Intermittent tinnitus-an empirical description.
CONCLUSION: IT is associated with emotional reactions and situational impairment severe enough to trigger multiple treatment attempts, but usually does not result in severe impairment. Inner ear disorders and psychological changes are less frequent than in CT; therefore, treatment response and prognosis might be better. We suggest classification of tinnitus into acute single-episode (3 months) forms. PMID: 30927014 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - April 1, 2019 Category: ENT & OMF Tags: HNO Source Type: research

ICD-10 Symptom Rating questionnaire for assessment of psychological comorbidities in patients with chronic tinnitus.
CONCLUSION: The ISR is a useful tool for measuring psychological comorbidities in patients with chronic tinnitus as well as short-term treatment response. Therapeutic approaches for chronic tinnitus should address stress-related tension, depressive symptomatology and coping strategies such as maladaptive eating behaviours. PMID: 30927015 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - April 1, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Reactions in the organ of Corti to electrical stimulation : StED technology for detecting changes].
Authors: Peter MN, Paasche G, Reich U, Lenarz T, Warnecke A Abstract Increasing numbers of cochlear implant patients have residual hearing. Despite surgical and pharmacological efforts to preserve residual hearing, a significant number of these patients suffer a late, unexplained loss of residual hearing. Surgical trauma can be excluded as the cause. To investigate this phenomenon and because cells in their native environment react differently to stimuli (such as electrical current) than isolated cells, whole-organ explants from cochleae may be a better model. For early detection of synaptic changes in th...
Source: HNO - March 20, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Principles of interventional treatment in epistaxis].
Authors: Reißberg S, Hartmann M Abstract Epistaxis is a common ear, nose, and throat emergency, but rarely a direct cause for hospital admission. Patients who receive inpatient treatment usually suffer from recurrent posterior epistaxis. Despite otolaryngologic measures such as posterior packing or surgery, bleeding may recur or continue or the source may not be surgically accessible. For these patients, endovascular therapy is a real, sometimes the only, treatment option. In addition to idiopathic causes of posterior epistaxis, the cause may also be symptomatic. In this case, the cause must be iden...
Source: HNO - March 20, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[The terminal hypoglossal nerve and its anatomical variability].
Authors: Heiser C, Knopf A, Hofauer B Abstract Upper airway stimulation plays an increasingly important role in the treatment of obstructive sleep apnea (OSA). The target of stimulation is the hypoglossal nerve (N. XII), which-as a pure motor nerve-innervates the intrinsic and extrinsic tongue muscles. By selectively stimulating individual nerve fibers, the upper airway can be opened by protruding the tongue. The N. XII has a number of anatomical variants, which are decisive during surgical implantation of these pacemaker systems. Intraoperative neuromonitoring is very helpful in this regard. Ac...
Source: HNO - March 16, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Hidden hearing loss-damage to hearing processing even with low-threshold noise exposure?]
CONCLUSION: Noise trauma initially results in hair cell damage. After recovery, hearing loss may persist, which can be due to synaptic lesions in the first neuron. An adequate testbattery has to be developped. PMID: 30874853 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - March 16, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Medical examination: Preparation for ENT specialisation : Part  41].
[Medical examination: Preparation for ENT specialisation : Part 41]. HNO. 2019 Mar 14;: Authors: Eichhorn T Abstract PMID: 30874854 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - March 16, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Guideline: Auditory Processing and Perception Disorders: Diagnostics : S1-Guideline of The German Society of Phoniatrics and Pediatric Audiology].
Authors: Nickisch A, Kiese-Himmel C, Massinger C, Ptok M, Schönweiler R Abstract In accordance with international consensus papers, auditory processing disorders (APD) are defined as disorders of central processes of hearing. Following the establishment of a commission of experts from the German Society for Phoniatrics and Pediatric Audiology, the existing S1 guideline was revised and updated. In this chapter, a position is taken on the clinical diagnostics of APD as well as on the delimitation of similar disorders. PMID: 30874855 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - March 16, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Recent developments in head and neck immunology : A basis for novel therapeutic strategies?]
This article will provide a compact overview about recent developments in this rapidly growing field in otorhinolaryngology which might establish the basis for promising therapeutic strategies for previously insufficiently treatable disorders of the head and neck. PMID: 30874856 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - March 16, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[A  sound reproduction system using wave field synthesis to simulate everyday listening conditions].
CONCLUSION: Wave field synthesis is a useful tool to simulate everyday listening conditions in a reproducible laboratory environment. This technique can complement established clinical methods to assess the benefit of a hearing device fitting or of signal preprocessing algorithms in dynamic listening conditions. PMID: 30859252 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - March 13, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Comment on the European Tinnitus Guideline].
Authors: Hesse G Abstract PMID: 30847512 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - March 10, 2019 Category: ENT & OMF Tags: HNO Source Type: research

A  multidisciplinary European guideline for tinnitus: diagnostics, assessment, and treatment.
A multidisciplinary European guideline for tinnitus: diagnostics, assessment, and treatment. HNO. 2019 Mar 07;: Authors: Cima RFF, Mazurek B, Haider H, Kikidis D, Lapira A, Noreña A, Hoare DJ Abstract PMID: 30847513 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - March 10, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Declaration of financial and non-financial interests in CME courses of Springer Medizin : Implementation of the regulation on the "Code on Continuing Medical Education" of the Medical Chamber North Rhine].
[Declaration of financial and non-financial interests in CME courses of Springer Medizin : Implementation of the regulation on the "Code on Continuing Medical Education" of the Medical Chamber North Rhine]. HNO. 2019 Mar 06;: Authors: Herrmann P, Griebenow R Abstract PMID: 30840089 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - March 8, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Calibration of the Freiburg monosyllabic speech test].
Authors: Holube I, Steffens T, Winkler A Abstract PMID: 30840090 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - March 8, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Special issues for the 55th Inner Ear Biology Workshop 06.-08.09.2018 in Berlin : Basic research and clinical aspects-translational aspects of hearing research. German version].
Authors: Mazurek B, Knipper M, Biesinger E, Schulze H Abstract PMID: 30830286 [PubMed - in process] (Source: HNO)
Source: HNO - March 6, 2019 Category: ENT & OMF Tags: HNO Source Type: research

Schnarchen und obstruktive Schlafapnoe.
Authors: Abstract PMID: 30830287 [PubMed - in process] (Source: HNO)
Source: HNO - March 6, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Comparability of the adaptively measured Freiburger monosyllabic test and OlSa in noise].
Authors: Löhler J, Schönweiler R Abstract PMID: 30824974 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - March 5, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[The ICD-10 Symptom Rating questionnaire for assessment of psychological comorbidities in chronic tinnitus patients].
CONCLUSION: The ISR is a useful tool for measuring psychological comorbidities in patients with chronic tinnitus as well as for assessing short-term treatment response. Therapeutic approaches for chronic tinnitus should also consider stress-related tension, depressive symptomatology, and coping strategies such as maladaptive eating behaviors. PMID: 30806717 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - February 27, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Differential diagnosis and treatment of pituitary adenomas].
Authors: Hlaváč M, Sommer F, Karpel-Massler G, Wirtz R, Hoffmann T, Paľa A Abstract Pituitary adenomas are among the most common primary brain tumors. These tumors can produce all hormones of the anterior pituitary and thus cause endocrine diseases. Compression of the pituitary gland, the surrounding cranial nerves, or brain structures can lead to hypopituitarism, cranial nerve deficits, or diverse neurological symptoms. Visual impairment, typically with bitemporal hemianopsia, is the most common cardinal symptom. The diagnostic workup requires broad interdisciplinary cooperation. With the exception of pro...
Source: HNO - February 24, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Intermittent tinnitus-an empirical description. German version].
CONCLUSION: IT is associated with emotional reactions and situational impairment severe enough to trigger multiple treatment attempts, but usually does not result in severe impairment. Inner ear disorders and psychological changes are less frequent than in CT; therefore, treatment response and prognosis might be better. We suggest classification of tinnitus into acute single-episode (3 months) forms. PMID: 30796499 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - February 24, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Schirmer test for determining the moisture status of the nasal mucosa].
Authors: Stupp F, Weigel A, Hoffmann TK, Sommer F, Grossi AS, Lindemann J Abstract BACKGROUND: There is no established method to objectively measure the moisture status of nasal mucosa. In a pilot study it was shown that a nasal Schirmer test is a possible method. The aim of the current study was to check whether the nasal Schirmer test is suitable to define moisture status in cases with an expected pathological secretion. MATERIALS AND METHODS: Initially, 154 subjects participated, of whom n = 112 were included (healthy n = 65, deviated septum n = 47, ♂ 60, ♀&...
Source: HNO - February 22, 2019 Category: ENT & OMF Tags: HNO Source Type: research

Hearing interventions to prevent dementia.
Authors: Dawes P Abstract Hearing loss is a marker of risk for cognitive decline and dementia. Controlled hearing intervention studies of long-term cognitive outcomes are challenging, and thus the evidence for the impact of hearing interventions is primarily from observational studies and will likely continue to be from studies other than randomised controlled trials. Seven studies of hearing interventions with cognitive outcomes assessed over longer than 3 years are reviewed. Most were of low-to-moderate quality. One cochlear implant study had indeterminate findings. Of six hearing aid studies, thre...
Source: HNO - February 17, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Quality of life after functional aesthetic septorhinoplasty].
Authors: Gassner HG Abstract PMID: 30767055 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - February 17, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Negative effects of stripe conchotomy on intranasal conditioning].
CONCLUSION: Partial resection of the caudal part of the inferior turbinate may lead to disturbed intranasal conditioning of inspired air if performed too radically. Therefore, if possible, this procedure should be avoided and a more gentle mucosal procedure chosen. PMID: 30767056 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - February 17, 2019 Category: ENT & OMF Tags: HNO Source Type: research

Selected ENT symptoms in functional disorders of the upper cervical spine and temporomandibular joints.
Authors: Hölzl M, Behrmann R, Biesinger E, von Heymann W, Hülse R, Goessler UR, Arens C Abstract This paper discusses otorhinolaryngological symptoms associated with functional disorders of the upper cervical spine. Hints aimed to avoid misdiagnoses of cross-organ otorhinolaryngological symptoms as phobic or psychogenic disorders are presented. Clinically relevant neuroanatomical convergence of the upper cervical spine (occiput to C3) is fundamental for the interpretation of functional otorhinolaryngological symptoms. Based thereon, evidence for the most common cervical differential diagnoses of dizziness...
Source: HNO - February 13, 2019 Category: ENT & OMF Tags: HNO Source Type: research

The speed limit of outer hair cell electromechanical activity.
Authors: Santos-Sacchi J Abstract The outer hair cell of Corti's organ provides mechanical feedback into the organ to boost auditory perception. The fidelity of voltage-dependent motility has been estimated to extend beyond 50 kHz, where its force generation is deemed a requirement for sensitive high-frequency mammalian hearing. Recent investigations have shown, however, that the frequency response is substantially more low pass at physiological membrane potentials where the kinetics of prestin impose their speed limit. Nevertheless, it is likely that the reduced magnitude of electromotility is sufficient to...
Source: HNO - February 13, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[The subjective perception of the vertical-a valuable parameter for determination of peripheral vestibular disorder in Meni ère's disease in the chronic phase?]
[The subjective perception of the vertical-a valuable parameter for determination of peripheral vestibular disorder in Menière's disease in the chronic phase?] HNO. 2019 Feb 06;: Authors: Voß LJ, Zabaneh SI, Hölzl M, Olze H, Stölzel K Abstract The perception of verticality is mainly based on utricular afferent signals and central processing of the transmitted signals. However, there are also extracranial receptors that make a considerable contribution to the perception of verticality. With the subjective visual vertical (SVV) for the utricle and the subjective trunk vertical...
Source: HNO - February 7, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Diagnostics and treatment of olfactory dysfunction].
CONCLUSION: Since a 50% decrease in the prevalence of olfactory disturbances is unlikely, the lower patient numbers may relate to a more critical diagnosis. The use of olfactory training in clinics has increased significantly (from
Source: HNO - February 7, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Introduction to the new article type "technical comment"].
[Introduction to the new article type "technical comment"]. HNO. 2019 Feb;67(2):82 Authors: Plontke SK Abstract PMID: 30725154 [PubMed - in process] (Source: HNO)
Source: HNO - February 7, 2019 Category: ENT & OMF Tags: HNO Source Type: research

Hot Topic: Schilddr üse.
Hot Topic: Schilddrüse. HNO. 2019 Feb;67(2):80-81 Authors: Abstract PMID: 30725155 [PubMed - in process] (Source: HNO)
Source: HNO - February 7, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Models of tinnitus development : From cochlea to cortex].
Authors: Krauss P, Schilling A, Tziridis K, Schulze H Abstract The development of subjective tinnitus is still not mechanistically understood and existing models are controversially discussed. In this overview, the authors discuss three of the main models, all of which propose damage to the cochlea as the initial step in tinnitus development. Based on these models, a possible manifestation of tinnitus-related neuronal activity at the perceptually relevant level of the auditory pathway, the auditory cortex, is presented. Furthermore, it is demonstrated that one of the models offers a new view on the phenom...
Source: HNO - February 3, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Tinnitus: psychosomatic aspects].
Authors: Boecking B, Brueggemann P, Mazurek B Abstract Tinnitus is a common symptom of unclear origin that can be multifactorially caused and maintained. It is frequently, but not inevitably, associated with hearing loss. Emotional distress and maladaptive coping strategies - that are associated with or amplified by the tinnitus percept - pose key targets for psychological interventions. Once somatic contributors are identified and treated as applicable, psychological approaches comprise normalizing psychoeducational and psychotherapeutic interventions. Measures to improve hearing perception (e. g., hea...
Source: HNO - January 31, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Perspectives of genome editing in otorhinolaryngology].
CONCLUSIONS: In theory, genome editing could be used in otolaryngology to target disease-causing genomic loci specifically. However, various challenges have to be overcome until applications can be used clinically. PMID: 30689007 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - January 30, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Medical examination: Preparation for ENT specialisation : Part  40].
[Medical examination: Preparation for ENT specialisation : Part 40]. HNO. 2019 Jan 17;: Authors: Offergeld C, Shiraliyev K, Arndt S, Aschendorff A Abstract PMID: 30656351 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - January 20, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Comparison of piezoelectric and conventional osteotomy in rhinoplasty : A  systematic review].
CONCLUSION: Piezoelectric osteotomy resulted in a reduced propensity for postoperative edema and ecchymosis compared to the conventional osteotomy technique with a chisel. At this time, the results should be regarded as a trend. A definite recommendation favoring piezoelectric osteotomy cannot be made until more studies with higher patient numbers become available. PMID: 30649568 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - January 18, 2019 Category: ENT & OMF Tags: HNO Source Type: research

Endoskopie und Bildgebung.
Authors: Abstract PMID: 30645683 [PubMed - in process] (Source: HNO)
Source: HNO - January 17, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Immuno-oncology of head and neck tumors].
Authors: Kasper S, Hussain T, Virchow I, Stuschke M, Lang S Abstract Treatment of patients with squamous cell carcinoma of the head and neck (SCCHN) is nowadays multidisciplinary. Therapeutic concepts include modern surgical and radiation techniques as well as systemic therapies. However, the prognosis of these patients is still poor for all stages. In the recurrent or metastatic situation after definitive therapy, there is an indication for palliative systemic treatment, whereby classical platinum-based chemotherapy and the monoclonal epidermal growth factor receptor (EGFR) antibody cetuximab are established, and ...
Source: HNO - January 14, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Maximum monosyllabic score as a  predictor for cochlear implant outcome].
CONCLUSION: The preoperatively measured PBmax may be used as a predictor for the minimum speech perception obtained with CI. This is of high clinical relevance for CI candidates with a PBmax above zero. PMID: 30635677 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - January 14, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Neck dissection-Surgical treatment of cervical lymphatic drainage pathways].
Authors: Vahl JM, Hoffmann TK Abstract Neck dissection (ND) is an essential component of treatment in head and neck squamous cell carcinoma (HNSCC). The extent of ND depends on primary tumor location and T and N stage. Trials have demonstrated improved survival for cN+ status with therapeutic ND as well as for cN0 status with selective ND if the primary has a high incidence of occult metastasis. The accuracy of the procedure is of prognostic relevance. In the prognostic model of the TNM classification, the parameter "N" does not only reflect the number of affected lymph nodes, but also thei...
Source: HNO - January 10, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Reasons for the development of allergies in children].
Authors: Klimek L, Wollenberg B, Guntinas-Lichius O, Pfaar O, Koennecke M Abstract Allergies are one of the most common chronic diseases in childhood, contributing to a tremendous medical and economical burden in health care systems of most industrialized countries. The development of allergies is dependent on a complex interaction of-among others-environmental factors, nutrition, genetic and epigenetic mechanisms as well as the microbiome. These diverse factors can influence early life immune regulation including innate and adaptive immune mechanisms in a complex fashion. In case of any Childhood al...
Source: HNO - January 6, 2019 Category: ENT & OMF Tags: HNO Source Type: research

[Guideline: Auditive Processing and Perception Disorders: Definition : Guideline of the German Society of Phoniatrics and Pediatric Audiology].
Authors: Ptok M, Kiese-Himmel C, Nickisch A Abstract In accordance with international consensus papers, Auditory Processing Disorders are defined here as disorders of central processes of hearing, which enable, among other things, the pre-conscious and conscious analysis, differentiation, and identification of changes in time, frequency, and intensity of acoustic or auditory speech signals as well as processes of binaural interaction (e. g., for localization, lateralization, noise clearance, and summation) and dichotic processing. Following the establishment of a commission of experts from the German Society...
Source: HNO - December 15, 2018 Category: ENT & OMF Tags: HNO Source Type: research

Dank an die Gutachter 2018.
Authors: PMID: 30539197 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - December 14, 2018 Category: ENT & OMF Tags: HNO Source Type: research

[Complications and complication management in rhinology].
Authors: Beule AG Abstract PMID: 30506313 [PubMed - in process] (Source: HNO)
Source: HNO - December 8, 2018 Category: ENT & OMF Tags: HNO Source Type: research

Innenohrschwerh örigkeit, Tinnitus.
Innenohrschwerhörigkeit, Tinnitus. HNO. 2018 Jun;66(6):416-417 Authors: PMID: 30506314 [PubMed - in process] (Source: HNO)
Source: HNO - December 8, 2018 Category: ENT & OMF Tags: HNO Source Type: research

[The adaptive Freiburg monosyllabic test in noise : Development of a  procedure and comparison of the results with the Oldenburg sentence test].
CONCLUSION: The Freiburg monosyllabic test can not only be used for quantifying discrimination loss in percentage terms, but also to measure the 50% speech recognition threshold with an adaptive algorithm. However, the procedure of the adaptive Freiburg monosyllabic test is more time consuming than that of the Oldenburg sentence test. Concerning a possible missing correlation between the results for 50% speech discrimination, further studies with hearing-impaired persons are needed. PMID: 30519714 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - December 8, 2018 Category: ENT & OMF Tags: HNO Source Type: research

[Erratum to: Management of acute vertigo and dizziness : Patients in emergency departments in Germany].
Authors: Löhler J, Eßer D, Wollenberg B, Walther LE Abstract PMID: 30506084 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - December 5, 2018 Category: ENT & OMF Tags: HNO Source Type: research

[Report from the 12th  Congress of the European Laryngological Society : London, 16-19 May 2018].
[Report from the 12th Congress of the European Laryngological Society : London, 16-19 May 2018]. HNO. 2018 Nov 27;: Authors: Sittel C Abstract PMID: 30483828 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - December 1, 2018 Category: ENT & OMF Tags: HNO Source Type: research

[Current treatment concepts in head and neck cancer : Highlights of the 2018 ASCO meeting].
Authors: Hoffmann TK Abstract PMID: 30488090 [PubMed - in process] (Source: HNO)
Source: HNO - December 1, 2018 Category: ENT & OMF Tags: HNO Source Type: research

Implantierbare H örsysteme.
Implantierbare Hörsysteme. HNO. 2018 Dec;66(12):876-877 Authors: Abstract PMID: 30488091 [PubMed - in process] (Source: HNO)
Source: HNO - December 1, 2018 Category: ENT & OMF Tags: HNO Source Type: research

[Obituary for Prof. Dr. med. Henning Bier (1957-2018) : Director of the Otorhinolaryngology Department at the Klinikum rechts der Isar of the Technical University of Munich from 2007 to 2018].
Authors: Hoffmann T Abstract PMID: 30478675 [PubMed - as supplied by publisher] (Source: HNO)
Source: HNO - November 28, 2018 Category: ENT & OMF Tags: HNO Source Type: research