries globally.
ConclusionsMultiple layers of stakeholders and communities in Vietnam are fully engaged with, and have contributed significantly to, our ongoing hypertension control research project in Northern Vietnam.
Publication date: June 2019Source: Global Heart, Volume 14, Issue 2Author(s): Ana A. Baumann, Vincent Mutabazi, Angela L. Brown, Cole Hooley, Dominic Reeds, Cecile Ingabire, Vedaste Ndahindwa, Aurore Nishimwe, W. Todd Cade, Lisa de las Fuentes, Enola K. Proctor, Stephen Karengera, Kenneth B. Schecthman, Charles W. Goss, Kevin Yarasheski, Brad Newsome, Eugene Mutimura, Victor G. Davila-RomanAbstractBackgroundCardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide and in low- and middle-income countries, and hypertension (HTN) is a major risk factor for CVD. Although effective evidence-based in...
ConclusionsThe majority of CHOs in this study were aware of lifestyle modifications such as diet modifications and increase in physical activity. However, their knowledge was limited in the blood pressure threshold for initiating treatment and in the knowledge of first-line hypertension medication, irrespective of the number of years practiced. Training on hypertension is also low. However, CHOs are motivated to control hypertension at the community level. Community-level interventions such as TASSH can leverage on their motivation to demonstrate an impact on hypertension control.
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