Molecular Aspects of Mucoepidermoid Carcinoma and Adenoid Cystic Carcinoma of the Salivary Gland
ConclusionsMolecular analysis is essential not only to improve the diagnosis and prognosis of the tumors but also to identify novel driver pathways in the precision medicine scenario. (Source: Head and Neck Pathology)
Source: Head and Neck Pathology - April 24, 2024 Category: Pathology Source Type: research
Reply to Kalfert comment on “Zwierz et al. Maximal medical treatment of adenoid hypertrophy: a prospective study of preschool children”
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 23, 2024 Category: ENT & OMF Source Type: research
Comment on and correction of Zwierz et al. Maximal medical treatment of adenoid hypertrophy: a prospective study of preschool children
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 23, 2024 Category: ENT & OMF Source Type: research
The Median Effective Dose of Dexmedetomidine for the Inhibition of Emergence Delirium in Preschool Children Undergoing Tonsillectomy and/or Adenoidectomy: A Retrospective Dose-response Trial
Dose Response. 2024 Apr 19;22(2):15593258241248919. doi: 10.1177/15593258241248919. eCollection 2024 Apr-Jun.ABSTRACTThe incidence of emergence delirium (ED) is higher in preschool children undergoing tonsillectomy and/or adenoidectomy. The purpose of this study was to determine the median effective dose (ED50) of dexmedetomidine (DEX) for the inhibition of ED in preschool children by using probit regression analysis. A total of 140 anesthesia records were retrieved and divided into seven groups based on the infusion rate of DEX: .2, .25, .3, .35, .4, .45, and .5 μg·kg-1·h-1. The Pediatric Anesthesia Emergence Delirium ...
Source: Dose Response - April 22, 2024 Category: Drugs & Pharmacology Authors: BaiYun Wei CuiYu Yu JinBo Xiao Huang Xu Ping Zheng WeiBing Wang Source Type: research
The Median Effective Dose of Dexmedetomidine for the Inhibition of Emergence Delirium in Preschool Children Undergoing Tonsillectomy and/or Adenoidectomy: A Retrospective Dose-response Trial
Dose Response. 2024 Apr 19;22(2):15593258241248919. doi: 10.1177/15593258241248919. eCollection 2024 Apr-Jun.ABSTRACTThe incidence of emergence delirium (ED) is higher in preschool children undergoing tonsillectomy and/or adenoidectomy. The purpose of this study was to determine the median effective dose (ED50) of dexmedetomidine (DEX) for the inhibition of ED in preschool children by using probit regression analysis. A total of 140 anesthesia records were retrieved and divided into seven groups based on the infusion rate of DEX: .2, .25, .3, .35, .4, .45, and .5 μg·kg-1·h-1. The Pediatric Anesthesia Emergence Delirium ...
Source: Dose Response - April 22, 2024 Category: Drugs & Pharmacology Authors: BaiYun Wei CuiYu Yu JinBo Xiao Huang Xu Ping Zheng WeiBing Wang Source Type: research
Molecules, Vol. 29, Pages 1901: Anti-Tumor Activity and Mechanism of Silibinin Based on Network Pharmacology and Experimental Verification
This study aimed to assess the anti-tumor effects of silibinin in adenoid cystic carcinoma (ACC2) cells and Balb/c nude mice, and explore its potential mechanism based on network pharmacology prediction and experimental verification. A total of 347 targets interacting with silibinin were collected, and 75 targets related to the tumor growth process for silibinin were filtrated. Based on the PPI analysis, CASP3, SRC, ESR1, JAK2, PRKACA, HSPA8 and CAT showed stronger interactions with other factors and may be the key targets of silibinin for treating tumors. The predicted target proteins according to network pharmacology wer...
Source: Molecules - April 22, 2024 Category: Chemistry Authors: Peihai Li Dexu Wang Xueliang Yang Changyu Liu Xiaobin Li Xuanming Zhang Kechun Liu Yun Zhang Mengqi Zhang Changyun Wang Rongchun Wang Tags: Article Source Type: research
Tympanoplasty can be Concurrent with Adenoidectomy. Tube Factor Assessment
AbstractTo assess changes in middle ear pressures following adenotonsillectomies in children, and to evaluate the possibility of performing tympanoplasty at the same surgical time. Prospective study in which tube function was assessed using tympanometry on the first postoperative day and on the seventh postoperative day after adenotonsillectomies. A total of 39 children aged 6.8 ± 2.6 years were evaluated. On the first postoperative day, 79.5% presented with changes in middle ear pressure. On the seventh postoperative day, only 12.8% maintained this change. Tube dysfunction following adenotonsillectomy is transient a...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 22, 2024 Category: ENT & OMF Source Type: research
Endotracheal enucleation and para ‐toluenesulfonamide injection for adenoid cystic carcinoma in the upper trachea: A novel therapeutic approach
We present a case of tracheal adenoid cystic carcinoma (ACC) treated with endotracheal enucleation followed by three doses of para-toluenesulfonamide (PTS)-lipiodol mixture injection. The treatment resulted in tumor eradication, improved airway patency, and absence of recurrence in 1 year, suggesting PTS as a promising alternative for inoperable ACC. AbstractWe present a case of an adenoid cystic carcinoma (ACC) located in the upper trachea, which resulted in significant airway blockage, that was unsuitable for surgical removal due to concerns about functional impairment. Instead, endotracheal enucleation via rigid bron...
Source: Thoracic Cancer - April 19, 2024 Category: Cancer & Oncology Authors: Hsiao ‐Hung Lu,
Shuenn‐Wen Kuo Tags: CASE REPORT Source Type: research
Imaging of salivary gland cancers derived from a sublingual gland herniated into the submandibular space: a report of three cases
AbstractSublingual gland herniation into the submandibular space through a mylohyoid muscle defect is a common anatomical variation; however, salivary gland cancers that arise from a herniated sublingual gland have not been described yet. Here, we report three patients with salivary gland cancers originating from a herniated sublingual gland. All tumors were detected as palpable submandibular masses, located anterior to the submandibular gland, medial to the mandible, and lateral to the mylohyoid muscle, with contact with the sublingual gland through a mylohyoid muscle defect. Intraoperative findings confirmed that the mas...
Source: Neuroradiology - April 19, 2024 Category: Radiology Source Type: research
Platinum-based adjuvant chemoradiotherapy versus adjuvant radiotherapy in patients with head and neck adenoid cystic carcinoma
CONCLUSION: In terms of reducing locoregional failures in HNACC patients, POCRT may potentially offer a more effective therapeutic approach than using PORT alone, although it also entails an augmented burden of treatment-related toxicity.PMID:38625410 | DOI:10.1007/s00432-024-05719-0 (Source: Cancer Control)
Source: Cancer Control - April 16, 2024 Category: Cancer & Oncology Authors: Zichen Qiu Zheng Wu Xiong Zhou Minchuan Lin Yong Su Yalan Tao Source Type: research
Platinum-based adjuvant chemoradiotherapy versus adjuvant radiotherapy in patients with head and neck adenoid cystic carcinoma
ConclusionIn terms of reducing locoregional failures in HNACC patients, POCRT may potentially offer a more effective therapeutic approach than using PORT alone, although it also entails an augmented burden of treatment-related toxicity. (Source: Journal of Cancer Research and Clinical Oncology)
Source: Journal of Cancer Research and Clinical Oncology - April 16, 2024 Category: Cancer & Oncology Source Type: research
Comparison of PAS and adenoids in patients with and without maxillary micrognathia before orthodontic treatment
ConclusionsSkeletal anomalies affect the dimension of the posterior airway space. There were differences among the subjects with maxillary micrognathia and these with a normal maxilla. However, the maxilla was only assessed in the sagittal direction, not in the transverse. This study showed that the morphology of the maxilla relates to the posterior airway space whereas the adenoids seem not to be affected.Clinical relevanceMaxillary micrognathia is significantly associated with a smaller depth of the posterior airway space at the palatal level compared to patients with maxillary eugnathia. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - April 16, 2024 Category: Dentistry Source Type: research
A Case of a Eustachian Tube Hairy Polyp Misdiagnosed as an Adenoid Residual in a Child
This article discusses a 12-year-old female who had a growth at the Eustachian tube's entrance on the left side of the nasopharyngeal wall, as identified by a computed tomography scan of the neck soft tissue; it was suspected to be a hairy polyp originating from the left Eustachian tube. The diagnosis of a hairy polyp was confirmed through pathology. The hairy polyp at the Eustachian tube, in this case, showed an irregular form with a wide base, making it look similar to an adenoid; thus, increasing the risk of it being misdiagnosed as residual adenoid tissue.PMID:38605528 | DOI:10.1177/01455613241244667 (Source: Ear, Nose and Throat Journal)
Source: Ear, Nose and Throat Journal - April 12, 2024 Category: ENT & OMF Authors: Yi Liu Tian Wen Yang Yi Lin Long Wen Bo Xu Li Wen Tang Chun Lei Li Source Type: research
A Case of a Eustachian Tube Hairy Polyp Misdiagnosed as an Adenoid Residual in a Child
This article discusses a 12-year-old female who had a growth at the Eustachian tube's entrance on the left side of the nasopharyngeal wall, as identified by a computed tomography scan of the neck soft tissue; it was suspected to be a hairy polyp originating from the left Eustachian tube. The diagnosis of a hairy polyp was confirmed through pathology. The hairy polyp at the Eustachian tube, in this case, showed an irregular form with a wide base, making it look similar to an adenoid; thus, increasing the risk of it being misdiagnosed as residual adenoid tissue.PMID:38605528 | DOI:10.1177/01455613241244667 (Source: Ear, Nose and Throat Journal)
Source: Ear, Nose and Throat Journal - April 12, 2024 Category: ENT & OMF Authors: Yi Liu Tian Wen Yang Yi Lin Long Wen Bo Xu Li Wen Tang Chun Lei Li Source Type: research
A Case of a Eustachian Tube Hairy Polyp Misdiagnosed as an Adenoid Residual in a Child
This article discusses a 12-year-old female who had a growth at the Eustachian tube's entrance on the left side of the nasopharyngeal wall, as identified by a computed tomography scan of the neck soft tissue; it was suspected to be a hairy polyp originating from the left Eustachian tube. The diagnosis of a hairy polyp was confirmed through pathology. The hairy polyp at the Eustachian tube, in this case, showed an irregular form with a wide base, making it look similar to an adenoid; thus, increasing the risk of it being misdiagnosed as residual adenoid tissue.PMID:38605528 | DOI:10.1177/01455613241244667 (Source: Ear, Nose and Throat Journal)
Source: Ear, Nose and Throat Journal - April 12, 2024 Category: ENT & OMF Authors: Yi Liu Tian Wen Yang Yi Lin Long Wen Bo Xu Li Wen Tang Chun Lei Li Source Type: research
