An acute phase reaction from zoledronate mimicking symptoms seen in opioid withdrawal: a case report
CONCLUSION: Zoledronate, well known for causing acute phase reactions, was likely the cause of withdrawal-like symptoms. Acute phase reactions with bisphosphonates mostly occur in the first infusion, and the incidence decreases with subsequent infusions. Symptoms typically occur 24-72 h post-infusion, and last at most for 72 h. Cognitive bias led the primary team to be concerned with opioid withdrawal rather than investigating other causes for the patient's presentation. Therefore, providers should thoroughly investigate potential etiologies and rule them out accordingly to provide the best care. Health care providers shou...
Source: Addiction Science and Clinical Practice - May 1, 2024 Category: Addiction Authors: Pankti P Acharya Crystal Joseph Source Type: research
Role of antioxidants in the neurobiology of drug addiction: An update
Biomed Pharmacother. 2024 Apr 30;175:116604. doi: 10.1016/j.biopha.2024.116604. Online ahead of print.ABSTRACTRelationships between protective enzymatic and non-enzymatic pro-antioxidant mechanisms and addictive substances use disorders (SUDs) are analyzed here, based on the results of previous research, as well as on the basis of our current own studies. This review introduces new aspects of comparative analysis of associations of pro-antixidant and neurobiological effects in patients taking psychoactive substances and complements very limited knowledge about relationships with SUDs from different regions, mainly Europe. ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - May 1, 2024 Category: Drugs & Pharmacology Authors: Piotr Kami ński Ma łgorzata Lorek J ędrzej Baszyński Tadeusz Tadrowski Edward Jacek Gorzela ńczyk Julia Feit Halina Tkaczenko Jakub Owoc Alina Wo źniak Natalia Kurhaluk Source Type: research
The effects of alcohol use on smoking cessation treatment with nicotine replacement therapy: An observational study
CONCLUSION: Heavy, hazardous alcohol use is associated with lower odds of successfully quitting smoking compared to low or non-use of alcohol. Targeting alcohol treatment to this group may improve tobacco cessation outcomes.PMID:38692071 | DOI:10.1016/j.addbeh.2024.108045 (Source: Addictive Behaviors)
Source: Addictive Behaviors - May 1, 2024 Category: Addiction Authors: Benjamin K C Wong Scott Veldhuizen Nadia Minian Laurie Zawertailo Peter Selby Source Type: research
Long-term effects of alcohol consumption on anxiety in adults: A systematic review
CONCLUSIONS: A paucity of research on the longitudinal effects of alcohol consumption on anxiety was found, highlighting a significant gap in the research literature. Furthermore, existing research, primarily focussed on clinical subpopulations, has yielded mixed results. Further research is needed to explore the longitudinal dose dependent impact of alcohol consumption on anxiety using samples representative of national populations.PMID:38692070 | DOI:10.1016/j.addbeh.2024.108047 (Source: Addictive Behaviors)
Source: Addictive Behaviors - May 1, 2024 Category: Addiction Authors: Simon D'Aquino Akaash Kumar Benjamin Riordan Sarah Callinan Source Type: research
An acute phase reaction from zoledronate mimicking symptoms seen in opioid withdrawal: a case report
CONCLUSION: Zoledronate, well known for causing acute phase reactions, was likely the cause of withdrawal-like symptoms. Acute phase reactions with bisphosphonates mostly occur in the first infusion, and the incidence decreases with subsequent infusions. Symptoms typically occur 24-72 h post-infusion, and last at most for 72 h. Cognitive bias led the primary team to be concerned with opioid withdrawal rather than investigating other causes for the patient's presentation. Therefore, providers should thoroughly investigate potential etiologies and rule them out accordingly to provide the best care. Health care providers shou...
Source: Addiction Science and Clinical Practice - May 1, 2024 Category: Addiction Authors: Pankti P Acharya Crystal Joseph Source Type: research
Role of antioxidants in the neurobiology of drug addiction: An update
Biomed Pharmacother. 2024 Apr 30;175:116604. doi: 10.1016/j.biopha.2024.116604. Online ahead of print.ABSTRACTRelationships between protective enzymatic and non-enzymatic pro-antioxidant mechanisms and addictive substances use disorders (SUDs) are analyzed here, based on the results of previous research, as well as on the basis of our current own studies. This review introduces new aspects of comparative analysis of associations of pro-antixidant and neurobiological effects in patients taking psychoactive substances and complements very limited knowledge about relationships with SUDs from different regions, mainly Europe. ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - May 1, 2024 Category: Drugs & Pharmacology Authors: Piotr Kami ński Ma łgorzata Lorek J ędrzej Baszyński Tadeusz Tadrowski Edward Jacek Gorzela ńczyk Julia Feit Halina Tkaczenko Jakub Owoc Alina Wo źniak Natalia Kurhaluk Source Type: research
Long-term effects of alcohol consumption on anxiety in adults: A systematic review
CONCLUSIONS: A paucity of research on the longitudinal effects of alcohol consumption on anxiety was found, highlighting a significant gap in the research literature. Furthermore, existing research, primarily focussed on clinical subpopulations, has yielded mixed results. Further research is needed to explore the longitudinal dose dependent impact of alcohol consumption on anxiety using samples representative of national populations.PMID:38692070 | DOI:10.1016/j.addbeh.2024.108047 (Source: Addictive Behaviors)
Source: Addictive Behaviors - May 1, 2024 Category: Addiction Authors: Simon D'Aquino Akaash Kumar Benjamin Riordan Sarah Callinan Source Type: research
The effects of alcohol use on smoking cessation treatment with nicotine replacement therapy: An observational study
CONCLUSION: Heavy, hazardous alcohol use is associated with lower odds of successfully quitting smoking compared to low or non-use of alcohol. Targeting alcohol treatment to this group may improve tobacco cessation outcomes.PMID:38692071 | DOI:10.1016/j.addbeh.2024.108045 (Source: Addictive Behaviors)
Source: Addictive Behaviors - May 1, 2024 Category: Addiction Authors: Benjamin K C Wong Scott Veldhuizen Nadia Minian Laurie Zawertailo Peter Selby Source Type: research
An acute phase reaction from zoledronate mimicking symptoms seen in opioid withdrawal: a case report
CONCLUSION: Zoledronate, well known for causing acute phase reactions, was likely the cause of withdrawal-like symptoms. Acute phase reactions with bisphosphonates mostly occur in the first infusion, and the incidence decreases with subsequent infusions. Symptoms typically occur 24-72 h post-infusion, and last at most for 72 h. Cognitive bias led the primary team to be concerned with opioid withdrawal rather than investigating other causes for the patient's presentation. Therefore, providers should thoroughly investigate potential etiologies and rule them out accordingly to provide the best care. Health care providers shou...
Source: Addiction Science and Clinical Practice - May 1, 2024 Category: Addiction Authors: Pankti P Acharya Crystal Joseph Source Type: research
Substance Use Disorders and Addiction in the Emergency Care Setting
According to the American Society of Addiction Medicine, substance use disorder (SUD) is described as a “cluster of cognitive, behavioral, and physiological symptoms indicating that the individual continues to use alcohol, nicotine, and/or other drugs despite significant related problems” (the American Society of Addiction Medicine national practice guideline for the treatment of opioid use disord er: 2020 focused update, 2020, p. 7). Even with extensive evidence of the devastation that substance abuse has on lives and livelihood and the impact use, abuse, and addiction have on our emergency departments, substance use ...
Source: Journal of Emergency Nursing: JEN - May 1, 2024 Category: Nursing Authors: Dawn Peta Tags: ENA Position Statement Source Type: research
The effectiveness of a standardized tobacco cessation program on psychophysiological parameters in patients with addiction undergoing long-term rehabilitation: a quasi-experimental pilot study
Although there is a very high comorbidity between tobacco dependence and other addictive disorders, there are only few studies examining the implementation and outcomes of a tobacco cessation program in patien... (Source: BMC Medicine)
Source: BMC Medicine - May 1, 2024 Category: Internal Medicine Authors: J. Fuchshuber, H. Sch öber, M. Wohlmuth, H. Senra, C. Rominger, A. Schwerdtfeger and H. F. Unterrainer Tags: Research article Source Type: research
What Do We Know About Informal Caregiving in the Field of Addiction?: A Scoping Review
AbstractSubstance use disorder (SUD) and gambling disorder (GD) pose extensive challenges across various aspects of the affected person ’s life and those around them, generating significant public health concerns. Evolving perspectives have led to a shift in nomenclature, with some authors adopting the term “caregivers” to diminish stigma and enhance service accessibility. This systematic literature review aims to offer a comp rehensive overview of informal caregivers for adults with addictions. Analyzing 79 retained articles through a scoping review, encompassing both scientific and gray literature, five key finding...
Source: International Journal of Mental Health and Addiction - May 1, 2024 Category: Addiction Source Type: research
Optimal [18F]FDG PET/CT Cutoff for Pathologic Complete Response in HER2-Positive Early Breast Cancer Patients Treated with Neoadjuvant Trastuzumab and Pertuzumab in the PHERGain Trial
Conclusion: In the PHERGain trial, an increased SUVmax cutoff (≥77%) after 2 cycles of exclusive HP (with or without endocrine therapy) achieves a pCR in the range of the control arm with chemotherapy plus HP (59.5% vs. 57.7%, respectively), further identifying a subgroup of patients with HER2-addicted tumors. However, the original cutoff (≥40%) maximizes the number of patients who could avoid chemotherapy. (Source: Journal of Nuclear Medicine)
Source: Journal of Nuclear Medicine - May 1, 2024 Category: Nuclear Medicine Authors: Gebhart, G., Keyaerts, M., Guiot, T., Flamen, P., Ruiz-Borrego, M., Stradella, A., Bermejo, B., Escriva-de-Romani, S., Calvo Martinez, L., Ribelles, N., Fernandez-Abad, M., Albacar, C., Colleoni, M., Garrigos, L., Atienza de Frutos, M., Dalenc, F., Prat, Tags: Clinical Investigations Source Type: research
Understanding Public Perception of Naloxone: A Study of FAQs and Answer Source Credibility
CONCLUSION: We identified FAQs and their citations about naloxone, highlighting potential lack of understanding and knowledge of this important intervention. We recommend updating websites to accurately reflect current and useful information for those that may require naloxone.PMID:38688898 | DOI:10.1080/10826084.2024.2341319 (Source: Substance Use and Misuse)
Source: Substance Use and Misuse - April 30, 2024 Category: Addiction Authors: Sydney C Ferrell Matthew C Ferrell Cole M Nelson Justin S Lippard Jason Beaman Matt Vassar Source Type: research
Provider-patient relationships and trauma among pregnant patients with opioid-use disorder
CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Analyses show an association between probable PTSD and provider-patient relationship among pregnant patients with OUD, with those with probable PTSD having a worse alliance with obstetric providers. This novel finding helps characterize the provider-patient relationship among a uniquely vulnerable population and can inform efforts to integrate trauma-informed practices into prenatal care.PMID:38685767 | DOI:10.1111/ajad.13570 (Source: American Journal on Addictions)
Source: American Journal on Addictions - April 30, 2024 Category: Addiction Authors: Molly Doernberg Kathryn Gilstad-Hayden Kimberly A Yonkers Ariadna Forray Source Type: research
