FDA Issues Warning About 'Gas Station Heroin'
Am J Nurs. 2024 May 1;124(5):13. doi: 10.1097/01.NAJ.0001016316.12810.5d. Epub 2024 Apr 25.ABSTRACTThe highly addictive dietary supplement mimics opioid effects.PMID:38661686 | DOI:10.1097/01.NAJ.0001016316.12810.5d (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - April 25, 2024 Category: Nursing Authors: Karen Roush Source Type: research
Chromosomal 3q amplicon encodes essential regulators of secretory vesicles that drive secretory addiction in cancer
J Clin Invest. 2024 Apr 25:e176355. doi: 10.1172/JCI176355. Online ahead of print.ABSTRACTCancer cells exhibit heightened secretory states that drive tumor progression. Here, we identify a chromosome 3q amplicon that serves as a platform for secretory regulation in cancer. The 3q amplicon encodes multiple Golgi-resident proteins, including the scaffold Golgi integral membrane protein 4 (GOLIM4) and the ion channel ATPase Secretory Pathway Ca2+ Transporting 1 (ATP2C1). We show that GOLIM4 recruits ATP2C1 and Golgi phosphoprotein 3 (GOLPH3) to coordinate calcium-dependent cargo loading and Golgi membrane bending and vesicle ...
Source: Clinical Lung Cancer - April 25, 2024 Category: Cancer & Oncology Authors: Xiaochao Tan Shike Wang Guan-Yu Xiao Chao Wu Xin Liu Biyao Zhou Jiang Yu Dzifa Yawa Duose Yuanxin Xi Jing Wang Kunika Gupta Apar Pataer Jack A Roth Michael P Kim Fengju Chen Chad J Creighton William K Russell Jonathan M Kurie Source Type: research
Secondhand harms from cannabis use: Findings from Washington State, United States
CONCLUSIONS: Augmenting research on individual harms associated with cannabis use by including secondhand impacts such as social and family problems, along with safety risks, provides a more comprehensive picture of the effects of cannabis use.PMID:38662514 | DOI:10.15288/jsad.23-00342 (Source: Journal of Studies on Alcohol and Drugs)
Source: Journal of Studies on Alcohol and Drugs - April 25, 2024 Category: Addiction Authors: Thomas K Greenfield Christina C Tam William C Kerr Source Type: research
The Role of Positive and Negative Affect in Illicit Substance Use and Alcohol Use: An Ecological Momentary Assessment Study
CONCLUSION: This study further supported the relation between positive affect and both alcohol and illicit substance use.PMID:38662516 | DOI:10.15288/jsad.23-00067 (Source: Journal of Studies on Alcohol and Drugs)
Source: Journal of Studies on Alcohol and Drugs - April 25, 2024 Category: Addiction Authors: Konrad Bresin Olivia Hatfield Michaela S Ahrenholtz Edelyn Verona Source Type: research
Environmental Suppression Mediates the Relationship between Posttraumatic Stress and Cannabis Use Among Trauma-Exposed College Students
CONCLUSIONS: Results support the utility of the RPI-ES scale as a transdiagnostic risk factor for both PTS and cannabis use and suggest further investigation into treatment approaches that optimize opportunities for (non-substance) rewarding experiences in the treatment of co-occurring PTS and substance misuse.PMID:38662506 | DOI:10.15288/jsad.23-00344 (Source: Journal of Studies on Alcohol and Drugs)
Source: Journal of Studies on Alcohol and Drugs - April 25, 2024 Category: Addiction Authors: Michael Gawrysiak Daniel Loomis Sebastian Ehmann Sam Wayne Mikaela Armao Source Type: research
Sweet taste preference as a moderator of links between internalizing symptoms and alcohol craving
CONCLUSIONS: For those low and moderate in sweet taste preference, internalizing symptoms appeared positively linked with alcohol craving. For those high in sweet taste preference, alcohol craving remained elevated regardless of anxiety symptoms, but appeared to decrease with heightened depressive symptoms. Should future research replicate this finding using controlled research designs that demonstrate temporality and causality, tailored early AUD interventions may be justified based on individuals' levels of sweet taste preference.PMID:38662513 | DOI:10.15288/jsad.23-00107 (Source: Journal of Studies on Alcohol and Drugs)
Source: Journal of Studies on Alcohol and Drugs - April 25, 2024 Category: Addiction Authors: Brianna R Altman Tosca D Braun Cynthia L Battle Michael D Stein Sarah Barter Sydney Iacoi Ryan Koch Ana M Abrantes Source Type: research
Gratification and its associations with problematic internet use: A systematic review and meta-analysis using Use and Gratification theory
This study aimed to synthesize research findings applying UGT and pinpoint the associations between different gratifications and PIU. Effect sizes were pooled to obtain an overall effect size. Gratifications were then classified into four types (i.e., content, social, self-presentation, and process) according to the suggestions of previous studies and the measurement of included studies. Based on 216 effect sizes from 57 samples with 38,492 participants (mean age = 24.3; 55.1 % female), random effect model analyses yielded a medium effect size (r = 0.303, p <.001, 95 % CI [0.263, 0.343]), indicating a positive associati...
Source: Addictive Behaviors - April 25, 2024 Category: Addiction Authors: Dannuo Wei Lik-Sam Chan Nan Du Xiujing Hu Yu-Te Huang Source Type: research
Cannabis Use Characteristics Associated with Self-Reported Cognitive Function in a Nationally Representative U.S. sample
CONCLUSION: While prospective studies are required to confirm, findings suggest cannabis use is linked to worse cognition. There may be some limited recovery of cognition in former users and some cannabis use characteristics predict impairment. These findings add to our understanding of the cognitive impact of cannabis use. As worse cognitive function may impact relapse, findings have implications for personalization of cannabis use disorder treatment.PMID:38664196 | DOI:10.1080/10826084.2024.2340975 (Source: Substance Use and Misuse)
Source: Substance Use and Misuse - April 25, 2024 Category: Addiction Authors: Dafna Sara Rubin-Kahana Kevin Butler Ahmed Nabeel Hassan Marcos Sanches Bernard Le Foll Source Type: research
FDA Issues Warning About 'Gas Station Heroin'
Am J Nurs. 2024 May 1;124(5):13. doi: 10.1097/01.NAJ.0001016316.12810.5d. Epub 2024 Apr 25.ABSTRACTThe highly addictive dietary supplement mimics opioid effects.PMID:38661686 | DOI:10.1097/01.NAJ.0001016316.12810.5d (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - April 25, 2024 Category: Nursing Authors: Karen Roush Source Type: research
Experiences of Stigma and Discrimination Compounded by Intersecting Identities among Individuals Receiving Medication for Opioid Use Disorder
We report qualitative findings from a mixed methods study guided by three aims: to explore (1) intersecting identities of people receiving MOUD (2) how individuals experience stigma and discrimination and (3) helpful resources in addressing cumulative experiences of multiple forms of disadvantage. We conducted interviews with 25 individuals in three treatment centers in the Northeast United States and identified six themes: (1) Living with multiple socially marginalized identities and addiction; (2) Loss; (3) "It's everywhere": Discrimination and stigma; (4) A "damaged" identity, (5) Positive responses to negative experien...
Source: Journal of Health Care for the Poor and Underserved - April 25, 2024 Category: International Medicine & Public Health Authors: Uzoji Nwanaji-Enwerem Nancy S Redeker Meghan O'Connell Declan Barry Theddeus Iheanacho Tish M Knobf Dustin Scheinost Katie Wang Klar Yaggi Lois S Sadler Source Type: research
Alterations in the fecal microbiota of methamphetamine users with bad sleep quality during abstinence
Methamphetamine (MA) abuse has resulted in a plethora of social issues. Sleep disturbance is a prominent issue about MA addiction, which serve as a risk factor for relapse, and the gut microbiota could play an... (Source: BMC Psychiatry)
Source: BMC Psychiatry - April 25, 2024 Category: Psychiatry Authors: Zijing Deng, Linzi Liu, Wen Liu, Ruina Liu, Tao Ma, Yide Xin, Yu Xie, Yifan Zhang, Yifang Zhou and Yanqing Tang Tags: Research Source Type: research
Prevalence and factors associated with digital addiction among students taking university entrance tests: a GIS-based study
The surge in digital media consumption, coupled with the ensuing consequences of digital addiction, has witnessed a rapid increase, particularly after the initiation of the COVID-19 pandemic. Despite some stud... (Source: BMC Psychiatry)
Source: BMC Psychiatry - April 25, 2024 Category: Psychiatry Authors: Firoj Al-Mamun, Md Emran Hasan, Nahida Bintee Mostofa, Marzia Akther, Tahnin Mashruba, Mohammad Arif, Amatul Haque Chaahat, Anha Bushra Salam, Maksuda Akter, Md Al Asif Abedin, Md. Imtiaj Ahmad Bulbul, Md Shoeb Adnan, Md. Shafiul Islam, Mst. Shauda Ahmed, Tags: Research Source Type: research
Psychotherapeutic Interventions in Clinical Trials of Psychedelics for the Treatment of Alcohol Use Disorder
AbstractPurpose of ReviewAlcohol use disorder (AUD) is the most common substance use disorder in the USA, with a considerable burden of disease. In recent years, psychedelics have emerged as particularly promising in treating AUD. In this paper, we review trials of classic and non-classic psychedelics in the treatment of AUD to determine whether there is substantial evidence, either confirming or refuting the need for accompanying psychotherapy on clinical effect for the treatment of AUD and whether any of the therapy methods are superior to others in this context.Recent FindingsWe found no study directly comparing differe...
Source: Current Addiction Reports - April 25, 2024 Category: Addiction Source Type: research
Men of Mexican ethnicity, alcohol use, and help-seeking: “I can quit on my own.”
Hispanics report higher rates of problematic alcohol use compared to non-Hispanic Whites while also reporting lower rates of alcohol treatment utilization compared to non-Hispanics. The study employs Anderson's Behavioral Model of Healthcare Utilization Model to guide the exploration of alcohol use, help-seeking and healthcare utilization. (Source: Journal of Substance Abuse Treatment)
Source: Journal of Substance Abuse Treatment - April 25, 2024 Category: Addiction Authors: Eden Hernandez Robles, Yessenia Castro, Sarah Najera, Juliana Cardoso, Rubi Gonzales, Jason Mallonee, Javier Segovia, Leslie Hinojosa-Salazar, Cecilia De Vargas, Craig Field Source Type: research
Mining clinical data for novel medications to treat alcohol use disorder
Alcohol use disorder (AUD) is a highly prevalent and often debilitating condition associated with high morbidity and mortality. Current AUD medications have limited efficacy and uptake. Alternative pharmacological options are needed. (Source: Journal of Substance Abuse Treatment)
Source: Journal of Substance Abuse Treatment - April 25, 2024 Category: Addiction Authors: Luke Rozema, Jessica E. Hoyt, Bradley V. Watts, Brian Shiner Source Type: research
