[Medical examination: Preparation for ENT specialization : Part  50].
[Medical examination: Preparation for ENT specialization : Part 50]. HNO. 2020 Sep 17;: Authors: Eichhorn T PMID: 32940770 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - September 19, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Tumor microenvironment in salivary gland carcinomas: Consequences for new therapeutic concepts].
CONCLUSIONS: LAG3 is particularly detectable in aggressive entities and advanced tumors. Hence, LAG3 inhibition poses a potential targeted therapy for advanced and metastatic SGCs. PMID: 32929519 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - September 18, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Epistaxis and anticoagulation therapy: an analysis based on health insurance data from Lower Saxony].
CONCLUSION: In addition to arterial hypertension, the predominant male sex and the typical age distribution, we found that cases of epistaxis often received anticoagulation therapy. This study showed an increase of epistaxis along with rising prescriptions of NOAC. In contrast, no increase of severe epistaxis cases leading to hospitalization was found. PMID: 32929520 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - September 18, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Functional outcome after transmandibular resection and primary chemoradiation in advanced oropharyngeal squamous cell carcinoma].
Authors: Knopf A, Mansour N, Hofauer B, Johnson F, Bier H, Wakonig F, Teutsch S Abstract OBJECTIVE: The aim of this study was to assess the functional outcome after transmandibular resection and reconstruction via a radial forearm flap (TMR+RFF) compared to primary chemoradiotherapy (pCRT) in advanced oropharyngeal squamous cell carcinoma (OPSCC). METHODS: The study compared 50 OPSCC patients treated with TMR+RFF to 50 OPSCC patients receiving pCRT. The time taken to swallow water served as the primary endpoint. The Saxon test, maxillomandibular distance, Mallampati score, ratio of height to weig...
Source: HNO - September 18, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Plastic reconstructive surgery in patients with oropharyngeal tumors].
Authors: Remmert S, Hasenberg S Abstract Oropharyngeal tumors can cause severe dysfunctions, which are often worsened by surgical and/or radiotherapy. The severity and type of dysfunction depends on the extent and localization of the resection. In general, entire organ resections lead to greater impairment than partial resections, whereas extended partial resection often equates to total resection. Plastic reconstructive surgery can help to preserve and reconstruct specific functions. Herein, the various surgical techniques with different flaps and tissue grafts are described, and the indications are presented depe...
Source: HNO - September 18, 2020 Category: ENT & OMF Tags: HNO Source Type: research

["Online from tomorrow on please": comparison of digital framework conditions of curricular teaching at national university ENT clinics in times of COVID-19 : Digital teaching at national university ENT clinics].
CONCLUSION: There are positive examples of successful transformation of classroom teaching to an exclusively virtual summer semester 2020 within the university ENT clinics; however, critical ratings of assistant professors and medical directors regarding the current teaching situation predominated. A time-critical strategic advancement is urgently needed. PMID: 32929523 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - September 18, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Impact of CI use and CI fitting on speech production in very early cochlear-implanted infants].
CONCLUSION: Very early cochlear implanted infants may achieve age-appropriate speech production performance in the third year of life. Time of daily CI use in the study cohort is comparable to results of other studies. Time of daily CI use and exposure to speech seem to be important factors for early speech production. These findings should be integrated in pre- and postoperative parent counselling. PMID: 32930827 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - September 18, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Neutrophils in the tumor microenvironment-foes or friends?]
Authors: Jablonska J, Rist M, Lang S, Brandau S Abstract Neutrophils are the most abundant white blood cells in the human circulation and are usually associated with inflammation and with fighting infections. In recent years, the role of these cells during cancer progression has been a matter of increasing interest. Tumor-associated neutrophils (TANs) accumulate in cancer patients and represent an important negative prognostic marker in a broad variety of neoplasms. Accordingly, TANs represent a highly attractive therapeutic target. TAN may exhibit tumor-promoting or -inhibiting functions. Pro-tumor ...
Source: HNO - September 12, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Robot-assisted head and neck surgery].
Authors: Schuler PJ, Boehm F, Schild LR, Greve J, Hoffmann TK Abstract Robot-assisted surgery (RAS) has already been approved for several clinical applications in head and neck surgery. In some Anglo-American regions, RAS is currently the common standard for treatment of oropharyngeal diseases. Systematic randomized studies comparing established surgical procedures with RAS in a large number of patients are unavailable so far. Experimental publications rather describe how to reach poorly accessible anatomical regions using RAS, or represent feasibility studies on the use of transoral robotic surgery (TORS) in ...
Source: HNO - September 12, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[From reconstruction to function : Hands-on training in tympanoplasty using real-time feedback].
CONCLUSION: Training on suitable models is indispensable, especially when training as a surgeon to carry out middle ear operations. Adding another sense perception to the internal and external quality assessment of tympanoplasty by inclusion of the real-time feedback option, can optimize learning and operating processes. PMID: 32910259 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - September 12, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Conservative treatment of obstructive sleep apnea using non-PAP therapies].
Authors: Maurer JT, Leitzbach S Abstract In Germany about one third of adults aged between 30 and 69 years suffer from obstructive sleep apnea (OSA). Snoring, inspiratory flow limitations, hypopneas, and apneas occur, leading to disturbed sleep, reduced daytime performance, and increased cardiovascular morbidity and mortality. Positive airway pressure therapy (PAP therapy) can be successfully administered in every OSA severity. However, other conservative treatments have to be considered for some patients, particularly in PAP failure or intolerance. The individual treatment concept is based on poly(somno)graph...
Source: HNO - September 9, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Multimodal training concept for temporal bone surgery].
CONCLUSION: The curriculum integrates different training models of mastoidectomy and OSATS into an overall concept. The training plan has to be continuously adapted to new findings and technical developments. PMID: 32885307 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - September 5, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Differential diagnosis of hypersomnia in surgical sleep medicine-more than just sleep apnea!]
Authors: Stuck BA, Weeß HG, Viniol C, Cassel W, Birk R Abstract Otorhinolaryngologists play a vital role in the management of patients with obstructive sleep apnea (OSA) in Germany, particularly with regards to outpatient diagnostics as well as conservative and surgical treatment of patients with intolerance to ventilation therapy. Although establishment of differential indications for surgical therapy and performance of additional preoperative drug-induced sleep endoscopy in patients with sleep-disordered breathing are among the core competencies of otorhinolaryngologists, differential diagnostic consid...
Source: HNO - September 5, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[The diagnostic course : A  new form of teaching in otorhinolaryngology education].
CONCLUSION: The advantages of our diagnostic course are the opportunity to apply practical skills and the small group sizes (maximum five students). The discipline of otorhinolaryngology and its varied character could be optimally presented in this manner. Disadvantageous are the high personnel and logistic requirements, which should, however, be met during university teaching. PMID: 32885309 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - September 5, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Evaluation of standardized questionnaires for diagnosis and differentiation of obstructive and patulous Eustachian tube dysfunction].
CONCLUSION: The PHI-10 and ETDQ‑7 (German) can be recommended as an additional tool for preoperative assessment of ET dysfunction. However, they insufficiently discriminate between patulous and obstructive ET dysfunction and are not suitable for patients with tinnitus. The strength of the two questionnaires lies in their suitability for use in monitoring therapeutic success during follow-up. PMID: 32885310 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - September 5, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Management of transmodiolar and transmacular cochleovestibular schwannomas with and without cochlear implantation. German version].
CONCLUSIONS: Cochleovestibular schwannomas with transmodiolar and transmacular extension represent a rare entity with specific management requirements. Hearing rehabilitation with CI is a principal option in these patients. PMID: 32886128 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - September 5, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Young female patient with bony frontotemporal swelling].
Authors: Gey A, Weinert K, Kunze C, Plontke SK PMID: 32886129 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - September 5, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Nonexudative pharyngitis with intermittent fever].
Authors: Büchel AS, Jungehülsing M PMID: 32886130 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - September 5, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[A  cervical inflammation and signs of sepsis].
[A cervical inflammation and signs of sepsis]. HNO. 2020 Sep 02;: Authors: Kühn JP, Vogt T, Schick B PMID: 32876718 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - September 4, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Quality of cochlear implant rehabilitation under COVID-19 conditions. German version].
CONCLUSION: The implementation of the new hygiene modalities within the therapeutic rehabilitation setting was well-accepted by patients allowing access to auditory rehabilitation. A successful rehabilitation should ensure a fear-free environment by adhering to the necessary hygiene modalities. PMID: 32876719 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - September 4, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Clinical oncology-new developments].
Authors: Lang S PMID: 32856099 [PubMed - in process] (Source: HNO)
Source: HNO - August 30, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[New ways in hearing rehabilitation after cochlear implantation].
CONCLUSION: The train2hear platform represents a first prototype of a computer-based auditory rehabilitation program in German. Further evaluation and development in a clinical study are needed to determine the feasibility and efficacy of the platform. PMID: 32856120 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - August 30, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Surgical reconstruction in laryngeal carcinoma].
Authors: Arens C, Schwemmle C, Voigt-Zimmermann S Abstract Tumors of the larynx can substantially impair vocal function, breathing and also swallowing. The primary goal of reconstructive surgical treatment of laryngeal tumors is to sufficiently resect the tumor while minimizing the effects of the treatment on the voice, breathing and swallowing. In general, primary reconstructions in primary laryngeal surgery have many advantages. The tissue at this point in time is soft because the scarring process has not yet been initiated. A better prerequisite for a sufficient glottic closure can also be expected thr...
Source: HNO - August 26, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Elective tracheostomy in COVID-19 patients: experience with a standardized interdisciplinary approach].
Authors: Pudszuhn A, Voegeler S, Berger C, Treskatsch S, Angermair S, Hansen S, Hofmann VM Abstract Experience with an interdisciplinary SOP (standard operating procedure) for tracheostomy (TS) in COVID-19 patients, taking into account the general national and international recommendations, is reported. The operative timing of TS due to prolonged invasive ventilation and frustrating weaning attempts was determined on an interdisciplinary level and involved phases of both high and low disease activity. Five TS were performed in patients with an average age of 70.6 years. In addition to the standard COVID-19 protecti...
Source: HNO - August 26, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Results of surgical and radiotherapeutic treatment of adenoid cystic carcinoma of the salivary glands].
In this study the overall survival and recurrence-free survival in 52 individuals with salivary gland ACC who were treated at the University Hospital in Essen and received irradiation with fast neutrons and photons (mixed beam technique) either A) immediately following surgical treatment or B) only after the appearance of local recurrence were compared. Group A (n = 28, first diagnosis, FD September 1991-September 2009) received adjuvant radiotherapy immediately postoperative, group B (n = 24, FD June 1979-November 2001) underwent primarily surgical tumor resection according to the treatmen...
Source: HNO - August 23, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Guideline on diagnosis, treatment, and follow-up of laryngeal cancer].
Authors: Bootz F Abstract The German S3 guideline on diagnosis, treatment, and follow-up of laryngeal cancer was developed in 2019 as part of the oncology guideline program of the Association of the Scientific Medical Societies in Germany (Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften, AWMF) of the German Cancer Society (Deutsche Krebsgesellschaft, DKG) and German Cancer Aid (Deutsche Krebshilfe, DKH), published under the leadership of the German Society for Otorhinolaryngology, Head and Neck Surgery. The guideline was funded by DKH as part of the oncology guideline program. Since guid...
Source: HNO - August 15, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Effective diagnostics for vertigo, dizziness and equilibrium disorders].
Authors: Schmäl F Abstract Vertigo, dizziness and equilibrium disorders are symptoms with a variety of causes. First, four cardinal questions (type and duration of the vertigo, triggering factors, accompanying symptoms) must be answered. After that, the search for a spontaneous nystagmus (differentiation of peripheral and central disorder using the HINTS[head impulse, nystagmus, test of skew]-test ) and, as part of a positioning examination, the search for a benign paroxysmal positional vertigo (BPPV) are necessary. If the result is negative an instrument-based receptor-specific examination...
Source: HNO - August 15, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Transoral resection of supraglottic laryngeal tumors with the Flex Robotic System].
In conclusion, supraglottic tumors in difficult-to-reach areas have been successfully resected using the Flex Robotic System, with excellent local tumor control. PMID: 32767027 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - August 13, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Surgical therapy of oropharyngeal cancer-state of the art].
Authors: Bootz F, Franzen A Abstract Surgical therapy, regardless of the procedure, remains of great importance for today's treatment of oropharyngeal carcinomas, despite advances in radiation and immunotherapy. The individual treatment plan should be defined in discussion with the patient and in an interdisciplinary tumor conference, taking into account the likelihood of achieving of tumor-free resection margins and an acceptable postoperative quality of life. With regard to conventional and possibly also open surgical procedures, a good overview of the surgical site-particularly in the case of more extensive...
Source: HNO - August 13, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Proton therapy-a chance in the treatment of tumors of the head and neck and base of skull].
This article presents an overview of current indications for PT with emphasis on tumors in the head and neck region and the base of skull. Furthermore, a summary and discussion of relevant results and current developments are included. MATERIALS AND METHODS: The work comprises an evaluation of relevant studies and an overview of current issues related to PT of tumors in the areas of the head, neck, and base of skull. RESULTS: Overall, the studies on PT show promising results. In addition to dosimetric studies, clinical studies also point to advantages of PT, especially with regard to the reduction of side effects. ...
Source: HNO - August 13, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Does sealing the oval window in addition to the round window bring an advantage in reserve therapy of acute idiopathic deafness?]
CONCLUSION: Additional sealing of the OW did not lead to significantly better postoperative hearing thresholds. In general, postoperative hearing improvement corresponds to published spontaneous remission rates. PMID: 32728759 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - August 1, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Primary cutaneous CD4+ small to medium-sized T-cell lymphoma in an adolescent patient].
Authors: Stähr K, Lang S, Mattheis S Abstract A rare finding of primary cutaneous CD4+ small to medium-sized T‑cell lymphoma (SMPTCL) in a fifteen-year-old patient is reported. This is a rare tumor entity for which there is currently no standardized treatment recommendation. At the interdisciplinary tumor board, the decision was made to resect the tumor and reconstruct the defect with a nasolabial advancement flap in a two-stage process. Follow-up examinations, currently over 3 years, have shown the patient to be free of recurrences. PMID: 32728760 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - August 1, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[The maxillary sinus-often in focus, individual, with many options].
Authors: Weber R PMID: 32728782 [PubMed - in process] (Source: HNO)
Source: HNO - August 1, 2020 Category: ENT & OMF Tags: HNO Source Type: research

Implantation of a  new active bone conduction hearing device with optimized geometry.
Implantation of a new active bone conduction hearing device with optimized geometry. HNO. 2020 Jul 28;: Authors: Plontke SK, Götze G, Wenzel C, Rahne T, Mlynski R Abstract Here, we describe the surgical technique for implanting a new, active, transcutaneous bone conduction hearing aid. The implant technology is based on a system that has been in use reliably since 2012. The geometry of the new implant has been adapted based on experience with previously introduced implants. The surgery was feasible, standardized, and safe. Due to the optimized geometric design that improved the bone fit, it i...
Source: HNO - July 30, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Tracheostoma valves and their associated risks].
Authors: Kress P, Pfeiffer K Abstract Tracheostoma valves have proven to be very effective for voice restoration in patients with a tracheotomy or laryngectomy. Nevertheless, in recent years there have been a number of reports about life-threatening incidents with tracheostoma valves. An analysis of these incidents and the commercially available tracheostoma valves, their functions and limitations enables typical risk situations to be derived. The most reported incidents were caused by inadvertently filling the cuff of the tracheostomy tube while the tracheostoma valve was in place and by confusing a heat and moist...
Source: HNO - July 23, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Effective noise dose as a  risk measure for noise-induced hearing loss].
[Effective noise dose as a risk measure for noise-induced hearing loss]. HNO. 2020 Jul 09;: Authors: Michel O PMID: 32647959 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - July 12, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Computer-based auditory training for hearing rehabilitation of adult cochlear implant users].
CONCLUSION: CBAT programs might be an effective option for auditory rehabilitation in CI patients. However, suitable German-language programs conceived as an alternative to face-to-face training and studies on longterm effects of CBAT are still lacking. PMID: 32647960 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - July 12, 2020 Category: ENT & OMF Tags: HNO Source Type: research

Development of a  smartphone app for neuromuscular facial training.
CONCLUSION: App-based facial training offers attractive opportunities to motivate patients for improved adherence to treatment, which could hypothetically lead to a better outcome. Evaluation of this question is planned in a clinical trial after completion of the development. PMID: 32638059 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - July 10, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[The role of surgery and salvage surgery in the era of HPV-associated oropharyngeal carcinomas].
Authors: Hussain T, Mattheis S, Lang S Abstract The incidence of human papillomavirus (HPV)-positive oropharyngeal carcinomas is increasing worldwide. Due to a markedly different response to treatment compared to HPV-negative oropharyngeal carcinomas, determining the ideal therapeutic approach can be challenging. Particularly in never-smokers, HPV-positive oropharyngeal carcinomas respond well to primary radiation therapy; at the same time recent studies indicate comparable survival after primary surgery. For stage I tumors according to TNM‑8, retrospective analyses show very good oncologic outcomes aft...
Source: HNO - July 10, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Suspected rare manifestation of a  thyroglossal and lateral cervical cyst-a diagnostic and therapeutic approach].
[Suspected rare manifestation of a thyroglossal and lateral cervical cyst-a diagnostic and therapeutic approach]. HNO. 2020 Jul 03;: Authors: Karal A, Capraro J, Metternich F, Müller M Abstract A 34-year-old female patient presented to our department with a 1.5 cm midline cystic lesion of the neck. A second cystic mass was found in level 2 of the left lateral neck. Following complete resection, histopathological examination revealed the diagnosis of a dystopic papillary thyroid carcinoma. Total thyroidectomy and bilateral neck dissection were performed. The pat...
Source: HNO - July 7, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Necrotizing fasciitis in the head and neck region-three case reports and a  review of the literature].
[Necrotizing fasciitis in the head and neck region-three case reports and a review of the literature]. HNO. 2020 Jul 02;: Authors: Huber L, Budjan J, Rotter N, Lammert A Abstract Necrotizing fasciitis (NF) is a life-threatening, usually bacterial, soft tissue infection that rarely affects the head and neck region. Rapid progression and systemic illness are typical for the disease and complicate diagnosis. Immediate surgical and antimicrobial therapy is required. Three cases of cervicofacial NF are presented in this case report. All patients showed a rapidly progressing, painful swelling ...
Source: HNO - July 4, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Non-healing wound of the facial skin].
Authors: Metzger K, Weißinger C, Hoffmann J PMID: 32613322 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - July 3, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Prognostic and predictive methylation biomarkers in HNSCC : Epigenomic diagnostics for head and neck squamous cell carcinoma (HNSCC)].
CONCLUSION: DNA methylation is a source of efficient prognostic blood plasma- and tissue-based biomarkers. However, prior to clinical implementation, studies must prove that biomarker-guided treatment selection can lead to better outcomes or reduced toxicity. The applicability of DNA methylation as a predictive biomarker for targeted drug-based cancer therapy seems promising, although further validation is needed. PMID: 32613323 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - July 3, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Medical examination: preparation for ENT specialisation : Part  49].
[Medical examination: preparation for ENT specialisation : Part 49]. HNO. 2020 Jun 29;: Authors: Lailach S, Neudert M PMID: 32601910 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - July 2, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Rare diseases of the maxillary sinus].
CONCLUSION: Medical history combined with endoscopic and radiologic criteria should improve preoperative diagnosis of these three rare diseases of the maxillary sinus and help to distinguish them from other differential diagnoses. This approach should minimize morbidity for the patients. PMID: 32583063 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - June 27, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Palliative care in otorhinolaryngology : It's quality of life that counts].
Authors: Dlugaiczyk J, Labbé D PMID: 32588081 [PubMed - in process] (Source: HNO)
Source: HNO - June 27, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Erratum to: Recognition function for the Freiburg monosyllabic test in noise with a signal to noise ratio (SNR) of 5dB].
Authors: Guy S, Schönweiler R, Wollenberg B, Zehlicke T, Pohl M, Löhler J PMID: 32556467 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - June 20, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[Unilateral diseases of the maxillary sinus].
Authors: Giotakis E, Knipping S, Kühnel T, Weber RK Abstract Unilateral diseases of the maxillary sinus are among the most common rhinologic diagnoses. The diversity of these diseases can represent a challenge for the treating physician. The spectrum ranges from harmless maxillary sinus cysts that seldom require treatment, to highly aggressive malignant tumors. Special attention should be given to the management of inverted papilloma. These benign tumors are characterized by high recurrence rates and the potential for malignant transformation. The key to minimizing recurrence is precise surgical intervent...
Source: HNO - June 20, 2020 Category: ENT & OMF Tags: HNO Source Type: research

Evidence-based diagnostic use of  VEMPs : From neurophysiological principles to clinical application.
CONCLUSION: The use of VEMPs is a simple, safe, reliable and selective test of dynamic function of otolith organs. PMID: 32533211 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - June 14, 2020 Category: ENT & OMF Tags: HNO Source Type: research

[FGFR-targeted therapy in head and neck carcinomas].
CONCLUSION: Early clinical and preclinical data point to the promise of biomarker-directed treatment of patients with head and neck tumors using FGFR-targeted TKIs. PMID: 32519203 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - June 12, 2020 Category: ENT & OMF Tags: HNO Source Type: research