Hairy leukoplakia in a patient undergoing anti-retroviral therapy

We report a case of hairy leukoplakia that developed in a patient undergoing anti-retroviral therapy. A 53-year old white male presented with mild erythema in the anterior maxillary gingiva and was managed with clobetasol gel, after excluding the possibility of candidiasis. Patient's medical history was significant for HIV, bipolar disorder, high blood pressure, high cholesterol, chronic bronchitis, smoking, and alcohol. His medications included Androgel, Axiron, atorvastatin, bupropion, clonazepam, finasteride, hydrochlorothiazide, lamotrigine, lisinopril, pantoprazole, Prezcobix, Trazadone, Truvada (200 mg emticitabine, 300 mg tenofovir), Ziprasidone, zolpidem, and baby aspirin.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Tags: #124 Source Type: research

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Authors: Johansson V, Erhardt S, Engberg G, Kegel M, Bhat M, Schwieler L, Blennow K, Zetterberg H, Cannon TD, Wetterberg L, Hultman CM, Landén M Abstract Preclinical studies indicate a link between the kynurenine pathway and monocyte chemoattractant protein-1 (MCP-1), but there is a lack of clinical studies examining this further. We here perform a secondary analysis of kynurenine metabolites and MCP-1 in cerebrospinal fluid of 23 twins affected from schizophrenia, bipolar disorder or unaffected. We show an association between MCP-1 and kynurenic acid (KYNA), driven by unique environmental influences and a l...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
Authors: Barton BB, Zagler A, Engl K, Rihs L, Musil R Abstract The information on prevalence of obesity, diabetes, metabolic syndrome (MetS) and cardiovascular risk (CVR) and on sociodemographic variables available in patients with psychiatric diseases about to be treated with weight gain-associated medication (e.g., clozapine, mirtazapine, quetiapine) is limited. In a naturalistic study, psychiatric inpatients (age: 18-75) of all F diagnoses according to ICD-10, who were about to be treated with weight gain-associated medication, were included. Demographic variables were assessed as well as biological parameters t...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
CONCLUSIONS: BPD was found in 15% of adolescents and they have higher proportion of BED and BSD. Early identification may help in planning early intervention strategies to reduce associated morbidity. PMID: 31302438 [PubMed - as supplied by publisher]
Source: Asian Journal of Psychiatry - Category: Psychiatry Tags: Asian J Psychiatr Source Type: research
In this study, we showed that a serum lipoprotein(a) level>40.5 mg/dL in a mildly preeclamptic patient predicted the development of severe preeclampsia later on in the pregnancy, whereas a serum lipoprotein(a) level>52.5 mg/dL was a marker of severity with high sensitivity and specificity. What the implications are of these findings for clinical practice and/or further research? Our results suggest that blood lipids, and especially lipoprotein(a), are involved in the pathogenesis of preeclampsia. The lipoprotein(a) level correlates with the severity of the disease. Hence, lipoprotein(a) could be used as...
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
In this study, we engineered Y. lipolytica to produce FAEEs from dextrose as well as from vegetable cooking oil as a model food waste. Firstly, we introduced pyruvate decarboxylase (pdc) and alcohol dehydrogenase II (adhB) from Zymomonas mobilis to reconstitute the heterologous pathway for ethanol production. Second, we introduced and compared two heterologous wax ester synthases ws2 and maqu_0168 from Marinobacter sp. for FAEE biosynthesis. Next, we disrupted competitive pathways to increase fatty acyl-CoA pool, and optimized carbon sources and cell density for shake-flask fermentation. The engineered strain showed a...
Source: Journal of Bioscience and Bioengineering - Category: Biomedical Science Source Type: research
Publication date: Available online 15 July 2019Source: Journal of Bioscience and BioengineeringAuthor(s): Takuya Matsumoto, Yuki Mori, Tsutomu Tanaka, Akihiko KondoBioamination methods using microorganisms have attracted much attention because of the increasing demand for environmentally friendly bioprocesses. n-Butylamine production from glucose in Escherichia coli was demonstrated in this study, which has never been reported because of the absence of n-butylamine-producing pathway in nature. We focused on a transaminase-mediated cascade for bioamination from an alcohol or aldehyde. The cascade can convert an alcohol or a...
Source: Journal of Bioscience and Bioengineering - Category: Biomedical Science Source Type: research
This study assessed changes in the endocrine function of the renin-angiotensin-aldosterone system (RAAS) and steroid hormone production (steroidogenesis) in juvenile alligators exposed to brackish water (12‰) for 7 days. We quantified plasma levels of angiotensin II and the corticosteroids (aldosterone, corticosterone and 11-deoxycortisol). Various progestogens, androgens, and estrogens were further assessed. The protein expression for the RAAS enzymes, renin and angiotensin converting enzyme (ACE), was quantified immunohistochemically in kidney and lung tissue, respectively, and histology was performed on kidney,...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - Category: Biochemistry Source Type: research
Publication date: Available online 15 July 2019Source: The Journal of Chemical ThermodynamicsAuthor(s): A. Vicent Orchillés, Ernesto Vercher, Pablo J. Miguel, Vicenta González-Alfaro, Francisco J. LlopisAbstractIsobaric vapor–liquid equilibria for the binary systems tert-butyl alcohol + water, and tert-butyl alcohol + 1-ethyl-3-methylimidazolium dicyanamide ([emim][DCA]), as well as the vapor–liquid equilibria for the tert-butyl alcohol + water + [emim][DCA] ternary system, have been obtained at 100 kPa using a recirculating still. The electrolyte nonrandom two-liquid (e-NRTL) model was successful...
Source: The Journal of Chemical Thermodynamics - Category: Chemistry Source Type: research
New J. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9NJ02407G, PaperZhifang Wu, Yunling Li, Jun Li, Mengwei Wang, Zhifei Wang Mixtures of anionic surfactant fatty alcohol ether carboxylate ester (A12-14EC9E-Na) and cationic surfactant bis-decylmethylhydroxyethylammonium chloride (DEQ) were studied systematically. Comparing with single systems (A12-14EC9E-Na or DEQ), mixed system (A12-14EC9E-Na/DEQ) exhibits... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - Category: Chemistry Authors: Source Type: research
Analyst, 2019, Accepted Manuscript DOI: 10.1039/C9AN01230C, PaperXiaoming Chen, Yukun Ren, Likai Hou, Xiangsong Feng, Tianyi Jiang, Hongyuan Jiang Five arc-shaped gaps were designed on the bipolar electrode to actuate alternately opposite-direction asymmetrical induced-charge electro-osmosis (AICEO) vortices, and we developed a microfluidic device using such asymmetrical vortices to realize... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
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