Clinical manifestations and genetic mutation analysis of patients with mucopolysaccharidosis type VII in China
CONCLUSION: The study's patients all presented with classic symptoms of MPS VII due to β-glucuronidase deficiency, with three new pathogenic mutations identified in the GUSB gene. Genetic counseling and prenatal testing were highlighted as crucial for disease prevention.PMID:38442846 | DOI:10.1016/j.ejmg.2024.104933 (Source: European Journal of Medical Genetics)
Source: European Journal of Medical Genetics - March 5, 2024 Category: Genetics & Stem Cells Authors: Xueying Su Xiaoyuan Zhao Xi Yin Li Liu Yonglan Huang Chunhua Zeng Xiuzhen Li Wen Zhang Source Type: research
Clinicopathological characteristics of patients with primary tracheal tumors: Analysis of eighty ‐nine cases
ConclusionHistological type plays a crucial role in the prognosis of primary tracheal tumors. ACC demonstrated a more favorable outcome compared with SCC. (Source: Thoracic Cancer)
Source: Thoracic Cancer - March 2, 2024 Category: Cancer & Oncology Authors: Aleksandra Pi órek,
Adam Płużański,
Paweł Teterycz,
Sylwia Tabor,
Kinga Winiarczyk,
Magdalena Knetki‐Wróblewska,
Dariusz M. Kowalski,
Maciej Krzakowski Tags: ORIGINAL ARTICLE Source Type: research
Increasing incidence of mastoidectomies in children : Result of reduced antibiotic therapy or late COVID-19 sequela?
CONCLUSION: No clear correlation with reduced outpatient antibiotic therapy could be found. Whether there exists an association with prior COVID infection cannot be judged at this time, due to the high number of asymptomatic and therefore unknown COVID infections.PMID:38429542 | DOI:10.1007/s00106-024-01435-w (Source: HNO)
Source: HNO - March 1, 2024 Category: ENT & OMF Authors: Thomas Gehrke Agmal Scherzad Source Type: research
HSP27 promotes vasculogenic mimicry formation in human salivary adenoid cystic carcinoma via the AKT-MMP-2/9 pathway
To explore the role and mechanism of heat shock protein 27 (HSP27) in SACC VM formation. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - March 1, 2024 Category: ENT & OMF Authors: Zhao-Yuan Xu, Jing Han, Kun Yang, Guan-Meng Zhang, Mai-Ning Jiao, Su-Xia Liang, Ying-Bin Yan, Wei Chen Source Type: research
Comment on and correction of Zwierz et al. Maximal medical treatment of adenoid hypertrophy: a prospective study of preschool children
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - March 1, 2024 Category: ENT & OMF Source Type: research
Regarding the risk factors for the emergence delirium in pediatric patients after tonsillectomy and adenoidectomy
(Source: Journal of Anesthesia)
Source: Journal of Anesthesia - March 1, 2024 Category: Anesthesiology Source Type: research
Molecular profiling and the impact of treatment on outcomes in adenoid cystic carcinoma (ACC) type-I and II
CONCLUSIONS: We confirmed the previously reported associations with MYC and TP63 in the prognostically relevant subgroups of ACC-I and II, respectively, and report immunologic differences among these subtypes. Survival outcomes are comparatively worse in ACC-I regardless of treatment type.PMID:38416410 | DOI:10.1158/1078-0432.CCR-23-3182 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - February 28, 2024 Category: Cancer & Oncology Authors: Glenn J Hanna Punita Grover Andrew Elliott Julie McGrath Joanne Xiu Ammar Sukari Jennifer M Johnson Trisha Wise-Draper Source Type: research
Molecular profiling and the impact of treatment on outcomes in adenoid cystic carcinoma (ACC) type-I and II
CONCLUSIONS: We confirmed the previously reported associations with MYC and TP63 in the prognostically relevant subgroups of ACC-I and II, respectively, and report immunologic differences among these subtypes. Survival outcomes are comparatively worse in ACC-I regardless of treatment type.PMID:38416410 | DOI:10.1158/1078-0432.CCR-23-3182 (Source: Cell Research)
Source: Cell Research - February 28, 2024 Category: Cytology Authors: Glenn J Hanna Punita Grover Andrew Elliott Julie McGrath Joanne Xiu Ammar Sukari Jennifer M Johnson Trisha Wise-Draper Source Type: research
Predictors of Success of Adenoidectomy in the Treatment of Pediatric Chronic Rhinosinusitis
Conclusions: Adenoidectomy is a good first-line surgery for children aged 12 years and younger, especially in the 6 to 12 years group which had a high rate of success with 68% experiencing remission of symptoms after surgery.PMID:38400707 | DOI:10.1177/01455613241232879 (Source: Ear, Nose and Throat Journal)
Source: Ear, Nose and Throat Journal - February 24, 2024 Category: ENT & OMF Authors: Amani Kais Norman Orabi Ruifeng Cui Hassan H Ramadan Source Type: research
Predictors of Success of Adenoidectomy in the Treatment of Pediatric Chronic Rhinosinusitis
Conclusions: Adenoidectomy is a good first-line surgery for children aged 12 years and younger, especially in the 6 to 12 years group which had a high rate of success with 68% experiencing remission of symptoms after surgery.PMID:38400707 | DOI:10.1177/01455613241232879 (Source: Ear, Nose and Throat Journal)
Source: Ear, Nose and Throat Journal - February 24, 2024 Category: ENT & OMF Authors: Amani Kais Norman Orabi Ruifeng Cui Hassan H Ramadan Source Type: research
Dose-averaged LET optimized carbon-ion radiotherapy for head and neck cancers
Carbon-ion radiotherapy (CIRT) is expected to be effective in treating tumors that are resistant to radiation therapy because of its excellent dose concentration and strong biological effects due to high linear energy transfer (LET) radiation. In the head and neck region, most reports of effective CIRT have been for non-squamous cell carcinomas. According to a Japanese multicenter study on CIRT, the 5-year overall survival (OS) and 5-year local control (LC) of 289 patients with adenoid cystic carcinoma were 74 % and 68 %, respectively [1]. (Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - February 23, 2024 Category: Radiology Authors: Masashi Koto, Hiroaki Ikawa, Taku Inaniwa, Reiko Imai, Makoto Shinoto, Hirotoshi Takiyama, Tetsuro Isozaki, Hideyuki Mizuno, Ryosuke Kohno, Ikumi Takahashi, Naoki Yoshida, Shigeru Yamada Tags: Short Communication Source Type: research
Evaluation of EGFR in prognostic characterization in histopathological variants of oral squamous cell carcinoma
CONCLUSION: Expression of EGFR could be established as a valuable biomarker with significant association in predicting aggressive potential and treatment response in various histopathological variants of OSCC. Further studies where EGFR could be linked to predictive indicators and tumor prognosis could be undertaken.PMID:38384049 | DOI:10.4103/jcrt.jcrt_1317_22 (Source: Cell Research)
Source: Cell Research - February 22, 2024 Category: Cytology Authors: Deepanshu Tyagi Meenakshi Singhal Nikita Gulati Anshi Jain Devi Charan Shetty Source Type: research
Illness and (hyper)masculinity in 'HIMM comics from the USA
In this essay, I analyse HIMM comics from the USA, a specific textualisation of graphic medicine/pathography that deals with a variety of illness experiences by male cartoonists. It is my contention that, in the existing literature, the motif of masculinity in autobiographical health-related comics is an underdeveloped area of academic enquiry. As a result, my analysis focuses on how three North American men depict ill health in their work in relation to existing sociological understandings of male behaviour. The texts I discuss are John Porcellino’s The Hospital Suite (2014), a story about his abdominal tumour; Matt...
Source: Medical Humanities - February 22, 2024 Category: International Medicine & Public Health Authors: Mitchell, P. Tags: Open access Original research Source Type: research
