Dose-averaged LET optimized carbon-ion radiotherapy for head and neck cancers

Carbon-ion radiotherapy (CIRT) is expected to be effective in treating tumors that are resistant to radiation therapy because of its excellent dose concentration and strong biological effects due to high linear energy transfer (LET) radiation. In the head and neck region, most reports of effective CIRT have been for non-squamous cell carcinomas. According to a Japanese multicenter study on CIRT, the 5-year overall survival (OS) and 5-year local control (LC) of 289 patients with adenoid cystic carcinoma were 74  % and 68 %, respectively [1].

Source: Radiotherapy and Oncology - February 23, 2024 Category: Radiology Authors: Masashi Koto, Hiroaki Ikawa, Taku Inaniwa, Reiko Imai, Makoto Shinoto, Hirotoshi Takiyama, Tetsuro Isozaki, Hideyuki Mizuno, Ryosuke Kohno, Ikumi Takahashi, Naoki Yoshida, Shigeru Yamada Tags: Short Communication Source Type: research