Widespread Pressure Pain Hypersensitivity in Musculoskeletal and Nerve Trunk Areas as Sign of Altered Nociceptive Processing in Unilateral Plantar Heel Pain
Plantar heel pain is a foot condition commonly treated by healthcare providers16. Subjects with this condition report insidious sharp pain under the plantar surface of the heel, usually spreading from the medial border of the plantar fascia to its insertion at the medial tuberosity of the calcaneus1. The pain increases in the morning with the first step after getting out of bed, after prolonged periods of inactivity and/or at the beginning of a workout3. Due to the presence of degenerative changes and the absence of inflammation in the plantar fascia14, it has been proposed that the proper term for this pain condition is p...
Source: The Journal of Pain - August 16, 2018 Category: Materials Science Authors: Gustavo Plaza-Manzano, Marta R íos-León, Patricia Martín-Casas, Lars Arendt-Nielsen, César Fernández-de-las-Peñas, Ricardo Ortega-Santiago Source Type: research

Risk of pain and gastrointestinal complaints at six months after elective abdominal surgery
The incidence of chronic postoperative abdominal pain (CPAP) after abdominal surgery is estimated at 11%. CPAP is associated with an increase of gastrointestinal symptoms and decreases overall quality of life 5, 10. Around 30% of patients after gastrointestinal surgery report having pain-related interference with mood, sleep and enjoyment of life and 12% visit the emergency department for pain related symptoms 36. Intra-abdominal adhesions are deemed as the cause of CPAP in 60% of patients. In these patients no anatomic or functional abnormalities are found apart from adhesions 32. (Source: The Journal of Pain)
Source: The Journal of Pain - August 11, 2018 Category: Materials Science Authors: Chema Strik, Barend van den Beukel, Dagmar van Rijckevorsel, Martijn W.J. Stommel, Richard P.G. ten Broek, Harry van Goor Source Type: research

Cost-effectiveness and cost-utility of internet-delivered exposure therapy for fibromyalgia: results from a randomized controlled trial
Fibromyalgia (FM) is a disabling chronic pain disorder, with a prevalence ranging between 2 and 4% 25,53,57, often presenting with a range of other somatic and psychiatric symptoms such as fatigue, sleep disturbances, anxiety and depression. Furthermore, FM is a costly disorder for both healthcare providers and society. One study 7 showed that FM patients on average utilize four times as many physician visits, twice as many other outpatient visits, and four times more emergency room visits compared with other primary care patients. (Source: The Journal of Pain)
Source: The Journal of Pain - August 11, 2018 Category: Materials Science Authors: Maria Hedman-Lagerl öf, Erik Hedman-Lagerlöf, Brjánn Ljótsson, Rikard K Wicksell, Ida Flink, Erik Andersson Tags: Original Reports Source Type: research

Spinal 5-HT1AR contributes to the analgesia of acupoint catgut embedding by inhibiting phosphorylation of the NMDA receptor GluN1 subunit in CFA-induced inflammatory pain in rats
Acupuncture, which can be performed in several different ways, has been widely used for managing many diseases, including chronic inflammatory pain, especially in drug-refractory patients 3, 4, 55. Several large studies have also provided evidence that acupuncture is a relatively safe treatment 34, 47, 50. (Source: The Journal of Pain)
Source: The Journal of Pain - August 10, 2018 Category: Materials Science Authors: Wen-Qiang Cui, Wen-Shan Sun, Fei Xu, Xue-Ming Hu, Wei Yang, Yang Zhou, Li-Xia Du, Wen-Wen Zhang, Qi-Liang Mao-Ying, Wen-Li Mi, Yu-Xia Chu, Yan-Qing Wang Source Type: research

The Pain Course: 12 and 24 month outcomes from a randomised controlled trial of an internet-delivered pain management program provided with different levels of clinician support
Internet-delivered pain management programs have considerable potential for increasing access to evidence-based pain management [16, 25, 31]. Internet-delivered pain management programs are often based on the same principles and teach the same self-management skills as face-to-face programs. However, these programs employ carefully designed online modules to teach pain management information and support patients to develop their self-management skills [36]. These programs can be offered in clinician guided formats, where patients are provided weekly support throughout the program via telephone or email, or in more self-gui...
Source: The Journal of Pain - August 9, 2018 Category: Materials Science Authors: Blake F Dear, Milena Gandy, Eyal Karin, Rhiannon Fogliati, Vincent J Fogliati, Lauren G Staples, Bethany M Wootton, Louise Sharpe, Nickolai Titov Source Type: research

Exploring the relationships between altered body perception, limb position sense, and limb movement sense in complex regional pain syndrome
Perceiving the size, shape, position and movement of our limbs is essential to help us interact adequately with our environment. An extensive literature shows that chronic pain conditions are often accompanied by various distortions in body perception, which can include changes in perception of the size, shape and temperature of the painful limb11,17,18,22,36. In addition, alterations of the sense of limb position (assessed with the limb in a static posture) have also been observed1,11,33. For example, individuals with Complex Regional Pain Syndrome (CRPS) were shown to overestimate the angular position of their painful wr...
Source: The Journal of Pain - August 9, 2018 Category: Materials Science Authors: Cl émentine Brun, Nicolas Giorgi, Anne-Marie Pinard, Martin Gagné, Candida S. McCabe, Catherine Mercier Source Type: research

Measurement properties of Visual Analogue Scale, Numeric Rating Scale and Pain Severity subscale of the Brief Pain Inventory in patients with low back pain: a systematic review
Low back pain (LBP) is the most disabling health condition worldwide 33. Measuring the impact of LBP on patients ’ lives is fundamental to monitor clinical management and to study the (cost-) effectiveness of treatments 4. Patients with LBP have indicated that the most important domains to be measured are: physical functional activities, pain reduction, quality of life, enjoyment of life, emotional well-bein g, and fatigue 9, 43, 103. A core outcome set initiative (involving patients) aimed at standardizing measurement for LBP identified four core outcome domains for clinical trials: physical functioning, pain intens...
Source: The Journal of Pain - August 9, 2018 Category: Materials Science Authors: Alessandro Chiarotto, Lara J. Maxwell, Raymond W. Ostelo, Maarten Boers, Peter Tugwell, Caroline B. Terwee Source Type: research

Do people with chronic musculoskeletal pain have impaired motor imagery? A meta-analytical systematic review of the left/right judgement task
The brain contains representations of the body that are required for normal functioning, including goal directed movements and behavior20. This concept of a body schema17 includes integrated sensory inputs and ideas about ones body1. Both executed and imagined movements are subserved by this online representation of the body45. One way of investigating the integrity of the body schema is by the use of implicit motor imagery. The left/right judgement task (LRJT) is an implicit motor imagery task that involves viewing images of a body-part and determining whether each image belongs to, or is rotating towards, the left or rig...
Source: The Journal of Pain - August 8, 2018 Category: Materials Science Authors: John D. Breckenridge, Karen A. Ginn, Sarah B. Wallwork, James H. McAuley Tags: Review Article Source Type: research

Associations between adolescent chronic pain and prescription opioid misuse in adulthood
Prescription opioid misuse is defined as the consumption of opioids in manner or dose other than prescribed, consuming others ’ prescriptions, or consuming opioids for feelings that are elicited (i.e. to get high)31. Prescription opioid misuse is a serious public health epidemic in the United States. In 2013, almost 10 million Americans (4.9% of the adult population) reported prescription opioid misuse 15. Prescription o pioid misuse was found to be most prevalent among young adults 18-26 years of age, of whom 7.1% reported opioid misuse over the past 12 months in 2016 in the United States 4. (Source: The Journal of Pain)
Source: The Journal of Pain - August 8, 2018 Category: Materials Science Authors: Cornelius B. Groenewald, Emily F. Law, Emma Fisher, Sarah E. Beals-Erickson, Tonya M. Palermo Source Type: research

Prevalence and profile of High Impact Chronic Pain in the United States
Chronic pain is a major global health issue9 with immense social and economic impacts,4,8 yet has proven difficult to operationalize.25 Chronic pain is often defined by pain duration,1,13,23,25,26 where pain persisting 3-6 months or more since onset can yield prevalence estimates for chronic pain ranging from 19% to 43%, or up to 116 million Americans.10,12,15,19,26 While conceptually appealing, this hotly debated7 approach does not consider the multi-dimensional nature of chronic pain, namely the presence of activity limitations and participation restrictions,5,17,30-36 classifications recognized by the World Health Organ...
Source: The Journal of Pain - August 7, 2018 Category: Materials Science Authors: Mark H. Pitcher, Michael Von Korff, M. Catherine Bushnell, Linda Porter Tags: Original Reports Source Type: research

Masthead
(Source: The Journal of Pain)
Source: The Journal of Pain - July 27, 2018 Category: Materials Science Source Type: research

Editorial Board
(Source: The Journal of Pain)
Source: The Journal of Pain - July 27, 2018 Category: Materials Science Source Type: research

Table of Contents
(Source: The Journal of Pain)
Source: The Journal of Pain - July 27, 2018 Category: Materials Science Source Type: research

Subgroup perspectives on chronic pain and its management after spinal cord injury
Up to 80% of individuals develop chronic pain within their first year after a spinal cord injury (SCI).12 Although all pain types that occur after injury can be problematic, the persistent neuropathic pain types in particular, negatively influence quality of life and independent living after SCI by interfering with sleep, mood, physical and social activities.33,3,53,29,22,21,47 Because most pharmacological approaches only have limited effectiveness in reducing the intensity and impact of neuropathic pain in this population, optimal pain management strategies need to incorporate multiple ways to reduce pain. (Source: The Journal of Pain)
Source: The Journal of Pain - July 26, 2018 Category: Materials Science Authors: Eva Widerstr öm-Noga, Kim D. Anderson, Salomé Perez, Alberto Martinez-Arizala, Jessica M. Cambridge Tags: Original Reports Source Type: research

You'd better believe it: The conceptual and practical challenges of assessing malingering in patients with chronic pain
Chronic pain is a prevalent and costly condition, with many patients receiving income support and funded treatment. Given that pain cannot be objectively assessed, patients may be suspected of exaggerating their pain and disability to receive additional funding. Although numerous methods of detecting malingering have been suggested, it is unclear whether clinicians can reliably identify malingering in patients with chronic pain. The present focus article was developed to assess the theoretical basis and empirical support for proposed methods of detecting malingering in patients with chronic pain. (Source: The Journal of Pain)
Source: The Journal of Pain - July 20, 2018 Category: Materials Science Authors: Natalie L. Tuck, Malcolm H. Johnson, Debbie J. Bean Tags: Focus Article Source Type: research

The Added Value of Qualitative Methodologies for Studying Emotional Disclosure About Pain
We thank Professor Cano and Professor Goubert for their excellent article regarding emotional disclosure of pain-related distress1 and agree that there are clear advantages to better integrating this form of emotional expression within both theoretical and clinical paradigms. One area that was surprisingly undeveloped, however, was the role for qualitative methodologies. We believe that qualitative methodologies offer direct added value for several aspects of the proposed research agenda. (Source: The Journal of Pain)
Source: The Journal of Pain - July 17, 2018 Category: Materials Science Authors: Timothy H. Wideman, Anne Hudon, Geoff Bostick Tags: Letter to the Editor Source Type: research

Sex and Race Differences in Pain Sensitization among Patients with Chronic Low Back Pain
Chronic low back pain (CLBP), one of the most common complaints seen by physicians, is a primary cause of disability in the United States and is associated with between $100 and $200 billion in annual costs.1,8,43,63,72 Although some patients with CLBP may have identifiable etiologies, for many there are no discernable mechanisms to account for their pain and dysfunction.9 There is growing evidence that like other chronic pain conditions, idiopathic CLBP involves changes in the central nervous system that result in pain augmentation. (Source: The Journal of Pain)
Source: The Journal of Pain - July 16, 2018 Category: Materials Science Authors: S.M. Meints, V. Wang, R.R. Edwards Tags: Original Reports Source Type: research

Randomized Trial of a Low Literacy Chronic Pain Self-Management Program: Analysis of Secondary Pain and Psychological Outcome Measures
Given the complex adverse effects of chronic pain on daily living, self-management training should be an essential component of care similar to self-management education for diabetes mellitus. However, systematic reviews have reported conflicting evidence regarding the effectiveness of self-management education for chronic pain and related conditions. A systematic review of self-management programs for osteoarthritis reported no significant effects on pain, function, or quality of life.21 On the other hand, a systematic review and meta-analysis found that multidisciplinary biopsychosocial rehabilitation training programs f...
Source: The Journal of Pain - July 15, 2018 Category: Materials Science Authors: Barbara J. Turner, Yuanyuan Liang, Natalia Rodriguez, Raudel Bobadilla, Maureen J. Simmonds, Zenong Yin Source Type: research

Effects of different parameters of continuous training and high-intensity interval training in the chronic phase of mouse model of complex regional pain syndrome type I
Complex regional pain syndrome type I (CRPS-I) is a neuropathy that can develop after deep tissue injury such as fractures or distensions without nerve damage.12,17 CRPS-I usually comprises two phases. The acute phase is the initial inflammatory period of the disease, with the best prognosis; and the neuropathic phase, with more complicated prognosis, which can result in severe cases of tissue hypotrophy associated with unbearable pain.7 (Source: The Journal of Pain)
Source: The Journal of Pain - July 10, 2018 Category: Materials Science Authors: Luiz Augusto Oliveira Belmonte, Thiago C ésar Martins, Daiana Cristina Salm, Aline Armiliato Emer, Bruna Hoffman de Oliveira, Khiany Mathias, Mariana Pereira Goldim, Verônica Vargas Horewicz, Anna Paula Piovezan, Franciane Bobinski, Fabrícia Petronilho Tags: Original Reports Source Type: research

The effect of pain on major cognitive impairment in older adults
Pain is a frequently reported problem by older adults; more than half of community-dwelling older adults and up to 70% of older adults in residential homes, experience pain, and the prevalence of chronic pain increases with advancing age.9,19 In older adults chronic pain interferes with daily activities, and has been associated with risk of developing disability,18 with falls,27,44 functional impairment and poor self-rated health.16,29,37,39,40 (Source: The Journal of Pain)
Source: The Journal of Pain - July 10, 2018 Category: Materials Science Authors: Guusje van der Leeuw, Emmeline Ayers, Suzanne G. Leveille, Annette H. Blankenstein, Henriette E. van der Horst, Joe Verghese Source Type: research

Structural consistency of the Pain Sensitivity Questionnaire in the Cooperative Health Research In South Tyrol (CHRIS) population-based study
Pain is amongst the most common symptoms that patients report to physicians and is often critical to manage.15 Pain sensitivity reflects individual pain perception, predicts acute post-operative pain and analgesic use,1,22,35 and may relate to chronic pain development.10 It shows large interindividual variability, challenging both objective experimental testing and clinical evaluation.11,30 The assessment of pain sensitivity is an important aspect for pain therapy, progress monitoring and etiology. (Source: The Journal of Pain)
Source: The Journal of Pain - July 6, 2018 Category: Materials Science Authors: Roberto Melotti, Ruth Ruscheweyh, Peter P. Pramstaller, Andrew A. Hicks, Cristian Pattaro Source Type: research

Acupuncture Resolves Persistent Pain and Neuroinflammation in a Mouse Model of Chronic Overlapping Pain Conditions
Chronic overlapping pain conditions (COPCs), such as fibromyalgia (FM), temporomandibular disorder (TMD), episodic migraine (EM), tension-type headache (TTH), and low back pain (LBP) affect over 100 million Americans and costs the US economy billions of dollars each year22. A hallmark of the COPCs is their idiopathic pathogenesis20. Each individual condition produces pain unexplained by clinical findings such as injury or inflammation97. Furthermore, each is characterized by pain that persists “beyond the normal time of healing”, thereby meeting the IASP definition of chronicity67. (Source: The Journal of Pain)
Source: The Journal of Pain - July 4, 2018 Category: Materials Science Authors: Seungtae Kim, Xin Zhang, Sandra C. O'Buckley, Mary Cooter, Jongbae J. Park, Andrea G. Nackley Source Type: research

Brain mechanisms of anticipated painful movements and their modulation by Manual Therapy in chronic Low Back Pain
Heightened anticipation and fear of movement-related pain has been linked to detrimental fear-avoidance behavior in chronic Low-Back Pain (cLBP). Spinal Manipulative Therapy (SMT) has been proposed to work partly by exposing patients to non-harmful but forceful mobilization of the painful joint, thereby disrupting the relationship between pain anticipation, fear, and movement. Here, we investigated the brain processes underpinning pain anticipation and fear of movement in cLBP, and their modulation by SMT, using functional Magnetic Resonance Imaging. (Source: The Journal of Pain)
Source: The Journal of Pain - July 3, 2018 Category: Materials Science Authors: Dan-Mikael Ellingsen, Vitaly Napadow, Ekaterina Protsenko, Ishtiaq Mawla, Matthew H. Kowalski, David Swensen, Deanna O'Dwyer-Swensen, Robert R. Edwards, Norman Kettner, Marco L Loggia Tags: Original Reports Source Type: research

Combination drug therapy for the management of low back pain and sciatica; systematic review and meta-analysis
Low back pain is a highly prevalent condition, causing considerable disability and burden globally19. Up to 70% of people will experience low back pain during their lifetime54. Patients with low back-related leg pain, such as sciatica, experience intense radiating leg pain that may be accompanied by neurological signs20 and both low back pain and sciatica are associated with high healthcare costs, work absenteeism and economic burden19,53. (Source: The Journal of Pain)
Source: The Journal of Pain - July 2, 2018 Category: Materials Science Authors: Dr Stephanie Mathieson, Dr Richard Kasch, Professor Christopher G. Maher, Dr Rafael Zambelli Pinto, Professor Andrew J. McLachlan, Professor Bart W. Koes, Associate Professor Chung-Wei Christine Lin Tags: Review Article Source Type: research

Persistent Post-Mastectomy Pain: Current Status and Future Directions
Breast cancer is the most commonly diagnosed form of cancer among women in the U.S., affecting over 250,000 patients per year42. While the incidence of breast cancer diagnoses continues to climb, advances in treatment have led to decreased mortality rates, as well as increased five-year survival rates (90.8%, 95% CI  = 90.5% to 91.1%). The increase in survivorship underscores the importance of attending to and optimizing quality of life for patients whose lives are extended by treatment. For female breast cancer survivors, persistent post-mastectomy/lumpectomy pain has been recognized as negatively impactin g the quali...
Source: The Journal of Pain - July 2, 2018 Category: Materials Science Authors: Raymond C. Tait, Kim Zoberi, McKenzie Ferguson, Kimberly Levenhagen, Rebecca A. Luebbert, Kevin Rowland, Gretchen B. Salsich, Christopher Herndon Tags: Review Article Source Type: research

Psychological factors associated with ultra-marathon runners ’ supra-normal pain tolerance: a pilot study
There is increasing evidence that athletes have higher pain tolerance than the general population.15,22,39,42,43,50 Supra-normal pain tolerance has been observed in a wide range of athletes, including marathon runners,22 triathletes,15 swimmers,43 rowers,39 ballet dancers,50 basketball players56 and contact sports athletes.42 A recent meta-analysis pooled the results of 12 studies investigating athletes ’ pain tolerance and concluded that athletes had significantly higher pain tolerance than normally active controls. (Source: The Journal of Pain)
Source: The Journal of Pain - July 2, 2018 Category: Materials Science Authors: Roebuck G.S., Urquhart D.M., Knox L., Fitzgerald P.B., Cicuttini F.M., Lee S., Fitzgibbon B.M. Source Type: research

Nociceptive and Cognitive Changes in a Murine Model of Polytrauma
With a global incidence estimated to be about 106 per 100,000 population, TBI is a leading cause of trauma-related disability 15. In the US more than 1.7 million injuries occur per year resulting in 250,000 hospitalizations and 52,000 deaths 9. The majority (75-80%) of all TBI cases are, however, mild and are accompanied by the rapid resolution of the immediate symptoms including disorientation, dizziness, tinnitus, nausea and balance problems 24. The incidence of TBI is higher overall in males than females, and is particularly common in the very young, adolescents and elderly 3. (Source: The Journal of Pain)
Source: The Journal of Pain - July 2, 2018 Category: Materials Science Authors: Peyman Sahbaie, Maral Tajerian, Phillip Yang, Karen Amanda Irvine, Ting-Ting Huang, Jian Luo, Tony Wyss-Coray, J David Clark Tags: Original Reports Source Type: research

Establishing a Research Agenda on Mobile Health Technologies and Later-Life Pain Using an Evidence-Based Consensus Workshop Approach
The health of aging populations in developed countries has not kept pace with improvements in life expectancy.9 Many older adults spend their final years coping with and managing multiple chronic conditions, many of which have pain as a primary symptom.17,29 Later-life pain is associated with substantial disability and suffering.17,29 Given the rapid increase in the number of aging adults living with chronic conditions and pain, rising healthcare costs, and shortage of caregivers to help care for affected individuals, experts have asked whether emerging technologies, in particular mobile health (mHealth) devices, can help ...
Source: The Journal of Pain - July 2, 2018 Category: Materials Science Authors: Elaine Wethington, Christopher Eccleston, Geri Gay, Rachael Gooberman-Hill, Patricia Schofield, Elizabeth Bacon, Wen Dombrowski, Robert Jamison, Max Rothman, Lauren Meador, Cara Kenien, Karl Pillemer, Corinna L öckenhoff, M. Carrington Reid Tags: Original Reports Source Type: research

Masthead
(Source: The Journal of Pain)
Source: The Journal of Pain - June 26, 2018 Category: Materials Science Source Type: research

Editorial Board
(Source: The Journal of Pain)
Source: The Journal of Pain - June 26, 2018 Category: Materials Science Source Type: research

Table of Contents
(Source: The Journal of Pain)
Source: The Journal of Pain - June 26, 2018 Category: Materials Science Source Type: research

Physical and psychosocial factors in the prevention of chronic pain in older age
Chronic pain is recognised as a major challenge as people age. Prevalence figures vary but broadly suggest that around half to two-thirds of adults aged 50+ are affected (more than four times the number of 18-25 years affected), and incidence rates are as high as 5.4% per year.7,15,24 Pain is one of the most widely cited symptoms of underlying disability in older adults and is linked with impaired physical capacity for basic and instrumental activities of daily living, poorer mobility and falls. (Source: The Journal of Pain)
Source: The Journal of Pain - June 24, 2018 Category: Materials Science Authors: D. Fancourt, A. Steptoe Source Type: research

Preoperative Neuropathic Pain Like Symptoms and Central Pain Mechanisms in Knee Osteoarthritis Predicts Poor Outcome 6 Months After Total Knee Replacement Surgery
Knee osteoarthritis (OA) pain has been traditionally attributed to the activation of peripheral nociceptors within the joint or peri-articular structures 49. Significant discordance between radiographic features and knee pain severity 31 has led to researchers investigating the central pain mechanisms with the identification of OA subgroups with different pain phenotypes 2, 4 –7,39,40. Up to 34% of OA patients exhibit neuropathic pain-like symptoms 25,26,42,53 (electric shock sensations 25,26, burning pain 14 and allodynia 48) which have been associated with symptoms of central pain facilitation 24,35. (Source: The Journal of Pain)
Source: The Journal of Pain - June 16, 2018 Category: Materials Science Authors: Thomas Kurien, Lars Arendt-Nielsen, Kristian K Petersen, Thomas Graven-Nielsen, Brigitte E. Scammell Tags: Original Reports Source Type: research

Exploring the Role of Negative Cognitions in the Relationship Between Ethnicity, Sleep, and Pain in Women With Temporomandibular Joint Disorder
Temporomandibular joint disorder (TMJD) consists of a cluster of chronic pain conditions characterized by pain in the jaw or surrounding muscles, which can lead to significant distress and functional limitation.5,26 Although there are documented ethnic differences in acute and chronic pain,31 the role of ethnicity in TMJD is somewhat inconsistent. The Orofacial Pain: Prospective Evaluation and Risk Assessment study has recently reported higher pain sensitivity in African American (AA) individuals relative to Caucasian individuals42 and a greater new-onset rate of TMJD for AA. (Source: The Journal of Pain)
Source: The Journal of Pain - June 8, 2018 Category: Materials Science Authors: Sheera F. Lerman, Claudia M. Campbell, Luis F. Buenaver, Mary Medak, Jane Phillips, Michelle Polley, Michael T. Smith, Jennifer A. Haythornthwaite Tags: Original Reports Source Type: research

Exploring the role of negative cognitions in the relationship between ethnicity, sleep and pain in women with temporomandibular joint disorder
Temporomandibular Joint Disorder (TMJD) consists of a cluster of chronic pain conditions characterized by pain in the jaw or surrounding muscles, which can lead to significant distress and functional limitation.5,26 While there are documented ethnic differences in acute and chronic pain,31 the role of ethnicity in TMJD is somewhat inconsistent. The OPPERA study has recently reported higher pain sensitivity in African American (AA) individuals relative to Caucasian individuals42 and a greater new-onset rate of TMJD for AA. (Source: The Journal of Pain)
Source: The Journal of Pain - June 8, 2018 Category: Materials Science Authors: Sheera F. Lerman, Claudia M. Campbell, Luis F. Buenaver, Mary Medak, Jane Phillips, Michelle Polley, Michael T. Smith, Jennifer A. Haythornthwaite Source Type: research

Nociception, pain, consciousness, and society: A plea for constrained use of pain-related terminologies
The science of pain has reached an exciting phase. New discoveries are pushing the limits of even the most basic ideas regarding underlying mechanisms, positioning the field at the threshold of advancing novel and efficacious treatments for diverse pain conditions. Given these rapid expansions, the potential impact of our work on society is inevitable and potentially profound. With influence, comes responsibility. Impact on society necessitates a more circumspect approach to how we communicate and expound our findings. (Source: The Journal of Pain)
Source: The Journal of Pain - June 8, 2018 Category: Materials Science Authors: A. Vania Apkarian Tags: Focus Article Source Type: research

The relationship of endocannabinoidome lipid mediators with pain and psychological stress in women with fibromyalgia – a case control study
Fibromyalgia (FM) is a heterogeneous and complex syndrome manifested as generalized hyperalgesia and chronic widespread musculoskeletal pain (CWP). Common symptoms of FM also include, stiffness, fatigue, sleep disturbances, and cognitive dysfunction1 and common co-morbidities include depression, anxiety, and stress.2 The prevalence of FM is 2-4%,3,4 peaks around 55-65 years of age, and shows a strong female predominance.5 FM results in physical and psychological distress, reduced quality of life, increased use of health resources, and loss of work productivity. (Source: The Journal of Pain)
Source: The Journal of Pain - June 6, 2018 Category: Materials Science Authors: Niclas Stensson, Nazdar Ghafouri, Malin Ernberg, Kaisa Mannerkorpi, Eva Kosek, Bj örn Gerdle, Bijar Ghafouri Tags: Original Reports Source Type: research

Spouse Criticism/Hostility Toward Partners with Chronic Pain: The Role of Spouse Attributions for Patient Control over Pain Behaviors
Observational (1,5,9,10,30,35), diary (6,23), and laboratory studies (7,8) primarily of married couples coping with chronic pain, indicate that high levels of criticism and hostility from one's spouse are linked to greater pain intensity and decreased function for partners afflicted with chronic pain. Less well established is what may account for such negative spouse behaviors toward their partners with chronic pain. (Source: The Journal of Pain)
Source: The Journal of Pain - June 2, 2018 Category: Materials Science Authors: John W. Burns, James Gerhart, Kristina M. Post, David A. Smith, Laura S. Porter, Asokumar Buvanendran, Anne Marie Fras, Francis J. Keefe Tags: Original Reports Source Type: research

Masthead
(Source: The Journal of Pain)
Source: The Journal of Pain - May 25, 2018 Category: Materials Science Source Type: research

Editorial Board
(Source: The Journal of Pain)
Source: The Journal of Pain - May 25, 2018 Category: Materials Science Source Type: research

Table of Contents
(Source: The Journal of Pain)
Source: The Journal of Pain - May 25, 2018 Category: Materials Science Source Type: research

The use of adjunct psychosocial interventions can decrease postoperative pain and improve the quality of clinical care in orthopedic surgery. A systematic review and meta-analysis of randomized controlled trials
The number of orthopedic surgeries performed each year is growing rapidly worldwide.38,46,88,119,153 For example, by 2030, total knee and hip arthroplasties are expected to reach 3.48 million (673% increase) and 572,000 (174% increase), respectively, in the United States alone.88 In Australia, the demand for knee replacement surgeries has increased by 150% over the past 10 years.10 Growth is expected to continue as the world's population continues to age and rates of obesity and osteoarthritis rise. (Source: The Journal of Pain)
Source: The Journal of Pain - May 25, 2018 Category: Materials Science Authors: Csenge Szeverenyi, Zoltan Kekecs, Alisa Johnson, Gary Elkins, Zoltan Csernatony, Katalin Varga Tags: Review Article Source Type: research

Cortical somatosensory excitability is modulated in response to several days of muscle soreness
Maladaptive neuroplasticity has been documented in the sensorimotor cortex of people with chronic musculoskeletal pain [13] and is suggested to be an important component of the transition from acute to chronic pain [21]. For instance, increased cortical activity and a medial shift of the cortical representation of the back, interpreted as an expansion of the back's representation into the foot and leg area, has been shown in people with chronic low back pain using magnetoencephalography [13]. In another study tactile stimulation on the back of low back pain patients demonstrated a shift in the locus of primary somatosensor...
Source: The Journal of Pain - May 24, 2018 Category: Materials Science Authors: Enrico DE MARTINO, Laura PETRINI, Siobhan SCHABRUN, Thomas GRAVEN-NIELSEN Tags: Original Reports Source Type: research

Intrinsic Activity of C57BL/6 Substrains Associates with High-Fat Diet-Induced Mechanical Sensitivity in Mice
Obesity and metabolic syndrome are increasing in an alarming fashion worldwide, and increasing attention is being paid to the strong relationship between obesity, metabolic syndrome and pain19. This growing correlation of obesity and pain has been investigated using numerous animal models, many utilizing differing strains of animals, diets, and obesity phenotypes, and it's clear that the genetic component underlying pain is a key contributor. Animal studies have identified important differences in pain associated with different strains of rodents20. (Source: The Journal of Pain)
Source: The Journal of Pain - May 24, 2018 Category: Materials Science Authors: Michael A. Cooper, Bryn O'Meara, Megan M. Jack, Dan Elliot, Bradley Lamb, Zair W. Khan, Blaise W. Menta, Janelle M. Ryals, Michelle K. Winter, Douglas E. Wright Source Type: research

Parent Responses to Child Pain During Intensive Interdisciplinary Pain Treatment and 1-Year Follow-Up
Impairment in youths with chronic pain is impacted by observable and unobservable (eg, emotional and cognitive) behaviors of those around them,11,25 particularly their caregivers. Parents and other caregivers are integral to the social context of all youths, including those with chronic pain.42 Unfortunately, parents of youths with chronic pain often experience increased levels of emotional distress, interpersonal difficulties, and financial hardships,14,16,29 which may impair their ability to respond effectively to their child's pain. (Source: The Journal of Pain)
Source: The Journal of Pain - May 17, 2018 Category: Materials Science Authors: Melissa Pielech, Dustin P. Wallace, Megan Fitzgerald, Cara M. Hoffart Tags: Original Report Source Type: research

Acceptance and Commitment Therapy for Prevention of Chronic Postsurgical Pain and Opioid Use in At-Risk Veterans: A Pilot Randomized Controlled Study
High levels of pain, significant anxiety, or depressive symptoms before surgery put patients at elevated risk for chronic pain and prolonged opioid use following surgery. The purpose of this preliminary study was to assess the efficacy of a 1-day Acceptance and Commitment Therapy (ACT) workshop in “at-risk” veterans for the prevention of chronic pain and opioid use following orthopedic surgery. In a randomized controlled trial, 88 at-risk veterans undergoing orthopedic surgery were assigned to treatment as usual (TAU; n = 44) or TAU plus a 1-day ACT workshop (n = 44). (Source: The Journal of Pain)
Source: The Journal of Pain - May 17, 2018 Category: Materials Science Authors: Lilian Dindo, M. Bridget Zimmerman, Katherine Hadlandsmyth, Barbara StMarie, Jennie Embree, James Marchman, Toni Tripp-Reimer, Barbara Rakel Tags: Original Report Source Type: research

Experimental Referred Pain Extends Toward Previously Injured Location: An Explorative Study
Musculoskeletal pain affects a vast majority of the population at some stage during the lifespan.4 After an initial painful musculoskeletal event, such as whiplash or an acute back sprain, recurrent episodes of pain separated by pain-free periods are common.11,18,31 Although the mechanisms for pain recurrence are unclear, unresolved tissue pathology is not considered a driving factor.24 (Source: The Journal of Pain)
Source: The Journal of Pain - May 17, 2018 Category: Materials Science Authors: Thorvaldur Skuli Palsson, Shellie A. Boudreau, Hans J ørgen Krebs, Thomas Graven-Nielsen Tags: Original Report Source Type: research

Parent responses to child pain during Intensive Interdisciplinary Pain Treatment and 1 Year Follow-up,, ✯✯✯
Impairment in youth with chronic pain is impacted by observable and unobservable (e.g. emotional and cognitive) behaviors of those around them 11,26, particularly their caregivers. Parents and other caregivers are integral to the social context of all youth, including those with chronic pain 48. Unfortunately, parents of youth with chronic pain often experience increased levels of emotional distress, interpersonal difficulties, and financial hardships 14,17,31, which may impair their ability to respond effectively to their child's pain. (Source: The Journal of Pain)
Source: The Journal of Pain - May 17, 2018 Category: Materials Science Authors: Melissa Pielech, Dustin P. Wallace, Megan Fitzgerald, Cara M. Hoffart Source Type: research

Acceptance and Commitment Therapy for Prevention of Chronic Post-surgical Pain and Opioid Use in At-Risk Veterans: A Pilot Randomized Controlled Study
Chronic post-surgical pain (CPSP) is a common and debilitating problem that occurs in 5-85% of patients following a variety of surgeries.22 Orthopedic surgeries are consistently associated with high postoperative pain, with the prevalence of chronic pain at 3 –24 months to be 20% or more after Total Knee Arthroplasty (TKA) and 8% or more after Total Hip Arthroplasty (THA).2,4,43,33,11 Disabling pain has a dramatic impact on functioning, quality of life, mood, sleep, cognitive functions and social life. (Source: The Journal of Pain)
Source: The Journal of Pain - May 17, 2018 Category: Materials Science Authors: Lilian Dindo, M. Bridget Zimmerman, Katherine Hadlandsmyth, Barbara StMarie, Jennie Embree, James Marchman, Toni Tripp-Reimer, Barbara Rakel Source Type: research

Ultrasound-Guided Application of Percutaneous Electrolysis as an Adjunct to Exercise and Manual Therapy for Subacromial Pain Syndrome: a Randomized Clinical Trial,
Subacromial pain syndrome, as a main cause of shoulder pain is a significant health problem and has a point prevalence ranging from 7% to 26% in the general population depending on the diagnostic criteria used in the study.23 The annual costs of shoulder pain symptoms is estimated to be 345 € million per year in primary health care.22 (Source: The Journal of Pain)
Source: The Journal of Pain - May 17, 2018 Category: Materials Science Authors: Lorena de-Miguel-Valtierra, Jaime Salom-Moreno, C ésar Fernández-de-las-Peñas, Joshua A. Cleland, José L. Arias-Buría Source Type: research