From liver to hormones: The endocrine consequences of cirrhosis
This article provides a comprehensive review of the epidemiology, pathophysiology, diagnosis, and treatment of endocrine disturbances in liver cirrhosis. The review was conducted using the PubMed/Medline, EMBASE, and Scielo databases, encompassing 172 articles. Liver cirrhosis is associated with endocrine disturbances, including diabetes, hypoglycemia, sarcopenia, thyroid dysfunction, hypogonadotropic hypogonadism, bone disease, adrenal insufficiency, growth hormone dysfunction, and secondary hyperaldosteronism. The optimal tools for diagnosing diabetes and detecting hypoglycemia are the oral glucose tolerance test and con...
Source: World Journal of Gastroenterology : WJG - April 5, 2024 Category: Gastroenterology Authors: Juan Eduardo Quiroz-Aldave Elman Rolando Gamarra-Osorio Mar ía Del Carmen Durand-Vásquez Luciana Del Pilar Rafael-Robles Jhean Gabriel Gonz áles-Yovera Mar ía Alejandra Quispe-Flores Luis Alberto Concepci ón-Urteaga Alejandro Rom án-González Jos é Source Type: research
Monitoring adrenal insufficiency through salivary steroids: a pilot study
CONCLUSIONS: None of the GRTs mimics normal glucocorticoid rhythmicity and exposure. SalE, SalF and Z-score may be useful markers for monitoring and comparing different GRTs. Excess glucocorticoid in early afternoon best associated with depressive symptoms and worse life and sleep quality.PMID:38571387 | DOI:10.1093/ejendo/lvae037 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - April 4, 2024 Category: Endocrinology Authors: Lorenzo Tucci Flaminia Fanelli Ilaria Improta Valentina Bissi Claudia Lena Greta Galante Marco Mezzullo Matteo Magagnoli Anna Bianca Lalumera Giacomo Colombin Kimberly Coscia Laura Rotolo Valentina Vicennati Uberto Pagotto Guido Di Dalmazi Source Type: research
Monitoring adrenal insufficiency through salivary steroids: a pilot study
CONCLUSIONS: None of the GRTs mimics normal glucocorticoid rhythmicity and exposure. SalE, SalF and Z-score may be useful markers for monitoring and comparing different GRTs. Excess glucocorticoid in early afternoon best associated with depressive symptoms and worse life and sleep quality.PMID:38571387 | DOI:10.1093/ejendo/lvae037 (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - April 4, 2024 Category: Endocrinology Authors: Lorenzo Tucci Flaminia Fanelli Ilaria Improta Valentina Bissi Claudia Lena Greta Galante Marco Mezzullo Matteo Magagnoli Anna Bianca Lalumera Giacomo Colombin Kimberly Coscia Laura Rotolo Valentina Vicennati Uberto Pagotto Guido Di Dalmazi Source Type: research
IJERPH, Vol. 21, Pages 443: User Manual for Coping Strategies Inventory Short Form (CSI-SF) & mdash;The Jackson Heart Study
In this study, the CSI-SF was assessed to be a reliable and valid instrument for measuring coping strategies. The CSI-SF serves the purpose of developing an inner voice that can assist with understanding how people cope with everyday life. The information gathered from the administration of the CSI-SF can inform investigators about environmental cues and triggers that can also impact individual health. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - April 4, 2024 Category: Environmental Health Authors: Clifton Addison Brenda Jenkins Monique White Tags: Brief Report Source Type: research
Adrenal Insufficiency after Long-term use of Topical Glucocorticoids in Patients with Advanced Cutaneous T-cell Lymphomas: A Case Series
Acta Derm Venereol. 2024 Apr 2;104:adv19672. doi: 10.2340/actadv.v104.19672.NO ABSTRACTPMID:38566532 | DOI:10.2340/actadv.v104.19672 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 3, 2024 Category: Dermatology Authors: Valerie Glutsch Patrick Schummer Ann-Cathrin Koschker Matthias Goebeler Marion Wobser Source Type: research
Adrenal Insufficiency after Long-term use of Topical Glucocorticoids in Patients with Advanced Cutaneous T-cell Lymphomas: A Case Series
Acta Derm Venereol. 2024 Apr 2;104:adv19672. doi: 10.2340/actadv.v104.19672.NO ABSTRACTPMID:38566532 | DOI:10.2340/actadv.v104.19672 (Source: Acta Derm Venereol A...)
Source: Acta Derm Venereol A... - April 3, 2024 Category: Dermatology Authors: Valerie Glutsch Patrick Schummer Ann-Cathrin Koschker Matthias Goebeler Marion Wobser Source Type: research
Adrenal Insufficiency after Long-term use of Topical Glucocorticoids in Patients with Advanced Cutaneous T-cell Lymphomas: A Case Series
Acta Derm Venereol. 2024 Apr 2;104:adv19672. doi: 10.2340/actadv.v104.19672.NO ABSTRACTPMID:38566532 | DOI:10.2340/actadv.v104.19672 (Source: Acta Derm Venereol A...)
Source: Acta Derm Venereol A... - April 3, 2024 Category: Dermatology Authors: Valerie Glutsch Patrick Schummer Ann-Cathrin Koschker Matthias Goebeler Marion Wobser Source Type: research
Adrenal Insufficiency after Long-term use of Topical Glucocorticoids in Patients with Advanced Cutaneous T-cell Lymphomas: A Case Series
Acta Derm Venereol. 2024 Apr 2;104:adv19672. doi: 10.2340/actadv.v104.19672.NO ABSTRACTPMID:38566532 | DOI:10.2340/actadv.v104.19672 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 3, 2024 Category: Dermatology Authors: Valerie Glutsch Patrick Schummer Ann-Cathrin Koschker Matthias Goebeler Marion Wobser Source Type: research
Convolutional Neural Networks To Study Contrast-Enhanced Magnetic Resonance Imaging Based Skeletal Calf Muscle Perfusion In Peripheral Artery Disease
Peripheral artery disease (PAD) is associated with impaired blood flow in the lower extremities and histopathological changes of the skeletal calf muscles resulting in abnormal microvascular perfusion. We studied the use of convolutional neural networks (CNNs) to differentiate PAD patients from matched controls by utilizing perfusion pattern features from contrast-enhanced magnetic resonance imaging (CE-MRI) of the skeletal calf muscles. We acquired CE-MRI based skeletal calf muscle perfusion in 56 individuals (36 PAD patients, 20 matched controls). (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 3, 2024 Category: Cardiology Authors: Bijen Khagi, Tatiana Belousova, Christina M. Short, Addison Taylor, Jean Bismuth, Dipan J. Shah, Gerd Brunner Source Type: research
Convolutional Neural Networks to Study Contrast-Enhanced Magnetic Resonance Imaging –Based Skeletal Calf Muscle Perfusion in Peripheral Artery Disease
Peripheral artery disease (PAD) is associated with impaired blood flow in the lower extremities and histopathologic changes of the skeletal calf muscles, resulting in abnormal microvascular perfusion. We studied the use of convolution neural networks (CNNs) to differentiate patients with PAD from matched controls using perfusion pattern features from contrast-enhanced magnetic resonance imaging (CE-MRI) of the skeletal calf muscles. We acquired CE-MRI based skeletal calf muscle perfusion in 56 patients (36 patients with PAD and 20 matched controls). (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 3, 2024 Category: Cardiology Authors: Bijen Khagi, Tatiana Belousova, Christina M. Short, Addison Taylor, Jean Bismuth, Dipan J. Shah, Gerd Brunner Source Type: research
1. “Am I normal? Am I dying? Am I okay?”: A qualitative study examining the attitudes and practices of adolescents and young adults regarding vulvovaginal health
This study explored AYA understanding, attitudes, knowledge, and practices regarding vulvovaginal health, hygiene, and care, with particular attention to the positive and negative influences of social media. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Roxanne Rengifo, David Williams, Gabrielle D'Ambrosi, Grace Leahy, Jessica Addison, Areej Hassan Source Type: research
An Examination of Psycho-Behavioral Risk and Resilience in People with Chronically Painful Knee Osteoarthritis
Knee osteoarthritis (OA) is a common chronic condition that often results in high levels of pain severity and functional impairment. People with chronic pain tend to have poor sleep and are at greater psychological risk for experiencing persistent negative mood states. Additionally, measurements of psychological resilience also tend to be lower in people with knee OA. However, there are still mixed findings within the literature as to the exact relationships between psychological risk/resilience, sleep quality, pain and functioning in people with chronic pain. (Source: The Journal of Pain)
Source: The Journal of Pain - April 1, 2024 Category: Materials Science Authors: Daniel A. Kusko, Pavithra A. Thomas, Adriana Addison, Tammie L. Quinn, Cesar E. Gonzalez, Kimberly T. Sibille, Roger B. Fillingim, Robert E. Sorge, Burel R. Goodin Source Type: research
A Comprehensive Pain-Related Risk And Protective Index And Machine Learning Brain Age Gap
We reported that greater chronic pain severity and socioenvironmental risk and lower biobehavioral/psychosocial resilience are associated with higher allostatic load across multiple measures. The purpose of this study was to examine the relationship between a combined measure of chronic pain, socioenvironmental status, and biobehavioral/psychosocial resilience with a measure of allostatic load, predicted-chronological brain age gap (BAG). (Source: The Journal of Pain)
Source: The Journal of Pain - April 1, 2024 Category: Materials Science Authors: Angela Mickle, Jared J. Tanner, Udell Holmes, III, Brittany Addison, Kenia Rangel, Josue Cardoso, Cynthia Garvan, Roland Staud, Hrishikesh Deshpande, Song Lai, Adriana Addison, David Redden, Burel R. Goodin, Catherine C. Price, Roger B. Fillingim, Kimberl Tags: Clinical and/or Translational Science Source Type: research
Cancers, Vol. 16, Pages 1374: MGMT Methylation and Differential Survival Impact by Sex in Glioblastoma
Conclusions: In this study, females had higher mean and individual CpG site methylation and received a greater PFS and OS benefit by MGMT methylation that was not seen in males despite equal degrees of CpG methylation. (Source: Cancers)
Source: Cancers - March 31, 2024 Category: Cancer & Oncology Authors: Addison E. Barnett Ahmad Ozair Anas S. Bamashmos Hong Li David S. Bosler Gabrielle Yeaney Assad Ali David M. Peereboom Justin D. Lathia Manmeet S. Ahluwalia Tags: Article Source Type: research
The Impact of Pre-Trauma Steroid Use on Wound Healing and Outcomes
This study presents data on pre-trauma steroid use, a topic underrepresented in the trauma literature. Long-term steroid use has been linked to impaired wound healing, compromised immune responses, and hindrance of bone healing, alongside the potential for adrenal insufficiency during traumatic events. The aim of this study was to conduct a retrospective analysis of clinical outcomes for trauma patients with chronic steroid use. Examining adult trauma cases with pre-trauma steroid use at a level 1 trauma center (January 2016-September 2023), we identified 18 patients (58.6 ± 19.4 years, 55.6% males). All were on prednison...
Source: The American Surgeon - March 30, 2024 Category: Surgery Authors: Kaleb Derouen Sarah Aleman Harrison Travis John P Hunt Alan Marr Patrick Greiffenstein Lance Stuke Jonathan Schoen Alison Smith Source Type: research
