Effectiveness of a self-determination theory-based smoking cessation intervention plus instant messaging via mobile application for smokers with cancer: Protocol for a pragmatic randomized controlled trial
Addiction. 2024 May 6. doi: 10.1111/add.16521. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Despite evidence that patients living with cancer who continue to smoke after diagnosis are at higher risk for all-cause mortality and reduced treatment efficacy, many cancer patients continue to smoke. This protocol is for a study to test the effectiveness of a self-determination theory-based intervention (quit immediately or progressively) plus instant messaging (WhatsApp or WeChat) to help smokers with cancer to quit smoking.DESIGN: This will be a multi-centre, two-arm (1:1), single-blind, pragmatic, individually randomized...
Source: Cancer Control - May 6, 2024 Category: Cancer & Oncology Authors: William Ho Cheung Li David Chi Leung Lam Kit Man Sin Eliza Lai Yi Wong Carlos King Ho Wong Herbert Ho Fung Loong Kai Yeung Cheung Wei Xia Peige Song Joyce Oi Kwan Chung Source Type: research

Acupuncture in the treatment of cocaine addiction: how does it work?
This article mainly focuses on the neurobiological mechanisms involving the central nervous system (CNS) and peripheral nervous system (PNS) that underlie the effects of acupuncture in the treatment of cocaine addiction. The central dopamine system is a key player in acupuncture treatment of cocaine addiction; the ventral tegmental area (VTA)-nucleus accumbens (NAc) signaling pathway, which has a modulatory influence on behavior and psychology after chronic use of cocaine, is a significant target of acupuncture action. Moreover, acupuncture alleviates cocaine-induced seizures or acute psychomotor responses through the para...
Source: Acupuncture in Medicine - May 6, 2024 Category: Complementary Medicine Authors: Luqiang Sun Haichuan Wang Source Type: research

Associations of Impulsivity and Risky Decision-Making with E-Cigarette-Related Outcomes Among Adolescents with Congenital Heart Disease: Variable- and Person-Oriented Approaches
Behav Med. 2024 May 6:1-12. doi: 10.1080/08964289.2024.2347226. Online ahead of print.ABSTRACTAdolescents with congenital heart disease (CHD) have elevated risk for acquired cardiovascular complications, increasing their vulnerability to e-cigarette-related health harms. Impulsivity and risky decision-making have been associated with adolescent substance use, but the relationships between these factors and e-cigarette-related outcomes among cardiovascular at-risk adolescents with CHD are unknown. This cross-sectional study aimed to (a) determine the associations of impulsivity and risky decision-making with e-cigarette-rel...
Source: Behavioral Medicine - May 6, 2024 Category: Psychiatry Authors: Kristen R Fox Joseph R Rausch Victoria R Grant Amy K Ferketich Judith A Groner Vidu Garg Clifford L Cua Jamie L Jackson Source Type: research

Drugs and Addiction Science: NIDA Celebrates 50 Years of Research and Looks to the Future
Am J Psychiatry. 2024 May 1;181(5):349-352. doi: 10.1176/appi.ajp.20230880.NO ABSTRACTPMID:38706329 | DOI:10.1176/appi.ajp.20230880 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - May 6, 2024 Category: Psychiatry Authors: Nora D Volkow Source Type: research

Substance Use Disorders: Confronting Addiction From Prevention to Recovery
Am J Psychiatry. 2024 May 1;181(5):347-348. doi: 10.1176/appi.ajp.20240221.NO ABSTRACTPMID:38706333 | DOI:10.1176/appi.ajp.20240221 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - May 6, 2024 Category: Psychiatry Authors: Kathleen T Brady Ned H Kalin Source Type: research

Understanding and Addressing Widening Racial Inequalities in Drug Overdose
Am J Psychiatry. 2024 May 1;181(5):381-390. doi: 10.1176/appi.ajp.20230917.ABSTRACTThe fourth wave of the United States overdose crisis-driven by the polysubstance use of fentanyl with stimulants and other synthetic substances-has driven sharply escalating racial/ethnic inequalities in drug overdose death rates. Here the authors present a detailed portrait of the latest overdose trends and synthesize the literature to describe where, how, and why these inequalities are worsening. By 2022 overdose deaths among Native and Black Americans rose to 1.8 and 1.4 times the rate seen among White Americans, respectively. This reflec...
Source: The American Journal of Psychiatry - May 6, 2024 Category: Psychiatry Authors: Joseph R Friedman Max Jordan Nguemeni Tiako Helena Hansen Source Type: research

Drugs and Addiction Science: NIDA Celebrates 50 Years of Research and Looks to the Future
American Journal of Psychiatry,Volume 181, Issue 5, Page 349-352, May 01, 2024. (Source: American Journal of Psychiatry)
Source: American Journal of Psychiatry - May 6, 2024 Category: Psychiatry Authors: Nora D. Volkow Source Type: research

Substance Use Disorders: Confronting Addiction From Prevention to Recovery
American Journal of Psychiatry,Volume 181, Issue 5, Page 347-348, May 01, 2024. (Source: American Journal of Psychiatry)
Source: American Journal of Psychiatry - May 6, 2024 Category: Psychiatry Authors: Kathleen T. Brady Ned H. Kalin Source Type: research

A qualitative study of experiences with physical activity among people receiving opioid agonist therapy
Physical or mental health comorbidities are common among people with substance use disorders undergoing opioid agonist therapy. As both a preventive and treatment strategy, exercise offers various health benef... (Source: Substance Abuse Treatment, Prevention, and Policy)
Source: Substance Abuse Treatment, Prevention, and Policy - May 6, 2024 Category: Addiction Authors: Einar Furulund, Siv-Elin Leirv åg Carlsen, Karl Trygve Druckrey-Fiskaaen, Tesfaye Madebo, Lars T Fadnes and Torgeir Gilje Lid Tags: Research Source Type: research

Time for a Focus on Cessation of E-Cigarettes
E-cigarettes, which were introduced in the US market in 2007, have experienced tremendous growth in the US and globally and are the focus of an intense and often controversial public health debate concerning harms and benefits. The most important potential benefit of e-cigarettes is to assist with cigarette smoking cessation and reduce exposure to cigarette-related harm among those who completely switch to e-cigarettes. However, e-cigarettes can also produce harm and serve to initiate and maintain nicotine addiction in populations for whom there is no potential public health benefit of use. Indeed, e-cigarette use prevalen...
Source: JAMA Internal Medicine - May 6, 2024 Category: Internal Medicine Source Type: research

Individual Trajectories of Specialist Substance Use Disorder and Mental Health Treatment Utilization Among Young Adults With Substance Use Problems: A Cohort Study
CONCLUSIONS: Results demonstrated significant variation in trajectories of treatment use among young adults with substance use disorder. Differences in treatment use could indicate differences in symptom severity and complexity. In this study, treatment use was associated with socioeconomic factors, sex, and age. Integrative approaches, including interagency and interdisciplinary collaboration, will often be necessary to sufficiently address the multidimensionality of substance use disorder.PMID:38704859 | DOI:10.1080/15504263.2024.2341092 (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - May 5, 2024 Category: Addiction Authors: Regine Bakken J ūratė Š Benth Halvor Fauske Lars Lien Anne S Landheim Source Type: research

Nationwide Assessment of Chronic Pain among Hospitalized Individuals with Co-occurring Post Traumatic Stress Disorder and Substance Use Disorder in the United States
Conclusions: Among hospitalized Americans with co-occurring PTSD and SUD, advanced age, being female, and the presence other mental health disorders were associated with an increased risk of CP. Providers treating co-occurring PTSD/SUD should evaluate for and consider evidence-based management of CP if present.PMID:38704860 | DOI:10.1080/15504263.2024.2347489 (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - May 5, 2024 Category: Addiction Authors: Olaniyi Olayinka Brook T Alemu Stanley Nkemjika Declan T Barry Source Type: research

Non-oncogene dependencies: Novel opportunities for cancer therapy
Biochem Pharmacol. 2024 May 2:116254. doi: 10.1016/j.bcp.2024.116254. Online ahead of print.ABSTRACTTargeting oncogene addictions have changed the history of subsets of malignancies and continues to represent an excellent therapeutic opportunity. Nonetheless, alternative strategies are required to treat malignancies driven by undruggable oncogenes or loss of tumor suppressor genes and to overcome drug resistance also occurring in cancers addicted to actionable drivers. The discovery of non-oncogene addiction (NOA) uncovered novel therapeutically exploitable "Achilles' heels". NOA refers to genes/pathways not oncogenic per ...
Source: Biochemical Pharmacology - May 4, 2024 Category: Drugs & Pharmacology Authors: Tiziana Di Marco Mara Mazzoni Angela Greco Giuliana Cassinelli Source Type: research

Non-oncogene dependencies: Novel opportunities for cancer therapy
Biochem Pharmacol. 2024 May 2:116254. doi: 10.1016/j.bcp.2024.116254. Online ahead of print.ABSTRACTTargeting oncogene addictions have changed the history of subsets of malignancies and continues to represent an excellent therapeutic opportunity. Nonetheless, alternative strategies are required to treat malignancies driven by undruggable oncogenes or loss of tumor suppressor genes and to overcome drug resistance also occurring in cancers addicted to actionable drivers. The discovery of non-oncogene addiction (NOA) uncovered novel therapeutically exploitable "Achilles' heels". NOA refers to genes/pathways not oncogenic per ...
Source: Biochemical Pharmacology - May 4, 2024 Category: Drugs & Pharmacology Authors: Tiziana Di Marco Mara Mazzoni Angela Greco Giuliana Cassinelli Source Type: research

Hobbies, Distractions, Obsessions, and Addictions
A career in cardiothoracic surgery takes a psychological and emotional toll, which is likely increased by recent changes in our health care environment. The benefits of leisure pursuits are severalfold, one of which includes supporting physician wellness. However, we are at risk of relying on unhealthy mechanisms to provide relief. The incidence of addiction and substance abuse is high, particularly among women surgeons. There are a variety of opportunities to help ourselves and support our colleagues. We need to promote healthy activities outside of our profession for the long-term well-being of cardiothoracic surgeons an...
Source: Thoracic Surgery Clinics - May 4, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Shubham Gulati, M. Blair Marshall Source Type: research