Cancers, Vol. 16, Pages 1374: MGMT Methylation and Differential Survival Impact by Sex in Glioblastoma

Conclusions: In this study, females had higher mean and individual CpG site methylation and received a greater PFS and OS benefit by MGMT methylation that was not seen in males despite equal degrees of CpG methylation.

Source: Cancers - March 31, 2024 Category: Cancer & Oncology Authors: Addison E. Barnett Ahmad Ozair Anas S. Bamashmos Hong Li David S. Bosler Gabrielle Yeaney Assad Ali David M. Peereboom Justin D. Lathia Manmeet S. Ahluwalia Tags: Article Source Type: research